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251 - 300 of 10000+ citations for 5 Methoxy 1 Triisopropylsilyl 1H Pyrrolo 2 3 B Pyridine since 2020

• Removal of the catalytic subunit of DNA-protein kinase in the proximal tubules promotes DNA and tubular damage during kidney injury

  M. Swanson, et al., bioRxiv - Physiology 2024

  Quote: ... cleaved caspase-3 (cat #9661, 1:200; Cell Signaling), and Ki67 (cat #15580 ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-caspase-3 (9662, Cell Signaling, 1:1000), rabbit anti-cleaved caspase-3 (9661 ...
• Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

  Jill E. Hunter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK 1/2 (9102 Cell Signaling), AKT (phospho S473 ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... MMP-2 (Cell Signaling; 1:1000), TIMP-1 (Sino Biological ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... MEK1/2 (Cell Signaling 1:1000, #9122, 1:1000), phospho-MEK1/2 S217/221 (Cell Signaling ...
• SLX4IP-mediated telomere maintenance is essential for androgen receptor-independent castration-resistant prostate cancer

  Tawna L. Mangosh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1:5 000 p21 (Cell Signaling, 2947).
• Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

  Vanitha Nithianandam, et al., bioRxiv - Neuroscience 2023

  Quote: ... pSMAD1/5/9 (1:2000, Cell Signaling), GABARAP (1:2000 ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... (5) FoxP3 (1:400, 126553; Cell Signaling)–Opal 650 ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pSMAD1/5/9 (1:100 Cell Signaling), FOXA2 1:500 (Abcam) ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pSMAD1/5/9 (1:100 Cell Signaling), FOXA2 1:500 (Abcam) ...
• Widely used mutants of eiger, encoding the Drosophila Tumor Necrosis factor, carry additional mutations in the NimrodC1 phagocytosis receptor

  Albana Kodra, et al., bioRxiv - Genetics 2020

  Quote: ... Larval carcasses were stained with Rabbit anti-Cleaved Caspase-3 (Cas-3) at 1:100 (Cell Signaling). Secondary antibodies were purchased from Jackson Immunoresearch ...
• Efficient enzyme-free isolation of brain-derived extracellular vesicles

  A. Matamoros-Angles, et al., bioRxiv - Neuroscience 2024

  Quote: ... These primary antibodies in a dilution of 1:1,000 were used: 14-3-3 (#9636S, Cell Signaling), ADAM10 (#ab124695 ...
• NOK promotes tumorigenesis through coordinating epidermal growth factor receptor to boost the downstream signaling in breast cancer

  Yinyin Wang, et al., bioRxiv - Cell Biology 2024

  Quote: ... AKT1/2/3 (9272) and SHC (2432) were purchased from Cell Signaling (Danvers, MA, USA). Antibody against phosphotyrosine (4G10 ...
• Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation

  Tomoki Kuwahara, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-cathepsin B [D1C7Y] (Cell Signaling), anti-LBPA [6C4] (Echelon) ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... and Cyclophilin B (#43603, Cell signaling). For secondary antibodies ...
• Bi-steric mTORC1-selective Inhibitors activate 4EBP1 reversing MYC-induced tumorigenesis and synergize with immunotherapy

  Wadie D. Mahauad-Fernandez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... granzyme B (Cell Signaling Technologies, D6E9W) and the same antibodies used in western blot and NIA for pS6RP ...
• AXL-TBK1 driven nuclear AKT3 promotes metastasis

  Emily N. Arner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-B-Catenin (8480, Cell Signaling), mouse anti-human Twist (Twist2C1a ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... Granzyme B (Cell Signaling Technology #4275), LCK (Thermo Fisher PA5-34653) ...
• A new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer

  EunJung Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... LC3A/B (Cell Signaling Technology, D3U4C), Atg5 (Cell Signaling Technology ...
• A human urothelial microtissue model reveals shared colonization and survival strategies between uropathogens and asymptomatic bacteria

  Carlos Flores, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-LC3A/B (Cell Signaling), rabbit anti-Rab27a (Invitrogen ...
• The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

  Yanqiu Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cyclin B (Cell signaling technology, #4138), phosphor-CDK substrates (Cell signaling technology ...
• The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

  Yanqiu Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... Aurora B (Cell Signaling technology, #3094), CDK1 (Cell signaling technology ...
• HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes

  Alison Barrett, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and Buffer B (Cell Signaling. #7007S). MNase enzyme was prepared in-house using Addgene plasmid # 136291 (Yan et al. ...
• Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation

  Alexandra Blanco, et al., bioRxiv - Microbiology 2024

  Quote: ... and B-actin (Cell Signaling Technologies) at dilutions recommended by the manufacturer ...
• Group A Streptococcus Induces Lysosomal Dysfunction in THP-1 Macrophages

  Scott T. Nishioka, et al., bioRxiv - Microbiology 2023

  Quote: ... Cathepsin B (Cell Signaling Technology, D1C7Y), LAMP-1 (Cell Signaling Technology ...
• Universal high-throughput image quantification of subcellular structure dynamics and spatial distributions within cells

  Andrew Martin, et al., bioRxiv - Cell Biology 2024

  Quote: ... LC3A/B (Cell Signaling Technology, 12741), p62 (Abcam ...
• Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

  Avital Licht-Murava, et al., bioRxiv - Neuroscience 2022

  Quote: ... ERK1/2 (1:1000 mouse anti-total ERK1/2; Cell Signaling Technology #4696 ...
• Prophage-encoded methyltransferase drives adaptation of community-acquired methicillin-resistant Staphylococcus aureus

  Robert J. Ulrich, et al., bioRxiv - Microbiology 2024

  Quote: ... The sections were washed twice with PBS and incubated in 2% BSA plus TBS with primary antibody [1:80 dilution rabbit anti-5-mC antibody (Cell Signaling Technology, #D3S2Z) at 4°C overnight ...
• Autophagy suppression in DNA damaged cells occurs through a newly identified p53-proteasome-LC3 axis

  D’Feau J. Lieu, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit monoclonal anti-LC3A/B antibodies (1:3000 dilution in TBST; #12741, Cell Signaling Technology, USA), or β-actin (1:10000 dilution in TBST ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... P-Smad 1/5 (1:200, RRID:AB_491015, #9516, Cell Signaling Technology), CC1 (1:100 ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-phospho SMAD 1/5/9 (1:1000, 13820, Cell Signaling), anti-ERK2 (1:1000 ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Anti-phospho SMAD 1/5/9 (1:500, 13820, Cell Signaling) and anti-ERK2 (1:50 ...
• LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK

  Joanna Filipowska, et al., bioRxiv - Physiology 2024

  Quote: ... Cleaved-Casapase-3 staining was performed using anti-Cleaved-Casapase-3 antibody (1:200, Cell Signaling Technologies, MA) and secondary Alexa Fluor 488 anti-rabbit antibody (Life Technologies ...
• LRBA balances antigen presentation and T-cell responses via autophagy by binding to PIK3R4 and FYCO1

  Elena Sindram, et al., bioRxiv - Immunology 2024

  Quote: ... followed by 1h incubation with anti-mouse or anti-rabbit AF488 or AF647 antibodies (Cell Signaling). After staining ...
• Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation

  Adele Stewart, et al., bioRxiv - Neuroscience 2021

  Quote: ... and phospho-ERK 1/2 (Cell Signaling, RRID:AB_331646; 1:1000).) ...
• V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

  Miriam Formica, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-ERK 1/2 1:1000 (4695, Cell Signaling). Western blots protein levels were analyzed using Image Lab (Biorad).
• AI boosted molecular MRI for apoptosis detection in oncolytic virotherapy

  Or Perlman, et al., bioRxiv - Biophysics 2020

  Quote: ... or cleaved caspase 3 (9579, Cell Signaling Technology; 1:150) diluted as recommended by the manufacturer with TBST ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-cleaved caspase 3 (1:100; Cell Signaling Technology #CST9661), and anti-phospho-ERBB3 (1:100 ...
• A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis

  Teng Teng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-rabbit cleaved caspase-3 (Cell signaling, 9661, 1:300), anti-goat p63 (R&D ...
• Differential regulation of cranial and cardiac neural crest by Serum Response Factor

  Colin J. Dinsmore, Philippe Soriano, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-cleaved Caspase 3 (Cell Signaling 9665, 1:400), rabbit anti-phospho Histone H3 (Ser10 ...
• RNA-guided cell targeting with CRISPR/RfxCas13d collateral activity in human cells

  Peiguo Shi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Cleaved Caspase 3 antibody (Cell signaling technology, 9661T, 1:500) was used for detecting the expression of cleaved Caspase 3 ...
• Vestibular and auditory hair cell regeneration following targeted ablation of hair cells with diphtheria toxin in zebrafish

  Erin Jimenez, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit cleaved Caspase-3 (Cell Signaling #9661, 1:300-dilution), Alexa Fluor 568 goat anti-rabbit IgG (1:1000-dilution).
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... R-anti-14-3-3ε (Cell Signaling Technology, 1:1000), M-anti-Flag M2 (Sigma ...
• Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy

  Lindsey M. Euscher, et al., bioRxiv - Bioengineering 2022

  Quote: ... and rabbit cleaved caspase-3 (1:200; Asp175, Cell Signaling). Alexa Fluor 488- ...
• NOX4 inhibition promotes the remodeling of dystrophic muscle

  David W. Hammers, bioRxiv - Cell Biology 2022

  Quote: ... and anti-active caspase-3 (1:1000; Cell Signaling #9661) primary antibodies ...
• The Initiation Knot is a Signaling Center Required for Molar Tooth Development

  Isabel Mogollón, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit polyclonal cleaved caspase 3 (1:400, Cell Signaling Technologies) or goat polyclonal sonic hedgehog antibody (1:100 ...
• c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

  Abigail O. Smith, et al., bioRxiv - Genetics 2021

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (1:1,000, Cell Signaling Technology # 3683S), phospho T180/Y182 p38 ...
• Reemployment of Kupffer’s vesicle cells into axial and paraxial mesoderm via transdifferentiation

  Takafumi Ikeda, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-cleaved caspase-3 (1/500, 9661, Cell Signaling Technology), anti-phospho Histone H3 (1/500 ...
• Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids

  Dina Ivanyuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Caspase 3 (1:500, Cell Signaling Technology 9664T). For thioflavin T immunostaining ...
• O-GlcNAcylation, oxidation and CaMKII contribute to atrial fibrillation in type 1 and type 2 diabetes by distinct mechanisms

  Olurotimi O. Mesubi, et al., bioRxiv - Molecular Biology 2020

  Quote: ... cleaved caspase-3 (1:1000, catalog 9662, Cell Signaling Technology), GAPDH (1:10,000 ...