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8351 - 8400 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer

  Benjamin R. Challoner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and PD-L1 (1:100, E1L3N, Cell Signaling Technology) immunohistochemistry were performed on Leica Bond autostainer ...
• The endoplasmic reticulum membrane protein complex (EMC) negatively regulates intestinal homeostasis through the Hippo signaling pathway

  Lin Shi, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-β-glactosidase (lacZ, 1:1000, Cell Signaling), rabbit anti-PH3 (pSer10 ...
• Vimentin intermediate filaments organize organellar architecture in response to ER stress

  Tom Cremer, et al., bioRxiv - Cell Biology 2022

  Quote: ... and rabbit anti HA (1:1000, Cell signaling #3724) followed by secondary Rabbit anti-mouse-HRP ...
• Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells

  Sameena Wani, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-p-CREB (1:1,000, 9198S; Cell signaling Technology), anti-pPKA (1:1,000 ...
• Programmable RNA Sensing for Cell Monitoring and Manipulation

  Yongjun Qian, et al., bioRxiv - Molecular Biology 2022

  Quote: ... β-Actin antibody (Cell Signaling Technology, Cat. 3700, 1:10000) were used in this study ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved Caspase-7 (1:1000, Cell Signaling Technology, #8438), cleaved PARP (1:1000 ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-c-Myc (1:50, Cell Signaling Technology, #9402), and normal rabbit IgG (Cell Signaling Technology ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-total AKT (1:1000, Cell Signaling Technology, 4691), anti-phospho PAK1 (1:1000 ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho ERK (1:1000, Cell Signaling Technology, 4376), anti-total ERK (1:1000 ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-total PAK1 (1:1000, Cell Signaling Technology, 2602), anti-phospho ERK (1:1000 ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho PAK1 (1:1000, Cell Signaling Technology, 2606), anti-total PAK1 (1:1000 ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... and anti-GAPDH (1:1000, Cell Signaling Technology, 2118).
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-total ERK (1:1000, Cell Signaling Technology, 4695), anti-TET2 (1:1000 ...
• Epac1 regulates cellular SUMOylation by promoting the formation of SUMO-activating nuclear condensates

  Wenli Yang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-BMI (1:500; Cell Signaling Technology, Cat. # 6964) at 4 °C for overnight ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti c-Jun (1:150, #9165, Cell Signaling) was used as mock control antibody ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... and rabbit anti Smad3 (1:100, #9624, Cell signaling) were used for immunoprecipitation ...
• Aryl hydrocarbon receptor-dependent and -independent pathways mediate curcumin anti-aging effects

  Vanessa Brinkmann, et al., bioRxiv - Molecular Biology 2022

  Quote: ... or Nrf2 (clone D1Z9C, 1:100, Cell Signaling Technology) diluted in 1% (v/v ...
• A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

  Maria Jose Lista, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:5000 anti-mouse HRP (Cell Signaling Technology, 7076), 1:5000 anti- mouse IRDye 680RD (LI-COR ...
• Aspirin Synergizes with Regorafenib to Reduce Growth of Colorectal Cancer

  Chang Su, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 1% Phosphatase Inhibitor Cocktail (Cell Signaling Cat# 5870). Lysates were sonicated at 4°C using the Bioruptor Sonicator (Diagenode) ...
• Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

  Mokryun L. Baek, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-β-tubulin (1:1000, Cell Signaling Technology, 2146S) and horseradish peroxidase-conjugated anti-rabbit IgG H&L (1:10,000 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-H3K4me1 (5326, Cell Signaling Technology, 1:100). FPR Agonist 43 (HY-19574) ...
• Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

  Mokryun L. Baek, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-DRP1(S616) (1:1000, Cell Signaling Technology, 3455S), anti-FIS1(1:1000 ...
• In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

  Gabriel Matos-Rodrigues, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-pCHK1 (S317) (1:100, Cell Signaling Technology #2344), anti-BrdU (1:100 ...
• In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

  Gabriel Matos-Rodrigues, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-pSTAT1 (Tyr701) (1:10,000, Cell Signaling Technology #14994), anti-VINCULIN (1:10,000 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Rabbit anti-TRP63 (1:100, Cell Signaling Technology, #13109S). Chicken anti-KRT5 (1:400 ...
• Sex-Specific Role of Myostatin Signaling in Neonatal Muscle Growth, Denervation Atrophy, and Neuromuscular Contractures

  Marianne E Emmert, et al., bioRxiv - Developmental Biology 2022

  Quote: ... or DyLightTM anti-rabbit (1:5000; Cell Signaling #5151) secondary antibodies ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... pMEK (1/1000 dilution, #9121, Cell Signaling Technology, Rabbit), ppERK1/2 (E-4 ...
• Optimized Workflow for Enrichment and Identification of Biotinylated Peptides using Tamavidin 2-REV for BioID and Cell Surface Proteomics

  Kohei Nishino, et al., bioRxiv - Biochemistry 2022

  Quote: ... HRP-linked antibody (Cell Signaling Technology, #7076, 1:10,000).
• Optimized Workflow for Enrichment and Identification of Biotinylated Peptides using Tamavidin 2-REV for BioID and Cell Surface Proteomics

  Kohei Nishino, et al., bioRxiv - Biochemistry 2022

  Quote: ... HRP-linked antibody (Cell Signaling Technology, #7074, 1:10,000); anti-mouse IgG ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-pAKT (1:200, Cell Signaling Technology, #4051, AB_331158), and anti-pLATS1/2 (1:200 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-pYAP (1:200, Cell Signaling Technology, #4911, RRID:AB_2218913), anti-pAKT (1:200 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-AKT (1:200, Cell Signaling Technology, #9272, RRID:AB_329827), anti-pYAP (1:200 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Phospho-Stat1 (Tyr701) (1:500, #9167, Cell Signaling Technology), Stat1 (1:1,000 ...
• Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

  Justinn Barr, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Agr2 (1:200, Cell Signaling Technology, 13062), rabbit anti-Muc5b (1:400 ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-pJAK2 (1:500, Cat#3771, Cell Signaling Technology), anti-ERK1/2 (1:3000 ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-phosphotyrosine (1:800, Cat#9411, Cell Signaling Technology), anti-phosphoserine (1:250 ...
• TGF-β-R2 is required for HBP induced acute lung injury and vascular leakage for TGF-β/Smad/Rho signaling pathway activation

  Zixuan Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-ZO-1 (D6L1E, mAb #13663, Cell Signaling Technology), anti-RHOB (pAb A2819 ...
• Revisiting the origin of interleukin 1 (IL-1) based on biological activities of IL-1 in anamniotes and their sub-functionalization in amniotes

  Eva Hasel de Carvalho, et al., bioRxiv - Immunology 2022

  Quote: ... and 1:500 Rb-anti-HA antibody (Cell signaling) in 1% NGS/PTW over night at 4°C ...
• Two AGO proteins with transposon-derived sRNA cargo mark the germline in Arabidopsis

  Gabriele Bradamante, et al., bioRxiv - Plant Biology 2022

  Quote: ... and anti-mouse (Cell Signaling Technology #7076/1:5000) secondary antibody ...
• A role for Lin28a in aging-associated decline of adult hippocampal neurogenesis

  Zhechun Hu, et al., bioRxiv - Neuroscience 2022

  Quote: ... or rabbit-β-catenin (Cell Signaling, 8480, 1:1000) at 4°C overnight ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... Ser10 (1:200, catalog no. 9701, Cell Signaling Technology); anti-PLZF (1:100 ...
• ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

  Aaron I. Weiner, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-p63α (1:500, Cell Signaling, clone D2K8X), rabbit anti-ΔNp63 (1:100 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti-Id3 (1:200; Cell Signaling Technology, #9837); rabbit anti–HSV-TK (1:1000 ...
• Neuroprotective effects of Canagliflozin: lessons from aged genetically diverse UM-HET3 mice

  Hashan S. M. Jayarathne, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti-NeuN (1:1000 Cell Signaling #MAB377). For goat anti-Iba1 (1:1000 Abcam #ab5076 ...
• Exploring the link between Parkinson’s disease and Diabetes Mellitus in Drosophila

  Francisco José Sanz, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-phospho-JNK (Thr183/Tyr185) (1:1000, Cell Signaling) and β-actin (1:1000 ...
• Ex Vivo Validation of Six FDA-Approved Non-Receptor Tyrosine Kinase Inhibitors (NRTKIs) as Antivirals to Pandemic and Seasonal Influenza A Viruses

  Robert Meineke, et al., bioRxiv - Microbiology 2022

  Quote: ... or Stat3 (124H6) mouse mAb (1:1000) (Cell Signaling).
• The Chlamydia protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

  Karsten Meier, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse-anti-β-actin (1:2000; Cell Signaling, 3700) and HRP-conjugated mouse-anti-β-actin (1:50000 ...
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... p-ERK (Cell Signaling Technologies, Cat #4370; 1:1000), ERK1/2 (Cell Signaling Technologies ...
• Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

  Thong T. Luong, et al., bioRxiv - Genetics 2022

  Quote: ... RECQL4 (rabbit polyclonal, Cell Signaling #2814, 1:500, WB), γ-tubulin (mouse monoclonal ...
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... p-MEK (Cell Signaling Technologies, Cat #9154; 1:1000), MEK1/2 (Cell Signaling Technologies ...