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651 - 700 of 2267 citations for 5 Bromo 2 Tert Butyldimethylsilyl 4 Methylthiazole since 2020

• HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness in Medulloblastoma

  Mariane da Cunha Jaeger, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Phospho-p44/42 MAPK (pErk1/2, 1:2000; Cell Signaling), p44/42 MAPK (Erk1/2 ...
• RAS specific protease Induces Irreversible Growth Arrest via p27 in several KRAS Mutant Colorectal Cancer cell lines

  Caleb K. Stubbs, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p44/42 MAPK (ERK1/2, Cell Signaling Technology #4696), anti-HB-EGF (R&D Systems ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-ERK1/2 T202/Y204 (#4370S, 1:1000, Cell Signaling), ERK1/2 (#4695S ...
• Extracellular Superoxide Dismutase (EC-SOD) Regulates Gene Methylation and Cardiac Fibrosis During Chronic Hypoxic Stress

  Ayan Rajgarhia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ERK 1/2 (Cell Signaling Technology, Danvers, MA, USA)
• Wnt-dependent activation of ERK mediates repression of chondrocyte fate during calvarial development

  Beatriz Ibarra, Cody Machen, Radhika P. Atit, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (1:1250, Cell Signaling 4370). Wide-field images were captured at 20X and 40X using the Leica DMi8 inverted microscope using the Leica Application Suite X (LASX ...
• Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia

  L. Martin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phosphorylated Erk1-2 (Thr180/Tyr182) (Cell Signaling Technology, #4370), anti-total Erk1-2 (Sigma-Aldrich ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:1000), Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102; 1:1000), Mouse anti-ß-Actin (Cell Signaling Technology # 58169 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:300), Rabbit anti-phosphor (s235/236)-S6 (Cell Signaling Technology # 4858 ...
• The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer

  Rhona Millar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... lnti-phospho-ERK1/2 (250ng/mL, Cell Signaling Technology, #4370); anti-ERK1/2 (84ng/mL ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-Phospho-ERK1/2(Thr202/Tyr204) (#9101, Cell Signaling), 1:1000 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-Phospho-MEK1/2(Ser217/221) (#9121, Cell Signaling), 1:1000 ...
• The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response

  Sarayut Phasuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-total ERK1/2 (1:1000; Cell Signaling, Danvers, MA), anti-PSD95 (1:2000 ...
• The Imprinted Igf2-Igf2r Axis is Critical for Matching Placental Microvasculature Expansion to Fetal Growth

  Ionel Sandovici, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling, 9102), rabbit anti-Phospho-Akt (Ser473 ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-ERK1/2 pT202/pY204 (Cell Signaling Technology, catalog #9106), anti-Grb2 (Cell Signaling Technology ...
• Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation

  Adele Stewart, et al., bioRxiv - Neuroscience 2021

  Quote: ... and phospho-ERK 1/2 (Cell Signaling, RRID:AB_331646; 1:1000).) ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling, 9102s, 1:1000), MITF (Cell Signaling ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4695S), anti-H2AK119Ub1 antibody (1:2000 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Phospho-MEK1/2 (9154S, Cell Signaling; WB, 1:1000), anti-MEK1/2 (ab178876 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and pLATS1/2 (1:500, Cell Signaling Technology, #8654, RRID:AB_10971635) and Cytochrome P450 2E1 (1:500 ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-pERK1/2 (1:5000, Cat#9101, Cell Signaling Technology), anti-PTPN12 (1:500 ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-ERK1/2 (1:3000, Cat#4695, Cell Signaling Technology), anti-pERK1/2 (1:5000 ...
• Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress

  Laura Virtanen, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit monoclonal pERK1/2 (1:1000, D13.14.4E, Cell Signaling Technologies), rabbit monoclonal cleaved PARP-1 (1:1000 ...
• Aberrant mechanosensitive signaling underlies activation of vascular endothelial xanthine oxidoreductase that promotes aortic aneurysm formation in Marfan syndrome

  Hiroki Yagi, et al., bioRxiv - Pathology 2022

  Quote: ... rabbit polyclonal anti-ERK1/2 antibody (Cell Signaling Technology, #9102), rabbit monoclonal anti-phosphorylated p38 MAPK antibody (Thr180/Tyr182 ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phospho ERK1/2 (Cell Signaling technology; #4376, 1:1,000), anti-ERK1/2 (Cell Signaling technology ...
• A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

  Han-Soo Kim, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... ERK 1/2 from Cell Signaling Technology (Danver, MA, USA). All antibodies were diluted to 1:1000 v/v in 5% BSA in DPBS (Welgene).
• Sortilin exhibits tumor suppressor-like activity by limiting EGFR transducing function

  E. Lapeyronnie, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pERK1/2 (Thr202/Thr204, #4370, 1:1000 dilution, Cell Signaling), ERK1/2 (#9102 ...
• Epigenetic plasticity via adaptive DNA hypermethylation and clonal expansion underlie resistance to oncogenic pathway inhibition in pancreatic cancer

  Laura K. Godfrey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p-ERK1/2 (#4376, RRID:AB_331772, Cell Signaling Technology, 1:15), Vinculin (#13901 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho(Thr44/Tyr42)-ERK1/2 (1:1000; 9101; Cell Signaling), Erk1/2 (1:1000 ...
• ASPP2/PP1 complexes maintain the integrity of pseudostratified epithelia undergoing remodelling during morphogenesis

  Christophe Royer, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-phospho-Myosin light chain 2 (Cell Signaling, #3674), 1:100 ...
• SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells

  Yuichiro J. Suzuki, et al., bioRxiv - Pathology 2020

  Quote: ... the mouse anti-MEK1/2 antibody (Catalog #4694; Cell Signaling), the rabbit anti-phospho-Akt (Ser473 ...
• Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

  Li Wang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 6-diamidino-2-phenylindole (DAPI; Cell Signaling; Catalog No. 8961S). All images were captured on a Zeiss Apotome 2 microscope by using 20x ...
• Carbamazepine restores neuronal signaling, protein synthesis and cognitive function in a mouse model of fragile X syndrome

  Qi Ding, Fan Zhang, Yue Feng, Hongbing Wang, bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-pERK1/2 (Cell Signaling, Cat#9101, 1:2000), rabbit anti-Akt (Cell Signaling ...
• Carbamazepine restores neuronal signaling, protein synthesis and cognitive function in a mouse model of fragile X syndrome

  Qi Ding, Fan Zhang, Yue Feng, Hongbing Wang, bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling, Cat#9102, 1:1000), rabbit anti-pERK1/2 (Cell Signaling ...
• V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

  Miriam Formica, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-ERK 1/2 1:1000 (4695, Cell Signaling). Western blots protein levels were analyzed using Image Lab (Biorad).
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti p-Erk1/2(T202/Y204) (Cell Signaling Technology, #4370), anti Erk1/2(Cell Signaling Technology ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... p-ERK1/2 (T202/Y204, Cell Signaling, 4377, 1:2,000), GAPDH (Cell Signaling ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-phospho ERK1/2 (Cell signaling technology; #4376, 1:100) antibodies were used for immunostaining ...
• Addressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation

  Xiaotong Zhu, et al., bioRxiv - Biochemistry 2021

  Quote: ... Anti-Phospho-Erk1/2 (Cell signaling technology, cat. no. 4370); anti-Erk1/2 (Cell signaling technology ...
• THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development

  Jiali Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-phospho-ERK1/2 (Thr202/Tyr204, Cell Signaling Technology, 92711), anti-SHP1 (Santa Cruz ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PAK1/2/3 (Cell Signaling 2604, 1:1000), rabbit anti-phospho-Cofilin (S3 ...
• Sex differences in cardio-pulmonary pathology of SARS-CoV2 infected and Trypanosoma cruzi co-infected mice

  Dhanya Dhanyalayam, et al., bioRxiv - Pathology 2021

  Quote: ... Hexokinase 2-specific rabbit monoclonal antibody (#2867S, Cell Signaling Technology), β1 adrenergic receptor-specific rabbit polyclonal antibody (#12271S ...
• ADAP1 promotes latent HIV-1 reactivation by selectively tuning a T cell signaling-transcriptional axis

  Nora-Guadalupe P. Ramirez, et al., bioRxiv - Microbiology 2021

  Quote: Anti-phos-ERK1/2 Thr202/Tyr204 (Cell Signaling Technology, 4370) (1:1000 ...
• LPA/PKD-1 signaling promotes development of arteriolar niche that supports self-renewal of breast cancer stem cells and stemness

  Yinan Jiang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and human/mouse Erk (1/2) (137F5) (Cell Signaling Technology), ALDH1A1 (AF5869 ...
• Long-lasting tagging of neurons activated by seizures or cocaine administration in Egr1-CreER^T2 transgenic mice

  Sophie Longueville, et al., bioRxiv - Neuroscience 2020

  Quote: ... phospho-ERK1/2 (Thr202/204) (1:1000, #9101, Cell Signaling), Fos (1:1000 ...
• SCARF1-induced efferocytosis plays an immunomodulatory role in humans, and autoantibodies targeting SCARF1 are produced in patients with systemic lupus erythematosus

  April M. Jorge, et al., bioRxiv - Immunology 2021

  Quote: ... Erk1/ 2 p-44/42-Alexa488 (Cell Signaling clone 137F5), and MAPK p38-Alexa488 (Thr180/Tyr182 ...
• Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

  Hope E. Burks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... The MEK1/2 inhibitor (U0126) was purchased from Cell Signaling and used at a 5 μM final concentration ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-ERK1/2 T202/Y204 (Cell Signaling, #9106, 1:1000), GAPDH (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-MEK1/2 S217/221 (Cell Signaling, #9121, 1:1000). Protein bands were visualized using IRDye-labeled secondary antibodies at dilution 1:40000 (LI-COR Biotechnology ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-p44/42 (ERK1/2) (1:1000, 137F5, Cell Signaling), anti-IκBα (1:1000 ...