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501 - 550 of 1510 citations for tert Butyl 3 5 2 amino ethyl thiophen 3 yl propionate since 2020

• Brain capillary obstruction as a novel mechanism of anti-CD19 CAR T cell neurotoxicity

  Lila D Faulhaber, et al., bioRxiv - Neuroscience 2021

  Quote: ... murine IL-2 (Peprotech) (days 1-3 ...
• Long-read sequencing and profiling of RNA-binding proteins reveals the pathogenic mechanism of aberrant splicing of an SCN1A poison exon in epilepsy

  Hannah C Happ, et al., bioRxiv - Genetics 2023

  Quote: ... XAV939 (2 uM, PeproTech), LDN-193189 (100 nM ...
• Commensal bacteria promote type I interferon signaling to maintain immune tolerance

  Adriana Vasquez Ayala, et al., bioRxiv - Immunology 2022

  Quote: ... mouse IL-2 (Peprotech), and human TGF-beta (Peprotech) ...
• deCLUTTER²⁺ pipeline to analyze calcium traces in a novel stem cell model for ventral midbrain patterned astrocytes

  Martyna M. Grochowska, et al., bioRxiv - Neuroscience 2022

  Quote: ... and FGF-2 (Peprotech). The medium was refreshed every other day ...
• The CIpP activator, TR-57, is highly effective as a single agent and in combination with venetoclax against CLL cells in vitro

  Narjis Fatima, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 200 U/ml interleukin 2 (IL-2; Peprotech, Rocky Hill, NJ, USA) for 4 days ...
• Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson’s disease model with Lewy-like pathology

  Christina Paschou, et al., bioRxiv - Neuroscience 2024

  Quote: ... 20 ng/ml fibroblast growth factor-2 (FGF-2; Peprotech, Cranbury, NJ, USA), and 20 ng/ml epidermal growth factor (EGF ...
• A non-invasive method to generate induced pluripotent stem cells from primate urine

  Johanna Geuder, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL PDGF-AB (PeproTech) and 5 ng/mL EGF (Miltenyi Biotec) ...
• The Goldilocks Principle conferred by LDH isoenzymes controls murine T cell glycolysis and differentiation

  Xuyong Chen, Lingling Liu, Ruoning Wang, bioRxiv - Immunology 2022

  Quote: ... mIL-12 (5 ng/mL, PeproTech) (TH1 differentiation) ...
• Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

  Valentina Stolz, et al., bioRxiv - Immunology 2022

  Quote: ... + 5 ng/mL TGF-b (PeproTech), stimulated with anti-CD3/anti-CD28 coated dynabeads (beads ...
• Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics

  Alba Rodriguez-Meira, et al., bioRxiv - Cancer Biology 2022

  Quote: ... GM-CSF (5 ng/mL, Peprotech), IL-3 (10 ng/mL ...
• Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

  Xuyong Chen, et al., bioRxiv - Immunology 2021

  Quote: ... mIL-12 (5 ng/mL, PeproTech) for TH1 differentiation ...
• CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary cells

  Mitchell G. Kluesner, et al., bioRxiv - Bioengineering 2020

  Quote: ... IL-7 (5 ng/mL, PeproTech), and IL-15 (5 ng/mL ...
• T-cell Abca1 and Abcg1 cholesterol efflux pathways suppress T-cell apoptosis and senescence and increase atherosclerosis in middle-aged Ldlr^-/- mice

  Venetia Bazioti, et al., bioRxiv - Immunology 2022

  Quote: ... and 5 ng/mL TGFβ1 (Peprotech) in RPMI 1640 medium supplemented with 10% FCS ...
• Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis

  Rosemarie Ungricht, et al., bioRxiv - Cell Biology 2021

  Quote: ... + 5 ng/ml human Noggin (Peprotech) with a medium change after 2 days ...
• Behavioral-transcriptomic landscape of engineered T cells targeting human cancer organoids

  Johanna F. Dekkers, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 5 nM Heregulin β-1 (Peprotech), 500 nM A83-01 (Tocris) ...
• Fam72a controls the balance between error-prone and error-free DNA repair during antibody diversification

  Mélanie Rogier, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (5 ng/ml; Peprotech) and an anti-CD40 antibody (200 ng/ml ...
• Fam72a controls the balance between error-prone and error-free DNA repair during antibody diversification

  Mélanie Rogier, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (5 ng/ml; Peprotech) and an anti-CD40 antibody (200 ng/ml ...
• Fam72a controls the balance between error-prone and error-free DNA repair during antibody diversification

  Mélanie Rogier, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (5 ng/ml; Peprotech) and an anti-CD40 antibody (200 ng/ml ...
• Modeling Human Spine-Spinal Cord Organogenesis by hPSC-Derived Neuromesodermal Progenitors

  Dairui Li, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 5 ng/ml TGFβ1 (Peprotech) for 48 hours (day 0-day 2) ...
• Distinct eosinophil subsets are modulated by agonists of the commensal-metabolite and vitamin B3 receptor GPR109A during allergic-type inflammation

  Rossana Azzoni, et al., bioRxiv - Immunology 2022

  Quote: ... GM-CSF and IL-5 (Peprotech) in the presence or absence of niacin for 24 hours ...
• NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

  Camille R. Simoneau, et al., bioRxiv - Microbiology 2022

  Quote: ... 5 nM Herefulin beta-1 (Peprotech), and 100 µg/mL of Primocin (InvivoGen) ...
• Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

  Nazir M. Khan, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 5 ng/ml rhbFGF (Peprotech). After 2-3 passage onto non-coated plates ...
• Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

  Daniel Chen, et al., bioRxiv - Neuroscience 2024

  Quote: ... and Y-27632 (Peprotech; 5 uM). On day 7 ...
• Phage DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR/Cas9 editing

  Qiaoyan Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL IL-15 (PeproTech), and 200 U/mL IL-2 (PeproTech) ...
• Phage DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR/Cas9 editing

  Qiaoyan Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL IL-7 (PeproTech), 5 ng/mL IL-15 (PeproTech) ...
• Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment

  Ryusuke Hatae, et al., bioRxiv - Immunology 2023

  Quote: ... IL-7 (Peprotech, 5 ng/ml), and IL-15 (Peprotech ...
• Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis

  Tiago Carvalheiro, et al., bioRxiv - Immunology 2023

  Quote: ... recombinant CXCL4 (5 µg/mL, Peprotech) or the combination of both in DMEM containing 2% FBS and 50 μg/ml of L-ascorbic acid (Wako Pure Chemical) ...
• A conserved role of hnRNPL in regulating alternative splicing of transcriptional regulators necessary for B cell activation

  Poorani Ganesh Subramani, et al., bioRxiv - Immunology 2023

  Quote: ... + IL-4 (5 ng/mL, PeproTech). Alternatively ...
• Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration

  Celina Tretter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 5 ng/mL IL-15 (Peprotech), 30 U/mL IL-2 (Peprotech ...
• Deficiency of ZC3HC1 modulates vascular smooth muscle cell phenotype and increases neointima formation

  Redouane Aherrahrou, et al., bioRxiv - Genetics 2023

  Quote: ... 5 ng/mL PDGF-BB (Peprotech) was added ...
• Live cell imaging of ATP levels reveals metabolic compartmentalization within motoneurons and early metabolic changes in FUS ALS motoneurons.

  Vitaly Zimyanin, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 5 ng/ml FGF2 (Peprotech). Infected fibroblasts were plated onto matrigel coated plates at a density of 10,000 cells per 1w/6w in fibroblast media containing 1 mM VPA an incubated for 48h ...
• Cancer associated fibroblasts mitigate the efficacy of the combination of chemotherapy and BCL-xL targeting in triple negative breast cancer cells

  Lisa Nocquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 5⍰nM Heregulin β-1 (Peprotech), 500⍰nM A83-01 (Tocris) ...
• Synthetic enhancers reveal design principles of cell state specific regulatory elements in hematopoiesis

  Robert Frömel, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Il-5 (10 ng/ml) (Peprotech) and Il-6 (10 ng/ml ...
• An Efficient Direct Conversion Strategy to Generate Functional Astrocytes from Human Adult Fibroblasts

  Uchit Bhaskar, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/ml EGF-1 (Peprotech), 200ng/ml BMP2 (Peprotech) ...
• Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy

  Jacob Bridge, et al., bioRxiv - Immunology 2024

  Quote: ... 5 ng/mL IL-7 (Peprotech), and 5 ng/mL IL-15 (Peprotech) ...
• Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel

  Anna K Greda, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/ml human CNTF (Peprotech) and 10 ng/ml human BMP4 (Peprotech) ...
• Synergy Between TNFα and Proteostatic Stress Drives Cell Death and Guard Immunity

  Matthew Sonnett, et al., bioRxiv - Immunology 2024

  Quote: ... Mouse TNFα (5 ng/ml, Peprotech), Human TNFα (5 ng/ml ...
• Synergy Between TNFα and Proteostatic Stress Drives Cell Death and Guard Immunity

  Matthew Sonnett, et al., bioRxiv - Immunology 2024

  Quote: ... Human TNFα (5 ng/ml, Peprotech), cycloheximide (CHX ...
• Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis

  Sajad Hamid Ahanger, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/ml of BDNF (PeproTech) and 10 µM ROCK inhibitor Y-27632 (Selleckchem)) ...
• Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

  Michael P. East, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5 ng/ml FGF-7 (PEPROTECH), 20 ng/ml FGF10 (PEPROTECH) ...
• Active foam dynamics of tissue spheroid fusion

  Steven Ongenae, et al., bioRxiv - Biophysics 2024

  Quote: ... 100 ng/mL GDF-5 (PeproTech), 10 ng/mL TGF-β 1 (PeproTech) ...
• Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

  Kaja Nicole Wächtershäuser, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 5 ng/ml FGF-7 (PeproTech), 37.5 ng/ml heregulin-β (PeproTech) ...
• The molecular chronology of mammary epithelial cell fate switching

  Queralt Vallmajo-Martin, et al., bioRxiv - Cell Biology 2024

  Quote: ... Neuregulin (5 nM, Peprotech, 100-03), and mEGF (5 ng/ml ...
• Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

  Kaja Nicole Wächtershäuser, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 5 ng/ml FGF-7 (PeproTech), 37.5 ng/ml heregulin-β (PeproTech) ...
• The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins

  Georg Petkau, et al., bioRxiv - Immunology 2022

  Quote: ... peptide and 20 ng/ml recombinant murine interleukin-2 (IL-2) (PeproTech 212-12) and 2 ng/ml IL-12 (PeproTech 210-12 ...
• ZNF865 Regulates Senescence and Cell Cycle for Applications to Cell Engineering and Gene Therapy

  Hunter Levis, et al., bioRxiv - Bioengineering 2023

  Quote: ... 25mM HEPES) supplemented with fresh 2ng/mL fibroblast growth factor-2 (FGF-2) (Peprotech). Cells were cultured in this medium at 37°C and 5% CO2 in a humidified atmosphere and subcultured to 90% confluency ...
• PTPN1/2 inhibition induces highly functional terminal effector CD8 T cells through autocrine IL-10

  Luis-Alberto Perez-Quintero, et al., bioRxiv - Immunology 2023

  Quote: ... and 20U/ml recombinant murine interleukin 2 (rmIL-2) (Peprotech, cat. number 212-12). For stimulation with the cognate OVA 257-264 peptide (SIINFEKL) ...
• Reprogramming of lactate metabolism is linked to the oncogenesis of the virus-induced leukemia

  Kosuke Toyoda, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ATL55T+ was incubated with recombinant human interleukin 2 (rIL-2, 100 U/ml; PeproTech) because of its dependency ...
• Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens

  Celia Alda Catalinas, et al., bioRxiv - Genomics 2023

  Quote: ... and 15 ng/mL of recombinant human interleukin 2 (IL-2) (Peprotech, 200-02). Cells were kept in a humidified 5% CO2 atmosphere at 37°C.
• Frequent Aneuploidy in Primary Human T Cells Following CRISPR-Cas9 cleavage

  A.D. Nahmad, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 50IU rhIL-2 (Peprotech).