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251 - 300 of 1376 citations since 2019

• MAPK/ERK Activation in Macrophages Promotes Leishmania Internalization and Pathogenesis

  Umaru Barrie, et al., bioRxiv - Microbiology 2023

  Quote: ... medium containing 10 μM trametinib (Selleck Chemicals, Houston, TX), PMA (Selleck Chemicals) ...
• MAPK/ERK Activation in Macrophages Promotes Leishmania Internalization and Pathogenesis

  Umaru Barrie, et al., bioRxiv - Microbiology 2023

  Quote: ... PMA (Selleck Chemicals), or 0.1% dimethyl sulfoxide (DMSO ...
• Genetic activation of canonical RNA interference in mice

  Valeria Buccheri, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 3 µM CHIR99021 (Selleck Chemicals), penicillin (100 U/mL) ...
• Nucleocytoplasmic transport rates are regulated by cellular processes that modulate GTP availability

  Kelsey L. Scott, et al., bioRxiv - Cell Biology 2023

  Quote: ... Importazole (Selleck Chemicals, 40 µM, 1 hr) was used to inhibit Importin β activity ...
• The role of satellite cell-derived TRIM28 in mechanical load- and injury-induced myogenesis

  Kuan-Hung Lin, et al., bioRxiv - Cell Biology 2023

  Quote: ... the mice also received daily intraperitoneal injections of 20 mg/kg Nilotinib (Selleck Chemical) dissolved in DMSO (Thermo Fisher Scientific ...
• Porcine sapovirus protease controls the innate immune response and targets TBK1

  Iliana Georgana, et al., bioRxiv - Microbiology 2023

  Quote: ... MG132 (Selleck chemicals), lactacystin (Cayman) ...
• RAPID RESISTANCE TO BET INHIBITORS IS MEDIATED BY FGFR1 IN GLIOBLASTOMA

  Anna M. Jermakowicz, et al., bioRxiv - Cancer Biology 2023

  Quote: ... JQ1 (Selleck Chemicals, Houston, TX, USA) was added to media for a final concentration of 500 nM and cells were harvested at 0 hours ...
• Patient-Derived Medullary Thyroid Cancer Organoids; a Model for Patient-tailored Drug and PET-Tracer Screening

  Luc H.J. Sondorp, et al., bioRxiv - Cancer Biology 2023

  Quote: ... selpercatinib (Selleck Chemicals) and pralsetinib (Selleck Chemicals ...
• The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

  Valerio E.C. Piscopo, et al., bioRxiv - Cell Biology 2023

  Quote: ... iPSCs are induced towards neural progenitors for 8 DIV using SB31542 (10µM) and DMH-1 (2µM, Selleck Chemicals LLC), patterned with Retinoic Acid (100nM ...
• Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states

  Celeste Riepe, et al., bioRxiv - Cell Biology 2023

  Quote: ... tezacaftor (VX-661, 5 μM, Selleck Chemicals), Corr-4a (2.5 μM ...
• The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy

  Cristiana Dondi, et al., bioRxiv - Cell Biology 2023

  Quote: ... cells were treated with 2 µM Wnt-C59 (Selleck Chemicals, Houston, TX, USA), an inhibitor of WNT pathway ...
• The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy

  Cristiana Dondi, et al., bioRxiv - Cell Biology 2023

  Quote: ... cells were treated with 6 µM CHIR99021 (Selleck Chemicals, Houston, TX, USA) in S12 media (42 ...
• Extracellular matrix topography drives adrenergic to mesenchymal transition in neuroblastoma

  Antonios Chronopoulos, et al., bioRxiv - Cell Biology 2023

  Quote: ... 0.3 and 1 μM in technical triplicates Doxorubicin (Selleck Chemicals) was added at concentration of 0 ...
• Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

  Susanta Chatterjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... or 25 μM 4EGI-1 (Selleck Chemicals, Cat. # S7369) for 24 h before incubation with 2.5 μM of 5FU for the indicated time-points ...

  Product cited:

  

  4EGI-1

  4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM....

  Cat# S7369, SKU# S7369-10mg, 10mg, $197.00 Ask
• Acylation of MLKL impacts its function in necroptosis

  Apoorva J. Pradhan, et al., bioRxiv - Biochemistry 2023

  Quote: ... BV6 was obtained from Selleck Chemicals (Cat. # S7597; CAS: 1001600-56-1) and zVAD-FMK was obtained from Enzo Life Sciences (Cat ...

  Product cited:

  

  BV-6

  BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.

  Cat# S7597, SKU# S7597-100mg, 100mg, $997.00 Ask
• CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue

  Jiacheng Gu, et al., bioRxiv - Genomics 2023

  Quote: ... 1 μM Olaparib (Selleck Chemicals S1060), 1 μM Cisplatin (Sigma-Aldrich P4394) ...

  Product cited:

  

  Olaparib (AZD2281)

  Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in...

  Cat# S1060, SKU# S1060-100mg, 100mg, $370.00 Ask
• Computational modeling of DLBCL predicts response to BH3-mimetics

  Ielyaas Cloete, et al., bioRxiv - Systems Biology 2023

  Quote: ... Cells were plated at 4×105 cells/mL and treated with ABT-199 and AZD5991 (Selleck Chemicals, Houston, TX)33 24 hours before analysis using CellTiter-Glo viability assay (Promega ...
• piggyBac-Mediated Genomic Integration of Linear dsDNA-Based Library for Deep Mutational Scanning in Mammalian Cells

  Yi Wang, et al., bioRxiv - Bioengineering 2023

  Quote: ... and a 10-day selection with puromycin (Selleck Chemicals, Houston, TX, USA) was performed to select the cells with successful genomic integration ...
• Type I interferon signaling induces a delayed antiproliferative response in Calu-3 cells during SARS-CoV-2 infection

  Juliana Bragazzi Cunha, et al., bioRxiv - Microbiology 2023

  Quote: ... baricitinib (Selleck Chemicals, Houston TX), or vehicle at the indicated time points and concentrations ...
• Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance

  Manasi K. Mayekar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... All drugs used for treatment except PBS-108617 were purchased from Selleck Chemicals. For growth assays ...
• Ectodermal Wnt signalling, cell fate determination and polarity of the skate gill arch skeleton

  Jenaid M. Rees, et al., bioRxiv - Developmental Biology 2023

  Quote: ... experimental and control skate embryos were reared at 15°C in petri dishes containing 50μM IWR1 (Selleck chemicals) in artificial seawater or artificial seawater containing an equivalent volume of vehicle (DMSO ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: Drugs used in the paper include ERK inhibitor Vx-11e (Selleck Chemicals), SCH772984 (Selleck Chemicals) ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and GSK1120212 (Selleck Chemicals; ApexBio), JNK inhibitor SP600125 (Selleck Chemicals) ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... PD0325901 (Selleck Chemicals, ApexBio) and GSK1120212 (Selleck Chemicals ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and LY3214996 (Selleck Chemicals); MEK inhibitors U0126 (Tocris) ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... JNK inhibitor SP600125 (Selleck Chemicals), and p38 inhibitor PD169316 (ApexBio) ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Ulixertinib (Selleck Chemicals) and LY3214996 (Selleck Chemicals) ...
• Kinase-modulated bioluminescent indicators enable noninvasive imaging of drug activity in the brain

  Yan Wu, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... SCH772984 (Selleck Chemicals), KO-947 (MedChem Express) ...
• The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers

  William J. E. Frye, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Romidepsin was from Selleck Chemicals (Houston, TX). Purpurin-18 was purchased from Frontier Scientific (Logan ...
• Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells

  Marten A. Fischer, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: SAHA was purchased from Selleck Chemicals, Munich ...
• FK506 binding protein 5 regulates cell quiescence-proliferation decision in zebrafish epithelium

  Yingxiang Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... FK506 was purchased from Selleck Chemicals (Houston, TX). Oligonucleotide primers ...
• Dopamine receptor D2 confers colonization resistance via gut microbial metabolites

  Samantha A. Scott, Jingjing Fu, Pamela V. Chang, bioRxiv - Microbiology 2023

  Quote: ... PKC-8 inhibitor (PKC8i) and MG-132 were purchased from Selleck Chemicals.
• Biological and structural analysis of new potent Integrase-LEDGF allosteric HIV-1 inhibitors

  Erwann Le Rouzic, et al., bioRxiv - Microbiology 2023

  Quote: ... Rilpivirine (RPV) and Elvitegravir (EVG) were purchased from Selleck Chemicals.
• CRISPR-ChIP delineates a Menin-dependent oncogenic DOT1L complex in MLL- leukaemia

  Omer Gilan, et al., bioRxiv - Molecular Biology 2023

  Quote: ... VTP50469 and A-485 were purchased from Selleck chemicals. For each inhibitor doses used ...
• The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

  Aris E. N. Aristodemou, et al., bioRxiv - Microbiology 2023

  Quote: ... and 10 µM raltegravir (Selleck Chemicals, MK-0518), in polystyrene round bottom 5 ml tubes (Corning ...
• The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

  Aris E. N. Aristodemou, et al., bioRxiv - Microbiology 2023

  Quote: ... and 10 µM raltegravir (Selleck Chemicals, MK-0518) at 5% CO2 ...
• Selection of optimal cell lines for high-content phenotypic screening

  Louise Heinrich, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Compound libraries were sourced from Selleck Chemicals LLC ...
• Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons

  Christina Mortensen, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... The two small molecule inhibitors LDN193189 (0.1 μM, S7507, Selleck Chemicals) and SB431542 (10 μM ...
• Cellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline

  Naoyuki Ohta, Lionel Christiaen, bioRxiv - Developmental Biology 2023

  Quote: ... Flavopiridol (146426-40-6; S1230; Selleck chemicals) was diluted into water to 10mM stock ...
• Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells

  Naveen Jain, et al., bioRxiv - Systems Biology 2023

  Quote: ... at a final concentration of 1uM and the DOT1L inhibitor pinometostat (Selleck Chemicals #S7062) at a final concentration of 4uM.

  Product cited:

  

  Pinometostat (EPZ5676)

  Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein...

  Cat# S7062, SKU# S7062-10mg, 10mg, $270.00 Ask
• An extra-circadian function for human CLOCK in the neocortex

  Yuxiang Liu, et al., bioRxiv - Neuroscience 2023

  Quote: ... 100nM LDN-193189 (Selleck Chemicals, #S2618), and 2nM XAV939 (Tocris Bioscience ...
• PIC recruitment by synthetic reader-actuators to polycomb-silenced genes blocks triple-negative breast cancer invasion

  Natecia L. Williams, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... BMI1 inhibitors PTC209 (4.3 μM; Selleck Chemicals, S7372) or PTC596 (20.8 μM ...
• Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons

  Christina Mortensen, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... SU5402 (10 μM, S7667, Selleck Chemicals) and DAPT (10 μM ...
• Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons

  Christina Mortensen, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and DAPT (10 μM, S2215, Selleck Chemicals) were added on days 2-11 ...
• A non-canonical Hippo pathway represses the expression of ΔNp63

  Ana Maria Low-Calle, et al., bioRxiv - Cancer Biology 2023

  Quote: XMU-MP1 (Selleck Chemicals, S8334) is an inhibitor of MST1/2 (33) ...

  Product cited:

  

  XMU-MP-1

  XMU-MP-1 is an inhibitor of MST1/2 with IC50 values of 71.1±12.9 nM and 38.1±6.9 nM against MST1...

  Cat# S8334, SKU# S8334-5mg, 5mg, $270.00 Ask
• A non-canonical Hippo pathway represses the expression of ΔNp63

  Ana Maria Low-Calle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Verteporfin (Selleck Chemicals, S1786) is an inhibitor of YAP binding to the TEAD transcription factors (38).
• “Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression”

  Marie C. Hasselluhn, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Sunitinib (Selleck Chemicals, S7781), recombinant human WIF1 (R&D systems ...
• Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids

  Meri Kalashyan, et al., bioRxiv - Cell Biology 2023

  Quote: ... the inhibitor against SGK2 was purchased from Selleck Chemicals (Catalog No.S7209). SNARF-5F (and -6 ...
• Oncogene-like addiction to aneuploidy in human cancers

  Vishruth Girish, et al., bioRxiv - Cancer Biology 2023

  Quote: ... A similar protocol was followed to assess the sensitivity of A2780 cells to doxorubicin (Selleck Chemicals; cat. no. S1208), gemcitabine (Selleck Chemicals ...
• The histone methyltransferase NSD3 contributes to sister chromatid cohesion and to cohesin loading at mitotic exit

  Grégory Eot-Houllier, et al., bioRxiv - Molecular Biology 2023

  Quote: ... cells were incubated with 1 μM reversine (S7588, Selleck Chemicals) for 3 h or with 100 ng/ml nocodazole (M1404 ...