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351 - 400 of 10000+ citations for 5 Methoxy 1 Triisopropylsilyl 1H Pyrrolo 2 3 B Pyridine since 2020

• Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks

  Quen J. Cheng, et al., bioRxiv - Immunology 2023

  Quote: ... pIRF-3 (Rabbit IgG, 1:1000, Cell Signaling Technology 4947), p65(RelA ...
• Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

  Patricia D.B. Tiburcio, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cleaved Caspase-3 (Cell Signaling Technology 9664, RRID:AB_2070042; 1:1,000), Caspase-7 (Cell Signaling Technology 12827 ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... Cleaved Caspase-3 (Asp175, Cell Signaling Technology, 9661, 1:500), Cleaved Caspase-8 (Asp384 ...
• Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization

  Junichi Saito, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-cleaved caspase-3 (Cell signaling, 9664; 1:250), rabbit anti-EGR1 (Cell signaling ...
• MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability

  Neel Jasani, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cleaved Caspase 3 (1:200, Cell Signaling Technologies, Cat. # 9661) and Ki-67 (1:100 ...
• Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia

  Meghraj S Baghel, et al., bioRxiv - Neuroscience 2024

  Quote: ... and cleaved caspase 3 (1:1000; 5A1E; Cell Signaling Technology). Immunoblots were developed using enhanced chemiluminescence method (Millipore Corp. ...
• Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

  David Lozano-Muñoz, et al., bioRxiv - Neuroscience 2024

  Quote: ... and rabbit Cleaved caspase-3 (1:100, Cell Signaling, 9661) for mouse samples ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit anti-Caspase-3 (1:500, Cell Signaling 9579) overnight at 4°C ...
• Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model

  Junxiang Yin, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Cleaved Caspase 3 (CC3, Cell signaling, #9664, 1:1000) at 4°C overnight ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-cleaved Caspase-3 (1:1000, Cell Signaling, #9661), rabbit anti-Mef2c (1:400 ...
• TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation

  Stefano Sellitto, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Cleaved Caspase 3 1:1000 (Cell Signaling Technology, 9661S), anti-Caspase 3 1:1000 (Novus Biologicals ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-cleaved caspase-3 (9661, Cell Signaling, 1:1000), rabbit anti-Bcl-2 (3498 ...
• Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways

  Sinwoo Hwang, Cameron Baker, Martha S. Field, bioRxiv - Biochemistry 2024

  Quote: ... Caspase-3 (1:1000, 9662, Cell Signaling, Danvers, MA, USA), Cleaved caspase-3 (1:1000 ...
• Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis

  Nicolas V. Janto, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:400 anti-Cleaved caspase 3 (CC3; Cell Signaling; 9661S), 1:200 anti-OLFM4 (Cell Signaling ...
• Induction of NASH in the Nwd1^−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress

  Seiya Yamada, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-LC3A/B (D3U4C) XP (rabbit monoclonal, #12741, RRID: AB_2617131, Cell Signaling Technology; 1:200 for IHC, 1:2000 for WB), anti-Nwd1 (rabbit polyclonal generated via immunization with the recombinant mouse Nwd1 protein [18] ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (#4695S, 1:1000, Cell Signaling), p-STAT3 Y705 (#4370S ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), SOX2 1:100 (R&D AF2018) ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... MEK1/2 1:1000 (Cell Signaling 8727s), and GAPDH 1:10,000 (Sicgen AB0049-20 ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), and Xen1 1:100 (deposited to Developmental Studies Hybridoma Bank (DSHB ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... Erk-1/2 (Cell Signaling Technology #9102) and β-Actin (Cell Signaling Technology #3700) ...
• Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer

  Suzann Duan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COX-2 (1:50, Cell Signaling Technologies), and GAPDH (Cell Signaling Technologies ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Erk1/2 (1:1000; L34F12; Cell Signaling), phospho(Ser473)-AKT (1:2000 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MEK1/2 (1:1000; L38C12; Cell Signaling), phospho(Thr44/Tyr42)-ERK1/2 (1:1000 ...
• STAT3 but not STAT5 contributes to the protective effect of electro-acupuncture against myocardial ischemia/reperfusion injury

  Hui-Hui Guo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Bcl-2 (1:1000, Cell Signaling, #3498), Cyt c (1:1000 ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... ERK1/2 (Cell Signaling, 9102, 1:2,000), p-ERK1/2 (T202/Y204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MEK1/2 (1:500 Cell Signaling Technology), phospho-ERK1/2 (Thr202/Tyr204 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MEK1/2 (Cell Signaling, 9122, 1:1000), total H3 (Abcam ...
• Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

  Hui Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-ERK1/2 (1:2000, Cell Signaling), and anti-AKT (1:2000 ...
• Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue

  Megan Moruzzi, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 1:1000 (Cell Signaling, #9102S), α-tubulin (Sigma Aldrich ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pERK1/2 (1:1000, Cell Signaling), anti-MBP (1:1000 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pERK1/2 (1:500, Cell Signaling), anti-pERK1/2 (1:1000 ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (#9102, 1:1,000; Cell Signaling); phospho-p70S6K1 Thr389 (#9205 ...
• CRIPTO promotes extracellular vesicle uptake and activation of cancer associated fibroblasts

  David W. Freeman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (L34F12, Cell Signaling, 1:2000), Vinculin (Clone EPR8185 ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pERK1/2 (1:1,000; Cell Signaling, #9101), ERK1/2 (1:1,000 ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:1,000; Cell Signaling, #4695), pAKT (Thr308 ...
• Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

  Lei Wang, et al., bioRxiv - Immunology 2024

  Quote: ... ERK1/2 (4695S, Cell Signaling, 1: 1000), phospho-ERK1/2 (4370S ...
• Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome

  Rosalba Olga Proce, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERK1/2 (Cell Signaling, #4695, 1:500), MNK1 (Cell Signaling ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or Cleaved Caspase-3 (CC3; Cell Signaling, 1:150, 1 h at room temperature). Slides were washed thrice in TBST prior to incubation with a pre-diluted HRP-conjugated secondary antibody (Nacalai USA Histofine) ...
• Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

  Shinya Matsuda, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phospho-Smad1/5 (1:200; Cell Signaling), anti-Brk (1:1.000 ...
• Neurotrophin signaling is modulated by specific transmembrane domain interactions

  María L. Franco, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-phosphoTyr674/5 (1:1000, Cell Signaling); rabbit anti-TrkA (1:1000 ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Exportin 5 (1:1000) (Cell Signaling #12565), anti-β-actin (1:5000 ...
• Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

  Lei Wang, et al., bioRxiv - Immunology 2024

  Quote: ... Antibodies: STAT-5 (94205S, Cell Signaling, 1: 1000), phos-STAT5 (9359S ...
• Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes

  Amos A. Lim, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-NKX2-5 (Cell Signaling, 8792S, 1:1000), anti-NPPA (Abcam ...
• Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes

  Amos A. Lim, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-NKX2-5 (Cell Signaling, 8792S, 1:1000). To detect unconjugated primary antibodies the following secondary antibodies were used ...
• Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice

  Hyung-seok Kim, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti- pSmad1/5 (1:1000, Cell Signaling, RRID:AB_491015) or anti-actin (1:10,000 ...
• The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds

  Janani Ramachandran, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and then incubated with the following primary antibodies for 2 hours at room temperature in 5% BSA: 1:1000 anti-SMARCC1 (Cell Signaling Technologies cat. #11956T), 1:1000 anti-SMARCA4 (Cell Signaling Technologies cat ...
• Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis

  Nicholas D. LeBlond, et al., bioRxiv - Cell Biology 2020

  Quote: ... LC3A/B (D3U4C) (Cell Signaling Technology - 12741), mTOR (Cell Signaling Technology - 2983) ...
• The role of hepatitis B virus surface protein in inducing Sertoli cell ferroptosis

  Chengshuang Pan, et al., bioRxiv - Cell Biology 2022

  Quote: ... or b-actin (Cell Signaling Technology; #4970) at 4°C overnight ...
• Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation

  Lene Clausen, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-LC3A/B (D3U4C, Cell Signaling Technology), anti-GAPDH (14C10 ...
• FKBPL and FKBP8 regulate DLK degradation and neuronal responses to axon injury

  Bohm Lee, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-LC3A/B (Cell Signaling, CST-12741), anti-SCG10 (Novus Biologicals ...