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3251 - 3300 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons

  Hu Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... P62 (Cell Signaling, #8025, 1:1000), CytC (Cell Signaling ...
• Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

  Léa Broca-Brisson, et al., bioRxiv - Neuroscience 2023

  Quote: ... PAK1 1:1000 (Cell signaling, #2602), MAP1B 1:1000 (Sigma-Aldrich ...
• Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

  Stephanie E. Sansbury, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (Cell Signaling 2118, 1:2000), IRDye 680LT Goat anti-Rabbit (LI-COR 926-68021 ...
• TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells

  D. Wünkhaus, et al., bioRxiv - Cell Biology 2023

  Quote: ... TFEB (Cell Signaling, 4240, 1:500), Cathepsin B (R&D ...
• Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies

  Hugo C. Medina-Munoz, et al., bioRxiv - Genomics 2023

  Quote: ... Torin-1 (Cell Signaling, Cat # 14379) dissolved in dimethyl sulfoxide (DMSO ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... Akt (#9272, Cell signaling, 1:1000), Phospho-p44/42 MAPK (Erk1/2 ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: (1:1000; Cell Signaling Technology; #3686), and GAPDH (1:4000 ...
• Caspar determines primordial germ cell identity in Drosophila melanogaster

  Subhradip Das, et al., bioRxiv - Genetics 2024

  Quote: ... 1:200 (#2648, Cell Signaling Technology); Rabbit anti-Oskar ...
• Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

  H. Carlo Maurer, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LDHA (1:1000, Cell Signaling, #3582S), GAPDH (1:1000 ...
• Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

  H. Carlo Maurer, et al., bioRxiv - Cancer Biology 2024

  Quote: ... HIF2A (1:1000, Cell Signaling, #7096S), BMAL2 (1:500 ...
• Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

  H. Carlo Maurer, et al., bioRxiv - Cancer Biology 2024

  Quote: ... GAPDH (1:1000, Cell Signaling, #2118S) and Tubulin (1:1000 ...
• Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

  Sadra Bakhshandeh, et al., bioRxiv - Bioengineering 2024

  Quote: ... GAPDH (1:1000, 2118, Cell Signaling) was used as housekeeping gene and HRP-linked antibody 7074 (1:1000 ...
• A Novel ARNT-Dependent HIF-2α Signaling as a Protective Mechanism for Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction

  Karim Ullah, et al., bioRxiv - Cell Biology 2024

  Quote: ... ARNT (# 5537, Cell Signaling 1:500), GAPDH (# 5174 ...
• A Novel ARNT-Dependent HIF-2α Signaling as a Protective Mechanism for Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction

  Karim Ullah, et al., bioRxiv - Cell Biology 2024

  Quote: ... GAPDH (# 5174, Cell Signaling, 1: 5000), HIF1A (# NB100-479 ...
• NAD⁺ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages

  Jasper Iske, et al., bioRxiv - Immunology 2024

  Quote: ... P-STAT-1 (#9167S, Cell Signaling), STAT-1 (#9172S ...
• Tuning of granulopoietic signaling by de novo designed agonists

  Timo Ullrich, et al., bioRxiv - Bioengineering 2024

  Quote: ... STAT3 1:1000 (Cell Signaling, #12640S), phosphorylated STAT3 (Tyr705 ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-FOXO3 (1:1000, Cell signaling), α-pFOXO3 (1:1000 ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Ki67 (1:1000, 12202, Cell Signaling), Phospho Serine 473 AKT (1:45 ...
• Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress

  Shiyun Cao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... NCoR1 (1:1000, Cell Signaling Technology), MafF (1:1000 ...
• Unravelling biological processess and EGFR pathway regulation by the receptor-like protein tyrosine phosphatase PTPRH in non-small cell lung cancer

  Mylena M. O. Ortiz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... EGFR 1:1000 (Cell Signaling #4267), B-actin 1:1000 (Cell Signaling #4967) ...
• Unravelling biological processess and EGFR pathway regulation by the receptor-like protein tyrosine phosphatase PTPRH in non-small cell lung cancer

  Mylena M. O. Ortiz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... AKT 1:1000 (Cell Signaling #4685), and Vinculin 1:1000 (Cell Signaling #13901) ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Col1a1 (1:200, 93668, Cell Signaling), Ki67 (1:1000 ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PTEN (Cell Signaling, 9559, 1:1000), HSC70 (Santa Cruz Biotechnology ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ARID1A (1:200, 12354, Cell Signaling), Col1a1 (1:200 ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ARID1B (Cell Signaling, 92964, 1:1000), AR (Santa Cruz ...
• FDA-approved PDE4 inhibitors reduce the dominant toxicity of ALS–FTD-associated CHCHD10^S59L

  Swati Maitra, et al., bioRxiv - Neuroscience 2024

  Quote: ... LC3B (Cell Signaling Technology, 1:250).
• The Dual Roles of the CXCL10-CXCR3 Axis and Its Therapeutic Potential in Osteosarcoma

  Benjamin B. Gyau, et al., bioRxiv - Cancer Biology 2024

  Quote: ... CXCL10 (1:1000, Cell Signaling, 14969). Secondary antibodies used were anti-rabbit and anti-mouse IgG HRP-linked antibodies (1:5000 ...
• Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

  Lei Wang, et al., bioRxiv - Immunology 2024

  Quote: ... GAPDH (5174S, Cell Signaling, 1: 5000).
• Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

  Lei Wang, et al., bioRxiv - Immunology 2024

  Quote: ... AKT (9272S, Cell Signaling, 1:1000), phospho-AKT (4060S ...
• PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance

  Zhiyi Chen, et al., bioRxiv - Cell Biology 2024

  Quote: ... CTH (1:1000, D4E9J, Cell Signaling) SELENON (1:1000 ...
• RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability

  Vincent E. Provasek, et al., bioRxiv - Biochemistry 2024

  Quote: ... and PARP-1 (Cell Signaling #9542).
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-RIG-I (1:1000; Cell Signaling), α-IRF3 (1:1000 ...
• Hyperactive mTORC1/4EBP1 Signaling Dysregulates Proteostasis and Accelerates Cardiac Aging

  Weronika Zarzycka, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Ubiquitin (1:1000, #58395S – Cell Signaling). Membrane was incubated with secondary antibody conjugated with HRP and proteins were visualized by using chemiluminescence assay (Pierce ...
• Coordination of transcription-coupled repair and repair-independent release of stalled RNA polymerase II in response to transcription-blocking lesions

  Yongchang Zhu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:1000 (Cell Signaling Technology, 4499); mouse anti-ubiquitin monoclonal antibody ...
• Biomarker Identification by Proteomic Analysis of Vitreous Humor and Plasma in Diabetic Retinopathy

  Qian Huang, et al., bioRxiv - Physiology 2024

  Quote: ... 1:200 PMSF (Cell Signaling #8553S), and 1:500 EDTA (Thermo Scientific ...
• Microglia mediate the early-life programming of adult glucose control

  M Valdearcos, et al., bioRxiv - Physiology 2024

  Quote: ... glucagon (1:100, rabbit, Cell Signaling) and somastotatin (1:500 ...
• ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance

  Ayako Fukunaka, et al., bioRxiv - Cell Biology 2024

  Quote: ... PKA (1:1000; Cell Signaling, #5842) and anti-GAPDH (1:3,000 ...
• A human-specific enhancer fine-tunes radial glia potency and corticogenesis

  Jing Liu, et al., bioRxiv - Neuroscience 2024

  Quote: ... NeuroD2 (Cell Signaling,24307S,1/300); PH3 (Millipore ...
• Identification of genetic modifiers of Huntington’s disease somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing

  Ricardo Mouro Pinto, et al., bioRxiv - Genetics 2024

  Quote: ... MSH2 (1:1000, D24B5, Cell Signaling), MSH3 (1:5 ...
• THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA

  Florentin Pastor, et al., bioRxiv - Microbiology 2024

  Quote: ... DYRK1B (Cell Signaling 5672, 1:1000), HBc (provided by A ...
• SNX10 regulates the clearance of mitochondrial proteins and mitochondrial bioenergetics

  Laura Trachsel-Moncho, et al., bioRxiv - Cell Biology 2024

  Quote: ... GAPDH (Cell signaling, #5174, 1:1000) GFP (Takara ...
• Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization

  Junichi Saito, et al., bioRxiv - Developmental Biology 2024

  Quote: ... EGR1 (Cell signaling, 4154; 1:1000), S1PR1 (Proteintech ...
• The Conserved Transcription Factor Krüppel Regulates the Survival and Neurogenesis of Mushroom Body Neuroblasts in Drosophila Adult Brains

  Jin Man, et al., bioRxiv - Developmental Biology 2024

  Quote: ... DAPI (Cell Signaling Technology, 1:1000).
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... RHAMM (#E7S4Y, Cell signaling, 1:1000), TGF-β1 (#ab179695 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... GAPDH (#D16H11, Cell signaling, 1:1000), and Tubulin (#ab6046 ...
• Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

  Abdulkadir Ozkan, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:250 (Cell Signaling Technology, 2306S); rabbit anti-FOG2 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... ROCK2 (#8236, Cell signaling, 1:1000), GAPDH (#D16H11 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-cGAS (1:1000; Cell Signaling), α-STING (1:1000 ...
• Purkinje Cell-specific Deficiency in SEL1L-HRD1 Endoplasmic Reticulum-Associated Degradation Causes Progressive Cerebellar Ataxia in Mice

  Mauricio Torres, et al., bioRxiv - Neuroscience 2024

  Quote: ... GFAP (Cell Signaling, 3670, 1:2,000), anti-ATF4 (Cell Signaling ...
• Purkinje Cell-specific Deficiency in SEL1L-HRD1 Endoplasmic Reticulum-Associated Degradation Causes Progressive Cerebellar Ataxia in Mice

  Mauricio Torres, et al., bioRxiv - Neuroscience 2024

  Quote: ... eIF2⍺ (Cell Signaling, 9722, 1:1,000), and p-eIF2⍺ (Cell Signaling ...