4EGI-1
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. 4EGI-1 specifically inhibits the function of mTOR by blocking the activation of 4E-BP1. 4EGI-1 induces apoptosis.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7369 |
| Sku # | S7369-10mg |
| Pricing | 10mg, $197.00 |
Citations for this product:
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bioRxiv - Cell Biology 2023Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...