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901 - 950 of 10000+ citations for 1 2 4 4 4 Pentachloropentafluorobutane since 2020

• Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)

  Honglin Jiang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Phospho-Erk1/2 (Thr202/Tyr204) (Cell Signaling Technology, 4370, Dilution: 1:1000); Erk1/2 (Cell Signaling Technology ...
• Intermittent ERK oscillations downstream of FGF in mouse embryonic stem cells

  Dhruv Raina, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Primary antibodies used were anti-pERK1/2 1:200 (4370S, Cell Signaling), anti-E-Cad 1:200 (M108 ...
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... anti-phospho-p44/42 MAPK (pErk1/2) (Cell signaling, 9101, 1:1000), anti-Collagen type III (Abcam ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/100 Phospho-Myosin Light Chain 2 (Ser19) (Cell Signaling Technologies, 3675); 1/250 p62/SQSTM (Cell Signaling Technologies ...
• Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

  Timothy N. Hoang, et al., bioRxiv - Immunology 2020

  Quote: ... pSTAT3 (Cell Signaling; Cat. No. 9145L at 1:200 for 2 hours), Iba-1 (BioCare ...
• A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary

  Wen Lu, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit phospho-MLC (pMLC 2/Ser19, 1:100, Cell Signaling, Cat# 3671); mouse monoclonal anti-DHC antibody (2C11-2 ...
• Negative durotaxis: cell movement toward softer environments

  Aleksi Isomursu, et al., bioRxiv - Biophysics 2020

  Quote: ... rbt anti-ERK1/2 (Cell Signaling Technology, 9102, 1:1000 for WB), rbt anti-p-ERK1/2 (T202/Y204 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... and anti-tERK1/2 (1:5000; Cell Signaling Technology, Cat. no. 9102). CXCR7pp2 was synthesized at the Tufts University Core Facility.
• Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype

  Jordi Creus-Muncunill, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-p44/42 MAPK (Erk1/2) Antibody (1:1000, #9102, Cell Signaling), anti-C1q [4.8] (1:500 ...
• Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

  Jason J. Northey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p44/42 MAPK (ERK1/2) (Cell Signaling Technology, Cat. #: 9102, 1:1000), phospho-PR (S294 ...
• Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance

  Xiaopeng Tang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-total-IκBα (1:2□000 dilution, 4814T, Cell Signaling Technology, USA), anti-phospho-NF-κB p65 (1:1□000 dilution ...
• Biased agonists of the chemokine receptor CXCR3 differentially drive formation of G_αi:β-arrestin complexes

  Kevin Zheng, et al., bioRxiv - Biochemistry 2020

  Quote: ... phosphorylated extracellular regulated kinase 1/2 (ERK) (Cell Signaling Technology, Danvers, MA) and total ERK (Millipore ...
• Jak2^V617F Reversible Activation Shows an Essential Requirement for Jak2^V617F in Myeloproliferative Neoplasms

  Andrew Dunbar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and phospho-44/42 MAPK (Erk1/2) (Cell Signaling 4376, 1:100). Pictures were taken at 100X ...
• ATP allosterically stabilizes Integrin-linked kinase for efficient force generation

  Isabel M. Martin, et al., bioRxiv - Biophysics 2021

  Quote: ... phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling; 3674; 1:200), Paxillin (BD Transduction Laboratories ...
• Oxidative Stress and Neuroinflammation in a Rat Model of Co-Morbid Obesity and Psychogenic Stress

  Jose M. Santiago Santana, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-rabbit SOD-2 (1:2000; catalog #13141S; Cell Signaling, Danvers, MA); anti-rabbit GFAP (1:5000 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-phospho-Erk1/2 (1:250 dilution; Cat. #: 4370, Cell Signaling); γH2AX (1:100 dilution ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (T202/Y204) (Cell Signaling 4370, 1:2000), rabbit anti-ERK1/2 (Cell Signaling 4695 ...
• TOP-2 is differentially required for the proper maintenance of cohesin on meiotic chromosomes in C. elegans spermatogenesis and oogenesis

  Christine Rourke, Aimee Jaramillo-Lambert, bioRxiv - Genetics 2021

  Quote: ... rabbit anti-AIR-2 [(1:500) Figure 2B] (Cell Signaling Technology, 2914S), Histone H3 phospho-T3 (1:750 ...
• Single Serine on TSC2 Exerts Biased Control over mTORC1 Activation by ERK1/2 but Not Akt

  Brittany L. Dunkerly-Eyring, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 1:1000). Total protein stain used was Revert Total Protein Stain (Licor) ...
• Metformin-mediated mitochondrial protection post-cardiac arrest improves EEG activity and confers neuroprotection and survival benefit

  Muhammad Shoaib, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Total AMPK β1/2 (1:1000; Cell Signaling Technology, Beverly, MA). Detection used anti-rabbit horseradish peroxidase–conjugated secondary antibody (1:2000 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p-p44/42 MAPK (pERK1/2) (Cell Signaling Technology, 9101S, 1:1,000) and β-actin (Cell Signaling Technology ...
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

  Nanami Morooka, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (1:500, Cell signaling), and mouse anti-RFP (1:500 ...
• An atlas of epithelial cell states and plasticity in lung adenocarcinoma

  Guangchun Han, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p44/42 MAPK (ERK1/2, rabbit, Cell Signaling Technology, 9102, 1:2000), or S6 (E.573.4 ...
• Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

  Giusy Pizzirusso, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000 anti-Synaptotagmin-2 polyclonal rabbit antibody (#60889, Cell Signaling Technology), 1:1000 anti-GABA-A Receptor beta 3 polyclonal rabbit antibody (#NB300-199 ...
• Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction

  Yan Xiong, et al., bioRxiv - Physiology 2023

  Quote: ... Erk1/2 antibody (rabbit, 1:2000; all from Cell Signaling Technology, USA), and α-tubulin antibody (mouse,1:1000 ...
• Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana

  Márcia Gonçalves Dias, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1:2,000 rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling 9102S); 1:10,000 goat anti-rabbit-IgG (Sigma A0545) ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000; 9101; Cell Signaling Technology, Inc.); ERK1/2 (1:1000 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000, Cell Signaling Technology, Cat# 9106), ERK1/2 (1:1000 ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (#4370, Cell Signaling Technology, 1:1000), ERK (#9102S ...
• Retinoid acid receptor β mechanically regulates the activity of pancreatic cancer cells

  Carlos Matellan, et al., bioRxiv - Bioengineering 2022

  Quote: ... or anti-MLC-2 antibodies (Cell Signaling Technology, 3672S, Rabbit, 1:100) and anti-PAN cytokeratin (Abcam ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Phospho-p44/42 (ERK1/2) (1:1000, 197G2, 4377T, Cell Signaling), anti-p44/42 (ERK1/2 ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit monoclonal anti-p-ERK1/2 (Cell Signaling Technology 4370S, 1:100), rabbit polyclonal anti-p53 (Invitrogen PA5-88098 ...
• A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

  Lisonia Gkioni, et al., bioRxiv - Physiology 2024

  Quote: ... and total ERK1/2 (1:1000, anti-rabbit, Cell Signaling Technology, 4695) in 5% fatty-acid free BSA in TBS-T at 4°C overnight ...
• Rigosertib Reverses Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome

  Levi Legler, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-phospho-ERK 1/2 (Thr202/Tyr204) (#9101) (Cell Signaling Technology). Visualization of the primary antibody binding was performed using the Li-Cor anti-rabbit 680 IRDye system in conjunction with the Li-Cor Odyssey FC ...
• Gestational arsenite exposure alters maternal postpartum heart size and induces Ca²⁺ handling dysregulation in cardiomyocytes

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Rabbit mAb, Cell Signaling, 9102S), p-p44/42 MAPK (T202/Y204 ...
• Rhes, a Striatal Enriched Protein, Regulates Post-Translational Small-Ubiquitin-like-Modifier (SUMO) Modification of Nuclear Proteins and Alters Gene Expression

  Oscar Rivera, et al., bioRxiv - Biochemistry 2020

  Quote: ... #2983), Histone H3 (1:10,000, #4499), MEK1/2 (1:1000, #8727) and LDH (1:5000, #2012;) were from Cell Signaling Technology, Inc ...
• Role of miR-181c in Diet-Induced Obesity Through Regulation of Lipid Synthesis in Liver

  Kei Akiyoshi, et al., bioRxiv - Cell Biology 2021

  Quote: ... the membrane was incubated with antibody that recognizes proteins IDH 1 (1:1000) and IDH 2 (1:1000) (Cell Signaling, MA) and α-Tubulin (Abcam ...
• TRIM46 is not required for axon specification or axon initial segment formation in vivo

  Allison J. Melton, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000) and TRIM46 (#1 in text: Abcam Cat# ab307967, RRID:AB_3096363, 1:200-1:1000, #2 in text: Cell Signaling Technology Cat# 92574, RRID:AB_3096364, 1:200), rabbit polyclonal antibodies against βIV-spectrin (M.N ...
• Iodoacetic acid disrupts mouse oocyte maturation by inducing oxidative stress and spindle abnormalities

  Xiaofei Jiao, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-phospho-p44/42 MAPK (Erk1/2) (1:200, Cell Signaling Technologies). As for γ-H2AX or phospho-p44/42 MAPK (Erk1/2 ...
• MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

  Carolyn Sangokoya, Robert Blelloch, bioRxiv - Developmental Biology 2020

  Quote: ... and p44/42 Erk1/2 at 1:1000 dilution (Cell Signaling Technology, 4696). Secondary infrared-dye antibodies were used at 1:10,000 ...
• MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

  Carolyn Sangokoya, Robert Blelloch, bioRxiv - Developmental Biology 2020

  Quote: ... and p44/42 Erk1/2 at 1:700 dilution (Cell Signaling Technology, 4696) for 30 minutes at 4°C followed by incubation with species-specific secondary antibodies Alexa Fluor 568 or 594 goat anti-mouse IgG at 1:200 dilution (Invitrogen ...
• Metabolic Derangement in Polycystic Kidney Disease Mouse Models Is Ameliorated by Mitochondrial-Targeted Antioxidants

  Nastaran Daneshgar, et al., bioRxiv - Pathology 2021

  Quote: ... and phospho-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 4370, 1:500), anti-Catalase (R&D ...
• The Chlamydia protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

  Karsten Meier, et al., bioRxiv - Microbiology 2022

  Quote: ... rabbit-anti-Rab35 (1:1000; Cell Signaling, 9690; or Proteintech, 11329-2-AP), mouse-anti-β-actin (1:2000 ...
• Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome

  Fikri Birey, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Phospho-Myosin Light Chain 2 (Ser19) (rabbit, Cell Signaling, 1:1,000, 3671S) antibodies for 72 h at 4 °C ...
• Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development

  Nilay Kumar, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Phospho-Myosin Light Chain 2 (Ser19) (1:50, Rabbit, Cell Signaling Technology #3671S), α-Rho1 (1:10 ...
• Nuclear SUN1 Stabilizes Endothelial Cell Junctions via Microtubules to Regulate Blood Vessel Formation

  Danielle B Buglak, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho-myosin light chain 2 (Thr18/Ser19) (1:500, 3674S, Cell Signaling), anti-alpha-tubulin (1:500 ...
• Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia

  L. Martin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phosphorylated Erk1-2 (Thr180/Tyr182) (Cell Signaling Technology, #4370; 1:100 dilution), anti-phosphorylated P38 (Abcam ...
• Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane

  Idil Ulengin-Talkish, et al., bioRxiv - Biochemistry 2021

  Quote: ... ERK using p44/42 Erk1/2 antibody (1:3,000; 3A7, Cell Signaling Technologies). Phosphorylation status of FAM126A in each treatment was quantified as pFAM126A S485 signal/FLAG signal and reported relative to that of in DMSO treated FAM126A WT sample ...
• Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways

  F Quessy, et al., bioRxiv - Neuroscience 2021

  Quote: ... Phospho-p44/42 MAPK 1:250 (Erk1/2) (Thr202/Tyr204) (Cell Signaling, 9101), DAT 1:500 (Millipore ...
• Neuron-like function of the nephron central command

  Georgina Gyarmati, et al., bioRxiv - Physiology 2021

  Quote: ... anti-cyclooxygenase 2 (COX2) antibody (1:100, 12282S, Cell Signaling Technology, Danvers, MA,), anti-Na-K-2Cl cotransporter antibody (NKCC2 1:100 ...