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8501 - 8550 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

  Vanessa Goyon, et al., bioRxiv - Cell Biology 2022

  Quote: ... CYP3A11 by rabbit polyclonal antibodies (13384, 1:500, Cell Signaling), CYP4A14 by goat polyclonal antibodies (sc-46087 ...
• SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

  Vanessa Goyon, et al., bioRxiv - Cell Biology 2022

  Quote: ... CHOP by rabbit polyclonal antibodies (5554, 1:500, Cell Signaling), BiP by rabbit polyclonal antibodies (ADI-SPA-826-D ...
• SUMOylation of ABCD3 restricts bile acid synthesis and regulates metabolic homeostasis

  Vanessa Goyon, et al., bioRxiv - Cell Biology 2022

  Quote: ... eIF2α by mouse monoclonal antibodies (2103, 1:500, Cell Signaling), phospho-eIF2α by rabbit polyclonal antibodies (SAB4504388 ...
• Conserved Pib2 regions have distinct roles in TORC1 regulation at the vacuole

  Kayla K. Troutman, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho-Rps6 (1:1000, 4858, Cell Signaling Technology, Danvers). Secondary antibodies were incubated for 1 hour at room temperature and were as follows ...
• Focal adhesion-based cell migration is differentially regulated in vivo versus in vitro by Paxillin phosphorylation

  Qian Xue, et al., bioRxiv - Cell Biology 2022

  Quote: ... Rabbit anti-pY118-Paxillin (Cell Signaling Technology, 9369, 1:1000), Rabbit anti-FAK (Cell Signaling Technology ...
• Substrate trapping approach identifies TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

  Emily Yang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:100 anti-RIG-I (Cell Signaling Technology, Danvers, MA), 1:1000 anti-HA (Roche Life Sciences) ...
• Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling

  Olivia Harding, Erika L.F. Holzbaur, bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho-OPTN (Ser177) (Cell Signaling Technology, 57548, 1:200), anti-GABARAP+GABARAPL1+GABARAPL2 (abcam ...
• Calcineurin associates with centrosomes and regulates cilia length maintenance

  Eirini Tsekitsidou, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-myc 71D10 (1:300, Cell Signaling Technology, 2278S), rabbit anti-POC5 CE037 (1:100 ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-GAPDH mAB (clone 14C10, 1:2000, Cell Signaling 2118), anti-GDH mAB (clone D9F7P ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-G6PD mAB (clone D5D2, 1:1000, Cell Signaling 12263), anti-GAPDH mAB (clone 14C10 ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-HK1 mAB (clone C35C4, 1:1000; Cell Signaling 2024), anti-HK2 mAB (clone C64G5 ...
• Energy Expenditure during Cell Spreading Regulates the Stem Cells Responses to Matrix Stiffness

  Jing Xie, et al., bioRxiv - Cell Biology 2021

  Quote: Cells were lysed with RIPA buffer (1:10, Cell Signaling) supplemented with protease and phosphatase inhibitors (Roche) ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-active β-Catenin (Cell signaling technology; #8814, 1:1,000), anti-β-Catenin (BD Biosciences ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phospho ERK1/2 (Cell Signaling technology; #4376, 1:1,000), anti-ERK1/2 (Cell Signaling technology ...
• Ciliopathic micrognathia is caused by aberrant skeletal differentiation and remodeling

  Christian Louis Bonatto Paese, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and Sox9-Conjugate AlexaFluor-488 (1:100 - Cell Signaling – 94794). Nuclei counterstaining was carried out by incubation in 1 μg/ml DAPI in PBS + Triton 1% for 2 hours and processed for clearing with Ce3D solution overnight (Li et al. ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-E-cadherin rabbit monoclonal (1:200) (Cell Signaling Technologies), anti-MUC5B rabbit monoclonal (1:500 ...
• Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born neurons in the mouse olfactory bulb

  Kaizhen Li, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit monoclonal antibody against pCREB (Cell Signaling 9198S, 1:400), mouse monoclonal antibody against NeuN (Millipore MAB377 ...
• Gain-of-function assay for SARS-CoV-2 M^pro inhibition in living cells

  Seyad Arad Moghadasi, et al., bioRxiv - Microbiology 2020

  Quote: ... and rabbit anti-β-actin (1:10,000 Cell Signaling #4967) followed by goat/sheep anti-mouse IgG IRDye 680 (1:10,000 LI-COR #926-68070 ...
• Growth of tumor emboli within a vessel model reveals dependence on the magnitude of mechanical constraint

  Jonathan Kulwatno, et al., bioRxiv - Cell Biology 2020

  Quote: Primary antibodies for myosin IIa (1:5000; Cell Signaling Technology) and GAPDH (1:15000 ...
• RAN translation of the expanded CAG repeats in the SCA3 disease context

  Magdalena Jazurek-Ciesiolka, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-c-Myc (1:1000, Cell Signaling Technology, CST), rabbit anti-His (1:1000 ...
• Control of ribosomal protein synthesis by Microprocessor complex

  Xuan Jiang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-Lamin A/C (1:2500, Cell signaling Technology, 2032), anti-Gata1 (1:200 ...
• Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Male and Female Mice

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... phosphor-Src (Tyr416) (1:1000, Cell Signaling Technology, cat. # 6943), CDK5 (1:1000 ...
• Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Male and Female Mice

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... phospho-GSK3β (Ser9) (1:1000, Cell Signaling Technology, cat. #9322), PP2Ac (1:1000 ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-rabbit IgG (1:1000, Cell Signaling Technology, #7074), chicken polyclonal anti-UCHL1 (1:2000 ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit polyclonal anti-p38 (1:1000, Cell Signaling Technology, #9212), rabbit monoclonal anti-phospho-p38 (Thr180/Tyr182 ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit polyclonal anti-p38 (1:1000, Cell Signaling Technology, #9212) or rabbit monoclonal anti-phospho-p38 (Thr180/Tyr182 ...
• ARID1A loss derepresses human endogenous retrovirus-H to modulate BRD4-dependent transcription

  Chunhong Yu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse anti-α-Tubulin Ab (1:3000, Cell Signaling, 3873s). Primary antibodies used in this study were listed in Supplementary Table 11.
• Telomeric Double Strand Breaks Facilitate Formation of 5’ C-Rich Overhangs in G1 Human Cells

  Christopher B Nelson, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Rabbit Anti-phospho Thr68 CHK2 (Cell signaling 2661, 1:1000), Rabbit Anti-EXO1 (Proteintech 16352-1-AP ...
• Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neurons

  Ryan Insolera, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti Atg8 (GABARAP)* at 1:500 (Cell Signaling Technology #13733S), anti GFP at 1:1000 (Aves Labs #GFP1020) ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total JNK (1:1000, Cat#: 9252, Cell Signaling, Danvers, MA), phospho-p38 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total S6K1 (1:1000, Cat#: 9202, Cell Signaling, Danvers, MA), phospho-AKT (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total p65 (1:1000, Cat#: 8242, Cell Signaling, Danvers, MA), phospho-ERK1/2 (1:1000 ...
• Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

  Hideaki Fujiwara, et al., bioRxiv - Immunology 2020

  Quote: ... Tom20 (#42406, D8T4N, 1:1000, Cell Signaling Technology, Danvers, MA) and anti-β actin (#8226 ...
• TGF-β-driven downregulation of the Wnt/β-Catenin transcription factor TCF7L2/TCF4 in PDGFRα⁺ fibroblasts

  Osvaldo Contreras, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-c-Jun (60A8) (1:1000; 9165, Cell Signaling), rabbit anti-β-Catenin (1:2000 ...
• TGF-β-driven downregulation of the Wnt/β-Catenin transcription factor TCF7L2/TCF4 in PDGFRα⁺ fibroblasts

  Osvaldo Contreras, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-TCF4/TCF7L2 (C48H11) (1:1000; 2569, Cell Signaling), rabbit anti-c-Jun (60A8 ...
• TCF7L2 regulates postmitotic differentiation programs and excitability patterns in the thalamus

  Marcin Andrzej Lipiec, et al., bioRxiv - Neuroscience 2020

  Quote: ... Antibodies against TCF7L2 (1:500; Cat. no. 2569, Cell Signaling), Cav3.1 (1:500 ...
• Lack of p62 impairs glycogen aggregation and exacerbates pathology in a mouse model of myoclonic epilepsy of Lafora

  Pasquale Pellegrini, et al., bioRxiv - Neuroscience 2021

  Quote: ... Primary antibodies anti-MGS (15B1) (1:250, 3886 Cell Signaling), anti-GFAP (1:250 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... Myelin Basic Protein (MBP; 1:300; Cell Signaling Technology, CST), NeuN (1:300 ...
• Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons

  Chunchu Deng, et al., bioRxiv - Neuroscience 2021

  Quote: ... polyclonal rabbit anti-eEF2 (23325, Cell Signaling Technology; 1:50), monoclonal mouse anti-S6 ribosomal protein (MA515123 ...
• A genetic compensatory mechanism regulated by c-Jun and Mef2d modulates the expression of distinct class IIa HDACs to ensure peripheral nerve myelination and repair

  Sergio Velasco-Aviles, et al., bioRxiv - Cell Biology 2021

  Quote: Immunofluorescence antibodies: c-Jun (Cell Signaling Technology, rabbit 1:800), Ki67 (Abcam ...
• Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition

  Rajika Arora, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit polyclonal anti-Argonaute2 (1:2000 C34C6 Cell Signaling Technologies), rabbit anti-Drosha (1:2000 ...
• The influenza A virus host shutoff factor PA-X is rapidly turned over in a strain-specific manner

  Rachel Emily Levene, et al., bioRxiv - Microbiology 2020

  Quote: ... and human β-tubulin (1:1000, Cell Signaling Technologies 2128). Secondary antibodies conjugated to HRP were purchased from Southern Biotechnologies (rabbit ...
• Human Cytomegalovirus uses a Host Stress Response to Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very Long Chain Fatty Acids

  Yuecheng Xi, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit monoclonal anti-PERK (Cell Signaling; #3192; 1:600 dilution), monoclonal anti-ATF4 D4B8 (Cell Signaling ...
• Pharmacological tuning of microRNAs in FAP-derived Extracellular Vesicles by HDAC inhibitors promotes regeneration and reduces fibrosis in dystrophic muscles

  M. Sandonà, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Alix (3A9) (1/500, Cell Signaling Technologies #2171), mouse monoclonal Col3a1 (B-10 ...
• SUFFICIENT ACTIVITY OF THE UBIQUITIN PROTEASOME SYSTEM IN AGED MICE AND DURING RETINAL DEGENERATION SUPPORTS DHFR-BASED CONDITIONAL CONTROL OF PROTEIN ABUNDANCE IN THE RETINA

  Hui Peng, et al., bioRxiv - Physiology 2021

  Quote: ... mouse anti-p53 (1:1000; Cell Signaling Technology, cat# 2524S), mouse anti-ubiquitin (1:1000 ...
• Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function

  Diana Fernández-Suárez, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti phospho-Ser845 GluA1 (1:500, 8084, Cell Signaling); mouse anti tubulin alpha (1:10000 ...
• Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function

  Diana Fernández-Suárez, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti phospho-Ser831 GluA1 (1:500, 75574, Cell Signaling); rabbit anti phospho-Ser845 GluA1 (1:500 ...
• A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

  Han-Soo Kim, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... ERK 1/2 from Cell Signaling Technology (Danver, MA, USA). All antibodies were diluted to 1:1000 v/v in 5% BSA in DPBS (Welgene).
• JAG1 intracellular domain acts as a transcriptional cofactor that forms an oncogenic transcriptional complex with DDX17/SMAD3/TGIF2

  Eun-Jung Kim, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-cleaved Notch1 (1:1000, Cat. #2421L; Cell Signaling Technology), anti-SOX2 (1:1000 ...
• SOX11 is a lineage-dependency factor and master epigenetic regulator in neuroblastoma

  Bieke Decaesteker, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-c-MYB antibody (12319S, Cell Signaling, 1:1000 dilution), anti-MYCN antibody (SC-53993 ...