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4451 - 4500 of 10000+ citations for 6 Methyl 1 2 4 triazolo 4 3 b pyridazine since 2019

• A CellAgeClock for expedited discovery of anti-ageing compounds

  Celia Lujan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... pS6K (Cell Signaling Technology; 1:1000; 9206S), total S6K (Santa Cruz ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (Cell Signaling Technologies; 9722S; 1:500), G3BP1 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... VPS35 (Cell Signaling Technologies; 81453S; 1:500), eIF2α (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (Cell Signaling Technologies; 9722S; 1:500), G3BP1 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... GAPDH (Cell Signaling Technologies; 2118; 1:10,000), and H3 (Millipore ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... VPS35 (Cell Signaling Technologies; 81453S; 1:1000), eIF2α (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... UPF1 (Cell Signaling Technologies; 12040S; 1:1000), MOV10 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... PABP1 (Cell Signaling Technologies; 4992S; 1:1000), CLTA (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... PABP1 (Cell Signaling Technologies; 4992S; 1:500), CLTA (Proteintech ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... pan-ACTIN (1:1000, Cell Signaling Technology, Cat# 8456 ...
• S-Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Cardiac Hypertrophy

  Matthew J. Brody, et al., bioRxiv - Molecular Biology 2021

  Quote: ... PAK1 (Cell Signaling Technology, #2602, 1:500), H-Ras (Santa Cruz Biotechnology ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 ubiquitin (Cell Signaling Technologies, 3393S); 1/1000 K48-linked polyubiquitin (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 Atf4 (Cell Signaling Technologies, 11815); 1/1000 ubiquitin (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 eif2a (Cell Signaling Technologies, 9722) 1/3000 puromycin (Millipore Simga MABE343) ...
• The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle

  Dina Aweida, Shenhav Cohen, bioRxiv - Cell Biology 2022

  Quote: ... calpain-1 (for immunoblotting) from Cell Signaling, anti-phospho-Threonine/Serine from ECM Biosciences ...
• Prom1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium

  Carlos F. H. Serra, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-RBPSUH (Cell Signaling #5313, 1:100), anti-UGRP1 (R&D Systems ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ULK1 (1:200, Cell Signaling); goat anti-ATG14 (1:50 Santa Cruz Biotech.) ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG13 (1:1000, Cell Signaling); rabbit anti-ATG101 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG14 (1:1000, Cell Signaling); rabbit anti-ATG13 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG13 (1:100, Cell Signaling); rabbit anti-ULK1 (1:200 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-FIP200 (1:200, Cell Signaling); rabbit anti-ATG13 (1:100 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG9A (1:1000, Cell Signaling); rabbit anti-ATG14 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG9 (1:100, Cell Signaling); rabbit anti-p62 phS349 (1:100 ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000(Cell Signaling; cat. No. 2360), CHK2 ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (Cell Signaling; cat. No. 2661S), CHK1 ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Stat3 (124H6, 1:1000, Cell Signaling Technology), pStat3 (Y705 ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Mitf (D5G7V, 1:1000, Cell Signaling Technology), Pmel/gp100 (EP4863(2) ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Irf1 (D5E4, 1:1000, Cell Signaling Technology), Tyr (a-PEP7h’ ...
• DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G₀ cells

  Faith C. Fowler, et al., bioRxiv - Molecular Biology 2021

  Quote: ... KU70 (Cell Signaling Technology, #4588, 1:1000).
• tiRNA-Val promotes angiogenesis via Sirt1–Hif-1α axis in mice with diabetic retinopathy

  Yan Xu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Sirt1 (1:1,000,Cell Signaling Technology, USA), and Hif-1α (1:1,000,Cell Signaling Technology ...
• Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

  Shixiang Guo, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-Wee1 (1:500) (Cell Signaling Technologies), anti-Chk1 (1:500 ...
• Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

  Shixiang Guo, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-Chk1 (1:500) (Cell Signaling Technologies), anti-Cdc2 (1:500 ...
• Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

  Shixiang Guo, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-Cdc2 (1:500) (Cell Signaling Technologies), anti-p27 (1:500 ...
• Transient primary cilia mediate robust Hedgehog pathway-dependent cell cycle control

  Emily K. Ho, Anaïs E. Tsai, Tim Stearns, bioRxiv - Cell Biology 2019

  Quote: ... clone D20B12 (1:1000, Cell Signaling, RRID:AB_11178658), mouse IgG1 anti-p27Kip ...
• Anti-tumor effects of an Id antagonist with no acquired resistance

  Paulina M. Wojnarowicz, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cyclin D1 (2978, Cell Signaling 1:500). Detection was performed using the Vectastain Elite ABC kit (Vector) ...
• Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

  Laurie Herviou, et al., bioRxiv - Cancer Biology 2019

  Quote: ... rabbit anti-p21 (1:500, Cell signaling), rabbit anti-p53 (1:1000 ...
• Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

  Laurie Herviou, et al., bioRxiv - Cancer Biology 2019

  Quote: ... rabbit anti-p53 (1:1000, Cell Signaling), rabbit anti-SETD8 (1:1000 ...
• Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

  Laurie Herviou, et al., bioRxiv - Cancer Biology 2019

  Quote: ... rabbit anti-SETD8 (1:1000, Cell Signaling), mouse anti-β-actin (1:20000 ...
• PI16 is a non-neuronal regulator of neuropathic pain

  Pooja Singhmar, et al., bioRxiv - Neuroscience 2019

  Quote: ... a-Tubulin (1:2000, Cell Signaling 2144S), pMLC2 (Cell Signaling 3674S ...
• Low-dose IFN-γ induces tumor cell stemness in tumor microenvironment of non-small cell lung cancer

  Mengjia Song, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-Notch1 (Cell Signaling Technology, 1:1000), anti-cleaved-Notch1 (Cell Signaling Technology ...
• Low-dose IFN-γ induces tumor cell stemness in tumor microenvironment of non-small cell lung cancer

  Mengjia Song, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-JAK1 (Cell Signaling Technology, 1:1000), anti-phospho-JAK1 (Cell Signaling Technology ...
• Low-dose IFN-γ induces tumor cell stemness in tumor microenvironment of non-small cell lung cancer

  Mengjia Song, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-STAT1 (Cell Signaling Technology, 1:1000), anti-phospho-STAT1 (Cell Signaling Technology ...
• Low-dose IFN-γ induces tumor cell stemness in tumor microenvironment of non-small cell lung cancer

  Mengjia Song, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-caspase3 (Cell Signaling Technology, 1:1000), anti-cleaved-caspase3 (Cell Signaling Technology ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... Phospho S6 (Cell Signaling Technology; 1:1000), S6 (Cell Signaling Technology1:1000) ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... Phospho 4EBP1 (Cell Signaling Technology; 1:1000), 4EBP1 (Cell Signaling Technology ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-rabbit (Cell Signaling Technology; 1:1000), anti-rat (Santa Cruz Biotechnology ...
• Osteocytes remodel bone by TGF-β-induced YAP/TAZ signaling

  Christopher D. Kegelman, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-YAP (1:200, 14074; Cell Signaling), and anti-TAZ (1:200 NB110-58359 ...
• mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation

  Yuqi Zhang, et al., bioRxiv - Cell Biology 2019

  Quote: ... and 1:100 E-cadherin (Cell Signaling), or 1:100 αE-catenin (Genetex (Irvine ...
• Caspase-8 Modulates Angiogenesis By Regulating A Cell Death Independent Pathway In Endothelial Cells

  Nathalie Tisch, et al., bioRxiv - Developmental Biology 2019

  Quote: ... RIPK3 (1:1000, ref.13526, Cell Signaling), Casp-8 (1:1000 ...
• Caspase-8 Modulates Angiogenesis By Regulating A Cell Death Independent Pathway In Endothelial Cells

  Nathalie Tisch, et al., bioRxiv - Developmental Biology 2019

  Quote: ... ERK (1:1000, ref.9102, Cell Signaling), RIPK3 (1:1000 ...