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801 - 850 of 10000+ citations for 1 2 Chloropyridin 3 yl 3 3 dimethylazetidin 2 one since 2020

• Mapping PTBP splicing in human brain identifies targets for therapeutic splice switching including SYNGAP1

  Jennine M. Dawicki-McKenna, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 3% SDS (Sigma #L5750), 3.75 mM EDTA (Bio-Rad #1610729 ...
• Molecular Neurobiology of Loss

  Marissa Ann Smail, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3-diaminobenzidine (Sigma Aldrich) with 0.05% hydrogen peroxide ...
• ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

  Surya Prakash Rao Batta, et al., bioRxiv - Cell Biology 2022

  Quote: ... 3% BSA (Sigma-Aldrich), 0.5% Triton X-100 (Sigma-Aldrich) ...
• Enhanced cardiac mitochondrial biogenesis by nitro-oleic acid remedies diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction

  Marion Müller, et al., bioRxiv - Pathology 2024

  Quote: ... SITE+3 (Sigma S5295), 25 mM blebbistatin (Toronto Research Chemicals B592500)) ...
• Protein aggregation is a consequence of the dormancy-inducing membrane toxin TisB in Escherichia coli

  Florian H. Leinberger, et al., bioRxiv - Microbiology 2024

  Quote: ... DiBAC4(3) (Sigma-Aldrich) was added at a final concentration of 1 µg/ml ...
• mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction

  Jay N. Joshi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and #3 (Sigma #P0044) used at 1:100 each ...
• Peptide aggregation-induced immunogenic cell death in a breast cancer spheroid model

  Gokhan Gunay, et al., bioRxiv - Bioengineering 2023

  Quote: ... 3 (Sigma-Aldrich GHS332), differentiating with tap water and acidic ethanol ...
• Natural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex

  Arjen J. Boender, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 mM MgCl2 (Sigma), 0.1% Nonidet P40 Substitute (Sigma) ...
• A quantitative autonomous bioluminescence reporter system with a wide dynamic range for Plant Synthetic Biology

  Camilo Calvache, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... 3% sucrose (Sigma-Aldrich), 0.9% Phytoagar (Duchefa) ...
• A quantitative autonomous bioluminescence reporter system with a wide dynamic range for Plant Synthetic Biology

  Camilo Calvache, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... 3% sucrose (Sigma-Aldrich), 0.9% Phytoagar (Duchefa) ...
• A quantitative autonomous bioluminescence reporter system with a wide dynamic range for Plant Synthetic Biology

  Camilo Calvache, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... 3% sucrose (Sigma-Aldrich), 0.9% Phytoagar (Duchefa) ...
• Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation

  Annabel T. Olson, et al., bioRxiv - Microbiology 2023

  Quote: ... 3% BSA (Sigma #A7906) and 1X PBS (Gibco #14200075 ...
• Meisosomes, folded membrane platforms, link the epidermis to the cuticle in C. elegans

  Dina Aggad, et al., bioRxiv - Cell Biology 2023

  Quote: ... 3-butanedione monoxime (Sigma) for 2 h at room temperature and transferred to a ∼2 mm thick 4 % agarose bed in a petri dish (30 mm) ...
• Multiplexed fluorescence and scatter detection with single cell resolution using on-chip fiber optics for droplet microfluidic applications

  Preksha Gupta, et al., bioRxiv - Bioengineering 2023

  Quote: ... 3-bromobenzotrifluoride (Sigma B59004) was mixed with dSURF oil for refractive index modifications as per requirement ...
• Dimeric Transmembrane Structure of the SARS-CoV-2 E Protein

  Rongfu Zhang, et al., bioRxiv - Biophysics 2023

  Quote: ... 3% Empigen (Millipore Sigma) was then added and the tube was rotated at 4 °C for 2-3 hr prior to centrifugation at 10,000 g for 30 min ...
• Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement

  Haneen S. Alsehli, et al., bioRxiv - Cell Biology 2023

  Quote: ... plus 3% BSA (Sigma) and were incubated overnight at 4°C on a shaker ...
• SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

  Surya Chandra Rao Thumu, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 KCl (Sigma #P5405), 1 MgSO4.7H2O (Sigma #M2773) ...
• SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

  Surya Chandra Rao Thumu, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 KCl (Sigma #P5405), 10 MgSO4.7H2O (Sigma #M2773) ...
• Self-renewing Sox9+ osteochondral stem cells in the postnatal skeleton

  Stephanie Farhat, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1X ITS+3 (Sigma) and 1.25mg/mL Bovine Serum Albumin ...
• ER-to-lysosome Ca²⁺ refilling followed by K⁺ efflux-coupled store-operated Ca²⁺ entry in inflammasome activation and metabolic inflammation

  Hyereen Kang, et al., bioRxiv - Immunology 2023

  Quote: ... 3 mM EGTA (Sigma), 100 nM 2-APB (Sigma) ...
• Investigating the potential of X shredding for mouse genetic biocontrol

  Mark. D. Bunting, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 3 μM CHIR99021 (Sigma), 1 μM PD0325901 (Sigma) ...
• A single cell atlas of the mouse seminal vesicle

  Fengyun Sun, et al., bioRxiv - Genomics 2024

  Quote: ... and 3% BSA (Sigma). The primary and secondary antibodies specifications and dilutions are at 1:500 and 1:2000 ...
• Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila

  Francisco Muñoz-Carvajal, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3-octanol (Sigma, W358118), or a pleasant odor of 2.3-butanedione (Sigma ...
• Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders

  Alex J. Felix, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3% SDS (Sigma #L5750), 3.75 mM EDTA (Bio-Rad #1610729 ...
• Pro-survival roles for p21(Cip1/Waf1) in Non-Small Cell Lung Cancer

  SJ Cutty, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Nutlin-3 (Sigma N6287) was added to a final concentration of 5 μM (A549 and NCI-H460 ...
• A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies

  Xiaolei Liu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and #3 (Sigma #P0044) used 1:100 each ...
• Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose

  Amber Crabtree, et al., bioRxiv - Biophysics 2024

  Quote: ... 1% phosphatase inhibitor cocktails #2 (Sigma P5726-1ML)/#3 (Sigma P0044-1ML), and one cOmplete protease inhibitor tablet (Sigma 04693159001) ...
• Optics-free reconstruction of 2D images via DNA barcode proximity graphs

  Hanna Liao, et al., bioRxiv - Genomics 2024

  Quote: ... 3% acrylamide solution (Sigma), 48 mM Tris–HCl pH 8.0 ...
• Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

  Nadia Vertti-Quintero, et al., bioRxiv - Bioengineering 2024

  Quote: ... 3 μM CHIR99021 (Sigma) and 1 μM PD0325901 (Sigma) ...
• Structure of the TXNL1-bound proteasome

  Jingjing Gao, et al., bioRxiv - Cell Biology 2024

  Quote: ... benzonase (Millipore, 71206-3), and protease inhibitor tablets (Sigma ...
• Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib

  Serena Muratcioglu, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 3 (P0044, Sigma), 50 mM NaF ...
• Contact-based transfer of thymidylate promotes collective tumor growth

  Mohammad A. Siddiqui, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or 3% BSA (Sigma), both prepared in 1X TBS-T (1% Tween20 in Tris Buffer Saline) ...
• Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

  Nadia Vertti-Quintero, et al., bioRxiv - Bioengineering 2024

  Quote: ... 3 μM CHIR99021 (Sigma) and 1 μM PD0325901 (Sigma) ...
• Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit

  James Holder, Shabaz Mohammed, Francis A. Barr, bioRxiv - Cell Biology 2020

  Quote: ... phosphatase inhibitors (Sigma cocktail 3, 1:100 dilution) and 100 nM okadaic acid ...
• Short chain fatty acids enhance expression and activity of the umami taste receptor in enteroendocrine cells via a Gα_i/o pathway

  Matilda Shackley, et al., bioRxiv - Cell Biology 2020

  Quote: ... supplemented with 3-isobutyl-1-methylxanthine (IBMX; Sigma) to inhibit phosphodiesterase cAMP degradation ...
• Mitochondrial uncoupling protein 2 (UCP2), but not UCP3, is sensitive to oxygen concentration in cells

  Karolina E. Hilse, et al., bioRxiv - Cell Biology 2020

  Quote: ... [3-actin (Sigma Aldrich, A544l, dilution 1:10000), Oct 3/4 (Santa Cruz ...
• Delineating the heterogeneity of matrix-directed differentiation towards soft and stiff tissue lineages via single-cell profiling

  Shlomi Brielle, et al., bioRxiv - Cell Biology 2020

  Quote: ... 500 mM 3-isobutyl-1-methylxanthine (Sigma-Aldrich), 1 μM dextran (Sigma-Aldrich) ...
• CRISPR-mediated isogenic cell-SELEX approach for generating highly specific aptamers against native membrane proteins

  Jonah C. Rosch, et al., bioRxiv - Bioengineering 2020

  Quote: ... containing 1% phosphatase inhibitor cocktail 3 (Sigma, P0044) and 1% protease inhibitor cocktail (Sigma ...
• LAMP2A regulates the loading of proteins into exosomes

  João Vasco Ferreira, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Histone 3 1:1000 (Sigma, H0164); anti-Vps4b 1:500 (SCBT ...
• Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans

  Molly A. Matty, et al., bioRxiv - Neuroscience 2021

  Quote: ... Isoamyl alcohol (3-methyl-1-butanol, Sigma 77664), and Benzaldehyde (Sigma 418099 ...
• Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line

  Tina Aumer, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 1 % phosphatase inhibitor cocktail 3 (Sigma P0044-1ML), DNase I ...
• A CRISPR-screen in intestinal epithelial cells identifies novel factors for polarity and apical transport

  Katharina MC Klee, et al., bioRxiv - Cell Biology 2022

  Quote: ... claudin 3 (IF 1:200, #SAB4500435, Sigma-Aldrich), DNP (EM 1:6-1:30 ...
• The Mycobacterium tuberculosis protein O-phosphorylation landscape

  Andrew Frando, et al., bioRxiv - Microbiology 2022

  Quote: ... 1% phosphatase inhibitor cocktail 3 (Sigma, P 0044)) ...
• Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

  Renee F.C. Hein, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 100µM 3-Isobutyl-1-methylxanthine (Sigma, Cat#I5879), 100µM 8-bromoadenosine 3’ ...
• A three-dimensional human adipocyte model of fatty acid-induced obesity

  Vera M. Pieters, et al., bioRxiv - Bioengineering 2022

  Quote: ... 250 μM 3-isobutyl-1-methylxanthine (Sigma-Aldrich), 100 μM indomethacin (Sigma-Aldrich) ...
• Mammary ductal epithelium controls cold-induced adipocyte thermogenesis

  Luis C. Santos, et al., bioRxiv - Cell Biology 2021

  Quote: ... containing 3 mg ml-1 collagenase A (Sigma) and 1.5 mg ml-1 trypsin (Sigma) ...
• Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint

  Vikram Sunkara, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mixed with 1-bromo-3-chloropropane (Sigma Aldrich) and incubated for 10 min ...
• 14-3-3ζ mediates an alternative, non-thermogenic mechanism to reduce heat loss and improve cold tolerance

  Kadidia Diallo, et al., bioRxiv - Physiology 2020

  Quote: ... 0.5mM 3-Isobutyl-1-methylxanthine IBMX (Sigma Aldrich), 1μM dexamethasone (Sigma Aldrich) ...
• 3D soft hydrogels induce human mesenchymal stem cells “deep” quiescence

  David Boaventura Gomes, et al., bioRxiv - Bioengineering 2021

  Quote: ... 0.5 mM 3-Isobutyl-1-methylxanthine (Sigma-Aldrich), and 2.5 μg/ml insulin (Sigma-Aldrich) ...
• A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome

  Gabriella Lania, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Anti-CRE (Millipore, 69050-3, diluted 1:1000); Anti-TBX1 (Abcam ...