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6401 - 6450 of 10000+ citations since 2019

• VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

  Virginie Menez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-Phalloidine (1/200 #8940S, Cell signaling) and 45 minutes with secondary antibodies (Alexa fluor ...
• PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

  Rafik Boudra, et al., bioRxiv - Cancer Biology 2023

  Quote: ... FRA1 (25μl, Cell Signaling Technology, 3753), JUNB (25μl ...
• Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2

  Julia Taylor, et al., bioRxiv - Immunology 2023

  Quote: ... GAPDH (Cell Signaling technology; 2118), Anti-Rabbit IgG HRP (Cell Signaling technology ...
• Increased response to immune checkpoint inhibitors with dietary methionine restriction

  Lauren C. Morehead, et al., bioRxiv - Cancer Biology 2023

  Quote: ... followed by incubation with rabbit anti-PD-L1 (64988, 1:100, Cell Signaling Technology), rat anti-CD8 (14-0808-80 ...
• XIAP-mediated targeting of endolysosomes to stressed mitochondria occurs in a switch-like, global manner and results in autophagy-independent, sub-organelle level mitochondrial degradation

  Tim Sen Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... Rab5 (Cell Signaling; no. 3547S), XIAP (Santa Cruz Biotechnology ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Amyloid-β (1:100; Cell Signaling, 8243), anti-Amyloid-β (1-42 ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H3K4me3 1:50 (Cell Signaling Technology, Cat 9751), H3K27me3 1:50 (Cell Signaling Technology ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ChIP-Seq libraries were prepared using the DNA Library Prep Kit for Illumina (Cell Signaling Technology, Cat 56795) and the Multiplex Oligos for Illumina (Dual Index Primers ...
• Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex

  Raghavendra Vadla, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-RelA/p65 (Cell Signaling Technology, #8242), anti-BRD4 (Cell Signaling Technology ...
• Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex

  Raghavendra Vadla, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-acetyl-NF-κB p65 (Cell Signaling Technology, #3045), anti-BRD3 (Santa Cruz Biotechnology ...
• Differential modulation of miR-122 transcription by TGFβ1/BMP6: implications for nonresolving inflammation and hepatocarcinogenesis

  Martha Paluschinski, et al., bioRxiv - Cancer Biology 2023

  Quote: ... the mouse specific Smad4 siRNA (Cat.12791; Cell Signaling) and the Signal Silence Control siRNA (Cat.6568S ...
• Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

  Yuhan Jiang, et al., bioRxiv - Biochemistry 2023

  Quote: ... or anti β-actin (Cell Signaling, Cat# 4970S) at 4°C overnight ...
• Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

  Yuhan Jiang, et al., bioRxiv - Biochemistry 2023

  Quote: ... which were detected with HRP-conjugated goat anti-rat immunoglobulin-G at 1:5000 dilution (Cell Signaling Technology, Cat# 7077S) or goat anti-rabbit immunoglobulin-G at 1:3000 dilution (Cell Signaling Technology ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p-p44/42 MAPK (pERK1/2) (Cell Signaling Technology, 9101S, 1:1,000) and β-actin (Cell Signaling Technology ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and β-actin (Cell Signaling Technology, 3700S, 1:5,000).
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Phospho-Akt (Cell Signaling Technology, 4060S), p44/42 MAPK (ERK1/2 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 4695S, 1:1,000), p-p44/42 MAPK (pERK1/2 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... AKT antibody (Cell Signaling Technology, 9272S), Phospho-Akt (Cell Signaling Technology ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ki67 (Cell Signaling Technology, 11882S, 1:1000), AKT antibody (Cell Signaling Technology ...
• The chromatin landscape of healthy and injured cell types in the human kidney

  Debora L. Gisch, et al., bioRxiv - Molecular Biology 2023

  Quote: ... H3K27me3 (Cell Signaling, 9733), H3K4me1 (Cell Signaling ...
• THUMPD2 catalyzes N²-methylation on the spliceosome catalytic center of U6 snRNA and regulates pre-mRNA splicing

  Wen-Qing Yang, et al., bioRxiv - Biochemistry 2023

  Quote: ... the fixed cells were blocked in PBS containing 5% bovine serum albumin (BSA) and then incubated with mouse anti-HA antibody (6E2, Cell signaling Technology) with 1:800 dilution overnight at 4°C ...
• APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

  Michael S. Haney, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Caspase-3 (9661, Cell Signaling Technology, 1:500). The secondary antibodies were IgG conjugated to Alexa Fluor 488 (donkey anti-mouse ...
• HOMOCYSTEINE POTENTIATES AMYLOID β-INDUCED CEREBRAL ENDOTHELIAL CELL APOPTOSIS, BLOOD BRAIN BARRIER DYSFUNCTION AND ANGIOGENIC IMPAIRMENT

  Ashley Carey, et al., bioRxiv - Neuroscience 2023

  Quote: ... or anti-GAPDH (Cell signaling; 32233). Proteins were electrotransferred to nitrocellulose membranes (0.45 μm pore size ...
• Inducible genetic ablation of Immt induces a lethal disruption of the MICOS complex

  Stephanie M. Rockfield, et al., bioRxiv - Physiology 2023

  Quote: ... and GAPDH (Cell Signaling Technologies). Chemiluminescence was read on a Li-COR Odyssey Fc Imager (Li-COR Biosciences ...
• A Medium Chain Fatty Acid, 6-hydroxyhexanoic acid (6-HHA), Protects Against Obesity and Insulin Resistance

  Sara C. Sebag, et al., bioRxiv - Physiology 2023

  Quote: ... at 1:1000 and then incubated with the appropriate secondary antibody conjugated with horseradish peroxidase (1:5000, Santa Cruz, sc-2005 or 1:5000, Cell Signaling Technology, 7074S). Signal was detected using the ChemiDoc Touch Imaging System (Bio-Rad) ...
• A Medium Chain Fatty Acid, 6-hydroxyhexanoic acid (6-HHA), Protects Against Obesity and Insulin Resistance

  Sara C. Sebag, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were incubated with anti-p-AKT (Ser473, Cell Signaling, 9271); anti-AKT1 (H-136 ...
• Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype

  Emily A. Davidson, et al., bioRxiv - Physiology 2023

  Quote: ... The secondary antibody (HRP-conjugated goat anti-rabbit) (Cell Signaling Technology #7074, Danvers, MA) was used at a dilution of 1:1000 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... Pan-Akt (1:1000, Cell Signaling), pAkt (S437 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... AMPK (1:1000, Cell Signaling), pAMPK (1:1000 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... pAMPK (1:1000, Cell Signaling), Vinculin ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... pAkt (S437) (1:1000, Cell Signaling), AMPK (1:1000 ...
• Beclin1-Deficient Adipocytes Promote Tumor Progression by YAP/TAZ-dependent Adipocyte Transformation

  Yaechan Song, et al., bioRxiv - Biochemistry 2023

  Quote: ... 12hosphor-YAP (#13008; Cell Signaling Technology), Lipocalin2 (LCN2 ...
• A comprehensive atlas of the aging vertebrate brain reveals signatures of progressive proteostasis dysfunction

  Domenico Di Fraia, et al., bioRxiv - Systems Biology 2023

  Quote: Killifish brains and cells treated for 24 hours with anisomycin (Cell Signaling Technology, 2222) were lysed following as described in “Sample preparation for total proteome and analysis of PTMs” ...
• Beclin1-Deficient Adipocytes Promote Tumor Progression by YAP/TAZ-dependent Adipocyte Transformation

  Yaechan Song, et al., bioRxiv - Biochemistry 2023

  Quote: ... and phosphor-HSL (#4137, #4139, #45804; Cell Signaling Technology).
• Beclin1-Deficient Adipocytes Promote Tumor Progression by YAP/TAZ-dependent Adipocyte Transformation

  Yaechan Song, et al., bioRxiv - Biochemistry 2023

  Quote: ... HSL (#4107; Cell Signaling Technology), and phosphor-HSL (#4137 ...
• Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations

  Alex Hanson, et al., bioRxiv - Physiology 2023

  Quote: ... rabbit anti-α-SMA (1:100; D4K9N, XP; Cell Signaling Technology), and rabbit anti-TAGLN (1:100 ...
• 17α-estradiol Alleviates High-Fat Diet-Induced Inflammatory and Metabolic Dysfunction in Skeletal Muscle of Male and Female Mice

  Matthew P. Bubak, et al., bioRxiv - Physiology 2023

  Quote: ... and 4E-BP1 (1:50, #9452, Cell Signaling, Danvers, MA). Secondary antibodies were included in a WES Master Kit (DM-001 ...
• Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen

  Hong Nhung Vu, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Anti-β-Actin (Cell Signaling, #4970) at 1:1000 dilution ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ubiquitin (43124S, Cell Signaling Technology, rabbit, 1:1000); Ubiquitin (sc-8017 ...
• Interaction of PINK1 with nucleotides and kinetin

  Zhong Yan Gan, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-phospho-ubiquitin (Ser65) E2J6T (1:1,000, Cell Signaling Technology, 62802), rabbit anti-Tom20 FL-145 (1:1,000 ...
• Interaction of PINK1 with nucleotides and kinetin

  Zhong Yan Gan, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Primary antibodies used were rabbit anti-PINK1 D8G3 (1:1,000, Cell Signaling Technology, 6946), rabbit anti-phospho-ubiquitin (Ser65 ...
• A new pipeline SPICE identifies novel JUN-IKZF1 composite elements

  Peng Li, et al., bioRxiv - Systems Biology 2023

  Quote: ... the nuclear extract was pre-incubated for 20 minutes on ice with anti-cJUN rabbit mAb (clone 60A8) from Cell Signaling technologies (#9165S) or with anti-IKZF1 (clone IK14) ...
• GSK3 inhibition improves skeletal muscle function and whole-body metabolism in the severe DBA/2J mdx mouse model

  Bianca M. Marcella, et al., bioRxiv - Physiology 2023

  Quote: ... both from development studies hybridoma bank) and corresponding anti-mouse horseradish peroxidase secondary antibody (7076, Cell Signaling) prior to imaging with a BioRad ChemiDoc Imager with Immobilon ECL Ultra Western HRP Substrate (WBKLS0500 ...
• Outer mitochondrial membrane E3 Ub ligase MARCH5 controls mitochondrial steps in peroxisome biogenesis

  Nicolas Verhoeven, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by horseradish peroxidase-conjugated anti-mouse (Cell Signaling) or anti-rabbit (Cell Signaling ...
• Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression

  Dipon K. Mondal, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (1:4000, #2118), Phospho-Akt (Ser473) (1:500, #9271) and Akt antibody (1:1000, #9272) were obtained from Cell Signaling Technology (Beverly, MA). Human VEGFR3/Flt-4 antibody (1:500 ...
• Mechano-induced homotypic patterned domain formation by monocytes

  Wenxuan Du, et al., bioRxiv - Biophysics 2023

  Quote: ... All the antibodies were purchased from Cell Signaling Technology.
• Impact of Microscopic Quantum Mechanisms on Macroscopic Epigenetic Regulation through Histone Deacetylation

  Takeshi Yasuda, et al., bioRxiv - Biophysics 2023

  Quote: ... and anti-GAPDH (2118, Cell Signaling).
• Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

  Ali Rashidfarrokhi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... RRID: AB_2335990) and rabbit anti-human pSTAT3 clone D3A7 (Cell Signaling Technologies Cat# 9145, Lot# 43 RRID: AB_2491009) raised against a synthetic phosphopeptide corresponding to residues surrounding Tyrosine 705 of murine STAT3 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Rubicon (1:1000, #8465, Cell Signaling Technology), anti-EGFR (1:100 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-ATG9A (1:1000, #13509, Cell Signaling Technology), anti-Rubicon (1:1000 ...