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8051 - 8100 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• CCR5 closes the temporal window for memory linking

  Yang Shen, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-cFos (Cell Signaling, 9F6, #2250, 1:500), and rabbit anti-P2Y12 (AnaSpec ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-PD-1 (Cell Signaling Technology, catalog #86163). For TCR stimulation ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-S6 (S235/236) (1:1000, Cell Signaling Technology), S6 (1:1000 ...
• Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

  Santiago Naranjo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-HMGA2 (1:400, Cell Signaling Technology, #8179). For IHC staining of lung and organoid sections ...
• Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

  Amy Tarangelo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and RRM2 (Cat # 65939, Cell Signaling Technologies, 1:500). Membranes were washed three times for 10 min each in Tris buffered saline (Cat# 0788 ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-pCREB 1:1,000 (Cell Signaling Technology, 9198S).
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-ubiquitin 1:1,000 (Cell Signaling Technology, 3933S), mouse anti-ERK 1:100 (Invitrogen ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-CREB 1:1,000 (Cell Signaling Technology, 9197S), rabbit anti-pCREB 1:1,000 (Cell Signaling Technology ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-AKT 1:1,000 (Cell Signaling Technology, 9272S), rabbit anti-pAKT ...
• Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling

  Samuel Ogden, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK (Cell Signaling Technologies, 9106S, 1:2,000), anti-AKT (Cell Signaling Technologies ...
• The oncogenic Runx3–Myc axis defines p53-deficient osteosarcomagenesis

  Shohei Otani, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53 (DO-1, MBL, 1C12, Cell Signaling Technology), anti-p21 (EPR3993 ...
• Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling

  Samuel Ogden, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-AKT (Cell Signaling Technologies, 4060S, 1:2,000), anti-HNF4A (R&D Systems ...
• Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243A>G mtDNA mutation

  Chih-Yao Chung, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p-S6 (1:3000, Cell Signaling Technology #4858), anti-S6 (1:3000 ...
• Extracellular vesicles from neuronal cells promote neural induction of mESCs through cyclinD1

  Lu Song, Xinran Tian, Randy Schekman, bioRxiv - Cell Biology 2021

  Quote: ... anti-HA (1:1,000; Cell Signaling Technology, Danvers, MA).
• MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

  Elyne Backx, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK (9101S, Cell Signaling Technology, 1/1000) and anti-total ERK (4695 ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-GSK-3β (Cell Signaling Technology, 5558, 1:2000), GSK-3β (Cell Signaling Technology ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-β-catenin (Cell Signaling Technology, 9561, 1:500), β-actin (Cell Signaling Technology ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit polyclonal eIF4A1 (Cell Signaling Technologies, 2490, 1:1000), eIF4B (1F5 ...
• The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

  Mena Abdel-Nour, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-cleaved PARP (#9546, Cell Signaling, 1/1,000), rabbit anti-GFP (#ab290 ...
• Phosphatidylinositol 4-kinase III beta regulates cell shape, migration and Focal Adhesion number

  Patricia Bilodeau, et al., bioRxiv - Cell Biology 2020

  Quote: ... tubulin (1:1000, Cell Signaling Technology 3873; Whitby, Canada), mouse α-FAK (1:200 Thermo Fisher #396500) ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-VASP (1:100; Cell Signaling Technology #3132S), mouse anti-ZO-1 (1:1000 ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-VASP (1:1000; Cell Signaling Technology #3132S) and rabbit-myosin light chain (1:1000 ...
• Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling

  Keng Hou Mak, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-S6K (1:1000, cat# 9202, Cell Signaling Technology), and β-actin (1:5,000 ...
• AdipoR2 is Essential for Membrane Lipid Homeostasis in Response to Dietary Saturated Fats

  Ranjan Devkota, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit monoclonal anti-GAPDH (14C10, 1:1000, Cell Signaling).
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-c-Jun S63 (#9261S, 1:1000, Cell Signaling), c-Jun (#9165S ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-MET Y1234/1235 (#3077S, 1:1000, Cell Signaling), MET (#8198S ...
• Subcellular localization of glypican-5 associates with dynamic cell motility and cell communication of the human mesenchymal stem cell line U3DT

  Masao Takeuchi, et al., bioRxiv - Cell Biology 2019

  Quote: ... Anti-FGFR-1 (D8E4) XP Rabbit mAb (Cell Signaling). Alexa Fluor 488 conjugated-anti-mouse IgG(H+L) ...
• Widespread non-apoptotic activation of Drosophila Caspase-2/9 limits JNK signaling, macrophage proliferation, and growth of wound-like tumors

  Derek Cui Xu, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-HA-tag (1:1000, Cell Signaling, RRID:AB_1549585), rabbit anti-Phospho-histone H3 (1:100 ...
• Inhibitors of the Bub1 spindle assembly checkpoint kinase: Synthesis of BAY-320 and comparison with 2OH-BNPP1

  Ilma Amalina, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-GFP (Cell Signaling cat#2956, 1:1000); sheep anti-Tao154 (1:1,000) ...
• SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors

  Giulio Giuliani, et al., bioRxiv - Cell Biology 2020

  Quote: ... and rabbit Ki-67 1:400 (Cell Signaling 9129). For CD140a immunolabelling ...
• Amelioration of DSS-induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22

  Suhyun Kim, et al., bioRxiv - Immunology 2021

  Quote: ... Mouse anti-STAT3 (1:1000, Cell Signaling Technology, USA), mouse anti-pSTAT3 (Tyr705 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... p-TBK1 (Ser172) ( Cell Signaling, no. CST5483; 1:1000); and β-actin (Sigma-Aldrich ...
• Synaptotagmin 2 is ectopically overexpressed in excitatory presynapses of a widely used CaMKIIα-Cre mouse line

  Ken Matsuura, et al., bioRxiv - Genetics 2021

  Quote: ... RpAb to Cre (1:1000) from Cell Signaling (15036S), and MmAb to α-tubulin (1:1000 ...
• Sex hormones underlying 17a-Estradiol effects on neuroinflammation

  Lucas K. Debarba, et al., bioRxiv - Neuroscience 2020

  Quote: ... and rabbit anti pS6 (1:100 Cell signaling, MA) immunostaining ...
• Sobp modulates Six1 transcriptional activation and is required during craniofacial development

  Andre L. P. Tavares, et al., bioRxiv - Developmental Biology 2021

  Quote: ... or mouse anti-HA (6E2, Cell Signaling, 1:800) followed by Alexa Fluor 488-conjugated anti-rabbit (4412 ...
• BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

  Alexandra M. Young, et al., bioRxiv - Cell Biology 2020

  Quote: Rabbit anti-HSP90 (1:5000; 4874; Cell Signaling Technology)
• A calcineurin-mediated scaling mechanism that controls a K⁺-leak channel to regulate morphogen and growth factor transcription

  Chao Yi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Anti-β-catenin (1:1000, Cell Signaling Technology, 9562L), Anti-β-Actin pAb-HRP-DirecT (1:2000 ...
• Elucidating the crosstalk between inflammation and DNA damage pathways in the pancreatic beta-cell through the diabetes susceptibility gene, TCF19

  Grace H. Yang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... phospho-NF-κB p65 (93H1, Cell Signaling 1:1000), IRF1 (D5E4 ...
• NLRP3 inflammasome priming and activation are regulated by a novel phosphatidylinositol-dependent mechanism

  Claire Hamilton, et al., bioRxiv - Immunology 2021

  Quote: ... phospho-p70-S6K1 (1:1,000; 9234; Cell Signaling Technology), TIRAP (1:1000 ...
• MDA5 is an essential vita-PAMP sensor necessary for host resistance against Aspergillus fumigatus

  Xi Wang, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-pSTAT1 (Cell Signaling, #7649P, 1/1000 dilution), and rabbit anti-β-actin (Abcam ...
• Production of human translation-competent lysates using dual centrifugation

  Lukas-Adrian Gurzeler, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Phospho-eIF2α (Ser51) (Cell signaling Technology 9721, 1:1,000), Renilla luciferase (Thermo Fisher Scientific ...
• Opposing roles of p38α-mediated phosphorylation and arginine methylation in driving TDP-43 proteinopathy

  Mari Aikio, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit PRMT1 (A33) (1:1,500; 2449, Cell Signaling Technology), mouse GAPDH (1:10,000 ...
• Primary cilia drive postnatal tidemark patterning in articular cartilage by coordinating responses to Indian Hedgehog and mechanical load

  Danielle Rux, et al., bioRxiv - Developmental Biology 2021

  Quote: ... pSmad2 (1:1500, Cell Signaling Technology, 3108S, Danvers, MA) or pSmad159 (1:800 ...
• Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich’s ataxia patient cells

  G Vilema-Enríquez, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit monoclonal anti-EZH2 (Cell signaling #5246 1/2500), rabbit polyclonal anti-DOT1L (Abcam ab72454 ...
• Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich’s ataxia patient cells

  G Vilema-Enríquez, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit polyclonal anti-G9a (Cell signaling #3306 1/5000), rabbit monoclonal anti-EZH1 (Cell signaling #42088 1/1000) ...
• Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich’s ataxia patient cells

  G Vilema-Enríquez, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit monoclonal anti-EZH1 (Cell signaling #42088 1/1000), rabbit monoclonal anti-EZH2 (Cell signaling #5246 1/2500) ...
• Dynamic adult tracheal plasticity drives stem cell adaptation to changes in intestinal homeostasis

  Jessica Perochon, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-p-Erk 1:100 (Cell Signaling, #9101), guinea pig anti-Myc 1:100 (gift from Gines Morata ...
• Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues

  Nathaniel Kastan, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Anti-Sox-9 (1:100, Rb Cell Signaling 82630) was used to mark Müller cells ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... phosphorylated P38-MAPK (D3F9, 1:1000, Cell Signaling Technology), ERK1/2 (9102 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and phosphorylated FAK (8556, 1:1000, Cell Signaling Technology). Expression of α-tubulin (CP06 ...