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Citations for The Jackson Laboratory :
1651 - 1700 of 1736 citations for 6 Ethyl 2 4 Pyrimidinediamine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Physiology 2023Quote: Mst1/2 floxed mice (STK3f/f/STK4f/f mice were purchased from The Jackson Laboratory (Stock # 017635, JAX) and crossed with C57BL/6J to generate Mst1 floxed mice (Mst1f/f ...
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bioRxiv - Physiology 2023Quote: ... and AXIN1/2-MKO mice by crossing AXIN1/2F/F mice with HSA-CreERT2 mice (#025750; Jackson Laboratory). Muscular AXIN1 and AXIN2 from the AXIN1/2F/F ...
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bioRxiv - Neuroscience 2020Quote: ... 4-7 and Supplementary Figure 7 were obtained from B6;C3-Tg(Scnn1a-cre)3Aibs/J (JAX #009613, Jackson Laboratory, Bar Harbor, USA) mice crossed with C57 mice (otherwise called Scnn1a-Cre) ...
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bioRxiv - Cancer Biology 2020Quote: ... and orthotopically engrafted onto the second mammary fat pad of 4 weeks old Balb/c mice (2.5x104 cells/mouse) (Jackson Labs, Bar Harbor, ME). Primary tumor growth and metastasis development were assessed via weekly bioluminescent imaging ...
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bioRxiv - Cancer Biology 2021Quote: ... and one piece was implanted into the cleared 4th mammary fat pad of each 4-week-old female FVBN mice (Jackson Laboratory Stock 001800). Mice were maintained on doxycycline diet (Bio-Serv #S3888 ...
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bioRxiv - Genomics 2023Quote: ... Test groups consisting of five male and five female A/J mice aged 4-5 weeks were purchased from Jackson Labs (stock #000646) and infected via intranasal instillation ...
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bioRxiv - Neuroscience 2020Quote: ... Ten mice (8 male, 2 female) were obtained by crossing VGAT-IRES-Cre (Jackson Labs: 028862; B6J.129S6(FVB)-Slc32a1tm2(cre)Lowl/MwarJ)48 with Ai32 (Jackson Labs ...
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bioRxiv - Neuroscience 2020Quote: ... We used 2-month old male or female VGluT2-IRES-Cre transgenic mice (The Jackson Laboratory, RRID: IMSR_JAX:016963). All mice were either housed alone or with a single sibling after the surgery.
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bioRxiv - Neuroscience 2019Quote: ... We also used the tamoxifen (tx) inducible pan-interneuronal Dlx1/2-Cre-ERT2 (The Jackson Laboratory, Stock No: 014600) crossed with the same reporter and Sox6 loxp background ...
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bioRxiv - Neuroscience 2020Quote: ... 2 male & 3 female mice received eYFP injections) mice of both sexes were used (Jackson Labs, Bar Harbor, ME). D1-Cre mice have Cre-recombinase targeted to the Drd1a locus ...
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bioRxiv - Neuroscience 2023Quote: C57BL/6J (2 months old and 18 months old, male, 22-30g, strain# 664, Jackson Laboratories; Bar Harbor, ME), B6.Cg-Apoetm1.1(APOE*4)AdiujAppem1AdiujTrem2em1Adiuj/J (18 months old ...
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bioRxiv - Neuroscience 2024Quote: ... a total of 24 C57BL/6J mice of both sexes (2-18 months old, 18-35 g, Jackson Laboratory) were used ...
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bioRxiv - Neuroscience 2023Quote: ... All experiments were conducted on adult (8-16 weeks old) C57BL/6J mice (5 males, 2 females, Jackson Laboratory). Mice were group housed with standard mouse chow and water provided ad libitum before viral injection (see below) ...
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bioRxiv - Molecular Biology 2023Quote: ... Conditional heart frataxin (Fxn) exon-2 KO mice (Fxnflox/null::MCK-Cre) were purchased from Jackson Laboratory (stock #029720).
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bioRxiv - Cancer Biology 2023Quote: ... and HF2303 (∼2×106) cells were then orthotopically implanted in male and female Rag1-KO mice (RRID:IMSR_JAX:002216, The Jackson Laboratory). Brain tumor-bearing mice were randomized into four arms ...
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bioRxiv - Neuroscience 2021Quote: ... The study included male and female wild-type C57BL/6J (WT) or appropriately validated optogenetic mice (4-8 weeks old, Jackson Laboratory, Bar Harbor, ME). Parvalbumin (PV)-Cre mice (B6;129P2-Pvalbtm1(cre)Arbr/J ...
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bioRxiv - Systems Biology 2019Quote: ... we washed the cells twice with 1% BSA-PBS and then incubated for 30 minutes at 4°Cwith 1:85 bovine anti-goat IgG labeled with Alexa Fluor 647 (Jackson Laboratories, 805-605-180). Finally ...
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bioRxiv - Systems Biology 2019Quote: ... we washed with 0.1% BSA-PBS and then incubated for 30 minutes at 4°C with 1:500 donkey anti-mouse IgG labeled with Alexa Fluor 488 (Jackson Laboratories, 715-545-150). We washed the samples again with 0.1% BSA-PBS and then incubated for 10 minutes at 4°C with 1:250 anti-NGFR antibody conjugated directly to PE-Cy7 (Biolegend ...
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bioRxiv - Neuroscience 2022Quote: ... at 1:150 in blocking solution and incubated overnight at 4°C followed by 3 × 10-minute PBS washes and incubation with secondary antibody anti-mouse-Cy3 (Jackson Laboratories, #115-165-003) at 1:500 into secondary solution (blocking solution diluted 1:1000 in PBS ...
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bioRxiv - Neuroscience 2022Quote: ... The mice used in this study are humanized APOE knock-in animals carrying the APOE3 (B6.Cg-Apoeem2(APOE*)Adiuj/J) or APOE4 (B6(SJL)-Apoetm1.1(APOE*4)Adiuj/J) variants (Jackson Laboratory, Bar Harbor, ME, USA). APOE4 animals were purchased as homozygotes ...
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bioRxiv - Immunology 2020Quote: ... This line of mice was crossed with VLA-1 KO mice (2) or CD103 KO mice (B6.129S2(C)-Itgaetm1Cmp/J) (Jackson Laboratories). This study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals as defined by the National Institutes of Health ...
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bioRxiv - Cell Biology 2021Quote: ... for 2 hours and then with Alexa Flour secondary antibody (anti-mouse, 1:500; anti-rabbit, 1:500, Jackson Laboratories) for 1 hour ...
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bioRxiv - Neuroscience 2022Quote: Mating trios (1 male x 2 females) of C57BL/6J and BALB/cJ mice were originally obtained from Jackson laboratory and then bred onsite either at the University of South Carolina School of Medicine or the University of Maryland School of Medicine ...
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bioRxiv - Microbiology 2023Quote: ... Ly6efl/fl mice (originally generated on CD45.2/.2 background) were crossed with CD45.1/.1 mice (#002014, The Jackson Laboratory, ME) to generate Ly6efl/fl ...
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bioRxiv - Pathology 2023Quote: Male young (2 months old) and aged (18 months old) C57BL6 mice were purchased from Jackson Laboratory (Bar Harbor, ME). All mice had access to food and water ad libitum and were on a 12 h/12 h light/dark cycle ...
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bioRxiv - Cancer Biology 2023Quote: Mouse back injections were carried out in 9-week-old NOD/SCID male mice (with IL-2 receptor γ chain null mutation, NOD.Cg-Prkdcscid Il2rψtm1Wjl/SzJ, (the Jackson Laboratory). 2.5 x 105 RFP-SCC13 tumor cells ...
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bioRxiv - Genetics 2023Quote: ... JAX #029463)22 mice were from the first author’s colonies that were rejuvenated at 2-year intervals with breeders from Jackson Laboratories. Endothelial cell (EC)-specific inducible C1galt1 knockdown mice were created by crossing B6.Cdh5(PAC)-Cre-ERT2 mice (provided by Ralf Adams ...
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bioRxiv - Neuroscience 2020Quote: The study was performed in B6 mice (4 months old, n=10, 20 eyes) and BALB/c mice (4 months old, n=10, 20 eyes) purchased from Jackson Labs (Bar Harbor, ME, USA). All procedures were performed in compliance with the Association for Research in Vision and Ophthalmology (ARVO ...
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bioRxiv - Neuroscience 2020Quote: The study was performed in a subset of B6 mice (4 months old n=5, 10 eyes) and BALB/c mice (4 months old, n=5, 10 eyes) purchased from Jackson Labs (Bar Harbor, ME, USA). PVEPs were recorded in anesthetized mice as described in PERG methods section ...
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bioRxiv - Cancer Biology 2021Quote: 012/LVM2/LR10 tumors were generated by injection of 1□×□106 012/LVM2/LR10 cells into the #4 mammary fat pads of NOD-SCID-gamma (NSG) mice from Jackson Laboratories (Bar Harbor, ME USA), as described previously (Wang ...
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bioRxiv - Immunology 2019Quote: ... Plates were washed as above and incubated for 2h with 1:500 dilution of an alkaline phosphatase-conjugated goat F(ab′)2 anti-human IgG (Jackson Laboratories). Plates were washed and developed for 15 min with 100 μl/well of a Sigmafast p-nitrophenyl phosphate solution (Sigma-Aldrich) ...
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bioRxiv - Immunology 2020Quote: ... CAR transduction was measured using anti-CAR antibody Goat F(ab’)2 anti-Human IgG (H+L)-Alexa Fluor 647 (Jackson Laboratories). CD107a degranulation was measured with anti-human CD107a (LAMP-1 ...
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bioRxiv - Neuroscience 2020Quote: 10-17 week old (12 ± 2 weeks, mean ± s.d., N = 45 mice) male C57BL/6J mice (Jackson laboratories, Bar Harbor, ME) were anesthetized with isoflurane (3% induction ...
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bioRxiv - Neuroscience 2020Quote: PCR genotyping was performed on purified tail tips at least 2 times to confirm the genotype according to the protocol by Jackson Laboratory. All work involving mice was approved by the University of Michigan Institutional Animal Care and Use Committee (IACUC ...
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bioRxiv - Cell Biology 2021Quote: Mice possessing loxP sites flanking exon 2 of the Aurka gene [16] were obtained from Jackson Laboratories (B6.129-Aurkatm1.1Tvd/J, #017729). To generate Aurkafl/fl Gdf9-Cre mice ...
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bioRxiv - Neuroscience 2022Quote: ... and incubated with secondary antibodies in PTX at RT for 2 h: 1:200 Dylight 488 goat anti-chicken (Jackson lab), and 1:200 AlexaFluor 546 goat anti-mouse (ThermoFisher) ...
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bioRxiv - Physiology 2020Quote: To generate βARKOMIP mice we crossed mice carrying the AR gene with floxed exon 2 on their X chromosome (ARlox) with the Ins1-Cre/ERT (MIP-Cre+/-) transgenic mouse (Jackson Lab). Generation and characterization of ARlox -/- have been described (24) ...
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bioRxiv - Neuroscience 2022Quote: ... mice for the neurophysiology (Figure 6C-I) and pharmacokinetics (Figure 6A) experiments were 2-3-month-old male C57BL/6J from Jackson Labs. Mice were housed in a barrier facility on a 12/12 light cycle with species-specific heat and humidity and fed a standard laboratory diet with food and water ad libitum ...
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bioRxiv - Developmental Biology 2019Quote: ... Samples with the biotinylated probe were incubated for 2 hr in biotinylated donkey anti-mouse secondary antibody (1:500; Jackson Lab) in WB:PBT solution ...
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bioRxiv - Bioengineering 2022Quote: Mice with channelrhodopsin 2 (ChR2) expression in cardiomyocytes alone were created by cross-breeding one parent (Stock No. 011038, Jackson Labs) having Cre recombinase expression driven by the cardiac-specific alpha myosin-heavy chain promoter (αMyHC)58 with another flox-ChR2-YFP parent (Stock No ...
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bioRxiv - Neuroscience 2022Quote: ... Sections were then washed with PBS and incubated for 2 hr at room temperature with secondary antibody (1:500, AF 647, donkey anti rabbit, #711-605-152, Jackson laboratory) in 1% BSA in PBS ...
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bioRxiv - Neuroscience 2022Quote: ... and were followed by 2 h incubation at RT in a biotinylated secondary antibody goat anti-rabbit (1:1000; Jackson Laboratories) in 0.1M PB ...
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bioRxiv - Immunology 2023Quote: ... while the anti-CD40 antibodies were detected using an Alexa Fluor 488-conjugated goat anti-human-F(ab)2 (Jackson Laboratories). Cells were analyzed using a FACSVerse instrument (BD).
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bioRxiv - Physiology 2023Quote: ... This step was followed by three 10 min washes in PBS and incubation for 2 h with conjugated secondary antibodies (1:200, Jackson Laboratories) and DAPI in PBS at room temperature ...
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bioRxiv - Physiology 2023Quote: ... This step was followed by 6 washes with 1% Triton X-100 in PBS for 15 min and incubation for 2 h with conjugated secondary antibodies (1:200, Jackson Laboratories) and DAPI in PBS at room temperature ...
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bioRxiv - Neuroscience 2023Quote: ... Sections were then washed with PBS and incubated for 2 hr at room temperature with a secondary antibody (1:500, AF 647, donkey anti rabbit, #711-605-152, Jackson laboratory) in 1% BSA in PBS ...
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bioRxiv - Neuroscience 2023Quote: ... and TRAP-2 mice crossed with B6.Cg-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/J (Flex-tdTomato) (Cat. No. 7905, Jackson Labs). Mice were housed in temperature- and humidity-controlled cages ...
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bioRxiv - Cell Biology 2023Quote: ... This step was followed by three 10 min washes in PBS and incubation for 2 h with conjugated secondary antibodies (1:200, Jackson Laboratories) and DAPI in PBS at room temperature ...
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bioRxiv - Neuroscience 2023Quote: ... Cochleae were harvested from Ndp knockout and wild-type mice in which alkaline phosphatase was inserted into exon 2 (Stock No. 011076 Jackson Laboratory) at the ages of postnatal day 3 (P3 ...
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bioRxiv - Neuroscience 2022Quote: ... then processed for 48 hours at 4 degrees with secondary antibodies in blocking solution (1:1000, Alexa Fluor 647 goat anti-rabbit, Jackson Laboratories, plus 1:500 NeuroTrace, Invitrogen). Tissue sections were then rinsed again 3×10 minutes in PBS ...