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251 - 300 of 1191 citations for 6 Pteridinemethanol 2 amino 9CI since 2019

• PROX1 transcription factor is a master regulator of myogenic and oncogenic features of rhabdomyosarcoma

  Nebeyu Yosef Gizaw, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Antibodies against PROX1 (11067-2-AP, Cell Signaling), HDAC1 (5356 ...
• Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

  Behnam Nabet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-ERK1/2 T202/Y204 (Cell Signaling, #4370), ERK1/2 (Cell Signaling ...
• Chronic high dietary sucrose induces sexually dimorphic metabolic adaptations in liver and adipose tissue

  Erin J Stephenson, et al., bioRxiv - Physiology 2020

  Quote: ... phospho-ACC1/2 Ser79 (#3661, Cell Signaling Technology), b-Tubulin (#MA5-16308 ...
• SILAC phosphoproteomics reveals unique signaling circuits in CAR-T cells and the inhibition of B cell-activating phosphorylation in target cells

  Alijah A. Griffith, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-Erk1/2 (Cell Signaling cat. 9107, Danvers, MA), α-Lck (Cell Signaling Technologies ...
• A molecular clock controls periodically driven cell migration in confined spaces

  Sung Hoon Lee, et al., bioRxiv - Systems Biology 2020

  Quote: ... Phospho Myosin Light Chain 2 (Cell Signaling, 3674S), Myosin Light Chain 2 (Cell Signaling ...
• Crystal structure of a novel guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi

  Christopher Lim, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit anti-Rac1/2/3 (2465, Cell Signaling), rabbit anti-Cdc42 (2466 ...
• Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement

  Ashley L. Kalinski, et al., bioRxiv - Neuroscience 2020

  Quote: ... α-ERK1/2 (1:5000, Cell Signaling Technologies, 9102). Horseradish peroxide (HRP)-conjugated α-rabbit secondary IgG (EMD Millipore ...
• Cancer exosomes harbor diverse hypoxia-targeted mRNAs and contribute toward tumor angiogenesis

  Pan Zhang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Erk1/2 (Cell Signaling Technology, Cat No. 4695), β-actin (Thermo Fisher Scientific ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Phospho-MEK1/2 (Cell Signaling, 9121, 1:1000), MEK1/2 (Cell Signaling ...
• Therapeutic vulnerability to ATR inhibition in concurrent NF1 and ATRX-deficient high-grade solid tumors

  Ming Yuan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Erk1/2 (#9102, 1:1000, Cell Signaling Technology),γH2AX (#9718 ...
• Therapeutic vulnerability to ATR inhibition in concurrent NF1 and ATRX-deficient high-grade solid tumors

  Ming Yuan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (#4370, 1:1000, Cell Signaling Technology), Erk1/2 (#9102 ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-phosphoERK1/2 (T202) (D13.14.4E) (Cell Signaling 4370S) lot 24 ...
• Host Cell Rap1b mediates cAMP-dependent invasion by Trypanosoma cruzi

  Gabriel Ferri, Martin M. Edreira, bioRxiv - Cell Biology 2022

  Quote: ... anti-p44/42 MAPK (ERK1/2, Cell Signaling), anti-phospho-p44/42 MAPK (pERK1/2 ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (Cell Signaling Technology, D13.14.4E, 1:1000), total ERK1/2 (Cell Signaling Technology ...
• Palmitoylation Couples DLK to JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling

  Jingwen Niu, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-panERK1/2 (Cell Signaling Technology, #9106), mouse anti-phosphoJNK (Cell Signaling Technology ...
• β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

  Shikai Hu, et al., bioRxiv - Pathology 2021

  Quote: ... p-Erk1/2 (Cell Signaling, 4370, 1:100), F4/80 (BioRad ...
• Sustained ErbB activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells

  Xu Hu, et al., bioRxiv - Neuroscience 2021

  Quote: ... Erk1/2 (1:5000, Cell signaling Technology, 9102), pErk1/2 (1:5000 ...
• A CLN6-CRMP2-KLC4 complex regulates anterograde ER-derived vesicle trafficking in cortical neurites

  SY Koh, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Phospho-CRMP-2 (T514 (Cell Signaling 9397), S522 (ECM BioSciences CP2191)) ...
• AMPK-dependent phosphorylation is required for transcriptional activation of TFEB/TFE3

  Mathieu Paquette, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-ACC1/2 (S79) (Cell Signaling Technology, 3661), 4EBP1 (Cell Signaling Technology ...
• Tegaserod maleate suppresses the growth of gastric cancer in vivo and in vitro by targeting MEK1/2

  Zitong Wang, et al., bioRxiv - Pathology 2022

  Quote: ... Anti-ERK1/2 (Cat#4695, Cell Signaling Technology), anti-MEK1(Cat#2352 ...
• A novel role for Myosin-Va in mitochondrial fission

  Jackeline S Araujo, et al., bioRxiv - Cell Biology 2019

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling: #137f5) Rabbit mAb ...
• Signaling Diversity Enabled by Rap1-Regulated Plasma Membrane ERK with Distinct Temporal Dynamics

  Jeremiah Keyes, et al., bioRxiv - Cell Biology 2019

  Quote: ... ERK1/2 (Cell Signaling Technology Cat# 9102, RRID:AB_330744) and phospho-ERK1/2 (Cell Signaling Technology Cat# 9101 ...
• Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

  Elizabeth Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... Smad 2/3 (1:1000; Cell Signaling; #8685S), P-Smad 1/5/8 (1:1000 ...
• NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

  Carolina Marques, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p-ERK1/2 (T202/Y204) (Cell Signaling Technology, #9101 ...
• Exploiting codon usage identifies RpS21 as an in vivo signal strength-dependent Ras/MAPK regulator

  Jessica K. Sawyer, et al., bioRxiv - Genetics 2019

  Quote: ... anti-p- ERK1/2 (Cell Signaling, 1:1000), anti-ERK1/2 (Cell Signaling ...
• Exploiting codon usage identifies RpS21 as an in vivo signal strength-dependent Ras/MAPK regulator

  Jessica K. Sawyer, et al., bioRxiv - Genetics 2019

  Quote: ... anti-p-MEK1/2 (Cell Signaling, 1:500), anti-MEK1/2 (Cell Signaling ...
• CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci

  J. Martinez-Fabregas, et al., bioRxiv - Immunology 2020

  Quote: ... anti-pT202/Y204-ERK1/2 (Cell Signaling, #4370L), anti-pT180/Y182-P38 (Cell Signaling ...
• The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection

  Anna Moskovskich, et al., bioRxiv - Cell Biology 2019

  Quote: ... phospho-MEK1/2 S217/221 (#9154, Cell Signaling), MEK1/2 (#9126 ...
• Melanoma plasticity is controlled by a TRIM28-JUNB mediated switch

  William A Nyberg, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-phospho-ERK1/2 (#9106, Cell Signaling Technologies), anti-pan-TEAD (#13295 ...
• SVEP1, a novel human coronary artery disease locus, promotes atherosclerosis

  In-Hyuk Jung, et al., bioRxiv - Genetics 2020

  Quote: ... anti-MCM-2 (#4007, Cell Signaling, 1:100) were used ...
• Sustained ErbB activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells

  Xu Hu, et al., bioRxiv - Neuroscience 2021

  Quote: ... pErk1/2 (1:5000, Cell signaling Technology, 4370), RIP3 (1:2000 ...
• Limited inhibition of multiple nodes in a driver network blocks metastasis

  Ali E. Yesilkanal, et al., bioRxiv - Cancer Biology 2020

  Quote: p44/42 MAPK (ERK1/2) (Cell Signaling, 9107)
• Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells

  Dhruv Raina, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-pERK1/2 1:1000 (4370S, Cell Signaling), and anti-total ERK1/2 1:1000 (ab36991 ...
• Constitutive signal bias mediated by the human GHRHR splice variant 1

  Zhaotong Cong, et al., bioRxiv - Molecular Biology 2021

  Quote: ... pERK1/2 (1:1000; 9101s, Cell Signaling Technology), β-tubulin (1:1000 ...
• IL-27R signaling serves as immunological checkpoint for NK cells to promote hepatocellular carcinoma

  Turan Aghayev, et al., bioRxiv - Immunology 2020

  Quote: ... anti-pERK1/2 (1:400; Cell Signaling, 4370) or anti-IL-27Rα (34N4G11 ...
• Aberrant localization of CDC42 C-terminal variants to the Golgi apparatus drives pyrin inflammasome-dependent autoinflammation

  Masahiko Nishitani-Isa, et al., bioRxiv - Immunology 2021

  Quote: ... anti-p-ERK1/2 (Cell Signaling, 1:1000), anti-p65 (Cell Signaling ...
• Aberrant localization of CDC42 C-terminal variants to the Golgi apparatus drives pyrin inflammasome-dependent autoinflammation

  Masahiko Nishitani-Isa, et al., bioRxiv - Immunology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, 1:1000), anti-p-ERK1/2 (Cell Signaling ...
• Sortilin exhibits tumor suppressor-like activity by limiting EGFR transducing function

  E. Lapeyronnie, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (#9102, 1:1000 dilution, Cell Signaling), pAKT (Ser 473 ...
• Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

  Christina Plattner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-ERK1/2 (Cell Signaling, #4377S, 1:1000), phosho-MEK1 (Invitrogen ...
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Myosin Light Chain 2(Cell Signaling #3672), anti-phospho-PAK (Cell signaling #2605S) ...
• The Cul5 E3 Ligase Complex Is a Key Negative Feedback Regulator of TCR/IL2 Signaling and Anti-Tumor Activity in CD8⁺ T Cells

  Xiaofeng Liao, et al., bioRxiv - Immunology 2022

  Quote: ... anti-pERK1/2 (Cell Signaling Technology, Cat. 9101), Rabbit polyclonal IgG anti-Cul5 (Thermo Scientific ...
• mRNA interactions with disordered regions control protein activity

  Yang Luo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-ZFP36L1/2 (2119, Cell Signaling Technology), rabbit anti-SNIP1 (14950-1-AP ...
• SHIP2 controls matrix mineralization by regulation of the RhoA/ROCK pathway and remodeling of the actin cytoskeleton

  Anais Fradet, Jamie Fitzgerald, bioRxiv - Cell Biology 2022

  Quote: ... pErk1/2 Thr202/Tyr204 (Cell Signaling Technologies #9101) 1/1000 ...
• Lipid Dysregulation Unveil the Intricate Interplay of Lysosomal and Mitochondrial Changes in Frontotemporal Dementia with GRN Haploinsufficiency

  Jon Ondaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... LAMP-2 (1:1 000, #49067, Cell Signaling), LC3Bxp (1:1 000 ...
• Nutrient Sensing Receptor GPRC6A Regulates mTORC1 Signaling and Tau Biology

  Chao Ma, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERK1/2 pT202/Y204 (Cell Signaling Tech, #9101), mTOR (Cell Signaling Tech ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... 4E-BP1/2 (#2845, 1:1,1000; Cell Signaling), phospho-mTOR Ser2448 (#2971 ...
• MSK1 absence hinders BDNF-dependent striatal neurodevelopment and leads to schizophrenia symptoms

  Natalia Varela-Andrés, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit monoclonal anti-pERK1/2 (#9101; Cell Signaling) 1:3000 ...
• Med12 cooperates with multiple differentiation signals to enhance embryonic stem cell plasticity

  Max Fernkorn, Christian Schröter, bioRxiv - Cell Biology 2024

  Quote: ... anti-pERK1/2 1:1000 (4370S, Cell Signaling), anti-total ERK1/2 1:1000 (ab36991 ...
• Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

  He-Yun Hsiao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pMEK1/2 (Cell Signaling Technology Cat# 9121, RRID:AB_331648), pSMAD5 (Abcam Cat# ab92698 ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... phospho-ERK1/2 (Cell Signaling Tech pThr202/pTyr204) (#9101) ...