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5801 - 5850 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... HSL-pS660 (1:1000, Cell signaling, Cat#4126), HSL-pS563 (1:1000 ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... AKT-pS473 (1:1000; Cell signaling, Cat#9271), CALNEXIN (1:1000 ...
• Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

  Irina C Frei, et al., bioRxiv - Physiology 2022

  Quote: ... HSL-pS563 (1:1000, Cell signaling, Cat#4139). The primary antibody was washed several times with TBST and then incubated in secondary antibody in TBST containing 5% milk powder (w/v) ...
• Semaphorin3F reduces vascular endothelial and smooth muscle cell PI3K activation and decreases neointimal plaque formation

  Chutima Rattanasopa, et al., bioRxiv - Physiology 2022

  Quote: ... anti-VE-cadherin (1:200; 2158; Cell Signaling). To visualize F-Actin and nuclei ...
• A pathogenicity locus of Streptococcus gallolyticus subspecies gallolyticus

  John Culver Taylor, Ritesh Kumar, Juan Xu, Yi Xu, bioRxiv - Microbiology 2022

  Quote: ... and β-actin (1:1000) (Cell Signaling Technology), followed by incubation with HRP-conjugated secondary antibodies (1:3000) ...
• The pore-forming protein gasdermin D is a cellular redox sensor

  Pascal Devant, et al., bioRxiv - Immunology 2022

  Quote: ... rabbit monoclonal anti-RagA (Cell Signaling, 1:1000), rabbit monoclonal anti-caspase-8 (Cell Signaling ...
• The pore-forming protein gasdermin D is a cellular redox sensor

  Pascal Devant, et al., bioRxiv - Immunology 2022

  Quote: ... rabbit monoclonal anti-RIPK1 (Cell signaling, 1:1000), rabbit polyclonal anti-tagRFP (Evrogen ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... p-Akt (1:2000, #4060; Cell Signaling Technology), and Akt (1:2000 ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... and Akt (1:2000; #4691; Cell Signaling Technology) were used for the immunohistochemical staining ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Exportin 5 (1:1000) (Cell Signaling #12565), anti-β-actin (1:5000 ...
• POGZ suppresses 2C transcriptional program and retrotransposable elements

  XY Sun, TZ Zhang, LX Cheng, W Jiang, YH Sun, bioRxiv - Molecular Biology 2022

  Quote: ... anti-H4K20me3 (Cell Signaling Technology, 5737s, 1: 1000), anti-SETDB1 (Proteintech ...
• Fibronectin-integrin α5 signaling promotes thoracic aortic aneurysm in a mouse model of Marfan syndrome

  Minghao Chen, et al., bioRxiv - Pathology 2022

  Quote: ... and total-p65 (1:500, 4764s, Cell Signaling), and a dye ...
• Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging

  Emin Onur Karakaslar, et al., bioRxiv - Systems Biology 2022

  Quote: ... Lamin B1 (12586S, 1:100, Cell Signaling Technology), c-Jun (9165S ...
• Single cell transcriptomics of human skin equivalent organoids

  Adam R. Stabell, et al., bioRxiv - Systems Biology 2022

  Quote: ... rabbit anti-KRT19 (1:250; Cell signaling; 13092), mouse anti-KRT15 (1:500 ...
• Cell-type-specific whole-genome landscape of ΔFOSB binding in nucleus accumbens after chronic cocaine exposure

  Szu-Ying Yeh, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-FOSB (2251, Cell Signaling; 1:500 dilution), goat anti-rabbit antibody conjugated with HRP (G21234 ...
• Cell-type-specific whole-genome landscape of ΔFOSB binding in nucleus accumbens after chronic cocaine exposure

  Szu-Ying Yeh, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-H3K27me3 (9733, Cell Signaling, 1:50 dilution), anti-BRG1 (13-2002 ...
• The RSK-RPS6 Axis Controls the Preconditioning Effect and Induces Spinal Cord Regeneration

  Charlotte Decourt, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-RSK (1/500, RSK123-Cell signaling Technology) for 2h at room temperature and secondary antibodies ...
• Triptolide ameliorates renal tubulointerstitial fibrosis through EZH2

  Yanzhe Wang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-EZH2 (1:1000, 5246S, Cell Signaling Technology) antibody ...
• The viral packaging motor potentiates late gene expression in Kaposi’s sarcoma-associated herpesvirus

  Chloe O. McCollum, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-PABPC1 (1:1,000; Cell Signaling Technologies), rabbit anti-ORF6 (1:10,000) ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-AKT (Cell Signaling Technology, 2920, 1:1000) and anti-phospho-AKT Ser473 (Cell Signaling Technology ...
• A newly-recognized population of residual neural crest cells in the adult leptomeninges is re-activated for vascular repair

  Yoshihiko Nakamura, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pAkt antibody (1:50, 9271S, Cell Signaling), anti-pGSK3β antibody (1:50 ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-AKT (1:8,000; 4060; Cell Signaling Technology, phospho-S6 (1:1,000 ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-MET (1:150; 3077; Cell Signaling Technology), MET (1:100 ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-4EBP1 (1:100; 2855; Cell Signaling Technology), 4EBP1 (1:1,200 ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... PSD95 (1:1,000) (Cell Signaling, Cat. no. 3409), ULK1 (1:500 ...
• ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS

  Andrea Magrì, et al., bioRxiv - Neuroscience 2023

  Quote: ... Atg12 (Cell Signaling, ref. no. 4180, 1:1000), β-Actin (Cell Signaling ...
• ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS

  Andrea Magrì, et al., bioRxiv - Neuroscience 2023

  Quote: ... β-Actin (Cell Signaling, ref. no. 3700, 1:2000). Then ...
• Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response

  Yanan Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-T-eIF2α (Cell Signaling, 9722s, 1:1000), anti-puromycin (Millipore ...
• Innexin-mediated adhesion between glia is required for axon ensheathment in the peripheral nervous system

  Mriga Das, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Dcp1 (1:1000, Cell Signaling Technology). The following secondary antibodies were used at a 1:300 dilution ...
• Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cord

  Yuka Nakamura, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Sox9 (1:500; 82630S, Cell signaling), and rabbit ankyrin-G (1:500 ...
• Activity-dependent post-translational regulation of palmitoylating and de-palmitoylating enzymes in the hippocampus

  Danya Abazari, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-myc (1:1000, Cell Signaling Technology 2276), anti-GFP (1:3000 ...
• Activity-dependent post-translational regulation of palmitoylating and de-palmitoylating enzymes in the hippocampus

  Danya Abazari, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-HA (1:1000, Cell Signaling Technology C29F4), anti-myc (1:1000 ...
• Repetitive mild traumatic brain injury impairs resting state fMRI connectivity and alters protein profile signaling networks

  Sakthivel Ravi, et al., bioRxiv - Neuroscience 2022

  Quote: ... and GFAP (GA5) (1:1000, CS3670S, Cell Signaling) at 4°C for microglia and astrocytes ...
• Obesity Disrupts Pituitary UPR Leading to NAFLD

  Qingwen Qian, et al., bioRxiv - Physiology 2022

  Quote: ... CHOP (Cell Signaling, Cat No. 2895, 1:300) and PERK (Cell Signaling ...
• History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2022

  Quote: ... and total p42-MAPK (1:1000, Cell Signaling) which recognize both the p44- and p42-MAPK epitopes ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PP1 pT320 (1:1,000; Cell Signaling Technology), anti-PP1 (1:1,000 ...
• Unexpected proteinopathies in hippocampal PDE11A4 promote age-related cognitive decline of social associative memories

  K Pilarzyk, et al., bioRxiv - Neuroscience 2022

  Quote: ... NF-L (Cell Signaling #2837 at 1:10,000), β-tubulin (Covance PRB-435P at 1:100,000) ...
• Unexpected proteinopathies in hippocampal PDE11A4 promote age-related cognitive decline of social associative memories

  K Pilarzyk, et al., bioRxiv - Neuroscience 2022

  Quote: ... and GFAP (Cell Signaling 12389P at 1:10,000). The following day ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Smarcc2 (1:2000; Cell Signaling Technology, 12760), anti-Smarce1 (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Smarcc1 (1:2000; Cell Signaling Technology, 11956), anti-Smarcc2 (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Arid1a (1:2000; Cell Signaling Technology, 12354), anti-Arid1b (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Smarce1 (1:2000; Cell Signaling Technology, 33360), anti-Brd9 (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Arid1b (1:2000; Cell Signaling Technology, 92964), anti-Arid3b (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Suz12 (1:2000; Cell Signaling Technology, 3737), anti-HDAC1 (1:2000 ...
• Disruption of Smarce1, a component of the SWI/SNF chromatin remodeling complex, decreases nucleosome stability in mouse embryonic stem cells and impairs differentiation

  Katsunobu Kashiwagi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Ezh2 (1:2000; Cell Signaling Technology, 5246), anti-Suz12 (1:2000 ...
• The 2’,3’ cyclic phosphatase Angel1 facilitates mRNA degradation during human ribosome-associated quality control

  Tim Nicholson-Shaw, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-eIF4E (Cell Signaling Technologies 9742; 1:1,000), anti-SKIV2L (Thermo Fisher 11462-1-AP ...
• Enteroendocrine cell lineages that differentially control feeding and gut motility

  Marito Hayashi, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti-CRE (Cell Signaling 15036, 1:500), Rabbit anti-GLP1 (Novus 2622B MAB10473 ...
• Distinct modes of heat shock transcription factor interactions with mitotic chromosomes

  Rachel M. Price, et al., bioRxiv - Molecular Biology 2022

  Quote: ... α-H3K27me3 1:7000 (Cell Signaling Technologies, C36B11), α-Tubulin 1:7000 (Abcam ...
• The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation and Improves Autism-like Behavior in Zebrafish

  Golam M. Uddin, et al., bioRxiv - Molecular Biology 2022

  Quote: ... MFN1 (Cat# 3455S, Cell Signaling, USA; 1:1000); MFN2 (Cat# M03 ...
• Vitamin C is an efficient natural product for prevention of SARS-CoV-2 infection by targeting ACE2 in both cell and in vivo mouse models

  Yibo Zuo, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-STAT1 (Cell Signaling Technology, 9172, 1:1000), anti-Ubiquitin (Ub ...