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201 - 250 of 1267 citations for 2 CHLOROMETHYL 6 METHOXY 1H BENZO D IMIDAZOLE since 2020

• Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions

  Johannes F. Vogt, et al., bioRxiv - Immunology 2024

  Quote: ... p-Erk1/2 (Cell Signaling #9106), a-tubulin (Cell Signaling #2144) ...
• Loss of the Inv(16) Oncogene CBFB::MYH11 Eliminates Leukemia from the Blood and Spleen, but not the Bone Marrow

  Sipra Panda, et al., bioRxiv - Cancer Biology 2024

  Quote: ... BCL-2 (Cell Signaling Technology, MA), and GFP (Invitrogen ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PAK1/2/3 (Cell Signaling, # 2604S), pLIMK1/2 (Cell Signaling ...
• Adverse neurological effects of short-term sleep deprivation in aging mice are prevented by SS31 peptide

  Jinzi Wu, Yan Dou, Warren C. Ladiges, bioRxiv - Pathology 2020

  Quote: ... The primary antibodies used were N-methyl-D-aspartate (NMDA) receptor (Cell Signaling Technology, 4207), p-CREB (Cell Signaling Technology ...
• Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers

  Tomoko Marumo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... for 3 d and stained with anti-SDHA monoclonal antibody (Cell Signaling Technology, MA, USA) and anti-ACADV polyclonal antibody (Novus Biologicals ...
• SIRPα sequesters SHP-2 to promote IL-4/13 signaling and alternative activation of macrophages

  Lei Shi, et al., bioRxiv - Immunology 2021

  Quote: ... and phospho-SHP-2 was detected with an anti-phospho-SHP-2 (Tyr542) antibody (Cell Signaling Technology). Alternatively ...
• TGF-β-driven downregulation of the Wnt/β-Catenin transcription factor TCF7L2/TCF4 in PDGFRα⁺ fibroblasts

  Osvaldo Contreras, et al., bioRxiv - Cell Biology 2020

  Quote: ... the inhibitor of MEK1/2/ERK1/2 kinases UO126 (used at 10 μM; 9903, Cell Signaling Technology), Smad3 inhibitor SIS3 (used at 6 μM ...
• TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells

  Bruno Silva, Rajika Arora, Claus M. Azzalin, bioRxiv - Cell Biology 2021

  Quote: ... 2 mM EDTA) and incubated with 2 μg of a rabbit monoclonal anti-HA antibody (Cell Signaling, 3724) for 2 h at room temperature ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK1/2 (Cell Signaling, CST4370), and anti–β-actin (Sigma) ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (#4695S, 1:1000, Cell Signaling), p-STAT3 Y705 (#4370S ...
• Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton

  Wenqing Zhou, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Rac1/2/3 (Cell Signaling 2465S) and secondary antibodies anti-rabbit (ThermoFisher SA5-35571) ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), SOX2 1:100 (R&D AF2018) ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... MEK1/2 1:1000 (Cell Signaling 8727s), and GAPDH 1:10,000 (Sicgen AB0049-20 ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), and Xen1 1:100 (deposited to Developmental Studies Hybridoma Bank (DSHB ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... P44/42 Erk1/2 (#9102, Cell signaling), Phospho-p44/42 MAPK (Erk1/2 ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... Erk-1/2 (Cell Signaling Technology #9102) and β-Actin (Cell Signaling Technology #3700) ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... p-Erk1/2 (Cell Signaling Technology #4377), Erk-1/2 (Cell Signaling Technology #9102 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-ERK1/2 (#9102, Cell Signaling), 1:1000 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-MEK1/2 (#9122, Cell Signaling), 1:1000 ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... Total ERK1/2 (Cell Signaling Technology #4395), 1:1000 ...
• A molecular clock controls periodically driven cell migration in confined spaces

  Sung Hoon Lee, et al., bioRxiv - Systems Biology 2020

  Quote: ... Myosin Light Chain 2 (Cell Signaling, 8505S), mDia1 (Cell Signaling ...
• Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis

  Benjamin Ng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-p-ERK1/2 (4370, Cell Signaling), anti-ERK1/2s (4695 ...
• Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer

  Suzann Duan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COX-2 (1:50, Cell Signaling Technologies), and GAPDH (Cell Signaling Technologies ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-ERK1/2 (4370S, Cell Signaling Technology).
• miR-200 deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts

  Bin Xue, et al., bioRxiv - Cancer Biology 2020

  Quote: ... pErk1/2 pAb (Cell Signaling Technology, 4370), TTF1 (Nkx2.1 ...
• Targeting Chromatin Effector Pygo2 to Enhance Immunotherapy in Prostate Cancer

  Yini Zhu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-Erk1/2 (Cell Signaling Technology, 4370), p53 (Cell Signaling Technology ...
• Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function

  Weiyi Xu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling Technologies, 9102S), anti-LC3B (Cell Signaling Technologies ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (137F5) (Cell Signaling 4695S) lot 28 ...
• Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34⁺ hematopoietic progenitor cells from apoptosis

  Meaghan H. Hancock, et al., bioRxiv - Microbiology 2020

  Quote: ... P-ERK1/2 (Thr202/Tyr204, Cell Signaling), PARP (Cell Signaling) ...
• Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

  Johanna Lilja, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cat. no. 91025, Cell Signaling), phospho-AKT (Ser473 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Erk1/2 (1:1000; L34F12; Cell Signaling), phospho(Ser473)-AKT (1:2000 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MEK1/2 (1:1000; L38C12; Cell Signaling), phospho(Thr44/Tyr42)-ERK1/2 (1:1000 ...
• Taxane chemotherapy leads to breast cancer dormancy escape by stromal injury mediated IL-6/MAP2K signaling

  Ramya Ganesan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit ERK1/2 IgG (Cell Signaling Technology) (cat ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... and phospho-ERK1/2 (Cell Signaling Technology). The protein levels were digitalized using ImageJ 1.48 version (NIH ...
• STAT3 but not STAT5 contributes to the protective effect of electro-acupuncture against myocardial ischemia/reperfusion injury

  Hui-Hui Guo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Bcl-2 (1:1000, Cell Signaling, #3498), Cyt c (1:1000 ...
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti Erk1/2(Cell Signaling Technology, #4695), anti P-selectin (R&D Systems ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... ERK1/2 (Cell Signaling, 9102, 1:2,000), p-ERK1/2 (T202/Y204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MEK1/2 (1:500 Cell Signaling Technology), phospho-ERK1/2 (Thr202/Tyr204 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MEK1/2 (Cell Signaling, 9122, 1:1000), total H3 (Abcam ...
• Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

  Hui Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-ERK1/2 (1:2000, Cell Signaling), and anti-AKT (1:2000 ...
• THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development

  Jiali Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, 4377), anti-phospho-ERK1/2 (Thr202/Tyr204 ...
• Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue

  Megan Moruzzi, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 1:1000 (Cell Signaling, #9102S), α-tubulin (Sigma Aldrich ...
• Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma

  Genshen Zhong, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-MMP-2 (Cell Signaling Technology, #87809), anti-VEGFA (Cell Signaling Technology ...
• Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells

  Wentao Dong, et al., bioRxiv - Biochemistry 2022

  Quote: ... ERK1/2 (Cell Signaling, Cat. No. 9102) phospho-ERK1/2 (Cell Signaling ...
• Cellular protection from H₂O₂ toxicity by Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase

  Chris Hino, et al., bioRxiv - Cell Biology 2023

  Quote: ... and polyclonal Nrf 2 (Cell Signaling 336495). All antibodies were used at 1:1000 dilution in blocking buffer ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2 μg FOXM1 antibody (Cell Signaling, 20459) was then added and incubated at 4 °C overnight on a rotating platform ...
• Nischarin negatively impacts ShcD-mediated tumor cell migration

  Rayan A. Hago, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (cst4695-Cell Signaling, USA), anti-Nischarin (ab204588-Abcam ...
• PML mutants resistant to arsenic induced degradation fail to generate the appropriate SUMO and ubiquitin signals required for RNF4 and p97 recruitment

  Ellis G. Jaffray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-SUMO- 2 (Cell signaling 4971S), rabbit FK2 ubiquitin (Enzo BML-PW8810-0500) ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pERK1/2 (1:1,000; Cell Signaling, #9101), ERK1/2 (1:1,000 ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:1,000; Cell Signaling, #4695), pAKT (Thr308 ...