Labshake search
Citations for Tocris :
1001 - 1045 of 1045 citations for 6 methyl 2 thioxo 2 3 dihydroquinazolin 4 1H one since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Neuroscience 2020Quote: ... placed in an aCSF-filled borosilicate glass pipette (3-5 MΩ) in the presence of 6,7-Dinitroquinoxaline-2,3-dione (DNQX; 10 μM; Tocris #14A/166549).
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bioRxiv - Neuroscience 2021Quote: ... Hox propagation was initiated by activation of Wnt signaling using NMP media comprised of E6 medium supplemented with 200 ng/mL FGF8b and 3 μM CHIR99021 (Tocris). This constitutes the “Hox timepoint” of 0hrs ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... 0.3 or 1 mg/kg of the mGlu2/3 receptor agonist LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience ...
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bioRxiv - Neuroscience 2022Quote: ... 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolol[1,5-a]pyrimidin-3-yl]phenol (PHTPP, 10 μM dissolved in 10% DMSO, TOCRIS, Minneapolis, MN), microinjected bilaterally into the CeA (0.5 μL over one minute with a one-minute wait post-infusion ...
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bioRxiv - Bioengineering 2023Quote: ... The media were changed at day 3 to remove the ROCK inhibitor and to add 10 µM DAPT (Tocris Bioscience), which remained until day 7 ...
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bioRxiv - Cell Biology 2023Quote: iPSCs were first differentiated into iAT2s and passaged as above in 3D cultures in iAT2 medium (CK+DCI) supplemented for the first 3 days after passaging with 10 uM Y-27632 (Tocris). To generate iAT1s ...
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bioRxiv - Neuroscience 2023Quote: ... Extracellular action potentials were recorded in 3 independent cultures for either genotype in the presence of 50nM nifedipine (Tocris Bioscience) or vehicle using the MaestroPro (Axion Biosystems ...
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bioRxiv - Developmental Biology 2024Quote: Incretin mimetic drug treatments were performed by supplementing unmodified Arc-3 medium with Metformin hydrochloride at 10 µM (Tocris, 2864), Exendin-4 at 10 nM (Tocris ...
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bioRxiv - Neuroscience 2021Quote: ... Amyloid plaques were stained by the β-sheet dye Methoxy-X04 (4 μg/ml in 50% ethanol, Tocris) for 30 min at RT and contrasting in 50% ethanol ...
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bioRxiv - Neuroscience 2019Quote: ... The drugs used in this study are as follows: (±)-Bay K 8644 (catalog # 1544, Batch No. 4; Tocris), Nefiracetam (catalog # 2851 ...
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bioRxiv - Physiology 2023Quote: ... The dorsal muscle and skin were sutured with 4-0 sutures followed by injections of yohimbine (1.2 mg/kg, s.c.; Tocris), lactated Ringer’s solution (5 mL ...
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bioRxiv - Cell Biology 2020Quote: ... and diabetic NOD mice (14-26 weeks; n=3) were intra-peritoneally injected with 50mg/kg of Chloroquine diphosphate (Tocris #4109). Two hours post injection ...
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bioRxiv - Cell Biology 2021Quote: Receptors were stimulated as follows: human Angiotensin 1 receptor (AT1R) with Angiotensin II (AngII; Tocris 4474-91-3, in measuring buffer), human β2 adrenergic receptor (β2ADR ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: ... supplemented with 100 ng/mL Activin A (R&D, Minneapolis, MN, USA) and 3–5 µM CHIR99021 (Tocris Bioscience, Bristol, UK) (differentiation day 0 ...
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bioRxiv - Cell Biology 2020Quote: ... into fibronectin-coated wells of two 96 well plates per biological replicate to assess proliferation on day 0 (D0) and day 3 (D3) in the presence or absence of 10 μM RARβ antagonist LE135 (Tocris Bioscience) using the cell viability MTS assay ...
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bioRxiv - Cancer Biology 2024Quote: To induce the degradation of AID-NCL, cells were treated with 5-phenyl-indole-3-acetic acid (phenyl-auxin, 5-Ph-IAA) (Tocris, #7392). To block the interaction between APC/C and cdc20 ...
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bioRxiv - Neuroscience 2019Quote: ... a final group of animals (n=4) received a DBB infusion of K-234 (1 nmol/0.5 µl/per side; Tocris Bioscience ...
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bioRxiv - Developmental Biology 2022Quote: ... zebrafish embryos were dechorionated with 1mg/ml pronase at 9 hpf and washed thoroughly with fresh Danieau’s buffer before being treated with 10μM (Z)-4-hydroxytamoxifen (#3412, Tocris, UK) for 2h at 28°C in the dark ...
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bioRxiv - Neuroscience 2023Quote: ... L-glutamate was locally photo-released from 1 mM 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-glutamate, TOCRIS) using an OPTOLED pulse of 1 ms at 365 nM wavelength ...
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bioRxiv - Neuroscience 2021Quote: ... n=20) group were randomized to receive either saline or GLP-1R antagonist Exendin-3(9-39)amide (Ex-9) (Tocris Bioscience, UK) (85 μg/kg dissolved in saline ...
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bioRxiv - Genomics 2022Quote: ... iPS cells were grown to 80– 90% confluence and changed into CM Media supplemented with 3 μM CHIR99021 (Tocris Biosciences, Bristol, UK) for 2 days ...
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bioRxiv - Cancer Biology 2022Quote: ... Proteins were then transferred onto PVDF membranes (Cytiva, Catalog #: 10600023) using a wet transfer approach and membranes were then blocked with 3% bovine serum albumin (Tocris, Catalog #: 5217) and probed for CDC42 (Cell Signaling Technology ...
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bioRxiv - Cancer Biology 2024Quote: ... 3 males and 3 females) received a twice daily subcutaneous injection of 100 µL of 5 mg/kg mouse weight of AMG487 (Tocris, Cat# 448710) for 2 weeks ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Cell Biology 2021Quote: ... flow cytometer, and the fractions of stained cells were quantified using FloJo 10.6, with Staurosporine (4 h, 5 μM) (Tocris, 1285) used as a positive control for cell death and to help establish gating of the sorted cells.
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bioRxiv - Neuroscience 2021Quote: Structural plasticity of dendritic spines was stimulated through uncaging of 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris) using a Ti ...
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bioRxiv - Developmental Biology 2021Quote: ... Neural progenitors were briefly washed (with DMEM/F12) and were then treated with CDM2 basal media supplemented with CHIR99021 (4 μM; Tocris), SB-505124 (2 μM ...
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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bioRxiv - Neuroscience 2024Quote: ... was set to 720 nm and used to uncage 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris). Up to four spines in separate regions of interest (ROI ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Neuroscience 2024Quote: ... The cell suspension was then centrifuged at 1,200 rpm for 4 minutes and resuspended in mTeSR medium supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris Cat # 1254) at a concentration of 10,000 cells per 100 µL or 1 million cells per 10 mL ...
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bioRxiv - Developmental Biology 2022Quote: ... and 1% Pen/Strep) +2iLIF (10 ng/ml leukemia inhibitory factor + 3 μM CHIR99021 + 1 μM PD0325901 from Tocris, Cat. # 4423 and 4192, respectively). The cells were grown on 0.1% gelatin-coated dishes and usually seeded at a density of 0.5–1.5 × 104/cm2 ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...
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bioRxiv - Neuroscience 2020Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
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bioRxiv - Developmental Biology 2021Quote: ... (15) ESC were grown in N2B27 media supplemented with 2i/LIF (1 mM PD0325901, 3 mM CHIR99021, both from Tocris and 1:500 LIF, made in house). N2B27 media consisted of a 1:1 mix of DMEM/F12 and Neurobasal Medium ...
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bioRxiv - Neuroscience 2023Quote: ... we tested effects of an inhibitor (the spider toxin GsMTX 4; Tocris #4912 stock 50 μM in DMSO and the Piezo1 channel activator Yoda1 (Tocris 6586 10 and 20 uM, stock 20 mM in DMSO).