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551 - 600 of 2267 citations for 5 Bromo 2 Tert Butyldimethylsilyl 4 Methylthiazole since 2020

• ADAP1 promotes latent HIV-1 reactivation by selectively tuning a T cell signaling-transcriptional axis

  Nora-Guadalupe P. Ramirez, et al., bioRxiv - Microbiology 2021

  Quote: ... Anti-ERK1/2 (Cell Signaling Technology, 4696 or 4695) (1:2000)
• Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma

  Arwin Groenewoud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-SLC7A11 and anti-ERK1/2 (Cell Signaling Technology), anti-di-phospho-ERK and anti-Vinculin (Sigma-Aldrich).
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho Myosin Light Chain 2 (Cell Signaling #3671), anti-Myosin Light Chain 2(Cell Signaling #3672) ...
• Pro-tumor and prothrombotic activities of hepsin in colorectal cancer cells and suppression by venetoclax

  Maria Carmen Rodenas, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (9101S, Cell Signaling Technologies, Werfen, Barcelona, Spain), pSTAT3(Tyr705 ...
• Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease

  Brett K. Fulleylove-Krause, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-SIRT 2 (Cell Signaling, 12672, 1:1000), rabbit anti-SIRT 3 (Abgent ...
• Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes

  Sabrina Contino, et al., bioRxiv - Neuroscience 2020

  Quote: ... Anti-Presenilin 2 (1:1,000; Cell Signaling, Danvers, USA); Anti-Tubulin (1:3000 ...
• Addressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation

  Xiaotong Zhu, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-Erk1/2 (Cell signaling technology, cat. no. 4695).
• Hydroxylation of Actin Impairs Cell Motility Through Blocking its’ Histidine Methylation

  Zhenzhen Zi, et al., bioRxiv - Biochemistry 2021

  Quote: ... PHD-2/Egln1 (D31E11) Rabbit mAb (Cell Signaling, 4835s), EGLN3/PHD3 Antibody (Novus Biologicals ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling 4695, 1:2000), rabbit anti-phospho-PAK1 (S199/S204 ...
• SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

  Yen K. Lieu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-p-MAPKAPK-2 (MK2; T334) (Cell Signaling, 9595T), anti-α-Tubulin (Cell Signaling ...
• Zfp36l1 and Zfp36l2 balances proliferation and differentiation in the developing retina

  Fuguo Wu, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and rabbit anti-Zfp36l1/2 (Cell signaling 2119,1:100). Secondary antibodies were purchased from Life Sciences.
• Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)

  Honglin Jiang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Erk1/2 (Cell Signaling Technology, 4696, Dilution: 1:1000); GAPDH (Cell Signaling Technology ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... P-ERK1/2 Thr202/Tyr204 (Cell Signaling Technology #4370), 1:2000 ...
• Androgen Receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR

  Bosen You, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Argonaute-2 (Ago2) (Cell Signaling Technology, #2897, Danvers, MA), IgG (Santa Cruz ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal pSMAD 2/3 (Cell Signaling; 8828, Massachusetts, USA), monoclonal pSMAD 1/5/9 (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... MEK1/2 (Cell Signaling 1:1000, #9122, 1:1000), phospho-MEK1/2 S217/221 (Cell Signaling ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... SHP-1 or SHP-2 (all Cell Signaling Technology) followed by anti-rabbit Dylight649 (1:500 ...
• Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS dependent apoptosis in ovarian cancer cells by targeting PAR-1

  Niraj Nag, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti Bcl-2 antibody (Cell Signaling Technology Cat# 15071), anti-caspase 8 antibody (Cell Signaling Technology Cat# 9746) ...
• The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids

  Jennifer Rynne, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Antibodies used were: BRF1/2 (Cell Signaling Technology #2119), GR (Cell Signaling Technology #3660 ...
• Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

  Eleftheria Koropouli, et al., bioRxiv - Neuroscience 2022

  Quote: ... Neuropilin-2 (rabbit polyclonal, Cell Signaling, Cat no. 3366S); Neuropilin-2 (goat polyclonal ...
• PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties

  Tejashree Joglekar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling #4696); anti-KRAS (Sigma #WH0003845M1) ...
• Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment

  Gabriela Traczyk, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-flotillin-2 (Cell Signaling, cat. No. 3436), donkey anti-sheep IgG-HRP (Jackson ImmunoResearch ...
• Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

  Mingrong Zuo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-ERK1/2(Thr202/Tyr204) (Cell Signaling Technology #4370S), total-ERK1/2 (Cell Signaling Technology #4696) ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... ERK1/2 (1:1000, Cell Signaling Technology, Cat# 9102), phospho-p38 (Thr180/Tyr182 ...
• Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function

  Chao Chang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling Technology, #9102; RRID:AB_330744), goat polyclonal anti-EPHB2 (R&D Systems ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... ERK1/2 (1:1000; 9102; Cell Signaling Technology, Inc.); phospho-AKT (Ser473 ...
• Ellagic acid ameliorates atherosclerosis by targeting the epidermal growth factor receptor

  Ye-Wei Huang, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK1/2 (4696S, Cell Signaling Technology, MA, USA), anti-phospho-ERK1/2 (4370S ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ERK1/2 (Cell Signaling, USA, 1:1000 dilution), anti-p38 (Cell Signaling ...
• Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7

  Haley M. Scott, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 µg of isotype control (IgG, Cell Signaling), 5ul Y701 STAT1 (Cell Signaling) ...
• Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

  E. M. Poursani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p44/42 MAPK (ERK1/2) (9102S, Cell Signaling Technology), MMP-9 (D6O3H ...
• Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

  Abir Mukherjee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HK-2 (Cell Signaling Technology, cat# 2867, 1:1000), p-STAT3 Tyr 708 (Cell Signaling Technology ...
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho Myosin Light Chain 2 (Cell Signaling 3671) and secondary antibody anti-rabbit AlexaFluor 488 (Invitrogen A-21441) ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-ERK1/2 (1:200; 4370; Cell Signaling Technology), phospho-AKT (1:8,000 ...
• Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

  Baptiste Fischer, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit monoclonal ERK1/2 (1:50, Cell Signaling #4696), and mouse monoclonal Flag antibody (clone M2 ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Cox-2 (1:1,000, 9461, Cell Signaling Technology), anti-β-actin (1:2,000 ...
• Antagonistic pleiotropy plays an important role in governing the evolution and genetic diversity of SARS-CoV-2

  Ding-Chin Lee, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... rabbit anti-SARS-CoV-2 envelope (Cell signaling, #74698), rabbit anti-GAPDH (Genetex ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat.No.9102S, 1:1000), phospho-4EBP1 (Cell Signaling Technology ...
• Actin polymerization drives lumen formation in a human epiblast model

  Dhiraj Indana, et al., bioRxiv - Developmental Biology 2023

  Quote: ... phospho- myosin light chain 2 (Cell Signaling Technology #3674), Arp2/3 complex (Sigma-Aldrich MABT95) ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-MAPKAPK-2 (1:1000, Cell Signaling 3042), rabbit anti-phospho-MAPKAPK-2 (Thr222 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-MEK1/2 (1:1000; # 9122; Cell Signaling), rabbit anti-phospho-MEK1/2 (1:1000 ...
• Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

  Aurelien Chuard, et al., bioRxiv - Microbiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) Antibody (Cell Signaling #9102); β-Actin (D6A8 ...
• Braf-mutant Schwann cells divert to a repair phenotype to induce congenital demyelinating neuropathy

  Elise Marechal, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit polyclonal anti-Erk1/2 (#9102; Cell Signaling Technology), rabbit monoclonal anti-Jun (60A8 ...
• Synthetic G protein-coupled receptors for programmable sensing and control of cell behavior

  Nicholas A. Kalogriopoulos, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... p44/42 MAPK (Erk1/2; Cell Signaling Technology #9107), and β-Tubulin (Cell Signaling Technology #86298).
• Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO

  Kanpitcha Jiramitmongkon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Bcl–2 (1:1000; 25 – 28 kDa, Cell signaling), and Bax (1:1000 ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Membrane protein (Cell Signaling Technology, 15333S); SARS-CoV-2 Envelope protein (Cell Signaling Technology ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Envelope protein (Cell Signaling Technology, 74698S); furin (Proteintech ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... total MEK1/2 (1:1000, Cell Signaling Technology #9122), Cofilin (1:1000 ...
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  Erin Skeens, et al., bioRxiv - Biochemistry 2024

  Quote: ... and anti-phospho-ERK1/2 (Cell Signaling cat# 9101) antibodies ...
• Kinase Plasticity in Response to Vandetanib Enhances Sensitivity to Tamoxifen and Identifies Co-Treatment Strategies in Estrogen Receptor Positive Breast Cancer

  Rasha T. Kakati, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Cell Signaling Technologies), RET (Abcam) ...