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4051 - 4100 of 10000+ citations for 6 METHYL 4 4 NITRO PHENYL 2 OXO 1 2 3 4 TETRAHYDRO PYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER since 2019

• Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

  Minchul Kim, Yao Zhang, Carmen Birchmeier, bioRxiv - Cell Biology 2020

  Quote: ... AMPKα (Cell Signaling 2532, 1:1000), phospho-AMPKα (Cell Signaling 2531 ...
• Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

  Minchul Kim, Yao Zhang, Carmen Birchmeier, bioRxiv - Cell Biology 2020

  Quote: ... S6K (Cell Signaling 2708, 1:1000), phospho-S6K (Cell Signaling 97596 ...
• Transcriptional Control of Brain Tumour Stem Cells by a Carbohydrate Binding Protein

  Ahmad Sharanek, et al., bioRxiv - Cancer Biology 2021

  Quote: ... STAT3 (1:1000, Cell Signaling, #9139), phospho-STAT3 (Tyr705 ...
• Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

  MA Jiajia, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:100 (#4370, Cell Signaling Technology), Rabbit anti-p44/42 MAPK (Erk1/2) ...
• Counteracting Genome Instability by p53-dependent Mintosis

  Jianqing Liang, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-γH2AX (1:200; Cell Signaling; #9718 for IF ...
• Cell-to-cell heterogeneities during extrinsic apoptosis arise from cell cycle progression and transmitotic apoptosis resistance

  Nadine Pollak, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Mcl-1 (Cell Signaling), mouse anti-PARP (BD Biosciences) ...
• ERK signaling licenses SKN-1A/NRF1 for proteasome production and proteasomal stress resistance

  Peng Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... CAS3 (Cell Signaling Technology; 1:1,000), Actin (1:1,000) ...
• Molecular mechanisms underlying attenuation of live attenuated Japanese encephalitis virus vaccine SA14-14-2

  Pooja Hoovina Venkatesh, et al., bioRxiv - Cell Biology 2021

  Quote: ... Beclin-1 (Cell Signaling Technology #3738), IRE-1α (Novus Biologicals #NB100-2323) ...
• Wilms Tumorigenesis in Human Kidney Organoids

  Verena Waehle, et al., bioRxiv - Cancer Biology 2021

  Quote: ... LIN28B (Cell Signaling #4196, 1:250); NPHS1 (R&D Systems #AF4269 ...
• Wilms Tumorigenesis in Human Kidney Organoids

  Verena Waehle, et al., bioRxiv - Cancer Biology 2021

  Quote: ... LIN28A (Cell Signaling #3978, 1:600); LIN28B (Cell Signaling #4196 ...
• Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity

  Irene Riera-Tur, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-beclin-1 (3495, Cell Signaling), anti-HPRT (ab10479 ...
• Sex-Specific Role of Myostatin Signaling in Neonatal Muscle Growth, Denervation Atrophy, and Neuromuscular Contractures

  Marianne E Emmert, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GAPDH (1:5000; Cell Signaling #2118) served as a control for sample loading ...
• History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2022

  Quote: ... total Akt (1:1000, Cell Signaling), total ERα (1:1000 ...
• In vivo reprogramming leads to premature death due to hepatic and intestinal failure

  Alberto Parras, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Asp175 (1:200, Cell Signaling, 9661).
• Genetic control of neuronal activity enhances axonal growth only on permissive substrates

  Francina Mesquida-Veny, et al., bioRxiv - Neuroscience 2022

  Quote: ... c-Fos (1:200, Cell Signaling), ChR2 (1:500 ...
• Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice

  Stephen C. Gironda, et al., bioRxiv - Neuroscience 2022

  Quote: ... BACE1 (Cell Signaling; 5606S; 1:1000), ADAM10 (Millipore ...
• Sex-Specific Role of Myostatin Signaling in Neonatal Muscle Growth, Denervation Atrophy, and Neuromuscular Contractures

  Marianne E Emmert, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GAPDH (1:5000; Cell Signaling #2118) served as a control for sample loading ...
• Impairments in SHMT2 expression or cellular folate availability reduce oxidative phosphorylation and pyruvate kinase activity

  Joanna L. Fiddler, et al., bioRxiv - Biochemistry 2022

  Quote: ... and GAPDH (Cell Signaling, 1:2000) were used ...
• Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice

  Stephen C. Gironda, et al., bioRxiv - Neuroscience 2022

  Quote: ... GluN2B (Cell Signaling; 4212; 1:1000), GABAAR α5 (Santa Cruz ...
• Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice

  Stephen C. Gironda, et al., bioRxiv - Neuroscience 2022

  Quote: ... GluN2A (Cell Signaling; 4025; 1:1000), GluN2B (Cell Signaling ...
• Spt6 directly interacts with Cdc73 and is required for Paf1C recruitment to active genes

  Mitchell A. Ellison, et al., bioRxiv - Molecular Biology 2022

  Quote: ... H2BK123ub (Cell Signaling 5546, 1:1,000), HA tag (Roche 11666606001 ...
• Single-Cell Multi-Omic Roadmap of Human Fetal Pancreatic Development

  de la O Sean, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Glucagon (1:200, Cell Signaling, 2760S), Insulin (1:200 ...
• Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome

  Xiaojing Mao, et al., bioRxiv - Developmental Biology 2022

  Quote: ... K18 (1:1000, Cell Signaling #4548), total β-Catenin (1:1000 ...
• Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome

  Xiaojing Mao, et al., bioRxiv - Developmental Biology 2022

  Quote: ... RCC1 (1:1000, Cell Signaling #3589), S6 Ribosomal Protein (1:1000 ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-MYC 1:100 (Cell Signaling) and anti-Hemoglobin 1:1000 (MP Biomedicals) ...
• Plasticity in airway smooth muscle differentiation during mouse lung development

  Katharine Goodwin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... pMLC2 (Cell Signaling 3671, 1:200), RFP (Abcam ab62341 ...
• Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

  Josef Leibold, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MSH2 (1:200, Cell Signaling, D24B5), MYC (1:100 ...
• Single-cell Sequencing Reveals Brain/Spinal Cord Oligodendrocyte Precursor Heterogeneity and Requirement for mTOR in Cholesterol Biosynthesis and Myelin Maintenance

  Luipa Khandker, et al., bioRxiv - Neuroscience 2020

  Quote: ... Hmgcs1 (Cell Signaling, 42201S, 1:1000), Fdps (Proteintech ...
• Single-cell Sequencing Reveals Brain/Spinal Cord Oligodendrocyte Precursor Heterogeneity and Requirement for mTOR in Cholesterol Biosynthesis and Myelin Maintenance

  Luipa Khandker, et al., bioRxiv - Neuroscience 2020

  Quote: ... β-tubulin (Cell Signaling, 5346S, 1:1000), and β-amyloid (Invitrogen ...
• Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

  Laura Sebastian Monasor, et al., bioRxiv - Neuroscience 2019

  Quote: ... CSF1R (1:1000, 3152, Cell Signaling) and FABP5 (1:400 ...
• Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

  Júlia Canet-Pons, et al., bioRxiv - Neuroscience 2019

  Quote: ... RIPK1 (Cell Signaling 3493S, 1:500), TDP43 (Abcam ab41881 ...
• Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

  Júlia Canet-Pons, et al., bioRxiv - Neuroscience 2019

  Quote: ... CASP3 (Cell Signaling 9665, 1:1000), GFAP (Dako ZO334 ...
• Enhanced FGFR3 activity in post-mitotic principal neurons during brain development results in cortical dysplasia and axon miswiring

  Jui-Yen Huang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Draq5 (1:10,000 dilution, Cell Signaling) or 4′,6-diamidino-2-phenylindole (DAPI ...
• Transmission-selective muscle pathology induced by active propagation of mutant huntingtin across the human neuromuscular synapse

  Dinamarca C. Margarita, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:800 V5 (D3H8Q, Cell Signaling), 1:40 NF2H3 (AB2314897 ...
• The fragile X mental retardation protein promotes adjustments in cocaine self-administration that preserve reinforcement level

  Jessica L. Huebschman, et al., bioRxiv - Neuroscience 2020

  Quote: ... NR2B (Cell Signaling 14544S, 1:1000), and GAPDH (Fisher-Scientific AM4300 ...
• EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

  Kai Voeltzke, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MYCN (1:1,000, Cell Signaling #9405), GAPDH (1:1,000 ...
• EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

  Kai Voeltzke, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GAPDH (1:1,000, Cell Signaling #2118), and β-Actin (1:5,000 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... NeuN (1:500, Cell Signaling Technology), Brn3a (1:200 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... NFM (1:1000, Cell Signaling Technology), GFP (1:1000 ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... MUC5AC (1:500) (Cell Signaling Technologies) and MUC5B (1:500 ...
• Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8⁺ T cell-mediated immunopathology

  S. Wali, et al., bioRxiv - Immunology 2020

  Quote: ... and cCasp3 (1:500; Cell Signaling). EdU ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... ULK1 (1:1000; Cell Signaling 8054), p-ULK1 (1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... mTOR (1:1000; Cell Signaling 2972), p-mTOR (1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH (1:1000; Cell Signaling 2118), ULK1 (1:1000 ...
• Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processes

  Annika Bub, et al., bioRxiv - Neuroscience 2021

  Quote: ... NCAM (1:1,000, #99746; Cell Signaling), P2Y12 (1:500 ...
• Extracellular vesicles induce aggressive phenotype of luminal breast cancer cells by PKM2 phosphorylation

  Seo Young Kang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GLUT1 (1:1000; D3J3A; Cell Signaling), PKM2 (1:1000 ...
• Extracellular vesicles induce aggressive phenotype of luminal breast cancer cells by PKM2 phosphorylation

  Seo Young Kang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PKM2 (1:1000; D78A4; Cell Signaling), anti-phospho Y105 PKM2 (1:1000 ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total 4EBP1 (Cell Signaling; 1:1000), pAKT308 (Cell Signaling ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total S6 (Cell Signaling; 1:1000), p4EBP1 (Fluidigm ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total Akt (Cell Signaling; 1:1000), pGSK3ß (Cell Signaling ...