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8401 - 8450 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel

  Jianlong Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-pHH3 (1:200, Cell Signaling Technology, #9701); muscarinic M3 receptor (CHRM3 ...
• ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid cells

  Akira Mabuchi, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-GM130 (Cell Signaling Technology, #12480; IF 1:1,000), anti-HNRNPA1 (Santa Cruz Biotechnology ...
• Lymphatic-Preserving Treatment Sequencing with Immune Checkpoint Inhibition Unleashes cDC1-Dependent Antitumor Immunity in HNSCC

  Robert Saddawi-Konefka, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Rabbit anti-CD11c (D1V9Y, Cell Signaling Technology, 1:250) was diluted in Renaissance antibody diluent (Biocare Medical) ...
• Integrated analysis reveals FOXA1 and Ku70/Ku80 as direct targets of ivermectin in prostate cancer

  Shidong Lv, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and PSA (Cell Signaling Technology Cat# 2475, 1:1000) through the immunoperoxidase technique.
• Single-Cell Transcriptomic Analyses of Tumor Ecosystems and Spatial Architectures in Human Small Cell Lung Cancer

  Huiling Ouyang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-YAP1 (1:100, Rabbit polyclonal, Cell Signaling Technology), and anti-POU2F3 (1:250 ...
• The conserved zinc-finger protein GTSF1 helps PIWI proteins achieve their full catalytic potential

  Amena Arif, et al., bioRxiv - Biochemistry 2022

  Quote: ... and rabbit anti-Tubulin (Cell Signaling, 2144; 1:1000) for 2 hours at room temperature ...
• CRISPR base editing of cis-regulatory elements enables target gene perturbations

  Colin K.W. Lim, et al., bioRxiv - Bioengineering 2022

  Quote: ... rabbit anti-HA (1:500; Cell Signaling Technology, 3724S), rabbit anti-NeuN (1:500 ...
• The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor

  Ritvija Agrawal, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-myc (1:500, Cell Signaling Technologies #9811), and rabbit anti-FLAG (1:166 ...
• PCDH7 Promotes Cell Migration by Regulating Myosin Activity

  Mohammad Haroon Qureshi, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-pERM rabbit (Cell Signaling Technology 3726s, 1:500), phalloidin iFlour555 (ab176756 ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p-Akt(ser473) (1/500, Cell Signaling Technologies, #4060T) HSPB1 (1/1000 ...
• NFYA promotes the malignant behavior of triple-negative breast cancer through the regulation of lipid metabolism

  Nobuhiro Okada, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 1 µM Oligomycin A (Cell Signaling Technology, no. 9996) was injected to inhibit ATPase V ...
• Genomic screening reveals UBA1 as a potent and druggable target in c-MYC-high TNBC models

  Sheeba Jacob, et al., bioRxiv - Cancer Biology 2022

  Quote: IHC staining for CC3 (1:500, Cell Signaling #9664) was performed in the VCU Tissue and Data Acquisition and Analysis Core with the Leica Bond RX autostainer using heat-induced epitope retrieval buffer 2 (Leica ...
• Cell fusion upregulates PD-L1 expression and promotes tumor formation

  Youichi Tajima, Futoshi Shibasaki, Hisao Masai, bioRxiv - Cancer Biology 2022

  Quote: ... anti-PD-1 (mouse specific)(#84651, Cell Signaling Technology), anti-PD-L1 (Extracellular domain specific ...
• Clearance of defective muscle stem cells by senolytics reduces the expression of senescence-associated secretory phenotype and restores myogenesis in myotonic dystrophy type 1

  Talita C. Conte, et al., bioRxiv - Cell Biology 2022

  Quote: ... and anti-beta-actin (4967S, 1:5,000; Cell Signaling) as primary antibodies ...
• eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways

  Ibrahim Ahmed, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-ERK (Cell Signaling Technologies, 4695S, 1:1,000). Secondary antibodies used ...
• A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia

  Olga Lancho, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p-4EB-P1 (1:1000, 2855S, Cell Signaling), anti-p53 (1:1000 ...
• Prediction of Resistant Mutations against Upcoming ALK-TKIs, Repotrectinib (TPX-0005) and Ensartinib (X-396)

  Yuta Doi, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HRP-linked antibody (Cell Signaling Technologies, #7074, 1:2000) and anti-mouse IgG ...
• Prediction of Resistant Mutations against Upcoming ALK-TKIs, Repotrectinib (TPX-0005) and Ensartinib (X-396)

  Yuta Doi, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HRP-linked antibody (Cell Signaling Technologies, #7076, 1:2000). Then the membranes were washed with TBST and incubated with Immobilon® Western Chemiluminescent HRP Substrate (EMD Millipore Corporation ...
• Focal adhesion-based cell migration is differentially regulated in vivo versus in vitro by Paxillin phosphorylation

  Qian Xue, et al., bioRxiv - Cell Biology 2022

  Quote: ... Rabbit anti-pFAK397 (Cell Signaling Technology, 3283, 1:1000), Chicken anti-GFP (Abcam ...
• Focal adhesion-based cell migration is differentially regulated in vivo versus in vitro by Paxillin phosphorylation

  Qian Xue, et al., bioRxiv - Cell Biology 2022

  Quote: ... Rabbit anti-FAK (Cell Signaling Technology, 3285, 1:1000), Rabbit anti-pFAK397 (Cell Signaling Technology ...
• On optimal temozolomide scheduling for slowly growing gliomas

  Berta Segura-Collar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit anti-pTyr1068-EGFR (1:1.000, Cell Signaling #3777) and rabbit anti-phospho-NF-kB p65 (Ser536 ...
• Profiling DNA break sites and transcriptional changes in response to contextual fear learning

  Ryan T. Stott, Oleg Kritsky, Li-Huei Tsai, bioRxiv - Neuroscience 2021

  Quote: ... GFAP AF647 (1:200; clone GA5; Cell Signaling Technology), and PU.1 PE (1:200 ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-p-PDH (Ser293, 1:1000, Cell Signaling 31866), anti-PKM1/2 mAb (clone C103A3 ...
• Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in LIF heterozygous mice

  Michelle J. Frondelli, et al., bioRxiv - Neuroscience 2020

  Quote: ... & total S6RP (1:1000, Cell Signaling Technology, 2217, RRID:AB_331355) overnight at 4°C ...
• Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen

  Ian Baudi, et al., bioRxiv - Microbiology 2020

  Quote: ... phospho-Stat-1 (#9167) (all from Cell Signaling Technologies), GAPDH (abcam#8245) ...
• FAM72A antagonizes UNG2 to promote mutagenic uracil repair during antibody maturation

  Yuqing Feng, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-His tag antibody (Cell signaling; 1:2000), and anti-UDG antibody (Santa Cruz ...
• Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein

  Mizuki Yamamoto, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-ADAM10 (1:1000, 14194S, Cell Signaling Technology), rabbit anti-Flag-tag (1:1000 ...
• RAB6 GTPase is a crucial regulator of the mammary secretory function controlling STAT5 activation

  Surya Cayre, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-RAB5 (Cell Signaling Technology, CST; #3547S; 1/1000), anti-RAB8 (BD Biosciences ...
• A ubiquitin-based mechanism for the oligogenic inheritance of heterotaxy and heart defects

  Jennifer H. Kong, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-GLI1 (clone L42B10, Cell Signaling, 1:1000); mouse anti-HA.11 (clone 16B12 ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-MUC5AC rabbit monoclonal (1:200) (Cell Signaling Technology), anti-acetyl-alpha-tubulin rabbit monoclonal (1:500 ...
• Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Male and Female Mice

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... p35/p25 (1:1000, Cell Signaling Technology, cat. # 2680), GSK3β (1:1000 ...
• Reduction of Glut1 in retinal neurons but not the RPE alleviates polyol accumulation and normalizes early characteristics of diabetic retinopathy

  Nicholas C. Holoman, et al., bioRxiv - Neuroscience 2020

  Quote: ... and Mo anti-actin (Cell signaling #3700S, 1:1000). PVDF membranes were scanned with an Odyssey infrared scanner and densitometry was performed using LiCor Image Studio Software.
• SerpinB3 drives cancer stem cell survival in glioblastoma

  Adam Lauko, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and c-Myc (Cell Signaling Technology 5605, 1:5000). β-Actin (Bio-Rad 12004163 ...
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 4E-BP1 (1:1000, CST Cell Signaling Tech, 9452S), p-eIF2a (phospho S51 ...
• Dynamin-related Irgm proteins modulate LPS-induced caspase-4 activation and septic shock

  Ryan Finethy, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-LC3 (2775; Cell Signaling Technology; 1:500), goat anti-CD14 (AF982 ...
• TGF-β-driven downregulation of the Wnt/β-Catenin transcription factor TCF7L2/TCF4 in PDGFRα⁺ fibroblasts

  Osvaldo Contreras, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-β-Catenin (1:2000; 9562, Cell Signaling), rabbit anti-histone 3 H3 (1:1000 ...
• Anti-inflammatory role of GM1 and modulatory effects of gangliosides on microglia functions

  Danny Galleguillos, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-p38 MAPK (Cell Signaling 9212; 1:1,000), rabbit anti-phospho-p38 MAPK (Thr180/Tyr182 ...
• Distinct features of brain perivascular fibroblasts and mural cells revealed by in vivo two-photon imaging

  Stephanie K. Bonney, et al., bioRxiv - Neuroscience 2021

  Quote: ... or rabbit anti-Pdgfrα (1:100; Cell signaling; D1E1E) overnight at 4°C ...
• A novel cholinergic neural pathway and its role in the drug relapse

  Teng He, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-NeuN (1:200, Cell Signaling Technology, USA) at 4 °C for 24 h ...
• Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite

  Anna Vilalta, et al., bioRxiv - Biochemistry 2020

  Quote: ... GAPDH (#2118, 1:3000 for western blot; Cell Signaling); Anti-His (C-term)-HRP (#46-0707 ...
• Identification and Characterization of a B-Raf Kinase Alpha Helix Critical for the Activity of MEK Kinase in MAPK Signaling

  Diep Nguyen, et al., bioRxiv - Biochemistry 2020

  Quote: ... or anti-GST antibody (1:1000) (Cell Signaling, #2625). The next day ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-phospho Akt (S473) (Cell Signaling, 4060S, 1:1000), anti-Myosin Light Chain 2/MLC-2V (Proteintech ...
• S-nitrosylated and non-nitrosylated COX2 has differential expression and distinct subcellular localization in normal and breast cancer tissue

  Sonali Jindal, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COX-1 (Cell Signaling Technology # 4841, at 25ng/uL) and GAPDH (14C10 clone ...
• Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth

  Mafalda Santos, et al., bioRxiv - Cell Biology 2021

  Quote: ... incubated with anti-Snail (1:50,Cell Signaling,USA), anti-MMP2 (1:50,Calbiochem,USA ...
• Inhibiting proBDNF to mature BDNF conversion leads to autism-like phenotypes in vivo

  He You, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-SynGAP (1:1000; clone D88G1; Cell Signaling Technology), anti-GluN2B (1:1000 ...
• Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

  Teresa Gagliano, et al., bioRxiv - Cancer Biology 2019

  Quote: ... pAkt-S473 (Cell Signaling Technology, CST, 4060, 1:100), pAkt-Thr308 (Millipore ...
• Both DNA binding domains of p53 are required for its ultra-rapid recruitment to sites of UV damage

  YH. Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... and p53 [clone DO-1] (Cell Signaling Technology #18032); followed by co-staining of secondary antibodies including AlexaFluor488-Goat anti-mouse IgG (A11001 ...
• The hallucinogenic serotonin_2A receptor agonist, DOI, promotes CREB-dependent gene expression of specific plasticity-associated genes in the rodent neocortex

  Lynette A. Desouza, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-CREB (1:1000, Cell Signaling Technology). Blots were washed 3–5 times and incubated with a 1:5000 dilution of horseradish peroxidase-conjugated goat anti-rabbit antibody (GE Healthcare ...
• “A feed-forward Ca²⁺-dependent mechanism boosting glycolysis and OXPHOS by activating Aralar-malate-aspartate shuttle, upon neuronal stimulation”

  Irene Pérez-Liébana, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-p-AMPK T172 (1:1,000, Cell Signaling Technology), anti-β-F1ATPase (1:5,000 ...
• Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signaling

  Abigail U. Carbonell, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rat anti-tubulin 1:1000 (Cell Signaling Tech). Statistical analysis for Western blot was performed in JMP 14 (SAS ...