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5551 - 5600 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Pharmacologic activation of the G protein-coupled estrogen receptor inhibits pancreatic ductal adenocarcinoma

  Christopher A. Natale, et al., bioRxiv - Cancer Biology 2019

  Quote: ... and RB (Cell Signaling Technology, #9313, 1:1000). After incubation with the appropriate secondary antibody ...
• Intestinal-epithelial LSD1 controls cytoskeletal-mediated cell identity including goblet cell effector responses required for gut inflammatory and infectious diseases

  Naveen Parmar, et al., bioRxiv - Immunology 2020

  Quote: ... Phospho-Stat3 (1:100, Cell Signaling Technology, 9145), STAT3 (1:1600 ...
• Non-apoptotic caspase activity sustains proliferation and differentiation of ovarian somatic cells by modulating Hedgehog-signalling and autophagy

  Alessia Galasso, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-HA (1:1000; Cell Signaling C29F4); mouse anti-β-Gal (1:500 ...
• A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells

  Kushani Shah, Gwendalyn D King, Hao Jiang, bioRxiv - Developmental Biology 2019

  Quote: ... Gfap (1:500, Cell Signaling, Danvers, MA, 3670S), NeuN (1:300 ...
• Microtubules coordinate protrusion-retraction dynamics in migrating dendritic cells

  Aglaja Kopf, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti ERM (1:500, all Cell Signaling), mouse anti glyceraldehyde 3-phosphate dehydrogenase (GAPDH ...
• Sex-specific Alterations in Hepatic Cholesterol Metabolism in Young Uteroplacental Insufficiency-induced Low Birth Weight Adult Guinea Pig Offspring

  Ousseynou Sarr, et al., bioRxiv - Physiology 2020

  Quote: ... anti-mouse (7076S; 1:5000, Cell Signaling Technology). Membranes were developed using the Clarity or Clarity Max ECL substrate (BioRad) ...
• Abundance and localization of human UBE3A protein isoforms

  Carissa L. Sirois, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-BAK (1:1000; Cell Signaling Technologies). The following secondary antibodies were used at a concentration of 1:10000 ...
• Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism

  Chew Leng Lim, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and perilipin A (1:100, D418 Cell Signaling) or cleaved caspase 3 (1:100 ...
• LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is altered in Townes-Brocks Syndrome

  Laura Bozal-Basterra, et al., bioRxiv - Cell Biology 2019

  Quote: ... HRP-conjugated anti-biotin (Cell Signaling, 1:2,000), anti Myc (Cell Signaling ...
• ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming

  Fei Li, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HA (Cell Signaling Technology, cat# 3724, 1:200); Ki67 (Abcam ...
• AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

  Kunihiko Yamashiro, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit-GAPDH (1:1000, 2118S, Cell Signaling Technology), and then visualized using HRP-conjugated secondary antibody (GE Healthcare ...
• AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

  Kunihiko Yamashiro, et al., bioRxiv - Neuroscience 2020

  Quote: ... Rabbit-Mef2c (1:500, D80C1, Cell Signaling Technology), guinea pig-CaV2.1 (1:200 ...
• Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus

  Gonca Bayraktar, et al., bioRxiv - Neuroscience 2019

  Quote: ... myc-tag (1:1000, Cell Signaling, catalog #2276), and horseradish peroxidase-coupled goat anti mouse/rabbit IgG-HRP linked secondary antibodies (1:20000 ...
• BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

  Drake Edwards, et al., bioRxiv - Cancer Biology 2020

  Quote: ... c-Myc (1:1000WB, 5605S, Cell Signaling Technology); Cleaved Caspase 3 (1:500WB ...
• BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

  Drake Edwards, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved PARP (1:1000WB, 5625, Cell Signaling Technology); BrdU (1:20IF ...
• Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

  Ying Ann Chiao, et al., bioRxiv - Physiology 2020

  Quote: ... Troponin I (Cell Signaling Technology #4002, 1:1000), pSer23/24-Troponin I (Cell Signaling Technology #4004 ...
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 mM β-glycerol-phosphate] (Cell Signaling Technology). Samples were frozen in dry ice/ethanol and then analyzed using the PTMScan method (Cell Signaling Technology ...
• Antagonistic roles of NOT1 paralogues in the timing of gene expression in Plasmodium falciparum

  Ying Liu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and 1:2,000 anti-mouse antibody (Cell Signaling). Aldolase as a cytoplasmic marker was detected by 1:2,000 anti-aldolase antibody (Abcam ...
• De novo protein synthesis in distinct centrolateral amygdala interneurons is required for associative emotional memories

  Prerana Shrestha, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-S6 1:500 (Cell Signaling #2317), rabbit anti-p-S6K1 Thr389 1:500 (Cell Signaling #9205) ...
• De novo protein synthesis in distinct centrolateral amygdala interneurons is required for associative emotional memories

  Prerana Shrestha, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-S6K1 1:500 (Cell Signaling #2708), rabbit anti-p eIF2α Ser51 1:300 (Cell Signaling #9721) ...
• YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

  Sylvain Lefort, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-H3 (Cell Signaling Technology, 12648, 1/10,000), anti-RAS (Cell Signaling Technologies ...
• Hox-dependent coordination of cardiac progenitor cell patterning and differentiation

  Sonia Stefanovic, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Rabbit anti-Caspase3 (Cell Signaling Technology, 1/300), rabbit anti-phospho-Histone H3 (Merck ...
• A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

  Jason W. Millington, et al., bioRxiv - Physiology 2021

  Quote: ... and 1:3000 for actin (#7076; Cell Signaling). Membranes were washed (3 x 2 min ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-CTSD (1:1000, Cell Signaling Technology), mouse anti-PDI (1:2000 ...
• YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

  Sylvain Lefort, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-RAS (Cell Signaling Technologies, 3339, 1/1,000), anti-YB-1 (Cell Signaling Technology ...
• Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

  Evelyn L. Eastwood, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-HA (1:2,500; Cell Signaling Technology C29F4) anti-Tubulin (1:2,500 ...
• Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

  Evelyn L. Eastwood, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-FLAG (1:1,000; Cell Signaling Technology 14793S) and anti-Lamin (1:200 ...
• Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

  Delphine M. Lees, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PDGFRβ (Cell Signaling, clone 28E10, 3169, 1:1000), endomucin (V7.C7 ...
• Paxillin Promotes ATP-induced Activation of P2X7 Receptor and NLRP3 Inflammasome

  Wenbiao Wang, et al., bioRxiv - Immunology 2020

  Quote: ... mature IL-1β (Asp116 1:500, Cell Signaling), polyclonal rabbit anti-caspase-1 p10 (sc-515 ...
• Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

  Erika Liktor-Busa, et al., bioRxiv - Neuroscience 2019

  Quote: ... and α-tubulin (Cell Signaling, 3873S, 1:20,000). The membranes were incubated in the diluted primary antibodies overnight at 4°C ...
• Alzheimer’s disease-related dysregulation of protein synthesis causes key pathological features with ageing

  Anshua Ghosh, et al., bioRxiv - Neuroscience 2019

  Quote: ... phospho-eIF4E Ser209 (Cell Signaling 9741 1:1000), eIF4E (Cell Signaling 2067 ...
• The conserved Drosophila SWI/SNF chromatin-remodeling complexes BAP and PBAP play separate roles in regulating growth and cell fate during regeneration

  Yuan Tian, Rachel K. Smith-Bolton, bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-phospho-Mad (1:100; Cell Signaling), mouse anti-Mmp1 (1:10 of 1:1:1 mixture of monoclonal antibodies 3B8D12 ...
• Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements

  Tianfang Yang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-GAPDH (2118S; Cell Signaling Technology; 1:2000). The secondary antibody used was ...
• Exploiting codon usage identifies RpS21 as an in vivo signal strength-dependent Ras/MAPK regulator

  Jessica K. Sawyer, et al., bioRxiv - Genetics 2019

  Quote: ... anti-p- ERK1/2 (Cell Signaling, 1:1000), anti-ERK1/2 (Cell Signaling ...
• Exploiting codon usage identifies RpS21 as an in vivo signal strength-dependent Ras/MAPK regulator

  Jessica K. Sawyer, et al., bioRxiv - Genetics 2019

  Quote: ... anti-p-MEK1/2 (Cell Signaling, 1:500), anti-MEK1/2 (Cell Signaling ...
• Microbiota–modulated enteric neuron translational profiling uncovers a CART+ glucoregulatory subset

  Paul A Muller, et al., bioRxiv - Neuroscience 2020

  Quote: ... pCREB Ser133 (1:200, Cell Signaling Technologies, 9198S), ANNA-1 (1:200,000 ...
• AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia

  Luting Poh, et al., bioRxiv - Neuroscience 2020

  Quote: ... IBA-1 (Wako, 016-26721; Cell Signaling, #17198), CD86 (Santa Cruz ...
• AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia

  Luting Poh, et al., bioRxiv - Neuroscience 2020

  Quote: ... Cleaved Caspase-1 (p20 subunit) (Cell Signaling, #67314), Casapse-8 (Cell Signaling ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-Vinculin (#4650, 1:1000 dilution, Cell Signaling). Following the incubation with a primary antibody ...
• Development of conformational BRET biosensors that monitor Ezrin, Radixin and Moesin activation in real-time

  Kévin Leguay, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Moesin (1:1000, Cell Signaling #3150), rabbit anti-phospho-ERM (1:5000,10) ...
• Development of conformational BRET biosensors that monitor Ezrin, Radixin and Moesin activation in real-time

  Kévin Leguay, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Radixin (1:1000, Cell Signaling #2636), rabbit anti-Moesin (1:1000 ...
• Development of conformational BRET biosensors that monitor Ezrin, Radixin and Moesin activation in real-time

  Kévin Leguay, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Ezrin (1:1000, Cell Signaling #3145), rabbit anti-Radixin (1:1000 ...
• Pharmacologically modified pluripotent stem cell-based cancer vaccines with anti-metastatic potential

  Masae Heront-Kishi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and α-Nanog (Cell Signaling, dilution 1:100) and the secondary antibodies goat anti-mouse Cy3 (Abcam ...
• Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis

  Rachel M. Stewart, et al., bioRxiv - Cell Biology 2019

  Quote: ... S6 (1:5000, rabbit, Cell Signaling 2217 clone5G10), pS6 (1:5000 ...
• Melanoma plasticity is controlled by a TRIM28-JUNB mediated switch

  William A Nyberg, et al., bioRxiv - Cancer Biology 2019

  Quote: ... 1 μg anti-JUNB (#3753, Cell Signaling Technologies) or 1 μg isotype control antibody (#3900 ...
• Modeling motor neuron resilience in ALS using stem cells

  Ilary Allodi, et al., bioRxiv - Neuroscience 2019

  Quote: ... phospho-AKT (Ser473) (1:50, #3787 Cell Signaling), activated beta-catenin (1:1000 ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-GAPDH (1/2000, Cell Signaling, #2118), rabbit anti-EB1 (1/2500 ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-GSK3β (1/1000, Cell Signaling, #12456), rabbit anti-ser473 phospho Akt (1/1000 ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-Akt (1/1000, Cell Signaling, #9272), rabbit anti-ser16 phospho Op18 (1/500 ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Phospho-MLKL (Ser345) (1:1000, #62233, Cell signaling); MLKL (1:1000 ...