1R 2R 1 2 Bis 2 bromophenyl N1 N2 dimethylethane 1 2 diaminefrom Selleck Chemicals

HOIPIN-1

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC)...

Cat# S6396, SKU# S6396-5mg, 5mg, $217.00 Ask

Apostatin-1

Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal...

Cat# S9705, SKU# S9705-5mg, 5mg, $157.00 Ask

PAC-1

PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known...

Cat# S2738, SKU# S2738-10mg, 10mg, $90.00 Ask

MZ-1

MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd...

Cat# S8889, SKU# S8889-5mg, 5mg, $217.00 Ask

JC-1

JC-1 (CBIC2, NK 1420), a fluorescent lipophilic carbocyanine dye, is a mitochondrial potential...

Cat# S9784, SKU# S9784-5mg, 5mg, $427.00 Ask

Torin 1

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

Cat# S2827, SKU# S2827-200mg, 200mg, $1870.00 Ask

Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

Quote: ... Torin 1 (Selleck Chemicals, S2827).

» View all citations

Vacuolin-1

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis...

Cat# S6912, SKU# S6912-10mM/1mL, 10mM/1mL, $137.00 Ask

BMS-1

BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

Cat# S7911, SKU# S7911-25mg, 25mg, $497.00 Ask

TPCA-1

TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits...

Cat# S2824, SKU# S2824-10mg, 10mg, $170.00 Ask

FSL-1

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to...

Cat# S8428, SKU# S8428-5mg, 5mg, $927.00 Ask

ITD-1

ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

Cat# S6713, SKU# S6713-10mM/1mL, 10mM/1mL, $117.00 Ask

HA14-1

HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.

Cat# S1071, SKU# S1071-50mg, 50mg, $170.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-100mg, 100mg, $997.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also...

Cat# S7434, SKU# S7434-1mg, 1mg, $270.00 Ask

Cited in: Targeting neuronal activity-regulated neuroligin-3 dependency for high-grade glioma therapy

Humsa S. Venkatesh, et al., bioRxiv - Neuroscience 2017

Quote: ... TAPI-1 at 20uM (ADAM17 inhibitor; S7434; Selleck Chemicals); GI 254023X at 200nM (ADAM10 inhibitor ...

Torin 1

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

Cat# S2827, SKU# S2827-10mg, 10mg, $170.00 Ask

Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

Quote: ... Torin 1 (Selleck Chemicals, S2827).

» View all citations

WQ 1

WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and...

Cat# E0388, SKU# E0388-5mg, 5mg, $227.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-10mM/1mL, 10mM/1mL, $117.00 Ask

RCM-1

RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia...

Cat# S6898, SKU# S6898-25mg, 25mg, $717.00 Ask

BTB-1

BTB-1 is a novel, selective and reversible inhibitor of the mitotic motor protein Kif18A with...

Cat# S6796, SKU# S6796-5mg, 5mg, $97.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-25mg, 25mg, $870.00 Ask

NQDI-1

NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic...

Cat# S8289, SKU# S8289-50mg, 50mg, $397.00 Ask

Spautin-1

Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

Cat# S7888, SKU# S7888-1g, 1g, $1470.00 Ask

LCS-1

LCS-1 is an inhibitor of superoxide dismutase 1(SOD1) with IC50 of 1.07 μM.

Cat# E2832, SKU# E2832-5mg, 5mg, $70.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-10mg, 10mg, $97.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

A2ti-1

A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)...

Cat# E1421, SKU# E1421-5mg, 5mg, $297.00 Ask

NGI-1

NGI-1 is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase...

Cat# S8750, SKU# S8750-10mM/1mL, 10mM/1mL, $99.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-5mg, 5mg, $147.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

BMS-1

BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

Cat# S7911, SKU# S7911-10mM/1mL, 10mM/1mL, $167.00 Ask

SC-1

SC-1 (1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7), a...

Cat# S0986, SKU# S0986-5mg, 5mg, $427.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-10mM/1mL, 10mM/1mL, $157.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-25mg, 25mg, $297.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-100mg, 100mg, $270.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

MID-1

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction,...

Cat# E0794, SKU# E0794-5mg, 5mg, $209.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-50mg, 50mg, $570.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-5mg, 5mg, $107.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-5mg, 5mg, $290.00 Ask

Anti-Siglec-2 / CD22 (NCI m972)

Anti-Siglec-2 / CD22 (NCI m972) is a humanized monoclonal antibody targeting CD22, a Siglec...

Cat# A3058, SKU# A3058-1mg, 1mg, $539.00 Ask

Anti-ACVR1 / ALK-2 (DS-6016a)

Anti-ACVR1 / ALK-2 (DS-6016a) monoclonal antibody targeting ALK-2. It can be used in the...

Cat# A2621, SKU# A2621-1mg, 1mg, $539.00 Ask

Anti-Siglec-2 / CD22 (NCI m971)

Anti-Siglec-2 / CD22 (NCI m971) is a humanized monoclonal antibody targeting CD22, a Siglec...

Cat# A3057, SKU# A3057-1mg*25, 1mg*25, $5070.00 Ask

Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Phosphatase Inhibitor Cocktail for phosphorylation protection is provided in a 2 tube formula at...

Cat# B15002, SKU# B15002-(1mL A 1mL B) x 10, (1mL A 1mL B) x 10, $384.00 Ask

4-Chloro-2-(trifluoroacetyl)aniline hydrochloride

4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is a HIV-1 RT (HIV reverse transcriptase) inhibitor.

Cat# S5423, SKU# S5423-25mg, 25mg, $127.00 Ask

AZD5153 6-hydroxy-2-naphthoic acid

AZD5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available...

Cat# S8344, SKU# S8344-25mg, 25mg, $490.00 Ask

Anti-Siglec-2 / CD22 (NCI m972)

Anti-Siglec-2 / CD22 (NCI m972) is a humanized monoclonal antibody targeting CD22, a Siglec...

Cat# A3058, SKU# A3058-1mg*25, 1mg*25, $5070.00 Ask

Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Phosphatase Inhibitor Cocktail for phosphorylation protection is provided in a 2 tube formula at...

Cat# B15001, SKU# B15001-1 mL A + 1mL B, 1 mL A + 1mL B, $54.00 Ask

Anti-Siglec-2 / CD22 (NCI m971)

Anti-Siglec-2 / CD22 (NCI m971) is a humanized monoclonal antibody targeting CD22, a Siglec...

Cat# A3057, SKU# A3057-1mg, 1mg, $539.00 Ask

AZD5153 6-hydroxy-2-naphthoic acid

AZD5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available...

Cat# S8344, SKU# S8344-10mM/1mL, 10mM/1mL, $309.00 Ask

Anti-Siglec-2 / CD22 (NCI m972)

Anti-Siglec-2 / CD22 (NCI m972) is a humanized monoclonal antibody targeting CD22, a Siglec...

Cat# A3058, SKU# A3058-1mg*5, 1mg*5, $1690.00 Ask

(S)-2-Hydroxy-3-phenylpropanoic acid

(S)-2-Hydroxy-3-phenylpropanoic acid (L-(-)-3-Phenyllactic acid,...

Cat# S6271, SKU# S6271-25mg, 25mg, $97.00 Ask

2'-Deoxyuridine 5'-monophosphate disodium salt

2’-Deoxyuridine 5’-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase...

Cat# S3169, SKU# S3169-25mg, 25mg, $107.00 Ask

Pherocon (4-(4-Acetoxyphenyl)-2-butanone)

Pherocon (4-(4-Acetoxyphenyl)-2-butanone, 4-(p-Acetoxyphenyl)-2-butanone, 4--(3-Oxobutyl)phenyl...

Cat# S5348, SKU# S5348-25mg, 25mg, $97.00 Ask

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