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7051 - 7100 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• lincRNA RP24-315D19.10 promotes endometrial decidualization via upregulation of hnRNPA2B1

  Liping Tan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit monoclonal anti-Bcl2 (1:1,000; Cell Signaling Technology), rabbit polyclonal anti-hnRNPA2B1 (1:5000 ...
• lincRNA RP24-315D19.10 promotes endometrial decidualization via upregulation of hnRNPA2B1

  Liping Tan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit monoclonal anti-Bax (1:1000; Cell Signaling Technology), rabbit monoclonal anti-Bcl2 (1:1,000 ...
• Effectors enabling adaptation to mitochondrial complex I loss in Hürthle cell carcinoma

  Raj K. Gopal, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved caspase-3 (Asp175; Cell Signaling #9661S, 1:100), and 4-HNE (Abcam ab46545 ...
• Calpain-mediated proteolysis of vimentin filaments is augmented in Giant Axonal Neuropathy (GAN) fibroblasts exposed to hypotonic stress

  Cassandra L. Phillips, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Calpastatin (Cell Signaling Technology, WB 1:1000), rabbit anti-Calpain 1 (Cell Signaling Technology ...
• RUNX1 is regulated by androgen receptor to promote cancer stem markers and chemotherapy resistance in triple negative breast cancer

  Natalia B Fernández, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-RUNX1 (1:1000 dilution; Cell Signaling Technology #4334), anti-SOX4 (1:1000 dilution ...
• RGG-motif proteins regulate mRNA translation upon genotoxic stress

  Raju Roy, et al., bioRxiv - Cell Biology 2022

  Quote: ... for eIF4G (rabbit, 2498; Cell Signaling Technology, 1:200); for EIF4E (mouse ...
• RGG-motif proteins regulate mRNA translation upon genotoxic stress

  Raju Roy, et al., bioRxiv - Cell Biology 2022

  Quote: ... for EIF4E (mouse, 9742, Cell Signaling Technology, 1:200). PLA minus and PLA plus probes (containing the secondary antibodies conjugated to oligonucleotides ...
• MND1 enables repair of two-ended DNA double-strand breaks

  Lisa Koob, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-pCHK1 ser345 (2344, Cell Signaling, 1:500 WB), anti-pCHK2 thr68 (2661 ...
• MND1 enables repair of two-ended DNA double-strand breaks

  Lisa Koob, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-pCHK2 thr68 (2661, Cell Signaling, 1:1000 WB), anti-GFP (11 814 460 001 ...
• MND1 enables repair of two-ended DNA double-strand breaks

  Lisa Koob, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-pATM ser1981 (#4526, Cell Signaling, 1:1000 WB).
• Presenilin-dependent regulation of tau pathology via the autophagy/proteasome pathway

  Anna del Ser-Badia, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-phosphorylated GSK3β (Ser9, 1:1000; Cell Signaling), goat anti-Akt (1:1000 ...
• Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries

  Marangelie Criado-Marrero, et al., bioRxiv - Neuroscience 2024

  Quote: ... and anti-GFAP (GA5) (1:1000, CS3670S, Cell Signaling) antibodies followed by 30 min incubation with biotinylated secondary antibodies ...
• Chemogenetic activation of microglial Gi signaling decreases microglial surveillance and impairs neuronal synchronization

  Shunyi Zhao, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-GFAP (1:500, Cell Signaling Technology, 3670S), mouse anti-CC1 (1:200 ...
• Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis

  Rosana-Bristena Ionescu, et al., bioRxiv - Neuroscience 2024

  Quote: ... or anti-mouse (Cell Signaling, Cat#7076, 1:2000). Membranes were washed three times with TBST for 5 minutes ...
• Translational response to mitochondrial stresses is orchestrated by tRNA modifications

  Sherif Rashad, et al., bioRxiv - Molecular Biology 2024

  Quote: - P70S6K antibody (1:1000 dilution, Cell signaling, Cat# 9202).
• Translational response to mitochondrial stresses is orchestrated by tRNA modifications

  Sherif Rashad, et al., bioRxiv - Molecular Biology 2024

  Quote: - Mouse IgG (1:1000 dilution, Cell signaling, Cat# 7076S).
• Translational response to mitochondrial stresses is orchestrated by tRNA modifications

  Sherif Rashad, et al., bioRxiv - Molecular Biology 2024

  Quote: - P38 antibody (1:1000 dilution, Cell signaling, Cat# 9212).
• Proteome-scale tagging and functional screening in mammalian cells by ORFtag

  Filip Nemčko, et al., bioRxiv - Systems Biology 2024

  Quote: ... or HRP-α-Rabbit (Cell Signaling, 7074, 1:10,000) as secondary antibody and imaged using ClarityTM Western ECL Substrate (BioRad ...
• Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren’s disease

  Ga-Yeon Son, et al., bioRxiv - Physiology 2024

  Quote: ... and rabbit anti-GAPDH (1:1000, 21185, Cell Signaling). Tris-buffered saline (1706435 ...
• Fabry Cardiomyopathy: Myocardial Fibrosis, Inflammation and Down-Regulation of Mannose6Phosphate Receptors cause Low accessibility to Enzyme Replacement Therapy

  Andrea Frustaci, et al., bioRxiv - Pathology 2023

  Quote: ... (D8Z3J) polyclonal antibody (1:1000, Cell Signaling Technolo-gy). Anti-α-sarcomeric actin antibody (1:500 ...
• D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability

  Gergely Rona, et al., bioRxiv - Cell Biology 2024

  Quote: pRB (S807/811) (1:1000, Cell Signaling Technology 8516S)
• Mechanical cues of extracellular matrix determine tumor innervation

  Shu-Heng Jiang, et al., bioRxiv - Neuroscience 2024

  Quote: ... cleaved caspase 3 (#9661, Cell Signaling Technology, 1:400), CD45 (ab40763 ...
• Translational response to mitochondrial stresses is orchestrated by tRNA modifications

  Sherif Rashad, et al., bioRxiv - Molecular Biology 2024

  Quote: - EIF2a antibody (1:1000 dilution, Cell signaling, Cat# 9722).
• Local ecdysone synthesis in a wounded epithelium sustains developmental delay and promotes regeneration in Drosophila

  Douglas Terry, Colby Schweibenz, Kenneth Moberg, bioRxiv - Developmental Biology 2024

  Quote: ... and anti-Phospho-histone H3 (Cell Signaling; 1:100). Fluorescently labeled secondary antibodies were from Jackson Immunoresearch Laboratories (1:50) ...
• Polygenic Risk for Alcohol Use Disorder Affects Cellular Responses to Ethanol Exposure in a Human Microglial Cell Model

  Xindi Li, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-human PU.1 (Cell Signaling Technology, 2266S), rabbit anti-human CX3CR1 (Biorad ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... EEA1 (1:200; C45B10; 3288; Cell Signaling Technology Inc.); RAB7 (1:100 ...
• D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability

  Gergely Rona, et al., bioRxiv - Cell Biology 2024

  Quote: Cleaved Caspase-3 (1:1000, Cell Signaling Technology 9661S)
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-BRD7 (D9K2T) (Cell Signaling #15125, 1:1000), Rabbit Anti-SMARCD1 (E7W9W ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-BICRA (E6I3A) (Cell Signaling #45441, 1:1000), Rabbit Anti-BICRAL (GLTSCR1L ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-H3K27Ac (Cell Signaling D5E4, #8173, 1:100).
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-SMARCD1 (E7W9W) (Cell Signaling #35070, 1:1000), Rabbit Anti-BICRA (E6I3A ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-HA (C29F4) (Cell Signaling #3724T, 1:1000) or Mouse Anti-HA.11 (16B12 ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse anti-Rpb1 (Cell Signaling 4H8, #2629, 1:50), Rabbit Anti-H3K27Ac (Cell Signaling D5E4 ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit anti-BRD9 (E9R2I) (Cell Signaling #58906, 1:1000), Rabbit Anti-BRD7 (D9K2T ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-OCA-T1 (Cell Signaling #20217, 1:1000), Rabbit Anti-SMARCA2 (BRM ...
• Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

  Leslie Duplaquet, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-ACTL6B (E5X8C) (Cell Signaling #46787S, 1:1000), mouse α-INSM1 (Santa Cruz ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... RAB11 (1:100; D4F5; 5589; Cell Signaling Technology Inc.) and Myosin ID (1:500 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... RAB7 (1:100; D95F2; 9367; Cell Signaling Technology Inc.); RAB4 (1:200 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... PDGFRβ (1:1000; 28E1; 3169; Cell Signaling Technology, Inc.); β-tubulin (1:1000 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... APPL1 (1:200; D83H4; 3858; Cell Signaling Technology Inc.); EEA1 (1:200 ...
• Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

  Corey D. Holman, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and anti-PLIN1 (rabbit, 1:200 Cell Signaling #3470). Slides were imaged on an inverted fluorescence microscope (Keyence BZ-X710) ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... RAB5 (1:200; C8B1; 3547; Cell Signaling Technology Inc.); APPL1 (1:200 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... PDGFRβ (1:1000; 28E1; 3169; Cell Signaling Technology, Inc.); Na+/K+-ATPase (1:500 ...
• Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

  Namsuk Kim, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and anti-β-Actin (1:5000, 5125S, Cell Signaling).
• AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress

  Manuel A. Torres Acosta, et al., bioRxiv - Immunology 2023

  Quote: ... 1:50 anti-AMPKα (Cell Signaling cat. no. 2532S), and 1:50 anti-β-actin (Abcam cat ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho-S6 Ser240/244 (#5364, 1:1,000; Cell Signaling), S6 (#2217 ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho-4E-BP1 Ser65 (#9451, 1:1,000; Cell Signaling), 4E-BP1/2 (#2845 ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho-S6 Ser235/236 (#4858, 1:1,000; Cell Signaling), phospho-S6 Ser240/244 (#5364 ...
• Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency

  Chihiro Andoh, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-STAT6 (1:1000, #5397, Cell Signaling Thechnology), mouse anti-GAPDH (1:1000 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... p-T308 AKT (1:1,000; Cell Signaling Technology # 2965), AKT (1:1,000 ...