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4701 - 4750 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... HDAC2 (1:100, RRID:AB_365273, #5113P, Cell Signaling Technology), TCF7l2 (1:100 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... HDAC2 (1:1000, RRID:AB_10624871, #5113, Cell Signaling Technology), TLE3 (1:1000 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... TCF7l2 (1:200, RRID:AB_2199826, #2569S, Cell Signaling Technology), P-Smad1/5 (1:200 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... TCF7l2 (1:100, RRID:AB_22199816, #2569S, Cell Signaling Technology), β-catenin (1:200 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH (1:1000, RRID:AB_561053, #2118L, Cell Signaling Technology), and HRP goat anti-rabbit (1:3000 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... β-actin (1:1000, RRID:AB_330288, #4967L, Cell Signaling Technology), GAPDH (1:1000 ...
• Impaired p53-mediated DNA damage response contributes to microcephaly in Nijmegen Breakage Syndrome patient-derived cerebral organoids

  Soraia Martins, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti β-actin (1:4000, Cell Signaling). After washing the blots three times with PBS/ 0,05%Tween20 they were incubated with the appropriate secondary antibody ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit Myc-Tag (1:100; Cell Signaling Technology), SUN1 (1:100 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse Myc-Tag (1:500; Cell Signaling Technology), rabbit Myc-Tag (1:100 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit V5-Tag (1:1,000; Cell Signaling Technology), mouse V5-Tag (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse V5-Tag (1:1,000; Cell Signaling Technology), RRP1B (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-MLC2-S19 (1:100; Cell Signaling Technology), p-FAK Y397 (1:500 for tissue IF ...
• A phosphoregulated RhoGEF feedback loop tunes cortical flow driven amoeboid migration in vivo

  Benjamin Lin, Jonathan Luo, Ruth Lehmann, bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-mNeongreen (1:1000, Cell Signaling-53061), mouse anti-α-tubulin (1:4000 ...
• YAP1-TAZ/TEAD transcriptional networks restrain differentiation downstream of oncogenic Hedgehog-SMO activity

  Yao Yuan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p63 (Cell Signaling; catalog no. 39692S; 1:400), mouse KLF4 (R&D ...
• YAP1-TAZ/TEAD transcriptional networks restrain differentiation downstream of oncogenic Hedgehog-SMO activity

  Yao Yuan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PCNA (Cell Signaling; catalogue no. 13110S; 1:400), p63 (Cell Signaling ...
• ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

  Priyanka Verma, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PARP1 (Cell Signaling mAB#9532, 1:2000 dilution), PARP2 antibody (Active Motif ...
• ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

  Priyanka Verma, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GFP (Cell Signaling mAb#2956, 1:1000 dilution), Rev7 (Invitrogen PA5-49352 ...
• The level of oncogenic Ras controls the malignant transformation of Lkb1 mutant tissue in vivo

  Briana Rackley, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-Ras (Cell Signaling 3965, 1:1000), rabbit anti-phospho Ampk (Thr 172 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... PDGFRα (1:1000; D13C6; 5241; Cell Signaling Technology) (autophosphorylation experiments) ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... PDGFRβ (1:1000; 28E1; 3169; Cell Signaling Technology) (autophosphorylation experiments) ...
• The Transcription Factor Xrp1 is Required for PERK- Mediated Antioxidant Gene Induction in Drosophila

  Brian Brown, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse-anti-HA (1:500, Cell Signaling, 2367S), Alexa Fluor 647 goat anti-mouse (1:500 ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or GAPDH (1:1,000, Cell Signaling Technology #3683). Signal was visualized with secondary HRP-conjugated antibodies (1:5,000 ...
• Eliciting OTUD3/RIPK-Dependent Necroptosis to Prevent Epithelial Ovarian Cancer

  Joshua Johnson, et al., bioRxiv - Cancer Biology 2020

  Quote: ... RIPK1 (Cell Signaling Technology #3493, rabbit, 1:1000). PTEN (Cell Signaling Technology #9559 ...
• Eliciting OTUD3/RIPK-Dependent Necroptosis to Prevent Epithelial Ovarian Cancer

  Joshua Johnson, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PTEN (Cell Signaling Technology #9559, rabbit, 1:1000).
• PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma

  Linda Vidarsdottir, et al., bioRxiv - Cancer Biology 2020

  Quote: ... AKT (Cell Signaling, cat. no. 9272, 1:1,000), phospho-AKT (Cell signaling ...
• Caloric restriction alters lipid metabolism to contribute to tumor growth inhibition

  Evan C. Lien, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HA-tag (Cell Signaling Technology #3724, 1:1000), and Vinculin (Cell Signaling Technology 13901 ...
• Caloric restriction alters lipid metabolism to contribute to tumor growth inhibition

  Evan C. Lien, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and Vinculin (Cell Signaling Technology 13901, 1:1000). The mouse Scd1 antibody (Cell Signaling Technology #2438 ...
• Differential RNA editing between epithelial and mesenchymal tumors impacts mRNA abundance in immune response pathways

  Tracey Chan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Vimentin antibody (Cell Signaling Technology, 5741, 1:1000), NF90(ILF3 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or phospho-mTOR (1:100, Cell Signaling, 2971) primary antibody overnight at 4°C ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... E-cadherin (Cell Signaling Technology #3195S, 1:200), phospho-MET (Cell Signaling Technology ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... phospho-MET (Cell Signaling Technology, #3077, 1:50), were incubated with deparaffinized sections at 4°C overnight ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... phospho-Chk2 (Thr68, Cell Signaling #2197, 1:1000), phospho-ATM (Ser1981 ...
• The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

  Anirban Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p65 (1:500; Cell Signaling Technology, # 8242), anti-p100/p52 (1:500 ...
• The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

  Anirban Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-IRE1α (1:500; Cell Signaling Technology, #3294), anti-sXBP-1 (1:1000 ...
• AMPK promotes Arf6 activation in a kinase-independent manner upon energy deprivation

  Kuan-Jung Chen, Jia-Wei Hsu, Fang-Jen S. Lee, bioRxiv - Cell Biology 2021

  Quote: ... anti-AMPK-P (1:1,000, 2535S; Cell Signaling), anti-myc (1:1,000 ...
• Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models

  Vinita G. Chittoor-Vinod, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-AMPK (1:1000; Cell Signaling Technology, 2535); AMPK (1:500 ...
• Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models

  Vinita G. Chittoor-Vinod, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-4EBP (1:750; Cell Signaling Technology, 2855); Non-p-4EBP (1:1000 ...
• RanBP2/Nup358 enhances miRNA activity by sumoylating and stabilizing Argonaute 1

  Qingtang Shen, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Dicer (rabbit polyclonal, 1:1000 dilution, Cell Signaling). Subsequently ...
• Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

  Søs Skovsø, et al., bioRxiv - Physiology 2021

  Quote: ... anti-glucagon (1:100 Cell Signaling Technologies, #2760S), anti-BrdU (1:250 ...
• S-nitrosoglutathione reductase deficiency causes aberrant placental S-nitrosylation and preeclampsia

  Shathiyah Kulandavelu, et al., bioRxiv - Physiology 2021

  Quote: ... VEGFR2 (55B11, 1:1000;Cell Signaling, Danvers, MA), eNOS (1:1000 ...
• ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

  Anne Fougerat, et al., bioRxiv - Physiology 2021

  Quote: ... and anti-Hsp90 (1:1,000, Cell Signaling, #4877) overnight at 4 °C ...
• Identification of proximal SUMO-dependent interactors using SUMO-ID

  Orhi Barroso-Gomila, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-alpha-Actinin (1/5000) (Cell Signaling Technology); anti-Flag (1/1000) ...
• Generation of an Unbiased Interactome for the Tetratricopeptide Repeat Domain of O-GlcNAc Transferase Indicates a Role for the Enzyme in Intellectual Disability

  Hannah M. Stephen, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-αtubulin (WB 1:5000, Cell Signaling 3873) Histone H3 (1:1000 ...
• Hypoxia-inducible lipid droplet-associated interacts with DGAT1 and promotes lipid storage in hepatocytes

  Montserrat A. de la Rosa Rodriguez, et al., bioRxiv - Biochemistry 2020

  Quote: ... or HSP90 (1:5000, Cell Signaling Technology, #4874). Membranes were incubated with a secondary antibody (Anti-rabbit IgG ...
• Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport

  Xiaojian Shi, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-Calreticulin (Cell Signaling Technology, 12238T, 1:1000); Anti-LAMP2 (Santa Cruz Biotechnology ...
• Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport

  Xiaojian Shi, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-VDAC (Cell Signaling Technology, 4661T, 1:1000); Anti-SHMT2 (Sigma-Aldrich ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Rab5a (Cell Signaling, 3547; 1:1,000), mouse anti-GM130 (BD Biosciences ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-ALIX (Cell Signaling, 2171; 1:1,000), mouse anti-CD9 (Sigma-Aldrich ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-LAMP1 (Cell Signaling, 9091; 1:1,000), rabbit anti-Rab7a (Cell Signaling ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Rab7a (Cell Signaling, 9367; 1:1,000), rabbit anti-Rab5a (Cell Signaling ...