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1451 - 1500 of 4006 citations for 2 Amino 6 chloro 9 3 5 di O p toluoyl beta D 2 deoxyribofurnanosyl purine since 2020

• Internalized β2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling

  Wenhui Wei, Alan V. Smrcka, bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... rabbit anti-p-ERK (Cell Signaling Technology, Cat# 4370S), mouse anti-t-ERK (Cell Signaling Technology ...
• Association of NOTCH3 with Elastic Fiber Dispersion in the Infrarenal Abdominal Aorta of Cynomolgus Monkeys

  Sohei Ito, et al., bioRxiv - Pathology 2023

  Quote: ... p-ERK (0.1 µg/mL, 9101S, Cell Signaling Technology), ERK (0.1 µg/mL ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... P(S240-244)-rpS6 (1:1000, Cell signaling 2215S), GRSF1 (1:1000 ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... p-Akt Thr 308 (Cell Signaling, #2965, 1:1000), p38 (Cell Signaling ...
• Fluoxetine treatment during postnatal and juvenile temporal epochs evokes diametrically opposing changes in anxio-depressive behaviors, gene expression, mitochondrial function, and neuronal architecture in the medial prefrontal cortex

  Utkarsha Ghai, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit p-70 S6K (1:1000, Cell Signaling Technologies), rabbit phosphorylated p-70 S6K (1:250 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... p-S757-ULK (1:500; Cell Signaling Technology #5869S), ULK (1:500 ...
• Nerve Growth Factor Receptor Limits Inflammation to Promote Remodeling and Repair of Osteoarthritic Joints

  Lan Zhao, Yumei Lai, Hongli Jiao, Jian Huang, bioRxiv - Cell Biology 2023

  Quote: ... 1/100 anti-p-SMAD1 (Cell Signaling, catalog # 9516S), 1/200 anti-SMAD1 (abcam ...
• Caspase-8-mediated CYLD Cleavage boosts LPS-induced Endotoxic Shock

  Jianling Liu, et al., bioRxiv - Immunology 2024

  Quote: ... p-IKKα/β (1:2000, Cell Signaling Technology, 2697S), IKKα (1:2000 ...
• Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

  Sanchita Mishra, et al., bioRxiv - Immunology 2024

  Quote: ... anti-p-MLKL (Cell Signaling Technology, 91689, Human-specific), anti-RIPK3 (Cell Signaling Technology ...
• Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

  Sanchita Mishra, et al., bioRxiv - Immunology 2024

  Quote: ... anti-p-MLKL (Cell Signaling Technology, 37333, Mouse-specific), anti-p-MLKL (Cell Signaling Technology ...
• Microglial 25-hydroxycholesterol mediates neuroinflammation and neurodegeneration in a tauopathy mouse model

  Danira Toral-Rios, et al., bioRxiv - Neuroscience 2023

  Quote: ... p-STAT3 (rabbit polyclonal, 1:500; Cell Signaling, 9145S), p-p65 NF-kB (rabbit polyclonal ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... p-T308 AKT (1:1,000; Cell Signaling Technology # 2965), AKT (1:1,000 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... p-p70 S6K1 (1:500; Cell Signaling Technology #9234L), S6K (1:1,000 ...
• Oolonghomobisflavans from Camellia sinensis disaggregate tau fibrils across Alzheimer’s disease models

  Chatrawee Duangjan, et al., bioRxiv - Physiology 2024

  Quote: ... P-tau S416 clone D7U2P (Cell Signaling, 1:1000), pan-tau (Millipore Sigma ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... Cells were incubated with p-ACC antibody (Cell Signaling) then probed with goat anti-rabbit IgG-Alexa Fluor 488 ...
• ATAD1 and the integrated stress response prevent clogging of TOM and damage caused by un-imported mitochondrial proteins

  John Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-p-eIF2α (1:500, Cell Signaling Technology), mouse anti-HA (1:1000 ...
• Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice.

  Diego Acuna-Catalan, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti p-PKA substrates (RRXS*/T*) (#9624 Cell signaling) and anti GAPDH (#MAB374 Merck) ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... P-AKT(Ser473) (1:1000; Cell Signaling Technology, #4051), P-AKT(Ser473 ...
• Multilevel regulation of NF-κB signaling by NSD2 suppresses Kras-driven pancreatic tumorigenesis

  Wenxin Feng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-IKKα/β(Ser176/180) (Cell Signaling Technology, 2697).
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... P-AKT(Thr308) (1:1000; Cell Signaling Technology, #2965), NT5E (1:1000 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... P-AKT(Ser473) (1:1000; Cell Signaling Technology, #4060), P-AKT(Thr308 ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-p-p38 (Cell Signaling, USA, 1:500 dilution), anti-p-JNK (Cell Signaling ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-p-JNK (Cell Signaling, USA, 1:500 dilution), anti-ERK1/2 (Cell Signaling ...
• Cell-intrinsic ceramides determine T cell function during melanoma progression

  Matthias Hose, et al., bioRxiv - Immunology 2022

  Quote: ... anti-p-ZAP70 (Cell Signaling, Frankfurt am Main, Germany), anti-Granzyme B (Invitrogen ...
• Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency

  Nazli Khodayari, et al., bioRxiv - Cell Biology 2022

  Quote: ... p-Ikkβ and β-actin (Cell Signaling, Danvers, MA), Calnexin ...
• Depletion of ALMS1 affects TGF-β signalling pathway and downstream processes such as cell migration and adhesion capacity

  Brais Bea-Mascato, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti p-SMAD2 (1:1000, Cell Signaling Technology, 3101).
• Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling

  David M. Walter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and p-H3 (Cell Signaling Technology, cs9701, 1:500) were performed after citrate-based antigen retrieval ...
• Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells

  Haymar Wint, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti P-cadherin (12H6, Cell Signaling Technology), mouse monoclonal anti VE- cadherin (610251 ...
• IL-2 secreting T helper cells promote EF B cell maturation via intrinsic regulation of B cell mTOR/AKT/Blimp-1 axis

  Caterina E. Faliti, et al., bioRxiv - Immunology 2022

  Quote: ... Primary antibody against p-S6 (Cell Signaling, Catalog #4858) and pAKT (Cell Signaling ...
• Immunosuppressive tocilizumab prevents astrocyte induced neurotoxicity in hiPSC-LRRK2 Parkinson’s disease by targeting receptor interleukin-6

  Meritxell Pons-Espinal, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-P-STAT3 (Tyr705) (Cell Signaling #9145, D3A7), rabbit anti-STAT3 (Cell Signaling #12640 ...
• Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

  Kerstin Voelkl, et al., bioRxiv - Neuroscience 2023

  Quote: ... and mouse anti-p-ERK (Cell Signaling Technology, 9106). The next day ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-p-YAP (1:500, Cell Signaling, #4911), rabbit anti-YAP (1:500 ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-p-AKT (1:1000, Cell Signaling, #4051), rabbit anti-AKT (1:1000 ...
• Liraglutide protects against diastolic dysfunction and improves ventricular protein translation

  Cody Rutledge, et al., bioRxiv - Physiology 2023

  Quote: ... p-4EBP1 (Thr37/46, 1:1000, Cell Signaling, #2855), 4EBP1 (1:1000 ...
• Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

  Chunsong Yang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-STAT1(Tyr701)(1:1,000, rabbit, Cell Signaling 9171), LAMIN A/C (1:40 ...
• Progressive Senescence Programs Induce Intrinsic Vulnerability to Aging-related Breast Cancer

  Huiru Bai, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Rb anti-p-IKKα/β (Cell signaling technology, 2697), Rb anti-p-p65 (Cell signaling technology ...
• PIM kinase control of CD8 T cell protein synthesis and cell trafficking

  Julia M Marchingo, et al., bioRxiv - Immunology 2024

  Quote: ... S6K p-T389 (108D2, Cell Signaling Technology, cat# 9234S), STAT5 p-Y694 (C11C5 ...
• Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4⁺ T Cell Function and Oxidative Metabolism

  KayLee K. Steiner, et al., bioRxiv - Immunology 2024

  Quote: ... P-S6 PE (1:100 Cell Signaling Technologies, 5316S), Propidium Iodide (Sigma ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-AKT (Thr308; 1:1000; Cell Signaling Technology; #2965), ERK (1:1000 ...
• β-aminopropionitrile Induces Distinct Pathologies in the Ascending and Descending Thoracic Aortic Regions of Mice

  Michael K. Franklin, et al., bioRxiv - Pathology 2024

  Quote: ... p-ERK (0.1 µg/mL, 9101S, Cell Signaling Technology), ERK (0.1 µg/mL ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p-STING (Cell Signaling Technology, 19781S, 1:1000), anti-TBK1 (Proteintech ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p-TBK1 (Cell Signaling Technology, 5483S, 1:1000), anti-IRF3 (Proteintech ...
• Reduced SH3RF3 may protect against Alzheimer’s disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling

  Ronak Patel, et al., bioRxiv - Neuroscience 2024

  Quote: ... phospho-p-50/p105 (1:1000; Cell Signaling Technologies), total p50/p105(1:1000 ...
• ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke

  Xianshu Ju, et al., bioRxiv - Neuroscience 2024

  Quote: ... phosphorylated-Eif2α (p-Eif2α; Cell Signaling Technology, CAT#3398), Eif2α (Cell Signaling Technology ...
• Regulation of intracellular cAMP levels in osteocytes by mechano-sensitive focal adhesion kinase via PDE8A

  Garyfallia Papaioannou, et al., bioRxiv - Molecular Biology 2024

  Quote: ... p- FAK(Y397) (1:500, Cell Signaling Technology, 8556), beta-tubulin (1:250 ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... P-PAK1(Ser144) (1:1000, #2606, Cell Signaling Technology), PDGFRα (1:1000 ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... P-PAK1(Ser144) (1:100, #2606, Cell Signaling Technology), PDGFRα (1:100 ...
• The novel role of Kallistatin in linking metabolic syndromes and cognitive memory deterioration by inducing amyloid-β plaques accumulation and tau protein hyperphosphorylation

  Weiwei Qi, et al., bioRxiv - Neuroscience 2024

  Quote: ... p-GSK3β Ser9 (#9323, Cell Signaling Technology, Boston, USA), β-actin (A5441-2ml ...
• MITOCHONDRIAL ANTIVIRAL PATHWAYS CONTROL ANTI-HIV RESPONSES AND ISCHEMIC STROKE OUTCOMES VIA THE RIG-1 SIGNALING AND INNATE IMMUNITY MECHANISMS

  Silvia Torices, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-p-TBK (Ser 172) (Cell Signaling, Cat# 5483S), anti-FIS1 (Abcam ...
• Regulation of cell–nanoparticle interactions through mechanobiology

  Marco Cassani, et al., bioRxiv - Bioengineering 2024

  Quote: ... rabbit anti-p-MOB1 (Thr35) (8699, Cell Signaling Technology); mouse anti-Glyceraldehyde 3-phosphate dehydrogenase (GAPDH)-peroxidase (69295 ...