Labshake Marketplace

351 - 400 of 1099 3 Chloro 3' 1 3 dioxolan 2 yl benzophenone from Selleck Chemicals

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  Tenovin-1

  Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and...

  Cat# S8000, SKU# S8000-10mg, 10mg, $70.00 Ask
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  MZ-1

  MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd...

  Cat# S8889, SKU# S8889-2mg, 2mg, $109.00 Ask
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  M2I-1

  M2I-1 is an inhibitor of Mad2 (mitotic arrest deficient 2) targeting the binding of Mad2 to...

  Cat# S0187, SKU# S0187-25mg, 25mg, $1289.00 Ask
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  Liproxstatin-1

  Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

  Cat# S7699, SKU# S7699-1g, 1g, $1970.00 Ask

  Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

  Johnson Ung, et al., bioRxiv - Cancer Biology 2023

  Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...
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  1-Methylnaphthalene

  1-Methylnaphthalene is an organic compound.

  Cat# S6277, SKU# S6277-25ul, 25ul, $97.00 Ask
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  4EGI-1

  4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM....

  Cat# S7369, SKU# S7369-10mg, 10mg, $197.00 Ask

  Cited in: Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

  Susanta Chatterjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...
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  ITD-1

  ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

  Cat# S6713, SKU# S6713-5mg, 5mg, $97.00 Ask
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  G-1

  G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30,...

  Cat# S0851, SKU# S0851-1mg, 1mg, $127.00 Ask
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  Spautin-1

  Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

  Cat# S7888, SKU# S7888-10mM/1mL, 10mM/1mL, $117.00 Ask
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  HCH6-1

  HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has...

  Cat# S0547, SKU# S0547-25mg, 25mg, $557.00 Ask
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  AMI-1

  AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

  Cat# S7884, SKU# S7884-5mg, 5mg, $97.00 Ask
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  OF-1

  OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively.

  Cat# S7681, SKU# S7681-25mg, 25mg, $347.00 Ask
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  BMS-1

  BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

  Cat# S7911, SKU# S7911-5mg, 5mg, $147.00 Ask
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  ITD-1

  ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

  Cat# S6713, SKU# S6713-25mg, 25mg, $297.00 Ask
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  Liproxstatin-1

  Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

  Cat# S7699, SKU# S7699-25mg, 25mg, $477.00 Ask

  Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

  Johnson Ung, et al., bioRxiv - Cancer Biology 2023

  Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...
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  RI-1

  RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.

  Cat# S8077, SKU# S8077-10mM/1mL, 10mM/1mL, $217.00 Ask
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  OSMI-1

  OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 μM for full...

  Cat# S9835, SKU# S9835-25mg, 25mg, $390.00 Ask
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  TAPI-1

  TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also...

  Cat# S7434, SKU# S7434-5mg, 5mg, $945.00 Ask

  Cited in: Targeting neuronal activity-regulated neuroligin-3 dependency for high-grade glioma therapy

  Humsa S. Venkatesh, et al., bioRxiv - Neuroscience 2017

  Quote: ... TAPI-1 at 20uM (ADAM17 inhibitor; S7434; Selleck Chemicals); GI 254023X at 200nM (ADAM10 inhibitor ...
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  Sephin-1

  Sephin-1 (NSC-65390) is a selective inhibitor of a holophosphatase, a small molecule that safely...

  Cat# S6391, SKU# S6391-5mg, 5mg, $127.00 Ask
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  TPI-1

  TPI-1 (Tyrosine Phosphatase Inhibitor 1) is a potent inhibitor of SHP-1 with IC50 of 40 nM for...

  Cat# S6570, SKU# S6570-25mg, 25mg, $497.00 Ask
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  HA14-1

  HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.

  Cat# S1071, SKU# S1071-10mg, 10mg, $79.00 Ask
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  NQDI-1

  NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic...

  Cat# S8289, SKU# S8289-10mg, 10mg, $97.00 Ask
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  1-Hexadecanol

  1-Hexadecanol is a fatty alcohol used to make other chemicals.

  Cat# S4173, SKU# S4173-50mg, 50mg, $97.00 Ask
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  1-Furfurylpyrrole

  1-Furfurylpyrrole (N-Furfurylpyrrole) is a potential contributor of flavor and aroma to popcorn.

  Cat# S6107, SKU# S6107-25ul, 25ul, $97.00 Ask
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  HOIPIN-1

  HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC)...

  Cat# S6396, SKU# S6396-25mg, 25mg, $657.00 Ask
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  PAC-1

  PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known...

  Cat# S2738, SKU# S2738-10mM/1mL, 10mM/1mL, $120.00 Ask
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  BTB-1

  BTB-1 is a novel, selective and reversible inhibitor of the mitotic motor protein Kif18A with...

  Cat# S6796, SKU# S6796-25mg, 25mg, $177.00 Ask
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  A2ti-1

  A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)...

  Cat# E1421, SKU# E1421-25mg, 25mg, $890.00 Ask
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  BH3I-1

  BH3I-1 is a Bcl-XL-BH3 domain interaction inhibitor with Ki of 2.4 μM (by fluorescence...

  Cat# S8177, SKU# S8177-5mg, 5mg, $97.00 Ask
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  Leukadherin-1

  Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion...

  Cat# S8306, SKU# S8306-10mg, 10mg, $97.00 Ask
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  TRi-1

  TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic...

  Cat# S0267, SKU# S0267-5mg, 5mg, $187.00 Ask
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  NGI-1

  NGI-1 is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase...

  Cat# S8750, SKU# S8750-10mg, 10mg, $97.00 Ask
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  TAI-1

  TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.

  Cat# S7495, SKU# S7495-25mg, 25mg, $477.00 Ask
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  Mdivi-1

  Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of...

  Cat# S7162, SKU# S7162-20mg, 20mg, $147.00 Ask
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  BTZO-1

  BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats...

  Cat# S0539, SKU# S0539-25mg, 25mg, $417.00 Ask
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  Alda 1

  Alda 1 is an ALDH2 agonist that activates catalysis for both wild-type ALDH2 (ALDH2*1) and ALDH2*2.

  Cat# S5800, SKU# S5800-25mg, 25mg, $290.00 Ask
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  TAPI-1

  TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also...

  Cat# S7434, SKU# S7434-10mM/1mL, 10mM/1mL, $1190.00 Ask

  Cited in: Targeting neuronal activity-regulated neuroligin-3 dependency for high-grade glioma therapy

  Humsa S. Venkatesh, et al., bioRxiv - Neuroscience 2017

  Quote: ... TAPI-1 at 20uM (ADAM17 inhibitor; S7434; Selleck Chemicals); GI 254023X at 200nM (ADAM10 inhibitor ...
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  Oncrasin-1

  Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills...

  Cat# S0780, SKU# S0780-25mg, 25mg, $297.00 Ask
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  BLT-1

  BLT-1(Block lipid transport-1), a thiosemicarbazone copper chelator, is a selective inhibitor of...

  Cat# S0857, SKU# S0857-25mg, 25mg, $687.00 Ask
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  Shield-1

  Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12...

  Cat# S3469, SKU# S3469-25mg, 25mg, $1470.00 Ask
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  G-1

  G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30,...

  Cat# S0851, SKU# S0851-10mM/1mL, 10mM/1mL, $439.00 Ask
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  IMR-1

  IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 26 μM.

  Cat# S8280, SKU# S8280-5mg, 5mg, $117.00 Ask
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  Spautin-1

  Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

  Cat# S7888, SKU# S7888-50mg, 50mg, $447.00 Ask
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  JANEX-1

  JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an...

  Cat# S5903, SKU# S5903-25mg, 25mg, $397.00 Ask
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  TPI-1

  TPI-1 (Tyrosine Phosphatase Inhibitor 1) is a potent inhibitor of SHP-1 with IC50 of 40 nM for...

  Cat# S6570, SKU# S6570-10mM/1mL, 10mM/1mL, $177.00 Ask
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  1-Octacosanol

  1-Octacosanol (n-Octacosanol, Octacosyl alcohol, Octanosol, Montanyl alcohol, Cluytyl alcohol)...

  Cat# S5161, SKU# S5161-25mg, 25mg, $97.00 Ask
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  4EGI-1

  4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM....

  Cat# S7369, SKU# S7369-100mg, 100mg, $777.00 Ask

  Cited in: Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

  Susanta Chatterjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...
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  G6PDi-1

  G6PDi-1 is an effective inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 depletes...

  Cat# S9617, SKU# S9617-5mg, 5mg, $270.00 Ask
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  1-Phenylbiguanide

  1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3)...

  Cat# S2578, SKU# S2578-25mg, 25mg, $97.00 Ask
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  Necrostatin-1

  Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

  Cat# S8037, SKU# S8037-1g, 1g, $970.00 Ask

  Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

  Johnson Ung, et al., bioRxiv - Cancer Biology 2023

  Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...