1 4 Nitrophenyl cyclobutanecarbonitrilefrom Selleck Chemicals

Nodinitib-1

Nodinitib-1(ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits...

Cat# S2863, SKU# S2863-10mM/1mL, 10mM/1mL, $100.00 Ask

RPI-1

RPI-1 inhibits proliferation of human papillary thyroid carcinoma cell line TPC-1 by inducing...

Cat# E2682, SKU# E2682-5mg, 5mg, $129.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-10mM/1mL, 10mM/1mL, $107.00 Ask

M2I-1

M2I-1 is an inhibitor of Mad2 (mitotic arrest deficient 2) targeting the binding of Mad2 to...

Cat# S0187, SKU# S0187-5mg, 5mg, $427.00 Ask

IQ-1

IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous...

Cat# S8248, SKU# S8248-10mg, 10mg, $97.00 Ask

1-Aminobenzotriazole

1-Aminobenzotriazole (ABT, 3-Aminobenzotriazole, 1-Benzotriazolylamine, NSC 114498, NSC 656987)...

Cat# S6886, SKU# S6886-25mg, 25mg, $97.00 Ask

1-Azakenpaullone

1-Azakenpaullone (1-Akp) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM,...

Cat# S7193, SKU# S7193-10mM/1mL, 10mM/1mL, $379.00 Ask

Cited in: Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

Isabella Palazzo, et al., bioRxiv - Neuroscience 2022

Quote: ... and a cocktail of three different GSK3β inhibitors (referred to as ABC) which included 1-Azakenpaullone (1-AP; 500 ng/dose; Selleck Chemicals; S7193), BIO (500 ng/dose ...

BTR-1

BTR-1 induces cytotoxicity in a time- and concentration-dependent manner on leukemia cell line...

Cat# S0307, SKU# S0307-5mg, 5mg, $317.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-1g, 1g, $1270.00 Ask

PRIMA-1

PRIMA-1 (2,2-Bis(hydroxymethyl)-3-quinuclidinone) is a mutant p53 reactivator. It induces...

Cat# S7723, SKU# S7723-50mg, 50mg, $397.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-10mg, 10mg, $147.00 Ask

1-Methylpyrrolidine

1-Methylpyrrolidine is extensively used in the synthesis of pyrrolidine based ionic liquids.

Cat# S6216, SKU# S6216-25ul, 25ul, $97.00 Ask

HCH6-1

HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has...

Cat# S0547, SKU# S0547-5mg, 5mg, $187.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-100mg, 100mg, $727.00 Ask

Vacuolin-1

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis...

Cat# S6912, SKU# S6912-25mg, 25mg, $357.00 Ask

Nodinitib-1

Nodinitib-1(ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits...

Cat# S2863, SKU# S2863-10mg, 10mg, $110.00 Ask

OSMI-1

OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 μM for full...

Cat# S9835, SKU# S9835-5mg, 5mg, $129.00 Ask

G-1

G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30,...

Cat# S0851, SKU# S0851-25mg, 25mg, $1170.00 Ask

1-Iodoadamantane

1-Iodoadamantane (Adamantyl iodide) is a chemical.

Cat# S9371, SKU# S9371-25mg, 25mg, $97.00 Ask

JANEX-1

JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an...

Cat# S5903, SKU# S5903-5mg, 5mg, $127.00 Ask

Leukadherin-1

Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion...

Cat# S8306, SKU# S8306-50mg, 50mg, $297.00 Ask

1-Deoxynojirimycin

1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most...

Cat# S3839, SKU# S3839-5mg, 5mg, $97.00 Ask

RI-1

RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.

Cat# S8077, SKU# S8077-50mg, 50mg, $570.00 Ask

AMG-1

AMG-1 (c-Met/RON Dual Kinase Inhibitor, RON-IN-1) is a potent inhibitor of human c-Met and RON...

Cat# S0361, SKU# S0361-5mg, 5mg, $470.00 Ask

TAI-1

TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.

Cat# S7495, SKU# S7495-5mg, 5mg, $147.00 Ask

Mdivi-1

Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of...

Cat# S7162, SKU# S7162-10mM/1mL, 10mM/1mL, $79.00 Ask

Chroman 1

Chroman 1 is a highly potent and selective ROCK inhibitor with IC50 of 1 pM and 52 pM against...

Cat# E1261, SKU# E1261-5mg, 5mg, $279.00 Ask

Apostatin-1

Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal...

Cat# S9705, SKU# S9705-25mg, 25mg, $470.00 Ask

4EGI-1

4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM....

Cat# S7369, SKU# S7369-10mM/1mL, 10mM/1mL, $219.00 Ask

Cited in: Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

Susanta Chatterjee, et al., bioRxiv - Cell Biology 2023

Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...

Rbin-1

Rbin-1 (Ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It...

Cat# S8376, SKU# S8376-1mg, 1mg, $107.00 Ask

BTZO-1

BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats...

Cat# S0539, SKU# S0539-5mg, 5mg, $117.00 Ask

NL-1

The mitochondrial mitoNEET ligand NL-1 is a mitoNEET inhibitor, which induces a...

Cat# S0767, SKU# S0767-10mg, 10mg, $149.00 Ask

Rbin-1

Rbin-1 (Ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It...

Cat# S8376, SKU# S8376-5mg, 5mg, $327.00 Ask

PRIMA-1

PRIMA-1 (2,2-Bis(hydroxymethyl)-3-quinuclidinone) is a mutant p53 reactivator. It induces...

Cat# S7723, SKU# S7723-10mg, 10mg, $97.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-10mM/1mL, 10mM/1mL, $147.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

1-Deoxynojirimycin

1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most...

Cat# S3839, SKU# S3839-10mM/1mL, 10mM/1mL, $117.00 Ask

BLT-1

BLT-1(Block lipid transport-1), a thiosemicarbazone copper chelator, is a selective inhibitor of...

Cat# S0857, SKU# S0857-5mg, 5mg, $227.00 Ask

Chroman 1

Chroman 1 is a highly potent and selective ROCK inhibitor with IC50 of 1 pM and 52 pM against...

Cat# E1261, SKU# E1261-25mg, 25mg, $837.00 Ask

Tenovin-1

Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and...

Cat# S8000, SKU# S8000-10mg, 10mg, $70.00 Ask

MZ-1

MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd...

Cat# S8889, SKU# S8889-2mg, 2mg, $109.00 Ask

M2I-1

M2I-1 is an inhibitor of Mad2 (mitotic arrest deficient 2) targeting the binding of Mad2 to...

Cat# S0187, SKU# S0187-25mg, 25mg, $1289.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-1g, 1g, $1970.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

1-Methylnaphthalene

1-Methylnaphthalene is an organic compound.

Cat# S6277, SKU# S6277-25ul, 25ul, $97.00 Ask

4EGI-1

4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM....

Cat# S7369, SKU# S7369-10mg, 10mg, $197.00 Ask

Cited in: Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

Susanta Chatterjee, et al., bioRxiv - Cell Biology 2023

Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...

ITD-1

ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

Cat# S6713, SKU# S6713-5mg, 5mg, $97.00 Ask

G-1

G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30,...

Cat# S0851, SKU# S0851-1mg, 1mg, $127.00 Ask

Spautin-1

Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

Cat# S7888, SKU# S7888-10mM/1mL, 10mM/1mL, $117.00 Ask

HCH6-1

HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has...

Cat# S0547, SKU# S0547-25mg, 25mg, $557.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-5mg, 5mg, $97.00 Ask

OF-1

OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively.

Cat# S7681, SKU# S7681-25mg, 25mg, $347.00 Ask

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