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Citations for The Jackson Laboratory :
1401 - 1450 of 1736 citations for 6 Ethyl 2 4 Pyrimidinediamine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Developmental Biology 2024Quote: The Tet1tm1Koh line was originally created as a C57Bl/6 (B6) congenic strain and henceforth maintained by regular backcrossing to C57Bl/6J obtained from Jackson Lab. To transfer the Tet1tm1Koh allele to alternative genetic backgrounds ...
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bioRxiv - Neuroscience 2023Quote: ... DS mice carrying an Scn1a KO allele restricted to (specifically in) forebrain GABAergic neurons alone were generated by breeding floxed Scn1a mice with Dlx5/6-Cre mice (Strain#: 008199, Jackson Laboratories). All breeder mice were maintained on a C57BL/6J background for at least 10 generations ...
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bioRxiv - Neuroscience 2023Quote: ... Mice were 8-9 week old male and female C57BL/6 mice bred at PSUCOM or UMSOM with original breeding pairs obtained from Jackson Labs. All mice were pair housed in corn-cob bedding ...
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bioRxiv - Bioengineering 2023Quote: ... with modified injection coordinates and a homogeneous tumor composition with lowered cell density.[35] 6- to 12-week- old female C57B6/J mice (Jackson labs) were used in accordance with the approved Duke Institutional Animal Care and Use Committee (IACUC ...
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bioRxiv - Biophysics 2023Quote: Wild type C57BL/6 mice and mice expressing Cre recombinase (CD4Cre) under the control of the CD4 promoter were purchased from Jackson Laboratories. Odcflox/flox mice were purchased from the KOMP repository ...
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bioRxiv - Cancer Biology 2023Quote: These studies were conducted using C57BL/6 and Tyrosinase-related protein 1 (TRP-1) TCR transgenic mice (Rag-/- BWTRP-1 TCR) purchased from Jackson laboratories. The TRP-1 TCR transgenic mice (Rag-/- BWTRP-1 TCR ...
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bioRxiv - Synthetic Biology 2024Quote: ... Tumors were implanted by injecting 1×105 4T1 cells into the mammary fat pad of 6-week-old female BALB/c mice (Jackson Labs). Lm XFL7 (2×107 CFU/mouse ...
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bioRxiv - Genomics 2024Quote: ... or IDH1-R132Q cells suspended in PBS were implanted subcutaneously into the left flanks of 6–8-week-old female athymic Nu/Nu mice (Jackson Laboratory). Based on previous work on generating xenografts with HT1080 cells79,80 ...
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bioRxiv - Cancer Biology 2024Quote: ... three million tumor cells were injected subcutaneously into 6-weeks-old athymic female nu/nu mice (Stock No: 002019, Jackson Labs) and grown until tumors reached a size of approximately 30 mm3 ...
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bioRxiv - Cancer Biology 2024Quote: ... Animals injected with murine tumor cells were 10-week-old C57BL/6 or TRPV1-Cre::Floxed-DTA mice (The Jackson Laboratory) weighing approximately 24 g ...
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bioRxiv - Cell Biology 2024Quote: 500.000 HCT116 and DLD-1 cells resuspended in 100 µl of PBS were injected subcutaneously into the dorsal flank of 6–8-week-old immunocompromised NOD/SCID female mice (purchased for Jackson laboratory). Tumor size was measured twice a week using calipers ...
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bioRxiv - Animal Behavior and Cognition 2024Quote: ... mice (Stock No: 000664) and Gpr37 knockout mice with a C57BL/6 background (Stock No: 005806) were purchased from Jackson Laboratory and maintained at Duke University Animal Facilities ...
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bioRxiv - Immunology 2020Quote: Wild-type C57BL/6J mice (4 weeks of age) were purchased from Jackson Laboratory. For studies involving ZIKV challenge ...
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bioRxiv - Physiology 2023Quote: PAHSAs: 4–5-week-old conventional chow-fed male C57BL/6J mice (Jackson Labs) were singly-housed and treated with either vehicle (50% PEG400 ...
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bioRxiv - Microbiology 2024Quote: 3-4-weeks-old male and female C3H/HeJ mice (Jackson Laboratory, ME, USA) were housed in groups of 4 in polysulfone cages (29 cm × 19 cm × 12 cm ...
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bioRxiv - Microbiology 2024Quote: 4-week-old male and female C57BL/6J mice (strain #000664; The Jackson Laboratory) were vaccinated two times at 3 week intervals with 10 µg of recombinant protein or PBS control diluted at a 1:1 ratio with Addavax (InvivoGen ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: Mouse AT2 cells were isolated from both wt and uPA knockout (plau-/-) strains of C57BL/6 mice (cat#: 000664 and 002509, respectively. Jackson Laboratory, USA) with a modified protocol as described (Demaio et al. ...
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bioRxiv - Neuroscience 2020Quote: ... A total of 9 C57BL/6 J-Tg(Thy1-GCaMP6s)GP4.3Dkim/J adult mice (IMSR Cat# JAX:024275, RRID:IMSR_JAX:024275; 3 females, 6 males; Jackson Laboratory, Bar Harbor, ME, USA) were used for the imaging in this study ...
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bioRxiv - Neuroscience 2020Quote: AD-transgenic (Tg) (APPSwePS1d9 a.k.a. PSAPP, Supplementary Fig. 1) and C57BL/6 mice were purchased from Jackson Laboratory (Bar Harbor, ME, USA) and bred in-house ...
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bioRxiv - Immunology 2020Quote: C57Bl/6 male and female mice (10-, 16-, and 26-week old) were purchased from Jackson Laboratories (n=5-7 per group). For estrogen receptor-α conditional knockout experiments ...
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bioRxiv - Cell Biology 2021Quote: ... transgenic mice aged 3 months were used for spinal cord microglial cell histology. β-actin-GFP C57BL/6 mice (Okabe et al. 1997) (Jackson Laboratories) aged 3 months were used to derive GFP+ neurospheres to co-culture with microglia BV-2 cells ...
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bioRxiv - Microbiology 2022Quote: ... For the FMT experiment twelve male adult C57BL/6 J mice (age 20 weeks) were purchased from Jackson Laboratory (Bar Harbor, ME) and were acclimatized for 3 weeks before experimentation ...
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bioRxiv - Cancer Biology 2021Quote: ... Human cells were transplanted into sublethally irradiated (200 cGy) 6-9 week-old NOD-scid-Il2rg-null-3/GM/SF (NSGS; The Jackson Laboratory #013062). NSGS mice were transplanted with 1 x 105 cells via intra-tibial injection under anaesthesia with intraperitoneal injection of ketamine/xylazine mixture (2 mg/mouse ...
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bioRxiv - Cancer Biology 2022Quote: ... 1.2 × 106 whole bone marrow from primary transplant recipient mice exhibiting MPN was harvested 6-8 weeks post-transplant and combined with age-matched 0.8 × 106 Cd45.1 (Jackson Laboratories, Bar Harbor, ME) whole bone marrow and transplanted into 6-8 week old lethally irradiated Cd45.1 secondary recipient mice ...
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bioRxiv - Physiology 2019Quote: Unilateral VML injury was performed on the left TA muscle of C57Bl/6 mice ubiquitously expressing mitochondrial Dendra2 green/red photoswitchable monomeric fluorescent protein (Jackson Laboratory, #018385). We elected to use the TA for the imaging rather than the gastrocnemius muscle used for other studies herein ...
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bioRxiv - Cancer Biology 2020Quote: ... Up to two PDX tumor sections approximately 2 mm in diameter were implanted subcutaneously into 6-8-week-old female NOD.Cg-PrkdcSCIDIl2rg tm1Wjl/SzJ (NSG) mice (The Jackson Laboratory, Stock # 005557). Once tumors reached approximately 5-10 mm2 (approximately 3 weeks after implantation) ...
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bioRxiv - Microbiology 2021Quote: ... brains were collected from C57Bl/6 mice 28-30 days post infection or CBA/J mice (The Jackson Laboratory, Bar Harbor, ME) 28-30 days post-infection ...
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bioRxiv - Animal Behavior and Cognition 2020Quote: ... we crossed Emx1-Cre knock-in mice with the Ai9 Cre reporter line Gt(ROSA)26Sortm9(CAG-tdTomato)Hze (C57BL/6) (Jackson Laboratory #007909). We also used conditional Bbs8 knock-out mice (Bbs8flox/flox ...
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bioRxiv - Developmental Biology 2020Quote: ... KIF9 knockout mice were generated by breeding floxed homozygotes with C57BL/6-Tg(Zp3-cre)93Knw/J mice (Jackson Labs catalogue # 003651). Genotyping was performed by PCR of genomic DNA using the 3’SR and 5’SF primers ...
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bioRxiv - Cell Biology 2020Quote: ... and in vitro fertilization (IVF) was performed by the Vanderbilt Genome Editing Resource using female C57BL/6 mice (Jackson Laboratories, stock #000664). In the VEGFR2iΔEC model loxP sites were inserted flanking VEGFR2 exon 3 ...
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bioRxiv - Immunology 2022Quote: Six-to-ten weeks old male or female C57BL/6 Tmem176b (WT) and Tmem176b-/- mice were used (Jackson Lab; Bar Harbor, ME) and bred for up to 20 generations in the Transgenic and Experimental Animals Unit (UATE ...
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bioRxiv - Molecular Biology 2022Quote: ... mice homozygous with floxed Zhx2 alleles (Zhx2f/f) were bred to BL/6 mice expressing Albumin promoter-driven Cre recombinase (Alb-Cre, Jackson Labs #003574) or BL/6 mice expressing E2a promoter-driven Cre recombinase (E2a-Cre ...
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bioRxiv - Neuroscience 2022Quote: Six mice of both sexes (ages 6-12 months) expressing the genetically encoded Ca2+ indicator GCaMP6f primarily in excitatory neurons (Thy1-GCaMP6f; Jackson Laboratories #024339) were used for the imaging studies (Dana et al ...
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bioRxiv - Neuroscience 2022Quote: Male and female 6-to 8-week-old C57BL/6J mice (N=38) obtained from Jackson Laboratories (Bar Harbor, ME; SN: 000664) were kept 5 per cage and maintained on a 12-hour reverse light/dark cycle ...
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bioRxiv - Cancer Biology 2022Quote: ... Five million B16-F10 or BP melanoma cells were injected subcutaneously into 6- to 8-week-old C57BL/6J mice (The Jackson Laboratory, #000664) and monitored every other day for tumor growth ...
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bioRxiv - Microbiology 2024Quote: ... 129P2-Cd40tm1Kik/J) and C57BL/6 mice expressing CD45.1 (B6.SJL-Ptprca Pepcb/BoyJ) were obtained from Jackson Laboratory (Bar Harbor, ME). All mouse strains were subsequently bred at the NIH Clinical Center animal facility ...
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bioRxiv - Microbiology 2023Quote: ... 6-8 week-old K18-hACE2 male mice on the C57BL/6J background (bred in-house, originally obtained from Jackson Labs, #034860) were divided into four groups (n=5 per group ...
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bioRxiv - Cancer Biology 2024Quote: ... cell suspension (HCT116 wt and two separate Rab27B KO clones) was injected into the flanks of 5-6 weeks old athymic nude mice (The Jackson Laboratory, USA). Four mice per group were used with two tumors/mouse ...
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bioRxiv - Molecular Biology 2024Quote: ... using a 21-gauge needle in the right and left flank of each 6-week aged athymic nude mice (JAX002019, Jackson Laboratory®). Tumor size was followed at several points post injection by measuring the length and width of the tumor using a caliper ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: Eight-week-old female C57BL/6 mice (body weight = 18.8 ± 0.2 g) were used in this study (Jackson Laboratory – Bar Harbor, ME). Mice were initially housed five per cage and maintained on a 12-hr light/dark cycle at approximately 22°C and 50% relative humidity in an AAALAC–approved facility ...
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bioRxiv - Immunology 2023Quote: ... This study utilized two mouse strains at 8-12 weeks of age: C57BL/6 wildtype mice from Jackson Laboratories (Bar Harbor, ME) and TLR7−/−/TLR8−/− mice on a C57BL/6 background which were a generous gift from Professor Richard Flavell (22) ...
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bioRxiv - Neuroscience 2023Quote: ... The data from N=115 adult mice (C57BL/6; 80 male and 35 female, obtained from either Jackson Laboratory or Charles River) is used in this study ...
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bioRxiv - Cancer Biology 2023Quote: 1×105 4T07-TGL or 4T1-TGL cells were injected in the fat pad of the 4th mammary gland of 6-week-old NU/J mice (The Jackson laboratory #002019). For the 4T07 experiment ...
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bioRxiv - Bioengineering 2023Quote: The CAG-LC3b-RFP-EGFP transgenic mouse line (C57BL/6-Tg[CAG-RFP/GFP/Map1lc3b]1Hill/J, Jackson Laboratories; Bar Harbor, ME) was used (n = 5 ...
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bioRxiv - Bioengineering 2023Quote: ... PDX studies were performed using 6-8 weeks old male NSG mice (NOD/SCID/IL-2Rγ−/-) (The Jackson Laboratory, Bar Harbor, ME). Animal studies were approved by the University of Virginia Institutional Animal Care and Use Committee and performed in compliance with guidelines from the Public Health Service Policy and Animal Welfare Act of the United States.
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bioRxiv - Immunology 2023Quote: ... Female B6.129S2-IghmtmCgn and B6.SJL-Ptprca Pepcb/Boy mice (6-8 weeks old) were purchased from Jackson Laboratories (Bar Harbor, ME). All experimentation was in compliance with the McMaster University Research Ethics Board.
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bioRxiv - Developmental Biology 2023Quote: ... Vangl2 null allele in C57Bl/6 background was derived by serially crossing Vangl2 ex2-3 floxed mice (Jackson Laboratory stock no. 025174) (59 ...
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bioRxiv - Neuroscience 2024Quote: ... Rab27a and -b double knockout (DKO) mice acquired from Miguel Seabra [34] were crossed with C57BL/6-J mice from Jackson Laboratories (000664) to generate a single KO mouse for Rab27b ...
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bioRxiv - Evolutionary Biology 2024Quote: ... Seven-week-old C57BL/6 female mice and 10-week-old male mice were purchased from Jackson Laboratories (Bar Harbor, ME: 000664). Littermates of the same sex were randomly assigned to experimental groups ...
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bioRxiv - Systems Biology 2024Quote: ... and implanted into the mammary fat pad of 6 to 8-week-old female NOD (NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ) SCID gamma (NSG) mice (Jackson Labs, Strain #005557) for scRNA-seq and therapeutic studies.