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4351 - 4400 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression

  Xiaofei Zhi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Pdgfra (1:200, Cell Signaling Technology), anti-α-SMA (1:500 ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phosphor-STAT1 (Cell Signaling, 8826S, 1:1000), S6 (Cell Signaling ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phosphor-S6 (Cell Signaling, 4858T, 1:1000), Pol II (Cell Signaling ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Pol II (Cell Signaling, 2629S, 1:1000), and Phosphor-Pol II-Ser2 (Cell Signaling ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Pol II (Cell signaling, 2629S,1:50), phospho-Pol II (cell signaling ...
• Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

  Hans-Georg Sprenger, et al., bioRxiv - Molecular Biology 2024

  Quote: ... GAPDH (1:1000, Cell Signaling, rabbit, #5174) RRID ...
• Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

  Hans-Georg Sprenger, et al., bioRxiv - Molecular Biology 2024

  Quote: ... VDAC (1:1000, Cell Signaling, rabbit, #4661) RRID ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... pSTAT1-S727 (Cell Signaling #8826, 1:1000), STAT1 (Cell Signaling #14994 ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... pSTAT1-Y701 (Cell Signaling #9167, 1:1000), pSTAT1-S727 (Cell Signaling #8826 ...
• E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation

  Vartika Sharma, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Rabbit anti-GAPDH (1:1000, Cell Signaling). Images were obtained with Chemidoc XRS+ (Biorad).
• FMRP regulates tangential neuronal migration via MAP1B

  Salima Messaoudi, et al., bioRxiv - Neuroscience 2023

  Quote: ... Vinculin (Cell Signaling Technology, 13901S, 1/1000). The antibodies were diluted in TBSt containing 5% powder milk ...
• Non-canonical contribution of human Dicer helicase domain in antiviral innate immune response

  Morgane Baldaccini, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-PKR (1:1000, #12297 Cell signaling), anti-p-PKR (1:1000 ...
• PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

  Teruhiko Yoshida, et al., bioRxiv - Pathology 2024

  Quote: ... Stat3 (#9139, 1:1000 dilution, Cell Signaling), β-actin (#47778 ...
• PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

  Teruhiko Yoshida, et al., bioRxiv - Pathology 2024

  Quote: ... VDAC (# 4661, 1:1000 dilution, Cell Signaling). Blots were imaged using the Odyssey infrared scanner (LI-COR ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... AKT (1:100; Cell Signaling Technology, 9272S), PHLPP (1:50 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LAMP1 (1:100, Cell Signaling Technology, 9091S), AKT (1:100 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rheb (1:100, Cell Signaling Technology, 13879S), Raptor (1:100 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TSC1 (1:100, Cell Signaling Technology, 6935S), TSC2 (1:100 ...
• Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells

  Sefora Conti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:100 (Cell Signaling cat. no. 3142), rabbit anti-phospho Ezrin (Thr567)/ Radixin (Thr564)/ Moesin (Thr558) ...
• Lactoylglutathione promotes inflammatory signaling in macrophages

  Marissa N. Trujillo, et al., bioRxiv - Biochemistry 2023

  Quote: ... H3 (1:20,000, Cell Signaling Technologies, #3638S), Actin (1:10,000 ...
• STK25 is an IRF5 kinase that promotes TLR7/8-mediated inflammation

  Matthew R. Rice, et al., bioRxiv - Biochemistry 2023

  Quote: ... and GAPDH (Cell Signaling, 3683, 1:5000) were used as loading controls for protein normalization ...
• Sequentially activated death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling

  Ronit Schwartz Wertman, et al., bioRxiv - Immunology 2023

  Quote: ... cleaved-caspase-8 (Cell signaling, 1:1000) GSDMD (Abcam ...
• Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

  Yannick Perez, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-histone H4 (1:1000, Cell Signaling), anti-H4K20me states (1:1000 ...
• Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

  Yannick Perez, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-histone H3 (1:5000, Cell Signaling), anti-histone H4 (1:1000 ...
• Modeling aging and retinal degeneration with mitochondrial DNA mutation burden

  John Sturgis, et al., bioRxiv - Cell Biology 2023

  Quote: ... β- actin (Cell Signaling, 8H10D10 1:5000), Tubulin (Cell Signaling ...
• Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

  Michelle E. Watts, et al., bioRxiv - Cell Biology 2023

  Quote: ... CHOP (Cell Signaling Technology 2895T, 1:1000), Cleaved Caspase-3 (Cell Signaling Technology 9664S ...
• Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

  Michelle E. Watts, et al., bioRxiv - Cell Biology 2023

  Quote: ... eIF2α (Cell Signaling Technology 9722S, 1:1000), GRP78 BiP (Abcam ab21685 ...
• ZO-1 regulates Hippo-independent YAP activity and cell proliferation via a GEF-H1- and TBK1-regulated mechanosensitive signalling network

  Alexis J. Haas, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit polyconal (95777, Lot 1, Cell Signaling); Ki67 ...
• Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits

  Haibin Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... FLAG (1:3000, Cell Signaling Technology, 14793). For the Western blot experiment in Figure S2C and D ...
• Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits

  Haibin Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... HA (1:3000, Cell Signaling Technology, 3724), Tubulin (1:3000 ...
• Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits

  Haibin Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Tubulin (1:3000, Cell Signaling Technology, 12351S), FLAG (1:3000 ...
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... or JAK3 (1:500, Cell Signaling, 8863S). Horseradish peroxidase-conjugated β-actin (1:500 ...
• Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration

  Natalie A. David, et al., bioRxiv - Immunology 2023

  Quote: ... NCOR1 (Cell Signaling Technology 5948; 1:100), donkey anti-rabbit IgG (eBioscience 12-4739-81 ...
• Hallmark molecular and pathological features of POLG disease are recapitulated in cerebral organoids

  Anbin Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... NeuN (rabbit, 1:500; Cell Signaling, #24307S), MAP2 (rabbit ...
• Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity

  Sudershana Nair, Nicholas E. Baker, bioRxiv - Developmental Biology 2023

  Quote: ... anti-Dcp1 (rabbit, 1:100, Cell Signaling), anti-Sens (guinea pig ...
• Microtubule association of TRIM3 revealed by differential extraction proteomics

  Hannah L. Glover, et al., bioRxiv - Cell Biology 2023

  Quote: ... EML4 (Cell Signaling Technology, 12156S, 1:1000), GAPDH (Cell Signalling Technology ...
• Loss of FBXO11 function establishes a stem cell program in acute myeloid leukemia through dysregulation of mitochondrial LONP1

  Angela Ya-Chi Mo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... HSP60 1:1000 (Cell Signaling Technology 4870S), LONP1 antibody at 1:1000 (ThermoFisher Scientific 15440-1-AP) ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TSC2 (1:100; Cell Signaling Technology, 4308S), Rheb (1:100 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mTOR (1:100; Cell Signaling Technology, 2983S), TSC1 (1:100 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Raptor (1:100; Cell Signaling Technology, 2290S), Rictor (1:100 ...
• A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

  Oriana Y. Teran Pumar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rictor (1:100; Cell Signaling Technology, 2114S), LAMP1 (1:100 ...
• Early Deficits in Dentate Circuit and Behavioral Pattern Separation after Concussive Brain Injury

  Lucas Corrubia, et al., bioRxiv - Neuroscience 2023

  Quote: ... or PV antibody (1:500, Cell Signaling D3S8R ...
• Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

  Laura F. Mattner, et al., bioRxiv - Systems Biology 2023

  Quote: ... HRP-linked (1:20,000, Cell Signaling #7074) Anti-mouse IgG ...
• Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

  Laura F. Mattner, et al., bioRxiv - Systems Biology 2023

  Quote: ... HRP-linked (1:20,000, Cell Signaling #7074). Images were quantified in the Image Lab software (Biorad) ...
• Tumor cell-adipocyte gap junctions activate lipolysis in breast cancer

  Roman Camarda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pHSL S563 (4139, Cell Signaling, 1:1000), HSL (4107 ...
• Short-term molecular consequences of chromosome mis-segregation for genome stability

  Lorenza Garribba, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (1:2000, #2118, Cell Signaling Technology) and vinculin (1:5000 ...
• The autism-associated loss of δ-catenin functions disrupts social behaviors

  Hadassah Mendez-Vazquez, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-pGSK3β (Cell Signaling Technology, 1:1000), and anti-actin (Abcam ...
• H3.1^Cys96 oxidation by mitochondrial ROS promotes chromatin remodeling, breast cancer progression to metastasis and multi-drug resistance

  Flavio R. Palma, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Fibronectin (1:1000, Cell Signaling Technology, #26836) and GAPDH (1:1000 ...
• A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation

  Katherine J. Susa, et al., bioRxiv - Immunology 2023

  Quote: ... EAAT3 antibody (Cell Signaling, 1:1000 dilution), SWAP70 antibody (Cell Signaling ...
• Propionate reinforces epithelial identity and reduces aggressiveness of non-small cell lung carcinoma via chromatin remodelling

  Vignesh Ramesh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... γH2AX (1:2000, rabbit, Cell Signaling, 9718S), GRHL1 (1:1000 ...