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2351 - 2400 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

  Tamara Rothenburger, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... γH2AX (Cell Signaling, 9718S, 1:1000), Chk2 (Cell Signaling ...
• Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

  Tamara Rothenburger, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Chk2 (Cell Signaling, 2662S, 1:1000), pChk2 (Cell Signaling ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atg101 (1:1000, Cell Signaling, #13492), ULK1 (1:1000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... ULK1 (1:1000, Cell Signaling, #8054), β III tubulin (Tuj1 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... FIP200 (1:1000, Cell Signaling, #12436), Atg101 (1:1000 ...
• Design of Biologically Active Binary Protein 2D Materials

  Ariel J. Ben-Sasson, et al., bioRxiv - Synthetic Biology 2020

  Quote: ... β-Actin (Cell Signaling 13E5, 1:1000). The membrane incubated with P-AKT was then blocked with 5% milk prior to secondary antibody incubation ...
• Gα13 loss promotes tumor progression in the KPC transgenic mouse model of advanced pancreatic cancer

  Mario A. Shields, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MTOR (Cell Signaling #2983, 1:500), and RPS6 (Cell Signaling #2217 ...
• The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferons by engaging cytosolic DNA sensing in macrophages

  Krystal J Vail, et al., bioRxiv - Immunology 2021

  Quote: ... IRF3 1:1000 (Cell Signaling 4302), pIRF3 Ser396 1:1000 (Cell Signaling 4947) ...
• The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferons by engaging cytosolic DNA sensing in macrophages

  Krystal J Vail, et al., bioRxiv - Immunology 2021

  Quote: ... STAT1 1:1000 (Cell Signaling 9172S), pSTAT1 Tyr701 1:1000 (Cell Signaling 9177S) ...
• Selenium-dependent metabolic reprogramming during inflammation and resolution

  Arvind M. Korwar, et al., bioRxiv - Immunology 2021

  Quote: ... anti-pPkm (Cell Signaling: 1: 10,000), anti-Shpk (Carkl ...
• Selenium-dependent metabolic reprogramming during inflammation and resolution

  Arvind M. Korwar, et al., bioRxiv - Immunology 2021

  Quote: ... anti-Pkm (Cell Signaling; 1:10,000), anti-pPkm (Cell Signaling ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Bid (Cell Signaling, 1/1000), anti-Bad (Santa Cruz Biotechnology ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... MLKL (1:1000, #28640, Cell signaling); Pho-p53-S15 (1:1000 ...
• Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

  Yujia Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... CDH1 (1:500, 3195S, Cell Signaling), SLC12A1 (1:200,18970-1-AP ...
• WNT4 and WNT3A activate cell autonomous Wnt signaling independent of PORCN and secretion

  Deviyani M. Rao, et al., bioRxiv - Cell Biology 2019

  Quote: ... DVL3 (Cell Signaling, 3218, 1:2,000), pLRP6 (s1490 ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... IκBα (1:1000; Cell Signaling #4814), NF-κB1 p105/p50 (1:1000 ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... RELB (1:1000; Cell Signaling #10544), Histone H3 (1:10,000 ...
• Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66-independent targeting of NogoA

  Cheng Yung Lin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Cofilin (Cell Signaling; CS; 1:1000), phosphorylated Cofilin at S3 (CS ...
• SOX9 acts as a dynamic pioneer factor inducing stable changes in the chromatin landscape to reprogram endothelial cells

  Bettina M. Fuglerud, et al., bioRxiv - Genomics 2021

  Quote: ... VIM (1:50, 5741S, Cell Signaling), POSTN (1:50 ...
• IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

  Wei Wang, et al., bioRxiv - Genetics 2020

  Quote: ... F4/80 (1:400; Cell Signaling) and P-ERK (1:200 ...
• Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

  Julia Noack, et al., bioRxiv - Cell Biology 2020

  Quote: ... CHOP 1:500 (Cell Signaling Technology), ATF4 1:1000 (Cell Signaling Technology) ...
• Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

  Julia Noack, et al., bioRxiv - Cell Biology 2020

  Quote: ... ATF4 1:1000 (Cell Signaling Technology), HSP60 1:20000 (Proteintech) ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... pMEK (Cell Signaling 9121, 1:1000), Ub (P4D1 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... pAKT (Cell Signaling 4060, 1:1000), MEK (Cell Signaling 9122 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... AKT (Cell Signaling 9272, 1:1000), pAKT (Cell Signaling 4060 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... YFP (Cell Signaling 2956, 1:100), Slug (Cell Signaling 9585 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... MEK (Cell Signaling 9122, 1:1000), pMEK (Cell Signaling 9121 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... Slug (Cell Signaling 9585, 1:100), acetylated-tubulin (Cell Signaling 5335 ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... GAPDH (Cell Signaling, 5174, 1:2,000), IGF2 (ABclonal ...
• Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase

  David C. Hughes, et al., bioRxiv - Physiology 2020

  Quote: ... α-actinin (1:1000, Cell Signaling, 3134), Vimentin (1:1000 ...
• Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase

  David C. Hughes, et al., bioRxiv - Physiology 2020

  Quote: ... Desmin (1:500, Cell Signaling, 5332), Dystrophin (1:1000 ...
• Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

  MA Jiajia, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:100 (#9102, Cell Signaling Technology), Rabbit anti-p90RSK (Phospho-Thr348) ...
• In vivo progressive degeneration of Huntington’s disease patient-derived neurons reveals human-specific pathological phenotypes

  Andrés Miguez, et al., bioRxiv - Neuroscience 2020

  Quote: ... DARPP-32 (1:500, Cell Signaling), DARPP-32 (1:1000 ...
• Transcriptional Control of Brain Tumour Stem Cells by a Carbohydrate Binding Protein

  Ahmad Sharanek, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GAPDH (1:1000, Cell Signaling, #2118), STAT3 (1:1000 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... JNK (Cell Signaling, 9252s, 1:1000), Phospho-p38 MAPK (Cell Signaling ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GAPDH (Cell Signaling, 2118L, 1:2000), HRP-conjugated secondary antibodies (Santa Cruz Biotechnology ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... AXL (Cell Signaling, 8661s, 1:1000), Cleaved PARP (Cell Signaling ...
• Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs

  A. Lumeau, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GAPDH (Cell signaling #5174, 1:5000), actin β (santa cruz sc-47778 ...
• Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs

  A. Lumeau, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Chk1 (Cell signaling #2360, 1:1000), CDA (abclonal A13959 ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... Rab11 (#5589S, 1:1000, Cell Signaling), Rab7 (#9367S ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... Rab7 (#9367S, 1:1000, Cell Signaling), p-EGFR Y1068 (#3777S ...
• Intermediate Progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants

  Carrie M. Spratford, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbitαPH3 (1:1000, Cell Signaling #97015), mouseαP1 (1:100 ...
• Intermediate Progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants

  Carrie M. Spratford, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbitαdpERK (1:100, Cell Signaling #4370), and αL1 (1:10 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... p-eIF2α (1:1000, Cell Signaling), eIF2α (1:1000 ...
• SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

  Ambra Cappelletto, et al., bioRxiv - Pathology 2021

  Quote: ... tubulin (Cell Signaling, #3873S; 1:10,000) and TMEM16F (Sigma-Aldrich ...
• Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells

  Sunday Okutachi, et al., bioRxiv - Biochemistry 2021

  Quote: ... ERK 1:1000 (Cell Signaling, 9102). A mouse antibody against GAPDH 1:2000 (Sigma ...
• SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

  Yen K. Lieu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-GATA-1 (Cell Signaling, 3535T), anti-p-HSP27 (Cell Signaling ...
• Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth

  Abigail S. Krall, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ATF4 (Cell Signaling 11815, 1:500), phospho-T389 S6 kinase (Cell Signaling 9234 ...
• Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth

  Abigail S. Krall, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CAD (Cell Signaling 11933, 1:1000), and a-tubulin (Sigma T6074 ...
• Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naïve Pluripotency

  Jonathan Bayerl, et al., bioRxiv - Developmental Biology 2020

  Quote: ... TFAP2C (CSTH2320, 1:1000, Cell Signaling), STAT3 (sc-7993 ...