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4001 - 4050 of 10000+ citations for 6 METHYL 4 4 NITRO PHENYL 2 OXO 1 2 3 4 TETRAHYDRO PYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER since 2019

• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... JUN 1:500 (Cell signaling #9165), p-AKT (Cell signaling #9271) ...
• Prenatal Methadone Exposure Disrupts Behavioral Development and Alters Motor Neuron Intrinsic Properties and Local Circuitry

  Gregory G. Grecco, et al., bioRxiv - Neuroscience 2020

  Quote: ... Draq5 (1:10,000 dilution, Cell Signaling) was included in the secondary antibody solution to stain nuclei ...
• A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

  Nikhil Gupta, et al., bioRxiv - Molecular Biology 2021

  Quote: ... α-DNMT3A (Cell Signaling #3598, 1:500), α-DNMT3B (Novus #56514 ...
• APOBEC3A drives acquired resistance to targeted therapies in non-small cell lung cancer

  Hideko Isozaki, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Actin (1:1000, Cell Signaling #4970), γH2AX (1:1000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... H3K27me3 (1:5,000; Cell Signaling Technology), H3K9me3 (1:5,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... H3K27Ac (1:500; Cell Signaling Technology), H3K9me3 (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... EZH2 (1:1,000; Cell Signaling Technology), and SUZ12 (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SUV39H1 (1:1,000, Cell Signaling Technology), EZH2 (1:1,000 ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... JNK (1:1,000, Cell Signaling Technology #9252S or 1:2,000 Santa Cruz Biotechnology sc-7345) ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MKK7 (1:1,000, Cell Signaling Technology #4172S or 1:2,000 ...
• In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets

  Michela Carlet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MCL-1 (Clone D2W9E, Cell signaling) or respective isotype controls (Cat. ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p62 1:1000 (Cell Signaling, 5114), LC3B 1:1000 (D11 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HSP90 1:1000 (Cell Signaling, 4877S), Rheb 1:1000 (E1G1R ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p70S6K1 1:1000 (Cell Signaling, 9202), GAPDH 1:10,000 (14C10 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... SDHA 1:1000 (Cell Signaling, 5839), Tom20 1:100 (F-10 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Akt 1:1000 (Cell Signaling, 9272), Deptor 1:1000 (Novus Bio ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... CDK4 (Cell Signaling #12790, 1:1000), CDK2 (Santa Cruz Biotechnology #sc-6248 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... Parkin (1:1,000, Cell Signaling, Prk8), PINK1 (1:1,000 ...
• Reduced Shmt2 expression impairs mitochondrial folate accumulation and respiration, and leads to uracil accumulation in mouse mitochondrial DNA

  Joanna L. Fiddler, et al., bioRxiv - Biochemistry 2021

  Quote: ... and GAPDH (Cell Signaling, 1:2000) were used ...
• Multiscale profiling of enzyme activity in cancer

  Ava P. Soleimany, et al., bioRxiv - Bioengineering 2021

  Quote: ... PDGFRβ (3169, Cell Signaling, 1: 100), and desmin (ab227651 ...
• The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

  Francesca Boscolo Sesillo, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-SMA (Cell Signaling, 19245S, 1:100), collagen I (Invitrogen ...
• Single cell 3’UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism

  Manuel Göpferich, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH (Cell Signaling, Rabbit, 1:1000), Histone H3 (Cell Signaling ...
• SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice

  Alan T. Tang, et al., bioRxiv - Microbiology 2021

  Quote: ... β-Actin (1:1000; Cell Signaling; 4970).
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... eIF2α 1:500 (Cell signaling #5324), p-eIF2α 1:500 (Cell signaling #3398) ...
• Vorinostat corrects cognitive and non-cognitive symptoms in a mouse model of fragile X syndrome

  Qi Ding, Xueting Wu, Xuan Li, Hongbing Wang, bioRxiv - Neuroscience 2020

  Quote: ... and H4 (Cell Signaling, 1:1000). The relative amount of loading was determined by β-actin ...
• Inhibition of mTOR during a postnatal critical sensitive window rescues deficits in GABAergic PV cell connectivity and social behavior caused by loss of TSC1

  Mayukh Choudhury, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pAMPK (1:800, Cell Signaling), and anti-GAPDH (1:5000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... ULK1 (1:1000, Cell Signaling, #8054), p62 (1:2000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... FIP200 (1:1000, Cell Signaling, #12436), Atg101 (1:1000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atg101 (1:1000, Cell Signaling, #13492), ULK1 (1:1000 ...
• Docosahexaenoic Acid has stem cell-specific effects in the SVZ and restores olfactory neurogenesis and function in the aging brain

  JE Le Belle, et al., bioRxiv - Neuroscience 2020

  Quote: ... EGFR (Cell Signaling Technology, 1:100), ID1 (Biocheck ...
• MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

  Dario Zimmerli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pSTAT1 (1:1000, Cell Signaling, # 8826) and beta-Actin (1:10.000 ...
• Endogenous neural stem cells modulate microglia and protect from demyelination

  Béatrice Brousse, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-EGFR (1/50; Cell Signaling), rat anti-CD68 (1/200 AbCam).
• Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2021

  Quote: ... SOX2 1:200 (Cell Signaling, #4900S), SOX9 1:200 (R&D Systems ...
• Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2021

  Quote: ... NESTIN 1:500 (Cell Signaling, #4760), IBA1 1:2000 (Wako Chemicals ...
• Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processes

  Annika Bub, et al., bioRxiv - Neuroscience 2021

  Quote: ... CD81 (1:1,000; #10037; Cell Signaling), Flotilin-1 (1:1,000 ...
• THE DYNAMIC INTERPLAY BETWEEN HOMEODOMAIN TRANSCRIPTION FACTORS AND CHROMATIN ENVIRONMENT REGULATES PRONEURAL FACTOR OUTCOMES

  Cheen Euong Ang, et al., bioRxiv - Genomics 2020

  Quote: ... rabbit-HSP90 (1:2500, Cell Signaling), rabbit-FLAG (1:500 ...
• Wilms Tumorigenesis in Human Kidney Organoids

  Verena Waehle, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SIX1 (Cell Signaling #12891; 1:200), SIX2 (Proteintech #11562-1-AP ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MITF (Cell Signaling, 12590s, 1:1000), AXL (Cell Signaling ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CTSB (1:1000; Cell Signaling, 31718), CTSD (1:1000 ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... AKT1 (1:1000; Cell Signaling, 9272), phospho(Ser473)-AKT1 (1:2000 ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CTSD (1:1000; Cell Signaling, 2284), VCP (1:400 ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... RPS6 (1:1000; Cell Signaling, 2317), phosphor(Ser240/244)-RPS6 (1:1000 ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ATG7 (1:500; Cell Signaling, 8558), RB1CC1 (1:1000 ...
• Mapping the Cellular Origin and Early Evolution of Leukemia in Down Syndrome

  Elvin Wagenblast, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-STAG2 (Cell Signaling, 1:50) and anti-GAPDH (Cell Signaling ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... PERK (Cell signaling #3192; 1/1000), phospho-PERK (Cell signaling #3179 ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... eIF2α (Cell Signaling #2103, 1/1000), phospho-eIF2α (Cell Signaling #3398 ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... Calnexin (Cell signaling #2679; 1/1000), α-Tubulin (Santa Cruz #sc-32293 ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... ATF4 (Cell Signaling #11815, 1/1000), CHOP (Cell Signaling #5554 ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... CHOP (Cell Signaling #5554, 1/1000), Bcl-xL (Cell Signaling #2764 ...
• Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

  Minchul Kim, Yao Zhang, Carmen Birchmeier, bioRxiv - Cell Biology 2020

  Quote: ... β-Tubulin (Cell Signaling 2128, 1:2000), Huwe1 (Abcam ab70161 ...