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4151 - 4200 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Drug dependence in cancer is exploitable by optimally constructed treatment holidays

  Jeff Maltas, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK (1:1000, #4695 Cell Signaling Technology), EGFR (1:1000 ...
• Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates

  Donghwi Bae, et al., bioRxiv - Cell Biology 2022

  Quote: ... alpha-TUBULIN (Cell Signaling 2144, 1:25), LAMP (DSHB ...
• Succinate mediates inflammation-induced adrenocortical dysfunction

  Ivona Mateska, et al., bioRxiv - Immunology 2022

  Quote: ... anti-DNMT1 (1:1000; Cell Signaling, #5032) or anti-Tubulin (1:3000 ...
• Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

  Ben Vanderkruk, et al., bioRxiv - Cell Biology 2022

  Quote: ... H3K27ac (Cell Signaling Technologies, D5E4, 1:1,000), H3K27me3 (Millipore ...
• Deconvoluting signals downstream of growth and immune receptor kinases by phosphocodes of the BSU1 family phosphatases

  Chan Ho Park, et al., bioRxiv - Plant Biology 2022

  Quote: ... anti-Myc (Cell Signaling; 1:3,000 dilution), anti-HA (Roche ...
• An Aurora B-RPA signaling axis secures chromosome segregation fidelity

  Poonam Roshan, et al., bioRxiv - Biochemistry 2022

  Quote: ... Histone H3 (1:2000; Cell Signaling, 14269). All phospho-specific primary antibodies were diluted (1:1000 ...
• Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling

  David M. Walter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mTOR (Cell Signaling Technology, cs2983, 1:100), LAMP2 (Abcam ...
• The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin

  Colin Stok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin B1 (Cell Signaling, 68591, 1:1000), Histone H3 (Abcam ...
• Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

  Christina Plattner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-mTOR (Cell Signaling, #5536T, 1:2000), phospho-AKT (Cell Signaling ...
• An in vivo avian model of human melanoma to perform rapid and robust preclinical studies

  Loraine Jarrosson, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-SOX10 (1/200, 89356, Cell Signaling) were applied to cryosections and incubated overnight at 4°C ...
• Single cell spatial analysis identifies regulators of brain tumor initiating cells

  Reza Mirzaei, et al., bioRxiv - Cancer Biology 2022

  Quote: ... β-catenin (1:3000; Cell Signaling Technology, 37447S) diluted in Blocking Buffer were incubated overnight at 4°C ...
• Single cell spatial analysis identifies regulators of brain tumor initiating cells

  Reza Mirzaei, et al., bioRxiv - Cancer Biology 2022

  Quote: ... β-catenin (1:800; Cell Signaling Technology, 37447S) and CD44 (1:500 ...
• Toxicity of microplastics and plastic additive co-exposure in liver Disse organoids from healthy donors and patient-derived induced pluripotent stem cells

  Shaojun Liang, et al., bioRxiv - Bioengineering 2022

  Quote: ... COL1A1 (1:100, Cell Signaling Technology, 72026), F-actin (Invitrogen ...
• Toxicity of microplastics and plastic additive co-exposure in liver Disse organoids from healthy donors and patient-derived induced pluripotent stem cells

  Shaojun Liang, et al., bioRxiv - Bioengineering 2022

  Quote: ... CD31 (1:100, Cell Signaling Technology, 89C2), MRP2 (1:100 ...
• A genetically encoded tool to increase cellular NADH/NAD⁺ ratio in living cells

  Mina L. Heacock, et al., bioRxiv - Bioengineering 2022

  Quote: ... anti-HSP60 (Cell Signaling, #12165; 1:2000). Alexa Fluor 488- and Alexa Fluor 568-conjugated secondary antibodies were used (ThermoFisher ...
• Control of cell proliferation by memories of mitosis

  Franz Meitinger, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p21 (1:1,000; #2947; Cell Signaling Technology), anti-α-tubulin (1:5,000 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... HA (1:1000, 6E2, #2367, Cell Signaling), H2A (1:1000 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... HDAC1 (1:100, D5C6U, #34589, Cell Signaling), HP1 (1:200 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... H3K9me3 (1:500, D4W1U, #13969, Cell Signaling), FLAG (1:500 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... HA (1:500, C29F4, #3724, Cell Signaling), HA (1:100 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... HA (1:1000, C29F4, #3724, Cell Signaling), HA (1:1000 ...
• ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo

  Alison Boutet, Carlos Zeledon, Gregory Emery, bioRxiv - Cell Biology 2022

  Quote: ... anti-pERM (3141S, Cell Signaling, 1:100), anti-Fasciclin III (7G10 ...
• ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature

  Masaya Yamazaki, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or BRD4 (Cell Signaling Technology; 1:100). Antibody/antigen complexes were recovered with Dynabeads M-280 sheep anti-rabbit IgG (Thermo Fisher Scientific ...
• USP10 strikes down Wnt/β-catenin signaling by dual-wielding deubiquitinase activity and phase transition potential

  Yinuo Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... Ki67 (1:400, #9449, Cell Signaling Technology). The staining was examined using HRP Envision Systems (DAB Kit ...
• STIM1 signals through NFAT independently of Orai1 and SOCE to regulate breast cancer cell migration

  Ayat S. Hammad, et al., bioRxiv - Cell Biology 2022

  Quote: ... STIM2 (Cell Signaling Technology #4917, 1:1000), β-actin (C4 ...
• Salinomycin disturbs Golgi apparatus function and specifically affects cells in epithelial-to-mesenchymal transition

  Marko Marjanović, et al., bioRxiv - Cancer Biology 2022

  Quote: ... eIF2α (1:1000, Cell Signaling Technology, 9722), p-eIF2α (1:1000 ...
• Salinomycin disturbs Golgi apparatus function and specifically affects cells in epithelial-to-mesenchymal transition

  Marko Marjanović, et al., bioRxiv - Cancer Biology 2022

  Quote: ... EGFR (1:1000, Cell Signaling Technology, 4267), TFRC (1:500 ...
• Spatial analysis of the metastatic brain tumor immune and extracellular matrix microenvironment

  Samuel S. Widodo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD163 (Cell Signaling Technology #93498, 1:250), CD206 (Abcam ab64693 ...
• H3K36M provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis

  Eun Kyung Ko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti- H3K27me3 (Cell Signaling, #9733S, 1:400), anti-Ki-67 (Abcam ...
• Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors

  Katsuhiro Tomofuji, et al., bioRxiv - Cell Biology 2022

  Quote: ... HRP-linked (Cell Signaling, 7076, 1:3000).
• Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors

  Katsuhiro Tomofuji, et al., bioRxiv - Cell Biology 2022

  Quote: ... HRP-linked (Cell Signaling, 7074, 1:3000), and horse anti-mouse IgG ...
• A tissue injury repair pathway distinct but parallel to host pathogen defense

  Siqi Liu, et al., bioRxiv - Immunology 2022

  Quote: ... p-STAT3 (D3A7, Cell Signaling 1:1000), LDHA (21799-1-AP ...
• Never in Mitosis Kinase 2 regulation of metabolism is required for neural differentiation

  Danielle M. Spice, et al., bioRxiv - Developmental Biology 2022

  Quote: ... TOM20 (1:1000; Cell Signaling Technology, 42406), HIF1α (ab179483 ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... HSL (1:2000, Cell signaling, Cat#4107), HSL-pS660 (1:1000 ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... AKT (1:1000; Cell signaling, Cat#4685), AKT-pS473 (1:1000 ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... GAP43 (1:1000, Cell signaling, Cat#8945), GAP43-pS41 (1:1000 ...
• Modulation of the extracellular matrix by Streptococcus gallolyticus subsp. gallolyticus and importance in cell proliferation

  Ritesh Kumar, et al., bioRxiv - Microbiology 2022

  Quote: ... β-catenin (1:4000, Cell Signaling Technology (CST)) ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... TIAR (1:1000; rabbit, Cell Signaling, #8509). For band visualization ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... GFP (1:1000; rabbit, Cell Signaling, #2956); HA tag (1:1,000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... eIF4G (1:1000; rabbit, Cell Signaling, #2498); G3BP1 (1:4000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... eIF2α (1:1000; rabbit, Cell Signaling, #5324); eIF4G (1:1000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... TIAR (1:1000; rabbit, Cell Signaling, #8509). Alexa Fluor (AF)-conjugated secondary antibodies used were ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Dicer (1:1000) (Cell Signaling #D38E7), anti-Drosha (1:1000 ...
• Nuclear m6A Reader YTHDC1 Promotes Muscle Stem Cell Activation/Proliferation by Regulating mRNA Splicing and Nuclear Export

  Yulong Qiao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... hnRNPG (Cell Signaling Technology, #14794, 1:1000), Histone H3 (Santa Cruz ...
• Nuclear m6A Reader YTHDC1 Promotes Muscle Stem Cell Activation/Proliferation by Regulating mRNA Splicing and Nuclear Export

  Yulong Qiao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... YTHDC1 (Cell Signaling Technology, #77422, 1:1000), MyoD (Abclonal ...
• Fibronectin-integrin α5 signaling promotes thoracic aortic aneurysm in a mouse model of Marfan syndrome

  Minghao Chen, et al., bioRxiv - Pathology 2022

  Quote: ... total-p65 (1:500, 4764s, Cell Signaling), CD45 (1:500 ...
• The RSK-RPS6 Axis Controls the Preconditioning Effect and Induces Spinal Cord Regeneration

  Charlotte Decourt, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-RPS6 (1/1000, Cell Signaling Technology), anti-phospho-RPS6 ser235/236 (1/1000 ...
• The RSK-RPS6 Axis Controls the Preconditioning Effect and Induces Spinal Cord Regeneration

  Charlotte Decourt, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-RSK2 (1/100, Cell Signaling Technology), anti-RPS6 (1/100 ...
• The RSK-RPS6 Axis Controls the Preconditioning Effect and Induces Spinal Cord Regeneration

  Charlotte Decourt, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-RPS6 (1/100, Cell Signaling Technology), anti-phospho-RPS6 ser235/236 (1/100 ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 2331, WB 1:1,000); rabbit anti-GST-Tag ...