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851 - 900 of 10000+ citations for 1 2 4 4 4 Pentachloropentafluorobutane since 2020

• Loss of presenilin-1 in smooth muscle cells ameliorates elastin aortopathy

  Junichi Saito, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-PSEN-2 (Cell Signaling Technology, 9979; 1:250), rabbit anti-HES1 (Cell Signaling Technology ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) (#4695, Cell signaling, 1:1000), ROCK2 (#8236 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-phospho-MEK1/2 (1:1000; #9121; Cell Signaling), goat anti-FLAP (1:1000 ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cycle 2 F4/80 (Cell Signaling, 70076S, 1:500, 1hr), Cycle 3 CD45 (BD Pharmingen ...
• Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma

  Todd A. Young, et al., bioRxiv - Cancer Biology 2024

  Quote: ... GLUD1/2 (1:1000, Cell Signaling Technology Cat# 12793, RRID:AB_2750880); GPX4 (1:1000 ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-p-ERK1/2 (1:500, Cell Signaling 9101S), rabbit anti-RFP (1:500 ...
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... p44/42 MAPK Erk1/2 (Cell Signaling 4695, 1:1000), RNApol2 PS2 (Abcam ab5095 ...
• Targeting the Src pathway enhances the efficacy of selective FGFR inhibitors in cancers with FGFR3 alterations

  Nadia Carvalho Lima, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-Erk1/2 T202/Y404 (4370) 1:2000 and Erk1/1 (4695) 1:2000-1:5000 (all from Cell Signaling); and Tubulin (T5168 ...
• Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis

  Astrid Cleven, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit mAb P44/42 MAPK (Erk 1/2) (137F5) (1:1,000; #4695; Cell Signaling Technology), rabbit mAb Phospho-MAPK (Erk 1/2 Thr202/Tyr204 ...
• Ubiquitin specific protease 1 expression and function in T cell immunity

  Kyla D Omilusik, et al., bioRxiv - Immunology 2021

  Quote: ... Id2 (1:1000; 9-2-8, CalBioeagents or D39E8, Cell Signaling), Id3 (1:1000 ...
• Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy

  Yeon-Ju Lee, et al., bioRxiv - Biochemistry 2022

  Quote: ... Bcl-2-associated X protein (BAX) (1:1000, Cell Signaling Technology), cytochrome c (1:500 ...
• Metabolic Derangement in Polycystic Kidney Disease Mouse Models Is Ameliorated by Mitochondrial-Targeted Antioxidants

  Nastaran Daneshgar, et al., bioRxiv - Pathology 2021

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling Technology, 4695, 1:500) and phospho-p44/42 MAPK (ERK1/2 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... phospho-Erk1/2 (1:1000; Thr202/Thr204; 9101; Cell Signaling Technology); Erk1/2 (1:1000 ...
• Computational pharmacogenomics screen identifies synergistic statin-compound combinations as anti-breast cancer therapies

  Jenna van Leeuwen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Cell Signaling Technology, 4695), PARP (1:1000 ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4370S), anti-ERK1/2 antibody (1:1000 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-pERK1/2 (1:5000; Cell Signaling Technology, Cat. no. 9101), and anti-tERK1/2 (1:5000 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and anti-pLATS1/2 (1:200, Cell Signaling Technology, #8654, RRID:AB_10971635). Subsequently ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-PKM1/2 mAb (clone C103A3, 1:1000, Cell Signaling 3582), anti-TOM20 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-ERK1/2 (1:1000, Cat#: 4377, Cell Signaling, Danvers, MA), total ERK1/2 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total ERK1/2 (1:1000, Cat#: 9102, Cell Signaling, Danvers, MA), phospho-JNK (1:1000 ...
• Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome

  Fikri Birey, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Myosin Light Chain 2 (rabbit, 1:1,000, Cell Signaling, 8505S), and Phospho-Myosin Light Chain 2 (Ser19 ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling, 9102S, 1:500), anti-phospho p44/42 MAPK (Erk1/2 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 2 μl of anti-MCL-1 antibody (Cell signaling mAb #94296) and 10μl of beads were then used for 200 μg of proteins following manufacturer’s instructions (direct protocol) ...
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell signaling, 4695, 1:1000), anti-phospho-p44/42 MAPK (pErk1/2 ...
• NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

  Claudia Cirotti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK 1/2 (Thr202/Tyr204) (D13.14.4E) (Cell Signaling Technology), anti-Ubiquitin (P4D1 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 4695S, 1:1,000), p-p44/42 MAPK (pERK1/2 ...
• Anti-apoptotic and anti-inflammatory properties of grapefruit IntegroPectin on human microglial HMC3 cell line

  Miriana Scordino, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-p-ERK1/2 (1:1000, 9101 Cell Signaling Technology), rabbit anti-p-Akt (1:1000 ...
• Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

  Adrian J. Luna, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Immunohistochemical detection of p-ERK1/2 (Cell Signaling #4370; 1:500) required the tyramide signal amplification (TSA ...
• Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

  Jayne Aiken, Erika L. F. Holzbaur, bioRxiv - Cell Biology 2023

  Quote: ... and Synaptobrevin-2 (anti-rabbit; Cell Signaling; 13508; 1:250 dilution). Following three washes with PBS ...
• P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway

  Zhijia Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling Technology, 1:4000). Manufacturers provide validation for all antibodies.
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-phospho myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-cofilin (Abcam ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-phospho myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-cofilin (Abcam ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-phospho myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-phospho myosin light chain 2 (Cell signaling ...
• CRIPTO promotes extracellular vesicle uptake and activation of cancer associated fibroblasts

  David W. Freeman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-ERK1/2 (Thr202/204) (Clone D13.144E, Cell Signaling, 1:1000), ERK1/2 (L34F12 ...
• Prenatal Arsenite Exposure Alters Maternal Cardiac Remodeling During Late Pregnancy

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Rabbit mAb, Cell Signaling), and p-p44/42 MAPK (T202/Y204 ...
• Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor

  Jie Li, Jiayi Wu, Xiao-chen Bai, Eunhee Choi, bioRxiv - Cell Biology 2022

  Quote: ... anti-pERK1/2 (WB, 1:000; 197G2, Cat. #4377, Cell Signaling); anti-IR (WB ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... Erk1/2 (p44/42 MAPK) (1:1000, #4695; Cell Signaling Technology), p-Akt (1:2000 ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Cell Signaling 4376S, 1:1000) and Vinculin (Abcam ab129002 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phospho-MAPKAPK-2 (Thr222) (1:1000, Cell Signaling 3316), rabbit anti-p38 MAPK (1:1000 ...
• Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation

  Qin Ni, et al., bioRxiv - Biophysics 2024

  Quote: ... anti-p44/42 MAPK (ERK1/2; Cell Signaling; 4695; 1:1000). GAPDH was used as a loading control (Cell Signaling ...
• PEPITEM Tripeptides and Peptidomimetics: Next-Generation Modulators of Inflammation in Immune-Mediated Conditions

  Anella Saviano, et al., bioRxiv - Immunology 2024

  Quote: ... rabbit monoclonal COX-2 (1:1000; D5H5; both from Cell Signaling) and mouse monoclonal anti-beta-actin (0.01 µg mL−1 ...
• FDA-Approved MEK1/2 Inhibitor, Trametinib, Protects Mice from Cisplatin and Noise-Induced Hearing Loss

  Richard D. Lutze, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-pERK1/2 (Thr202/Tyr204, 9101S, Cell Signaling Technologies, 1:1000) and anti-GAPDH (ab181602 ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... P-ERK1/2 (Thr202/Tyr204) (1:1000, #9101, Cell Signaling Technology), β-actin (1:1000 ...
• Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice

  Emily R Roberts, et al., bioRxiv - Physiology 2024

  Quote: ... anti-RAC1/2/3 (Cell Signaling Technology, Cat# 2465P, 1:1000), anti-RHOA (Cell Signaling Technology ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... phospho-MEK1/2 (S217/S221) (1:1000, Cell Signaling Technology #9121), total MEK1/2 (1:1000 ...
• Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial maturity

  E O’Loughlin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... phospho-SHP-2 (1:1000 for immunoblot; Cell Signaling Technology #3751), phospho-MEK (1:1000 for immunoblot ...
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... p44/42 MAPK phospho-Erk1/2 (Cell Signaling 4376, 1:2000), p44/42 MAPK Erk1/2 (Cell Signaling 4695 ...
• Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

  Mary C. Rominger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p44/42 MAPK 1:1000 (Erk1/2) (Cell Signaling Technology, 9107), Phospho-p44/42 MAPK (Erk1/2 ...
• Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis

  Astrid Cleven, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit mAb Phospho-MAPK (Erk 1/2 Thr202/Tyr204) (D13.14.4E) (1:1,000; #4370; Cell Signaling Technology, mouse mAb GAPDH (1;5000 ...
• Methods for detection of cardiac glycogen-autophagy

  Parisa Koutsifeli, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Antibodies were sourced for GABARAPL1 (#1: Proteintech, #11010-1-AP; #2 Abcam, #ab86497; #3: Cell Signaling, #26632), LC3B (Cell Signaling #2775) ...