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4001 - 4050 of 6619 citations for 6 4 METHYLPIPERAZIN 1 YL NICOTINONITRILE since 2019

• Rewiring of the host cell metabolome and lipidome during lytic gammaherpesvirus infection is essential for infectious virus production

  Sarah A. Clark, et al., bioRxiv - Microbiology 2023

  Quote: ... 1:1 ratios of cells to trypan blue were mixed and loaded on dual chambered slides (Biorad # 1450003). Total cell numbers ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... HRP-conjugated secondary antibodies were applied (Immun-Star Goat Anti-Mouse, 1:20,000, 1705047 and Immun-Star Goat Anti-Rabbit, 1:20,000, 1705046, Biorad), and then activated with Clarity Max western ECL (Bio-Rad) ...
• Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping

  Nikki M. McCormack, et al., bioRxiv - Molecular Biology 2023

  Quote: ... a 160kD glycoprotein expressed by murine macrophages 235 (1:100, Bio-Rad clone C1:A3-1, Cat. MCA497) and rabbit anti-laminin (1:50 ...
• Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy

  Susana G Martins, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1 g SDS in 1 L distilled water) using the Mini-PROTEAN® Tetra electrophoresis system (Bio-Rad). Then ...
• Dual action of sphinganine in the plant disease resistance to bacteria

  Eloïse Huby, et al., bioRxiv - Plant Biology 2024

  Quote: ... followed by a 1 h incubation with anti-mouse IgG HRP-conjugated secondary antibodies (Bio-Rad, 1:3000) at room temperature.
• Vole genomics links determinate and indeterminate growth of teeth

  Zachary T. Calamari, et al., bioRxiv - Evolutionary Biology 2024

  Quote: ... We used 1 μL diluted cDNA (1:3 in ddH2O) and iTaq Universal SYBR Green Supermix (Bio-rad) in the Bio-rad CFX96 real-time PCR detection system for qPCR experiments ...
• SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

  Christopher J. Neufeldt, et al., bioRxiv - Microbiology 2020

  Quote: ... Sheep and-TGN46 (Biorad:AHP500G, IF-1:200); Mouse anti-Actin (Sigma Aldrich ...
• Dexamethasone Inhibits Cytokine-Induced, DUOX2-Related VEGF-A Expression and DNA damage in Human Pancreatic Cancer Cells and Growth of Pancreatic Cancer Xenografts

  Yongzhong Wu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... and CD3 (BioRad #MCA1477, 1:100 60’). These antibodies recognize murine epitopes ...
• PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-tubulin (1:2000) (Bio-Rad, MCA77G), anti-PIE-1(P4G5 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-WIPI2 (1:100, Bio-Rad); rabbit anti-ATG9 (1:100 ...
• “A distinct neutrophil population invades the central nervous system during pancreatic cancer”

  Kevin G. Burfeind, et al., bioRxiv - Immunology 2019

  Quote: ... CD206 (Bio-rad, rat, MR5D3, 1:1000), ER-TR7 (Abcam ...
• An inducible Cre mouse line to sparsely target nervous system cells, including Remak Schwann cells

  Darshan Sapkota, Joseph D. Dougherty, bioRxiv - Neuroscience 2019

  Quote: ... rat anti-MBP (Biorad, MCA409S, 1:100), goat anti-Gfap (Abcam ...
• Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling

  Beatriz Garcia-Diaz, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-F8/40 (1:100, BioRad, MCA497R), anti-Collagen 4(1:400 ...
• Thymosin β4 mediates vascular protection via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

  Sonali Munshaw, et al., bioRxiv - Cell Biology 2019

  Quote: ... Rat anti-CD68 (1:100; BioRad; MCA1957); Rabbit anti-SM-MHC (1:1000 ...
• Thymosin β4 preserves vascular smooth muscle phenotype in atherosclerosis via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

  Sonali Munshaw, et al., bioRxiv - Pathology 2021

  Quote: ... Rat anti-CD68 (1:100; BioRad; MCA1957); Rabbit anti-Caldesmon (1:250 Abcam ...
• A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation

  Courtney M. Jackson, et al., bioRxiv - Immunology 2021

  Quote: ... CD88 (P12/1) (Bio-rad, Hercules, CA). Lung cell suspensions were treated with human IgG to block Fc-receptors and stained for surface markers ...
• Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

  Eric Yau, et al., bioRxiv - Immunology 2021

  Quote: ... and NP (BioRad Cat#MCA400, 1:1000) overnight at 4°C ...
• Methods for quantitative susceptibility and R2* mapping in whole post-mortem brains at 7T

  Chaoyue Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... and PLP (1:1000, Bio-Rad MCA839G) for 1 h ...
• The prion protein is not required for peripheral nerve repair after crush injury

  Anna Henzi, Adriano Aguzzi, bioRxiv - Neuroscience 2020

  Quote: ... rat anti-CD68 (Biorad, MCA1957, 1:200). After three washes in PBS ...
• Pharmacologic manipulation of complement receptor 3 prevents dendritic spine loss and cognitive impairment after acute cranial radiation

  Joshua J. Hinkle, et al., bioRxiv - Neuroscience 2020

  Quote: ... CD68 (Rat; Bio-Rad MCA1957; 1:500), CD11b (Rat ...
• Pharmacologic manipulation of complement receptor 3 prevents dendritic spine loss and cognitive impairment after acute cranial radiation

  Joshua J. Hinkle, et al., bioRxiv - Neuroscience 2020

  Quote: ... CD11b (Rat; Bio-Rad MCA74G; 1:500) and secondary antibodies Alexa-Fluor Goat x Rabbit 647 (Invitrogen ...
• IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis

  Vincent C. Auyeung, et al., bioRxiv - Cell Biology 2021

  Quote: ... rat anti-CD206 (BioRad MCA2235GA, 1:200). For quantification ...
• The Astrin-SKAP Complex Reduces Friction at the Kinetochore-Microtubule Interface

  Miquel Rosas-Salvans, et al., bioRxiv - Cell Biology 2021

  Quote: ... tubulin (1:2000, rat, Bio-rad, MCA77G). There washes in IF buffer (10 min each ...
• Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

  Monika Lakk, et al., bioRxiv - Cell Biology 2021

  Quote: ... followed by anti-mouse (1:5000, BioRad) or anti-rabbit (1:5000 ...
• Deficiency of complement component C1Q prevents cerebrovascular damage and white matter loss in a mouse model of chronic obesity

  Leah C. Graham, et al., bioRxiv - Neuroscience 2020

  Quote: ... rat anti-CD68 (1:100, Bio-Rad), rabbit anti-C1QA (1:100 ...
• Assessing extracellular vesicles from bovine mammary gland epithelial cells cultured in FBS-free medium

  G. Silvestrelli, et al., bioRxiv - Physiology 2021

  Quote: ... anti CD9 (1:250, MM2/57, Biorad). After 3 washes in TBST ...
• Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts

  Mirjam Pennauer, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-TGN46 (1:1000, BioRad AHP500G). Samples were washed and incubated with fluorescent secondary antibodies diluted in 1% BSA in PBS for 1 h (1:400 ...
• Microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer disease

  Jennifer Hua, et al., bioRxiv - Neuroscience 2022

  Quote: ... donkey anti-CD68 (1:300, Biorad, MCA1957A488T), mouse anti-6E10 (Biolegend SIG-39320-0200) ...
• Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

  Inamul Kabir, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-CD68 (1:200, Bio-Rad, MCA1957), directly conjugated Cy3 anti-SMA (1:500 ...
• Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice

  Suzanne Lam, et al., bioRxiv - Neuroscience 2022

  Quote: ... CD68 (Serotec – Biorad MCA 1957, 1/800) or GFAP (Dako Z0334 ...
• The canonical Wnt signaling pathway is not a promising therapeutic target for PNS regeneration enhancement

  Nikita Mehta, Maia Vardy, Benayahu Elbaz, bioRxiv - Neuroscience 2022

  Quote: ... and MBP (BioRad, aa82-87 1:500). Confocal images of the sciatic nerves were taken with a Leica SP2-AOBS laser scanning microscope using a 20x ...
• In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

  Gabriel Matos-Rodrigues, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-BrdU (1:100, Bio-Rad #OBT0030G), anti-PLZF (1:50 ...
• Kidney failure alters parathyroid Pin1 phosphorylation and parathyroid hormone mRNA binding proteins leading to secondary hyperparathyroidism

  Alia Hasan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... PTH (1:1000, Bio-Rad, Hercules, California). Fluorochrome–conjugated secondary antibodies Cy3 and Cy5 (Bethyl ...
• BDSF is a degradation-prone quorum-sensing signal detected by the histidine kinase RpfC of Xanthomonas campestris pv. campestris

  Xiu-Qi Tian, Yao Wu, Zhen Cai, Wei Qian, bioRxiv - Microbiology 2022

  Quote: ... Bio-Beads (beads:detergent = 10:1; Bio-Rad) were added to remove the detergent and the solution was stirred gently at 4 °C overnight ...
• Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel

  Jianlong Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... rat anti-CD68 (1:400, Biorad, MCA1957), rabbit anti-CD3 (1:200 ...
• Complement C3-dependent glutamatergic synapse elimination in the developing hippocampus is region- and synapse-specific

  Eric W. Salter, et al., bioRxiv - Neuroscience 2020

  Quote: ... Rat anti-CD68 (1:250, BioRad, MCA1957); Rat anti-MBP (1:250 ...
• Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer’s-related mice

  Mickael Audrain, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-CD68 (1:500, Bio-Rad, #MCA1957); anti-6E10 (1:1000 ...
• Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model

  Dan Xia, et al., bioRxiv - Neuroscience 2021

  Quote: ... rat anti-CD68 (BioRad, MCA1957A; 1:500), goat anti-Iba1 (Novus ...
• Telomeric Double Strand Breaks Facilitate Formation of 5’ C-Rich Overhangs in G1 Human Cells

  Christopher B Nelson, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Rat anti-BrdU (BioRad OBT0030, 1:200), Rabbit Anti-phospho S15 p53 (Abcam Ab18128-50 ...
• Sustained TREM2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease

  Rahul Dhandapani, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rat anti-CD68 (1:500; Biorad, MCA1957), Goat anti-Olig2 (1:300 ...
• Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

  Stefan A. Berghoff, et al., bioRxiv - Neuroscience 2021

  Quote: ... Then anti-BrdU (MCA2483T, Biorad; 1:500) was added in blocking buffer and incubated overnight ...
• Rabies anterograde monosynaptic tracing reveals organization of spinal sensory circuits

  Sofia Pimpinella, Niccolò Zampieri, bioRxiv - Neuroscience 2021

  Quote: ... sheep anti-GFP 1:2000 (Bio-rad), chicken anti-PV 1:10000 (de Nooij et al. ...
• Single cell transcriptomics reveals functionally specialized vascular endothelium in brain

  Hyun-Woo Jeong, et al., bioRxiv - Physiology 2022

  Quote: ... rat anti-CD206 (BioRad MCA2235T, 1:100), rabbit anti-GFAP (DAO Z0334 ...
• Deconstructing cold-induced brown adipocyte neogenesis in mice

  Rayanne B. Burl, et al., bioRxiv - Cell Biology 2022

  Quote: ... F4/80 (rat, 1:125; Bio-Rad); lens culinaris agglutinin ...
• LIR-dependent LMX1A/LMX1B autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience

  Natalia Jiménez-Moreno, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-WIPI2 (BioRad, MCA5780GA: IF, 1:400). Secondary antibodies for immunoblotting were ...
• Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

  Morayma M. Temoche-Diaz, et al., bioRxiv - Biochemistry 2019

  Quote: ... acrylamide:bisacrylamide (29:1) (Bio-Rad, Hercules, CA), made with Tris-glycine buffer were prerun for 30min at 200V in the cold room ...
• A porcine ex vivo lung perfusion model to investigate bacterial pathogenesis

  Amy Dumigan, et al., bioRxiv - Microbiology 2019

  Quote: ... total STAT6 (1:1000, BioRad #170-6516), phospho-STAT3 (Y705 ...
• HTT silencing delays onset and slows progression of Huntington’s disease like phenotype: Monitoring with a novel neurovascular biomarker

  Hongshuai Liu, et al., bioRxiv - Neuroscience 2020

  Quote: ... Collagen □ (2150-1470, 1:100, BioRad, USA), Acta-2(C6198 ...
• The impact of phosphorylated Pten at threonine 366 on cortical connectivity and behaviour

  Julia Ledderose, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-BrdU rat (1:250, Biorad, OBT0030), anti-Cre rabbit (1:1000 ...
• Pressure overload leads to coronary plaque formation, progression and myocardial events in ApoE-/- mice

  Alice Marino, et al., bioRxiv - Pathology 2019

  Quote: ... anti-CD68 antibody (1:200, MCA1957; BioRAD) and anti-collagen I antibody (1:200 ...