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1551 - 1600 of 4006 citations for 2 Amino 6 chloro 9 3 5 di O p toluoyl beta D 2 deoxyribofurnanosyl purine since 2020

• Phase diversity-based wavefront sensing for fluorescence microscopy

  Courtney Johnson, et al., bioRxiv - Bioengineering 2024

  Quote: ... and Rabbit anti Phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling Technology, 3674), both at 1:200 dilution in PBS containing 1% BSA ...
• Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons

  Nicholas L. Truex, et al., bioRxiv - Immunology 2023

  Quote: ... Primary and secondary antibodies for visualization of the bands include: Erk1/2 (Cell Signaling), goat anti-mouse IRdye680 (LI-COR Biosciences) ...
• Myc controls IL-15-driven expansion and translational machinery of NK cells

  Hanif J. Khameneh, et al., bioRxiv - Immunology 2022

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204; D13.14.4E; XP Rabbit mAb #4370; Cell Signaling, 1:150).
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-ERK 1/2 Y202/204 1:2000 (Cell Signaling Technology Cat# 4370, RRID:AB_2315112), ERK 1:1000 (Cell Signaling Technology Cat# 4695 ...
• Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

  Christine Chiasson-MacKenzie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho p44/42 (ERK1/2) rabbit mAb (1:1000; D13.14.4E, Cell Signaling Technology); anti-p44/42 (ERK1/2 ...
• In Vitro Validation of Computationally Predicted Oncogenic Driver Mutations in EGFR Tyrosine Kinase Domain

  Vidya P Warrier, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK1/2 and the appropriate secondary antibodies were purchased from Cell Signaling or Santa Cruz Biotechnology ...
• The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death

  Jennifer Galdieri, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (Cell Signaling, 4370) diluted at 1:200.
• Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala

  Dipan C. Patel, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit polyclonal anti-α-tubulin antibody (2 µg/ml; 2144, Cell Signaling Technology) overnight at 4 °C ...
• Tumor suppressor let-7 acts as a key regulator for maintaining pluripotency gene expression in Muse cells

  Gen Li, Shohei Wakao, Masaaki Kitada, Mari Dezawa, bioRxiv - Cell Biology 2023

  Quote: ... Phospho-p44/p42 MEK/ERK (ERK1/2; Thr202/Tyr 204) (1:1000, Cell Signaling), p44/p42 MEK/ERK (ERK1/2 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:30, Cell Signaling Technology), anti-Hrs (sc-271455 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:1000, Cell Signaling Technology), Phospho-p44/42 MAPK (Erk1/2 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) and chicken antityrosine hydroxylase (1:2000 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) antibody in PBS with 0.3% Triton-X for 2h at room temperature ...
• E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes

  Chaoyu Fu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 (Ser19) antibody (3671, Cell Signaling Technologies, diluted 1:50) according to the manufacturer’s instructions ...
• Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice

  Emma Sailor-Longsworth, et al., bioRxiv - Neuroscience 2024

  Quote: ... or antibody anti-pERK1/2 (Thr202/Tyr204, 1:400 dilution, 9101, Cell Signaling Technology) and imaged with a confocal microscope (LSM 700 ...
• Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery

  Taylor E. Escher, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti–Phospho-p44/42 MAPK (pERK1/2; Cell Signaling Technology, catalog no. 4377, RRID:AB_331775), anti-p44/42 MAPK (ERK1/2 ...
• Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing

  K. Yu. Vlasova, et al., bioRxiv - Bioengineering 2024

  Quote: ... cycle 2 Rabbit E-Cadherin (Cell Signaling, 24E10 #3195, dilution 1:200, 1 h), cycle 3 Rabbit CD31 (Abcam ...
• Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

  Pirunthan Perampalam, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK(Erk1/2) T202/Y204 (Cell Signaling Technology; rabbit antibody #4370), p38 MAPK (Cell Signaling Technology ...
• Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury

  Yifan Yuan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Thr18/Ser19 Phospho-Myosin Light Chain 2 (#3674) from Cell Signaling Technology (Danvers); ICAM-1 (Santa Cruz Biotechnologies ...
• Positional information drives distinct traits in transcriptomically identified neuronal types

  Inbal Shainer, et al., bioRxiv - Neuroscience 2024

  Quote: ... fixed in 4% PFA and immunostained with Mouse anti-ERK1/2 (Cell Signaling Technology) and Chicken anti-GFP (Invitrogen) ...
• Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model

  Christopher D. Balak, et al., bioRxiv - Neuroscience 2024

  Quote: ... 2 μg each of two TFEB antibodies (Abcam ab2636, Cell Signaling CST 37785 (D2O7D), or 2 μg each of two TFE3 antibodies (Abcam ab93808 ...
• A spreading, multi-tissue wound signal initiates whole-body regeneration

  Catriona Breen, Mansi Srivastava, bioRxiv - Developmental Biology 2024

  Quote: ... Primary antibodies used are as follows: rabbit anti-pERK1/2 (Cell Signaling Technology 4370) 1:100 ...
• Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio

  Katherine R. Ferrick, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit phospho-MAPK1/2(Thr202/Tyr204)(1:400, Cell Signaling Technology Cat#4370, RRID:AB_2315112), mouse phospho-S6(235/236)(1:800 ...
• Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

  Yuma Cho, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phosoho-Myosin Light Chain 2 (Thr18/Thr19) mAb (95777; Cell Signaling Technology); rabbit anti-TROP2 mAb (ab214488 ...
• PCDHGC3 silencing promotes clear cell renal cell carcinoma metastasis via mTOR/HIF2α and lipid metabolism reprogramming

  Lucía Celada, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (#9101 Cell Signaling Technology) at 1:1,000 dilution ...
• Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

  Mary C. Rominger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) 1:1000 (Thr202/Tyr204) (Cell Signaling Technology, 4370), AKT 1:1000 (Cell Signaling Technology ...
• Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer

  Ya-Yun Cheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and incubated with blocking buffer containing 2% goat serum/PBS (Cell Signaling Technology, 5425) for 30 mins at room temperature ...
• Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

  Zhe Ji, et al., bioRxiv - Cell Biology 2024

  Quote: ... cells were incubated with 2 ng/mL TGF-β3 (Cell signaling #8425 and #10858) or 20 ng/mL BMP-4 (Peprotech 120-05 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: p44/42 MAPK (Erk1/2) (3A7) Mouse mAb (Cell Signaling Technology, cat. no. 9107)
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology, cat. no. 9154) c-Raf (D4B3J ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology), Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) were diluted in Intercept PBS Block Buffer (LicorBio ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Aging-associated changes in transcriptional elongation influence metazoan longevity

  Cédric Debès, et al., bioRxiv - Genomics 2022

  Quote: ... Senescence state was monitored by Beta-galactosidase staining (88) in different passages (Cell Signaling Technology, Senescence β-Galactosidase Staining Kit ...
• Molecular basis for substrate recruitment to the PRMT5 methylosome

  Kathleen M. Mulvaney, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 2.8mg total protein for each sample was digested with trypsin and purified over C18 columns for enrichment with the Symmetric Di-Methyl Arginine Motif Antibody (Cell Signaling #13563). Enriched peptides were purified over C18 STAGE tips46 ...
• An atypical E3 ligase safeguards the ribosome during nutrient stress

  Todd Douglas, et al., bioRxiv - Cell Biology 2024

  Quote: The enrichment of di-Gly peptides was performed using PTMScan® HS Ubiquitin/SUMO Remnant Motif (K-GG) Kit (Cell Signaling Technology) as previously described99 ...
• A Rab Escort Protein Regulates the MAPK Pathway That Controls Filamentous Growth in Yeast

  Sheida Jamalzadeh, Paul J. Cullen, bioRxiv - Genomics 2020

  Quote: Phosphorylation of mating and fMAPK pathways (P∼Kss1 and P∼Fus3) was investigated with p44-42 antibody (Cell Signaling Technology, Danvers, MA, 4370) at a dilution of 1:10000 to detect ERK-type MAP kinases ...
• Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

  Stewart W.C. Masson, et al., bioRxiv - Systems Biology 2023

  Quote: ... phosphorylated GSK-3α/β S21/9 (Cell Signaling Technologies #9327; diluted 1:1000), GSK3α/β (Cell Signaling Technologies #5676 ...
• TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

  Thomas G. Scott, et al., bioRxiv - Genomics 2023

  Quote: ... 1ml (5*106 cells) was aliquoted into each of 3 tubes with antibody (1.25 µg anti-HA, Cell Signaling #3724S ...
• The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

  Joelle Lo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Cells were rinsed 3 times with PBS for 5 minutes before adding fluorescent secondary antibody (Cell Signaling Technology 4413S) diluted 1:2000 in PBS containing 1% BSA and 0.1% Triton-X at 37°C for 25 minutes ...
• Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

  Olga Gewartowska, et al., bioRxiv - Genetics 2020

  Quote: ... Incubation with primary anti-calreticulin antibody (Cell signaling #12238; 1:600; O/N; 4 °C, wet chamber) and secondary goat anti-rabbit HRP conjugated antibody (Agrisera ...
• Coordination of transcriptional and translational regulations in human epithelial cells infected by Listeria monocytogenes

  Vinko Besic, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-eIF2α (Ser51) clone D9G8 #3398) or mouse monoclonal antibodies (eIF2α clone D-3, Santa Cruz #sc-133132, β-Actin clone E4D9Z, Cell Signaling Technology #58169 ...
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following primary antibodies were used for protein immunoblots: Anti p-Tyr (4G10, Millipore Sigma, #05-321 and P-Tyr-1000, Cell Signaling Technology, #8954), anti V5-HRP (ThermoFisher Scientific ...
• Enabling non-viral DNA delivery using lipid nanoparticles co-loaded with endogenous anti-inflammatory lipids

  Manthan N. Patel, et al., bioRxiv - Bioengineering 2024

  Quote: ... cells were treated with 1:150 primary antibodies (anti p-STING, 62912S, Cell Signaling Technology Inc.; anti p-TBK1, 5483S, Cell Signaling Technology Inc.) at 4°Covernight ...
• Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord reproducibly models early events in ERK-mediated tumorigenesis

  Axelle Wilmerding, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) 1:250 (Cell signaling #9101), rabbit anti-SOX2 1:500 (AB5603 Merck Millipore) ...
• MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

  Carolyn Sangokoya, Robert Blelloch, bioRxiv - Developmental Biology 2020

  Quote: ... Phospho-p44/42 Erk1/2 Thr202/Tyr204 at 1:1000 dilution (Cell Signaling Technology, 4370), and p44/42 Erk1/2 at 1:1000 dilution (Cell Signaling Technology ...
• Surface-associated antigen induces B-cell permeabilization and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

  Fernando Y. Maeda, et al., bioRxiv - Cell Biology 2021

  Quote: ... and incubated with rabbit anti-phosphorylated myosin light chain 2 (pMLC2) antibodies (Cell Signaling Technology) to label activated NMII (Bresnick 1999) ...