Labshake search

7251 - 7300 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway

  Timothy T Nguyen, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and TFAP2B (2509S, Cell Signaling Technology; 1:25 dilution). After washing with PBSTx ...
• Lymphotoxin-β Promotes Bone Colonization and Osteolytic Outgrowth of Indolent Bone Metastatic cells of Breast Cancer

  Xuxiang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... α-AKT (1:1,000 dilution, Cell Signaling Technology, Cat# 4691). Secondary antibodies used in experiments were included as following ...
• MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed

  Xuanyu Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... cleaved caspase-3 (rabbit IgG, 1:1000, Cell Signaling), and DCX (guinea pig IgG ...
• NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

  Abrar Choudhury, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibodies recognizing NOTCH3 (5276, Cell Signaling, 1:1000) or GAPDH (8245 ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ser235/236-pS6 (1:1,000; Cell Signaling Technology #4858), S6 Ribosomal Protein (1:1,000 ...
• Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling

  Aarathy Ravi Sundar Jose Geetha, et al., bioRxiv - Immunology 2023

  Quote: ... Phospho-STAT1 (Tyr701; Cell signaling, Catalog # 9167, 1:1000), IRF9 (6F1 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Hsp70 (dilution 1/500; Cell Signaling Technology; D69), anti CD63 (dilution 1/500 ...
• FMRP-Regulated Alternative Splicing is Multifactorial and Resembles Splicing Control by MBNL1

  Suna Jung, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-GAPDH antibody (Cell signaling technology, 2118, 1:1,000), anti-alpha-Tubulin (MilliporeSigma ...
• NSC95397 is a Novel HIV Latency Reversing Agent

  Randilea Nichols Doyle, et al., bioRxiv - Microbiology 2023

  Quote: ... or rabbit anti-53BP1 (Cell Signaling S1778, 1:2000) overnight at 4°C ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... HA-Tag (Cell Signaling; catalog no. 3724; 1:500); K10 (BioLegend ...
• Inhibition of autophagy as a novel therapy for the treatment of neurofibromatosis type 1 tumors

  M. Stevens, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-PARP (rabbit, Cell Signaling 952, 1:1000). Secondary antibodies used were anti-mouse Alexa Fluor Plus 800 (goat ...
• Cross-species analysis of ARPP19 phosphorylation during oocyte meiotic maturation charts the emergence of a new cAMP-dependent role in vertebrates

  Ferdinand Meneau, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... and phosphorylated-PKA substrates (1:1000, Cell Signaling 9624). After overnight incubation at 4°C ...
• The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions

  Lin Xie, et al., bioRxiv - Cell Biology 2023

  Quote: ... HRP-linked Antibody (Cell Signaling technology, 7076S, 1:4000).
• Robust axis elongation by Nodal-dependent restriction of BMP signaling

  Alexandra Schauer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... α-pSmad5 (1:100, cat.no. 9516S, Cell Signaling Technology) whole mount immunofluorescence was performed as described (Pomreinke et al ...
• Th17 cells target the metabolic miR-142-5p-SDHC/SDHD axis promoting invasiveness and progression of cervical cancers

  Maike Pohlers, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-e-cadherin (1:1000; AB_2728770; Cell Signaling), rabbit anti-vimentin (1:1000 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD11C: 1:100 (Cell Signaling Technology Cat# 39143, RRID:AB_2924836); CD86 (Cell Signaling Technology Cat# 19589 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... AKT 1:1000 (Cell Signaling Technology Cat# 9272, RRID:AB_329827), phospho-ERK 1/2 Y202/204 1:2000 (Cell Signaling Technology Cat# 4370 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Vinculin 1:1000 (Cell Signaling Technology Cat# 13901, RRID:AB_2728768), CDK9 1:1000 (Cell Signaling Technology Cat# 2316 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PTEN 1:1000 (Cell Signaling Technology Cat# 9552, RRID:AB_10694066).
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK 1:1000 (Cell Signaling Technology Cat# 4695, RRID:AB_390779), phospho-PAK 1/2 S199/204 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH 1:1000 (Cell Signaling Technology Cat# 2118, RRID:AB_561053), Vinculin 1:1000 (Cell Signaling Technology Cat# 13901 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CDK9 1:1000 (Cell Signaling Technology Cat# 2316, RRID:AB_2291505), phospho-RNA Polymerase II S2 1:1000 (Millipore Cat# 04-1571 ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... Ubiquitin (Cat. no: 3933, Cell Signaling Technology, 1:1000), HO1 (cat no ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... LC3 (cat. no. 2775, Cell Signaling Technology; 1:2000), phospho-p62 (cat ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... KEAP1 (Cell Signaling Technology, cat no #4678, 1:1000), Nrf2 antibody (Santa Cruz biotechnology ...
• Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

  Rukmini Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (cat. no. 2118, Cell Signaling Technology; 1:2000), Myc beads (cat ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... E-Cadherin (24E10, Cell Signaling Technology, dilution 1:1000), Polycystin 2 antibody was provided by the Baltimore Polycystic Kidney Disease (PKD ...
• Stress-induced vascular remodeling: novel insight into the role of omega-3 fatty acid metabolite, 4-oxoDHA

  Makoto Nishimori, et al., bioRxiv - Biochemistry 2023

  Quote: ... and rabbit anti-PCNA (1:1000, Cell Signaling, #D3H8P) were used ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ser139-pHistone H2A.X (1:1,000; Cell Signaling Technology #9718), 4-Hydroxynonenal (1:500;Abcamab46545) ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... S6 Ribosomal Protein (1:1,000; Cell Signaling Technology #2217), Thr37/46-p4EBP1 (1:1,000 ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ser235/236-pS6 (1:200; Cell Signaling Technology #4858), Ser139-pHistone H2A.X (1:1,000 ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Thr37/46-p4EBP1 (1:1,000; Cell Signaling Technology #2855), Cleaved Caspase-3 (1:1,000 ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... E-cadherin (Cell Signaling; catalog no. 3195S; 1:1000). The secondary antibody used was Anti-rabbit IgG HRP linked (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... pCREB(Ser133) (Cell Signaling; catalog no. 9198; 1:1000), E-cadherin (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... pAKT(Ser473) (Cell Signaling; catalog no. 4060; 1:1000), AKT (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... pAKT(Thr308) (Cell Signaling; catalog no. 13038; 1:1000), pAKT(Ser473 ...
• NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

  Ken Takashima, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Cyclin B1 (#12231, Cell Signaling Technology, 1:1000), anti-Cyclin E1(#20808 ...
• NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

  Ken Takashima, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Cyclin A2 (#91500, Cell Signaling Technology, 1:1000), anti-Cyclin B1 (#12231 ...
• NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

  Ken Takashima, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-EZH2 (D2C9, Cell Signaling Technology, 1:1000), anti-EED (05-1320 ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-JNK (Cell Signaling Technology, #9252, 1:1,000 dilution), anti-p-ERK1/2 (Santa Cruz Biotechnology ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ... c-MYC 1:100 (Cell Signaling Technology, Cat 18583), H3K4me3 1:50 (Cell Signaling Technology ...
• Translational approach to social isolation during a global pandemic: Hippocampal somatic mutation

  Bomee Lee, et al., bioRxiv - Neuroscience 2023

  Quote: ... DCX antibody (1:1000, Cell Signaling Technology, rabbit, #4604), MAP2 antibody (1:1000 ...
• Translational approach to social isolation during a global pandemic: Hippocampal somatic mutation

  Bomee Lee, et al., bioRxiv - Neuroscience 2023

  Quote: ... NeuN antibody (1:1000, Cell Signaling Technology, rabbit, #24307), Erk antibody (1:1000 ...
• Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, and abnormal fatty acid metabolism

  Mariana I. Tsap, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Cas3 (#9662, 1:1000) from Cell Signaling; and rabbit anti-NrxIV (1:1000 from Christian Klämbt) ...
• Retinoid X Receptor activation prevents diabetic retinopathy in murine models

  Iuliia Dorofeeva, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-AMPK (Cell signaling, #5832S, dilution 1:1000) antibodies were used for target protein detection.
• IL-1Ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology

  Reilly L. Allison, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-NFkB p65 (Cell Signaling, #6956, 1:1000) rabbit anti-phNFkB (Cell Signaling ...
• Genetic dissection of BDNF and TrkB expression in glial cells

  Changran Niu, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-GFAP (1:500; Cell Signaling Technology #3670S), mouse anti-Olig2 (1:250 ...
• PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

  Payam Gharibani, et al., bioRxiv - Neuroscience 2023

  Quote: ... either with rabbit anti-Arg1 (1:100, Cell Signaling) or mouse anti-iNOS (1:200 ...
• Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture

  Natalia Akulenko, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-HA (1:300, 6E2, Cell Signaling, #2367), rabbit anti-HA (1:500 ...
• Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture

  Natalia Akulenko, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-HA (1:500, C29F4, Cell Signaling, #3724).