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351 - 400 of 1191 citations for 6 Pteridinemethanol 2 amino 9CI since 2019

• The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer

  Rhona Millar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-ERK1/2 (84ng/mL; Cell Signaling Technology, #4695); anti-AKT (34ng/mL ...
• The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response

  Sarayut Phasuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pERK1/2 (1:1000; Cell Signaling, Danvers, MA), anti-total ERK1/2 (1:1000 ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... p-ERK1/2 (Cell Signaling 4370; IB 1:1000).
• ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

  Cristina Aguirre-Portolés, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK (Cell Signaling Technology, p44/42 MAPK (Erk1/2) (137F5 ...
• Protective mitochondrial fission induced by stress responsive protein GJA1-20k

  Daisuke Shimura, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-MEK1/2 (1:1000, Cell Signaling Technology). After overnight primary antibody incubation at 4 °C ...
• Genetic or transcranial magnetic stimulation of B-RAF–MEK signaling promotes CST axon sprouting and functional regeneration

  Francesco Boato, et al., bioRxiv - Neuroscience 2022

  Quote: ... Primary antibodies were anti-MEK1/2 (Cell Signaling, 4694), anti-pMEK1/2 (Cell Signaling ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (#4370, Cell signaling), ATF-4 (#11815 ...
• Defective mitochondrial-lysosomal axis promotes extracellular vesicles release of mitochondrial components in Huntington’s Disease

  Margarida Beatriz, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-flotillin-2 (C42A3) (1:500, #3436,Cell Signaling), anti-calnexin (1:500 ...
• Collagen-VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche

  Vasileios Papalazarou, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-ERK1/2 (1:1000; 9102, Cell Signaling Technology), anti-GAPDH (1:1000 ...
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... MEK1/2 (Cell Signaling Technologies, Cat #4694; 1:1000).
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... ERK1/2 (Cell Signaling Technologies, Cat #4696; 1:2000), p-MEK (Cell Signaling Technologies ...
• Host Cell Rap1b mediates cAMP-dependent invasion by Trypanosoma cruzi

  Gabriel Ferri, Martin M. Edreira, bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho-p44/42 MAPK (pERK1/2, Cell Signaling) or anti-GAPDH (Santa Cruz Biotechnology ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling Technology, 137F5, 1:1000), pp90RSK1 (R&D Systems ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling technology; #4695, 1:1,000), anti-active β-Catenin (Cell signaling technology ...
• ADAP1 promotes latent HIV-1 reactivation by selectively tuning a T cell signaling-transcriptional axis

  Nora-Guadalupe P. Ramirez, et al., bioRxiv - Microbiology 2021

  Quote: ... Anti-ERK1/2 (Cell Signaling Technology, 4696 or 4695) (1:2000)
• Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma

  Arwin Groenewoud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-SLC7A11 and anti-ERK1/2 (Cell Signaling Technology), anti-di-phospho-ERK and anti-Vinculin (Sigma-Aldrich).
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho Myosin Light Chain 2 (Cell Signaling #3671), anti-Myosin Light Chain 2(Cell Signaling #3672) ...
• Pro-tumor and prothrombotic activities of hepsin in colorectal cancer cells and suppression by venetoclax

  Maria Carmen Rodenas, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (9101S, Cell Signaling Technologies, Werfen, Barcelona, Spain), pSTAT3(Tyr705 ...
• Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

  Max Koppers, et al., bioRxiv - Developmental Biology 2019

  Quote: ... 1:250 rabbit-anti-pERK1/2 (Cell Signaling, 9101). Secondary antibodies were diluted at ...
• Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

  Elizabeth Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... P-Smad 2/3 (1:1000; Cell Signaling; #8828), Linker P-Smad 2/3 (1:1000 ...
• Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease

  Brett K. Fulleylove-Krause, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-SIRT 2 (Cell Signaling, 12672, 1:1000), rabbit anti-SIRT 3 (Abgent ...
• Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes

  Sabrina Contino, et al., bioRxiv - Neuroscience 2020

  Quote: ... Anti-Presenilin 2 (1:1,000; Cell Signaling, Danvers, USA); Anti-Tubulin (1:3000 ...
• Addressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation

  Xiaotong Zhu, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-Erk1/2 (Cell signaling technology, cat. no. 4695).
• Hydroxylation of Actin Impairs Cell Motility Through Blocking its’ Histidine Methylation

  Zhenzhen Zi, et al., bioRxiv - Biochemistry 2021

  Quote: ... PHD-2/Egln1 (D31E11) Rabbit mAb (Cell Signaling, 4835s), EGLN3/PHD3 Antibody (Novus Biologicals ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling 4695, 1:2000), rabbit anti-phospho-PAK1 (S199/S204 ...
• SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

  Yen K. Lieu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-p-MAPKAPK-2 (MK2; T334) (Cell Signaling, 9595T), anti-α-Tubulin (Cell Signaling ...
• Zfp36l1 and Zfp36l2 balances proliferation and differentiation in the developing retina

  Fuguo Wu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and rabbit anti-Zfp36l1/2 (Cell signaling 2119,1:100). Secondary antibodies were purchased from Life Sciences.
• Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)

  Honglin Jiang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Erk1/2 (Cell Signaling Technology, 4696, Dilution: 1:1000); GAPDH (Cell Signaling Technology ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... P-ERK1/2 Thr202/Tyr204 (Cell Signaling Technology #4370), 1:2000 ...
• Androgen Receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR

  Bosen You, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Argonaute-2 (Ago2) (Cell Signaling Technology, #2897, Danvers, MA), IgG (Santa Cruz ...
• Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

  E. M. Poursani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p44/42 MAPK (ERK1/2) (9102S, Cell Signaling Technology), MMP-9 (D6O3H ...
• Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

  Abir Mukherjee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HK-2 (Cell Signaling Technology, cat# 2867, 1:1000), p-STAT3 Tyr 708 (Cell Signaling Technology ...
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho Myosin Light Chain 2 (Cell Signaling 3671) and secondary antibody anti-rabbit AlexaFluor 488 (Invitrogen A-21441) ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-ERK1/2 (1:200; 4370; Cell Signaling Technology), phospho-AKT (1:8,000 ...
• The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids

  Jennifer Rynne, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Antibodies used were: BRF1/2 (Cell Signaling Technology #2119), GR (Cell Signaling Technology #3660 ...
• Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

  Eleftheria Koropouli, et al., bioRxiv - Neuroscience 2022

  Quote: ... Neuropilin-2 (rabbit polyclonal, Cell Signaling, Cat no. 3366S); Neuropilin-2 (goat polyclonal ...
• PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties

  Tejashree Joglekar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling #4696); anti-KRAS (Sigma #WH0003845M1) ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... ERK1/2 (1:1000; 9102; Cell Signaling Technology, Inc.); phospho-AKT (Ser473 ...
• Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function

  Chao Chang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling Technology, #9102; RRID:AB_330744), goat polyclonal anti-EPHB2 (R&D Systems ...
• Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment

  Gabriela Traczyk, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-flotillin-2 (Cell Signaling, cat. No. 3436), donkey anti-sheep IgG-HRP (Jackson ImmunoResearch ...
• Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

  Mingrong Zuo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-ERK1/2(Thr202/Tyr204) (Cell Signaling Technology #4370S), total-ERK1/2 (Cell Signaling Technology #4696) ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal pSMAD 2/3 (Cell Signaling; 8828, Massachusetts, USA), monoclonal pSMAD 1/5/9 (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... MEK1/2 (Cell Signaling 1:1000, #9122, 1:1000), phospho-MEK1/2 S217/221 (Cell Signaling ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... SHP-1 or SHP-2 (all Cell Signaling Technology) followed by anti-rabbit Dylight649 (1:500 ...
• Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

  Baptiste Fischer, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit monoclonal ERK1/2 (1:50, Cell Signaling #4696), and mouse monoclonal Flag antibody (clone M2 ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Cox-2 (1:1,000, 9461, Cell Signaling Technology), anti-β-actin (1:2,000 ...
• Antagonistic pleiotropy plays an important role in governing the evolution and genetic diversity of SARS-CoV-2

  Ding-Chin Lee, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... rabbit anti-SARS-CoV-2 envelope (Cell signaling, #74698), rabbit anti-GAPDH (Genetex ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat.No.9102S, 1:1000), phospho-4EBP1 (Cell Signaling Technology ...
• Actin polymerization drives lumen formation in a human epiblast model

  Dhiraj Indana, et al., bioRxiv - Developmental Biology 2023

  Quote: ... phospho- myosin light chain 2 (Cell Signaling Technology #3674), Arp2/3 complex (Sigma-Aldrich MABT95) ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...