Labshake search

401 - 450 of 1533 citations for 3 5 Chloro 1H benzimidazol 2 yl propan 1 amine dihydrochloride since 2020

• Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington’s Disease

  Amy McCaughey-Chapman, et al., bioRxiv - Neuroscience 2024

  Quote: ... and PSD-95 (1:250, Synaptic Systems). The species-appropriate Alexa Fluor™ secondary antibodies (1:500 ...
• Effect of the daily exposure of 1.7 GHz LTE electromagnetic field in early fetal brain development using a human brain organoid model of the cerebral cortex

  Gyu Yeon Park, et al., bioRxiv - Developmental Biology 2024

  Quote: ... MAP2 (1:500; Synaptic Systems, Germany #106002), SYN1 (1:500 ...
• Effect of the daily exposure of 1.7 GHz LTE electromagnetic field in early fetal brain development using a human brain organoid model of the cerebral cortex

  Gyu Yeon Park, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SYN1 (1:500; Synaptic Systems, Germany #188004), Alexa Fluor Rabbit 488 (Invitrogen ...
• Amyloid-β can activate JNK signalling via WNT-5A/ROR2 to reduce synapse formation in Alzheimer’s disease

  Kevin Fang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Synaptophysin 1 (Synaptic Systems, 101 002), anti-β-3-tubulin (Synaptic Systems ...
• Extremely potent Human Monoclonal Antibodies for the Prophylaxis and Therapy of Tetanus

  Marco Pirazzini, et al., bioRxiv - Pathology 2021

  Quote: ... Neutralization was determined by monitoring the cleavage of VAMP-2 with a primary antibody specific for the intact form of the protein (Synaptic System 104 211) and an antibody specific for SNAP-25 (clone SMI81 Biolegend ...
• Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival

  Charles H. Danan, et al., bioRxiv - Cell Biology 2023

  Quote: ... RIP-seq was performed according to the “Refined RIP-seq” protocol for low input material (40) with the following specifications: 2 µg anti-m6A antibody (Synaptic Systems 202 003) was conjugated to magnetic beads and incubated with 6 ug total RNA that was previously fragmented to ∼300 nt fragments with 10 mM ZnCl2 in 10 mM Tris-HCl for 4 minutes at 70°C (5% of fragmented RNA was set aside as input) ...
• The juxtamembrane linker of synaptotagmin 1 regulates Ca²⁺ binding via liquid-liquid phase separation

  Nikunj Mehta, et al., bioRxiv - Neuroscience 2023

  Quote: ... followed by immunostaining (anti-syt1, 105 103, Synaptic Systems, 1:500; anti-syp, 101 004, Synaptic Systems, 1:500) at 4°C overnight ...
• Location analysis of presynaptically active and silent synapses in single-cultured hippocampal neurons

  Otoya Kitaoka, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-vesicular glutamate transporter 1 (anti-vGLUT1) at 1:2,000 (rabbit polyclonal, affinity-purified, Synaptic Systems, Göttingen, Germany). Secondary antibodies were applied using Alexa Fluor 488 or 594 (Thermo Fisher Scientific ...
• Oxytocin neurons mediates the effect of social isolation via the VTA circuits

  Stefano Musardo, et al., bioRxiv - Neuroscience 2021

  Quote: ... cells were incubated with primary antibody (Oxytocin, 1/10000 dilution, Immunostar #20068, or cFOS 1/5000 dilution, Synaptic Systems #226008) diluted in PBS-BSA-TX (0.5% BSA and 0.3% Triton X-100 ...
• An early cortical progenitor-specific mechanism regulates thalamocortical innervation

  Suranjana Pal, et al., bioRxiv - Neuroscience 2020

  Quote: ... Mouse anti-RFP (1:200; Allele Biotech, catalog #ABP-MAB-RT008, rabbit anti-Cplx3 (1: 200; Synaptic Systems, catalog#122302). The sections were then washed in 0.1 M PB ...
• Optical TrkB activation in Parvalbumin interneurons regulates intrinsic states to orchestrate cortical plasticity

  Frederike Winkel, et al., bioRxiv - Neuroscience 2020

  Quote: ... the sections were incubated with the following antibodies: 1) guinea pig anti-parvalbumin (1:1000) (#195004, Synaptic Systems, Göttingen, Germany), 2 ...
• CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats

  Kylie A Huckleberry, et al., bioRxiv - Neuroscience 2023

  Quote: ... Sections were then incubated with primary antibody (mouse anti-CB1R 1:500, Synaptic Systems, 258 011, 289C1, Lot 1-4) in blocking solution on shaker overnight at 4°C ...
• Distinct nano-structures support a multifunctional role of actin at presynapses

  Dominic Bingham, et al., bioRxiv - Neuroscience 2022

  Quote: ... guinea pig anti-VGLUT (135 304, 1:500, Synaptics Systems) and rabbit anti-VGAT (131 003, 1:1000, Synaptic Systems). After rinses in ICC ...
• Sleep-dependent engram reactivation during hippocampal memory consolidation is associated with subregion-specific biosynthetic changes

  Lijing Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... and either goat-anti-tdTomato 1:600 (SICGEN; AB8181-200) or guinea pig-anti-Arc 1:500 (Synaptic Systems; 156004). Sections were then incubated with secondary antibodies at 4°C for 2 days in CF™ 633 Anti-Rabbit IgG H+L 1:1000 (Sigma-Aldrich ...
• SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions

  Anna Kádková, et al., bioRxiv - Neuroscience 2023

  Quote: ... Incubation in primary antibodies (a-SNAP25: mouse, 1:10000, SYSY 111011, Synaptic Systems; a-VCP: mouse, 1:2000, ab11433, Abcam) was performed overnight with 70 rpm shaking at 4 °C ...
• Dendritic degeneration and altered synaptic innervation of a central auditory neuron during age-related hearing loss

  Meijian Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... using primary antibodies against vesicular glutamate transporter 1 (VGluT1) (polyclonal Guinea pig anti-vGluT1; Cat#: 135304, Synaptic Systems, 1:500) and calretinin (rabbit ant-CR ...
• Non-canonical adrenergic neuromodulation of motoneuron intrinsic excitability through β-receptors in wild-type and ALS mice

  Stefano Antonucci, et al., bioRxiv - Neuroscience 2024

  Quote: ... sections were incubated in BB for 2h and with primary antibodies (anti-misfSOD1 1:1000, Médimabs MM-0070; anti-VAChT 1:500, Synaptic Systems, 139105 ...
• The Neural Blueprint of Stress Susceptibility: Brain-wide neuronal activity associated with the consequences of stress

  Bart C.J. Dirven, et al., bioRxiv - Neuroscience 2024

  Quote: ... and then incubated with primary antibodies (rabbit anti-RFP, 1:750, 600-401-379, Rockland; guinea pig anti-cFos, 1:2.500, 226004, Synaptic Systems; in antibody buffer ...
• Astrocytic striatal GABA transporter activity governs dopamine release and shows maladaptive downregulation in early parkinsonism

  Bradley M. Roberts, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-GAT1 (1:1,000, Synaptic Systems, 274102); rabbit anti-GAT3 (1:250 ...
• Perineuronal nets affect memory and learning after synapse withdrawal

  Jiri Ruzicka, et al., bioRxiv - Neuroscience 2021

  Quote: ... and vGAT (1:200, inh. Presynaptic, Synaptic Systems) were used ...
• Synaptic Activity-Dependent Changes in the Hippocampal Palmitoylome

  Glory Nasseri, et al., bioRxiv - Neuroscience 2021

  Quote: ... Syntaxin-1a (1:500; Synaptic Systems 132 002), VGLUT1 (1:1,000 ...
• Disrupting ATXN1 Nuclear Localization in a Knock-in SCA1 Mouse Model Improves a Spectrum of SCA1-Like Phenotypes and their Brain Region Associated Transcriptomic Profiles

  Hillary P. Handler, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:250 anti-guinea pig CALB1 (Synaptic Systems)) at 4°C ...
• Presynaptically silent synapses are modulated by the density of surrounding astrocytes

  Kohei Oyabu, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:2,000 (rabbit polyclonal, affinity-purified, Synaptic Systems). Appropriate secondary antibodies conjugated to Alexa Fluor 488 (anti-guinea pig ...
• Synaptic and intrinsic mechanisms impair reticular thalamus and thalamocortical neuron function in a Dravet syndrome mouse model

  Carleigh Studtmann, et al., bioRxiv - Neuroscience 2021

  Quote: ... and gephyrin (1:200; Synaptic Systems; 147-011). Sections were incubated with Alexa 555-conjugated anti-mouse IgG1 and Alexa 488-conjugated anti-rabbit secondary antibodies (ThermoFisher) ...
• Violet light modulates the central nervous system to regulate memory and mood

  Nobunari Sasaki, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Brn3a (411003, Synaptic Systems, 1:1000); rabbit anti-Melanopsin (AB-N39 ...
• Brain injury environment critically influences the connectivity of transplanted neurons

  S. Grade, et al., bioRxiv - Neuroscience 2021

  Quote: ... guinea pig anti-Satb2 (1:250; Synaptic Systems), mouse anti-GFAP (1:1000 ...
• Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function

  Qianyi Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-hEAAT1 (1:1000, Synaptic Systems). Secondary antibody used was Alexa Fluor 647-conjugated goat anti-rabbit (1:1000 ...
• Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in SCA1

  Kimberly Luttik, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-vGlut2 (Synaptic Systems, 135402, 1:500), rabbit anti-β-Catenin (Sigma ...
• Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degeneration

  Julian Wolf, et al., bioRxiv - Genomics 2021

  Quote: ... 1:500 for AIF1 (234-013, Synaptic Systems) and 1:200 for Collagen IV (AB769 ...
• Parabrachial neuron types categorically encode thermoregulation variables during heat defense

  Wen Z. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cfos (Synaptic systems, #226003, 1: 10000), guinea pig anti-cfos (Synaptic systems ...
• Activation of group II metabotropic receptors attenuates cortical E-I imbalance in a 15q13.3 microdeletion mouse model

  Marzieh Funk, et al., bioRxiv - Neuroscience 2020

  Quote: ... VGluT1 (Guinea pig, Synaptic Systems, 135304, 1:500). After a washing step with PBS for 45 minutes ...
• Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain

  Johannes Knabbe, et al., bioRxiv - Neuroscience 2020

  Quote: ... α-Chromogranin A (Chr-A, 1:500; Synaptic Systems). Alexa Fluor antibodies (1:500 ...
• Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

  Shataakshi Dube, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Gephyrin (Synaptic Systems 147011, 1:300), and mouse anti-Rac1 (BD Biosciences 610650 ...
• Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

  Vanessa M. Doulames, et al., bioRxiv - Neuroscience 2021

  Quote: ... VGlut1 (135 304, 1:150 dilution; Synaptic Systems) and VGlut2 (135 404 ...
• Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals

  Charles Ducrot, et al., bioRxiv - Neuroscience 2020

  Quote: ... guinea pig anti-bassoon (1:1000, Synaptic Systems), rabbit anti-RIM-1/2 (1:1000 ...
• Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatum

  Peter H. Chipman, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-GFAP (1:1000, Synaptic Systems #173011), rabbit anti-GFAP (1:500 ...
• Synapse development is regulated by microglial THIK-1 K⁺ channels

  Pablo Izquierdo, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Iba1 (1:500, Synaptic Systems 234003), mouse anti-vGluT1 (1:300 ...
• Synapse development is regulated by microglial THIK-1 K⁺ channels

  Pablo Izquierdo, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Homer1 (1:300, Synaptic Systems 160002), rabbit anti-Iba1 (1:500 ...
• Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

  Carlo Brighi, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-VGLUT1 (135303 Synaptic Systems, 1:250), rabbit anti-PSD95 (3450 Cell Signaling ...
• Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

  Shataakshi Dube, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Homer1 (Synaptic Systems 160002, 1:500), guinea pig anti-Synapsin1 (Synaptic Systems 106104 ...
• Dscam gene triplication causes neocortical overinhibition in Down syndrome

  H Liu, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-VGAT (131 004; 1:1,000; Synaptic System), rabbit anti-GRASP1 (1:2,000 ...
• Extracellular matrix supports excitation-inhibition balance in neuronal networks by stabilizing inhibitory synapses

  Egor Dzyubenko, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-GABAB (1:1000, 322102, Synaptic Systems) and mouse anti-synaptotagmin-1 (1:1000 ...
• Vinculin mediated axon growth requires interaction with actin but not talin

  Pranay Mandal, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Tau (#314002, 1:1000, Synaptic Systems, Germany). The following secondary antibodies from Invitrogen Inc. ...
• Astroglia in lateral habenula is essential for antidepressant efficacy of light

  Sarah Delcourte, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-NeuN (Guinea Pig, 1:500, Synaptic systems) and anti RFP (Rabbit ...
• Discrete TrkB-expressing neurons of the dorsomedial hypothalamus regulate feeding and thermogenesis

  Jessica Houtz, Guey-Ying Liao, Baoji Xu, bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cFos (1:10,000 Synaptic System #226003) in 1% horse serum ...
• Axonal TAU sorting requires the C-terminus of TAU but is independent of ANKG and TRIM46 enrichment at the AIS

  M. Bell, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TRIM46 (1:500, #377003, Synaptic Systems). Nuclei were stained with NucBlue™ (1 drop/ml ...
• A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down Scaling

  Chi-Hong Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... guinea pig anti-Shank3 (1:1000, Synaptic Systems), guinea pig or rabbit anti-VGluT1 (1:1000 ...
• The Amyloid Precursor Protein is a conserved Wnt receptor

  Tengyuan Liu, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-rab5 (1:100, Synaptic Systems, 108011), mouse anti-Golgin-97 (1:100 ...
• Temporal origin of mouse claustrum and development of its cortical projections

  Anna Hoerder-Suabedissen, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Cplx3 (1:1000, Synaptic Systems, 122302), rat anti-MBP (1:500 ...
• A role for thalamic projection GABAergic neurons in circadian responses to light

  O. Brock, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-vGAT (1:2000, 131013, Synaptic systems), goat anti-ChAT (1:1000 ...