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Citations for Tocris :
951 - 1000 of 1093 citations for tert Butyl 2 chloro 5H pyrrolo 3 4 b pyridine 6 7H carboxylate since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Genomics 2023Quote: ... spent media was replaced with fresh CDM containing 2 µM Wnt-C59 (5148, Tocris Bioscience). CDM was used to replace media on Days 5 ...
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... the medium was replaced with differentiation medium containing 5 μM IWP-2 (TOCRIS, Cat.# 3533), a Wnt inhibitor ...
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bioRxiv - Immunology 2024Quote: ... 8-to 12-week-old mice were treated with 2 nmol calcipotriol (MC903, Tocris Bioscience) in 10 μL of 100% ethanol (EtOH ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... and (11R)-2-Methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraene (WIN55,212-2) were acquired from Tocris (Bristol, UK). [(1S,2S,5S)-2-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol (HU308 ...
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bioRxiv - Neuroscience 2024Quote: ... with a dosage of 2 mg/kg of Methoxy-X04 dye (Tocris Bioscience, Bristol, UK). In our setup ...
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bioRxiv - Neuroscience 2021Quote: ... n=20) group were randomized to receive either saline or GLP-1R antagonist Exendin-3(9-39)amide (Ex-9) (Tocris Bioscience, UK) (85 μg/kg dissolved in saline ...
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bioRxiv - Genomics 2022Quote: ... iPS cells were grown to 80– 90% confluence and changed into CM Media supplemented with 3 μM CHIR99021 (Tocris Biosciences, Bristol, UK) for 2 days ...
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bioRxiv - Cancer Biology 2022Quote: ... Proteins were then transferred onto PVDF membranes (Cytiva, Catalog #: 10600023) using a wet transfer approach and membranes were then blocked with 3% bovine serum albumin (Tocris, Catalog #: 5217) and probed for CDC42 (Cell Signaling Technology ...
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bioRxiv - Cancer Biology 2024Quote: ... 3 males and 3 females) received a twice daily subcutaneous injection of 100 µL of 5 mg/kg mouse weight of AMG487 (Tocris, Cat# 448710) for 2 weeks ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Cell Biology 2021Quote: ... flow cytometer, and the fractions of stained cells were quantified using FloJo 10.6, with Staurosporine (4 h, 5 μM) (Tocris, 1285) used as a positive control for cell death and to help establish gating of the sorted cells.
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bioRxiv - Neuroscience 2021Quote: Structural plasticity of dendritic spines was stimulated through uncaging of 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris) using a Ti ...
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bioRxiv - Developmental Biology 2021Quote: ... Neural progenitors were briefly washed (with DMEM/F12) and were then treated with CDM2 basal media supplemented with CHIR99021 (4 μM; Tocris), SB-505124 (2 μM ...
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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bioRxiv - Neuroscience 2024Quote: ... was set to 720 nm and used to uncage 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris). Up to four spines in separate regions of interest (ROI ...
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bioRxiv - Neuroscience 2024Quote: ... UNA fibroblasts were generated by transducing 500,000 dermal fibroblasts with 500 µl of the lentiviral vector stock in a T25 cell culture flask while adding 4 µg/ml polybrene (Tocris) to improve transduction efficiency ...
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bioRxiv - Neuroscience 2024Quote: ... and Cre expression was induced from P3 to P5 by daily intraperitoneal injections of 0.2 mg of 4-OHT (Tocris Bioscience) as previously described21 ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...
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bioRxiv - Cancer Biology 2022Quote: ... One hour before dsDNA transfection cells were pre-treated with 2 µM NU7441 (#3712, Biotechne/Tocris) in OptiMEM and were subsequently transfected with dsDNA (1 µg/ml) ...
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Developmental Biology 2021Quote: ... Lin- c-Kit+ cells were sorted into 2%FCS-PBS with 100µM IWR-1 (Tocris, 3532) or control vehicle ...
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bioRxiv - Microbiology 2020Quote: ... cells were pretreated for 3h before infection with Tautomycetin (0.8 μM, Tocris Bioscience, 119757-73-2) or Okadaic acid (0.1 μM ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Developmental Biology 2024Quote: ... Cells were treated as control or with 2 µM DDR1 inhibitor DDR1-in-1 (Tocris 5077) or 5 µM RUNX1 inhibitor AI-10-104 (Aobious AOB17076) ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2024Quote: ... 2-amino-5-phosphonopentanoic acid (AP5) (cat. # 0106) and picrotoxin (cat. # 1128) were purchased from Tocris. Barium chloride (BaCl2-2H2O ...
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bioRxiv - Neuroscience 2024Quote: ... supplemented with 1.25% DMSO and 1.25% Tween 80) or BMS-204352 (2 mg per kg, Tocris) were delivered by intraperitoneal injection 30 min before behavioral testing (as described previously Zhang) ...
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bioRxiv - Neuroscience 2024Quote: ... 2 weeks differentiated BMP4 and CNTF astrocytes were treated with ROCK inhibitor Y27632 (Tocris, 25 μM) or LAT B (Sigma ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Neuroscience 2024Quote: ... The cell suspension was then centrifuged at 1,200 rpm for 4 minutes and resuspended in mTeSR medium supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris Cat # 1254) at a concentration of 10,000 cells per 100 µL or 1 million cells per 10 mL ...
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bioRxiv - Developmental Biology 2022Quote: ... and 1% Pen/Strep) +2iLIF (10 ng/ml leukemia inhibitory factor + 3 μM CHIR99021 + 1 μM PD0325901 from Tocris, Cat. # 4423 and 4192, respectively). The cells were grown on 0.1% gelatin-coated dishes and usually seeded at a density of 0.5–1.5 × 104/cm2 ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...
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bioRxiv - Genomics 2022Quote: ... Media was then changed to CM Media supplemented with 2 μM Wnt-C59 (Tocris Biosciences, Bristol, UK) for 2 days prior to switching to CM Media without any supplements ...
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bioRxiv - Neuroscience 2022Quote: ... (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl-cyclopropanecarboxylate-dihydrochloride (NNC550396 or nnc) was purchased from TOCRIS and initially dissolved at 25 mM in water ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2024Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2024Quote: ... neurofibrillary tangles and related AD pathological structures were additionally stained using 1 µM 4,4’-[(2-methoxy-1,4-phenylene) di-(1E)-2,1-ethenediyl] bisphenol (MX-04) (Tocris) for 15 minutes at room temperature ...
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bioRxiv - Cancer Biology 2024Quote: From day 2-7 cells were cultured in SRM media supplemented with 0.1 µM LDN193189 (Tocris Biosciences), 10 µM SB431452(Tocris Biosciences) ...