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2051 - 2100 of 10000+ citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Reprogramming Alveolar Macrophage Responses to TGF-β Reveals CCR2⁺ Monocyte Activity that Promotes Bronchiolitis Obliterans Syndrome

  Zhiyi Liu, et al., bioRxiv - Immunology 2022

  Quote: ... 1:1000 (Cell Signaling Technology). Mouse-anti human CD8α (C8/114B) ...
• EPSTEIN-BARR VIRUS LMP1 ENHANCES LEVELS OF MICROVESICLE-ASSOCIATED PD-L1

  Monica Abou Harb, Li Sun, David G. Meckes Jr., bioRxiv - Microbiology 2022

  Quote: ... Caveolin-1 (D46G3; Cell Signaling), CD63 (TS63 ...
• Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjögren’s syndrome

  Jimin Yoon, et al., bioRxiv - Molecular Biology 2022

  Quote: ... ZO-1 (Cell Signaling Technology), and AQP5 (Cell Signaling Technology ...
• Short-term and bystander effects of radiation on murine submandibular glands

  Hitoshi Uchida, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Nkcc1 (Cell Signaling, 1:1000), ZO-1 (Thermo Fisher Scientific ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pAKT308 (Cell Signaling; 1:1000); pAKT473 (Fluidigm ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ß-actin (Cell Signaling; 1:1000).
• Epoxy fatty acid dysregulation and neuroinflammation in Alzheimer’s disease is resolved by a soluble epoxide hydrolase inhibitor

  Anamitra Ghosh, et al., bioRxiv - Neuroscience 2020

  Quote: ... iNOS (1:1000, Cell signaling); GFAP (1:15000 ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... PPARγ (Cell Signaling; 1:1000), SCD-1 (Cell Signaling ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... p65 (Cell Signaling; 1:1000), phospho-p65 (serine536 ...
• A network of DZF proteins controls alternative splicing regulation and fidelity

  Nazmul Haque, et al., bioRxiv - Molecular Biology 2022

  Quote: ... β-actin (Cell Signaling, 1:1000). Fluorescently labeled secondary antibodies (ThermoFisher Scientific ...
• Phosphorylation and ubiquitination independent endocytosis of BRI1

  Lucas Alves Neubus Claus, et al., bioRxiv - Plant Biology 2022

  Quote: ... α-pThr (1/2,000; Cell Signaling), α-BES1 (Yin et al. ...
• Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

  Rocío G. Sampayo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... SMAD5 (Cell Signaling, 1:1000). Horseradish-peroxidase conjugated secondary antibodies (Sigma-Aldrich ...
• Computer Designed PRC2 Inhibitor, EBdCas9, Reveals Functional TATA boxes in Distal Promoter Regions

  Shiri Levy, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Cas9 (Cell Signaling 1:1000), Oct-4 (Santa Cruz sc-5279 ...
• 14-3-3ζ mediates an alternative, non-thermogenic mechanism to reduce heat loss and improve cold tolerance

  Kadidia Diallo, et al., bioRxiv - Physiology 2020

  Quote: ... β-Tubulin (1:1000, Cell Signaling) and Tyrosine hydroxylase (1:1000 ...
• 14-3-3ζ mediates an alternative, non-thermogenic mechanism to reduce heat loss and improve cold tolerance

  Kadidia Diallo, et al., bioRxiv - Physiology 2020

  Quote: ... β-Actin (1:10000, Cell Signaling), β-Tubulin (1:1000 ...
• PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR

  Allen T. Yu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... TIAR (1:1000; Cell Signaling). IRDye-800CW was used as a fluor for secondary anti-rabbit antibodies ...
• The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferons by engaging cytosolic DNA sensing in macrophages

  Krystal J Vail, et al., bioRxiv - Immunology 2021

  Quote: ... 1:1000 (Cell Signaling 3033S), STAT1 1:1000 (Cell Signaling 9172S) ...
• Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells

  Ritusree Biswas, et al., bioRxiv - Cell Biology 2020

  Quote: ... YAP1 (1:100) (Cell Signaling), TAZ (1:100 ...
• IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

  Wei Wang, et al., bioRxiv - Genetics 2020

  Quote: ... PCNA (1:300; Cell Signaling), CK19 (1:200 ...
• Single Cell atlas of uterine myometrium and leiomyomas reveals diverse and novel cell types of non-monoclonal origin

  Jyoti Goad, et al., bioRxiv - Genetics 2020

  Quote: ... PDPN (1:200, Cell signaling), overnight at 4°C ...
• In vivo progressive degeneration of Huntington’s disease patient-derived neurons reveals human-specific pathological phenotypes

  Andrés Miguez, et al., bioRxiv - Neuroscience 2020

  Quote: ... NeuN (1:500, Cell Signaling), Neuropeptide Y (1:300 ...
• Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

  Deborah Fanfone, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MCL-1 (Cell Signaling, 4572S), PARP-1 (Cell Signaling ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... DRP-1 (Cell signaling, #8570), p-DRP-1 (S616 ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... SOD-1 (Cell signaling, #2770), SOD-2 (Enzo Life Sciences ...
• The IgG3 Subclass of β1-adrenergic receptor autoantibody is an endogenous biaser of β1AR signaling

  Maradumane L. Mohan, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... α-pERK (Cell Signaling, 1:2000), α-ERK (Cell Signaling ...
• The IgG3 Subclass of β1-adrenergic receptor autoantibody is an endogenous biaser of β1AR signaling

  Maradumane L. Mohan, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... α-ERK (Cell Signaling, 1:2000), α-pβ2AR (Santacruz Biotechnology ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (1:1000, Cell Signaling), ATF4 (1:1000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... PARP (1:2000, Cell Signaling), LC3B (1:2000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... α-tubulin (1:2000, Cell Signaling), and β-actin (1:2500 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... ATF4 (1:1000, Cell Signaling), TFEB (1:1000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... α-synuclein (1:2000, Cell Signaling), α-tubulin (1:2000 ...
• Temporally-precise basolateral amygdala activation is required for the formation of taste memories in gustatory cortex

  Elor Arieli, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:1000 (Cell Signaling, 8889S) and with DAPI 1:1000 in block for 3h at room temperature ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... Beclin-1 (Cell signaling, #3738), mitofusin 2 (Cell signaling ...
• Deletion of the AMPylase mFICD alters cytokine secretion and affects cognitive plasticity in vivo

  Nicholas McCaul, et al., bioRxiv - Molecular Biology 2021

  Quote: ... XBP-1 (Cell Signaling Technology), PERK (Santa Cruz) ...
• Argonaute Binding within Human Nuclear RNA and its Impact on Alternative Splicing

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (2433, Cell Signaling), anti-LaminA/C ...
• Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

  Kai P. Hoefig, et al., bioRxiv - Immunology 2020

  Quote: ... (1:1000, 8776, Cell Signaling), anti-β- tubulin ...
• Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

  Kai P. Hoefig, et al., bioRxiv - Immunology 2020

  Quote: ... (1:1000, 86298, Cell Signaling). Proteins were visualized by staining with anti-rat (1:3000 ...
• GOLIATH regulates LDLR availability and plasma LDL cholesterol levels

  Bethan L. Clifford, et al., bioRxiv - Molecular Biology 2020

  Quote: ... PDI (1:1,000; Cell Signaling), and Transferrin Receptor (1:1,000 ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pGSK3ß (Cell Signaling; 1:500), Total GSK3ß (Cell Signaling ...
• Argonaute Binding within 3’-Untranslated Regions Does Not Predict Gene Repression

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1:20000 (2650S, Cell Signaling).
• Argonaute Binding within 3’-Untranslated Regions Does Not Predict Gene Repression

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1:1000 (2433S, Cell Signaling), anti-LaminA/C ...
• HES1 is a Critical Mediator of the SHH-GLI3 Axis in Regulating Digit Number

  Deepika Sharma, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CCND1 (1:1000; Cell Signaling), LMNA (1:1000 ...
• Mitochondrial dysfunction promotes alternative gasdermin D-mediated inflammatory cell death and susceptibility to infection

  Chi G. Weindel, et al., bioRxiv - Immunology 2021

  Quote: ... DRP1 (Cell Signaling, 1:1000); pDRP1 Ser616 (Cell Signaling ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... PDX1 (Cell Signaling 1:1000), BclXL (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... PTEN (Cell Signaling 1:1000), pAKT (Cell Signaling ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... BclXL (Cell Signaling 1:1000), HSP90 (Santa Cruz 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p27 (Cell Signaling 1:1000), PTEN (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... pAKT (Cell Signaling, 1:1,000), AKT (Cell Signaling 1:1,000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... SKP2 (Cell Signaling 1:1000), p57 (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p21 (Cell Signaling 1:1000), p27 (Cell Signaling 1:1000) ...