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451 - 500 of 1520 citations for 3 3 2 3 Dimethyl indol 1 yl 2 hydroxy propylamino propan 1 ol since 2020

• Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders

  Yongjin Park, et al., bioRxiv - Genomics 2021

  Quote: ... and anti-Iba1 Antibody (1:500; Synaptic Systems; Cat ...
• AAV-delivery of diacylglycerol kinase kappa achieves long-term rescue of Fmr1-KO mouse model deficits of fragile X syndrome

  Karima Habbas, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GFAP (1:500, 173002, Synaptic system), overnight at 4 °C ...
• Elucidation of Amyloid-Beta’s Gambit in Oligomerization: Truncated Aβ fragments of residues Aβ1-23, Aβ1-24 and Aβ1-25 rapidly seed to form SDS-stable, LMW Aβ oligomers that impair synaptic plasticity

  Beatriz Gil, et al., bioRxiv - Neuroscience 2022

  Quote: ... and PSD95 (Synaptic Systems 124 014; 1:50) and detected with anti-mouse IgG alexa fluor 594 ...
• Generalized fear following acute stress is caused by change in co-transmitter identity of serotonergic neurons

  Hui-quan Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit-anti-VGLUT3 (Synaptic Systems, 135203, 1:500), guinea pig-anti-VGLUT3 (Synaptic Systems ...
• Human mutations in SLITRK3 implicated in GABAergic synapse development in mice

  Stephanie Efthymiou, et al., bioRxiv - Genetics 2022

  Quote: ... and anti-vGAT (1:500, 131004, Synaptic Systems) in 1x PBS solutions overnight at 4°C ...
• Regulation of parvalbumin interneuron plasticity by neuropeptide-encoding genes

  Martijn Selten, et al., bioRxiv - Neuroscience 2023

  Quote: ... Parvalbumin anti-Chicken (1:250, Synaptic Systems, 195006), Parvalbumin anti-Mouse (1:3000 ...
• Differential modification of the C-terminal tails of different α-tubulins and their importance for microtubule function in vivo

  Mengjing Bao, et al., bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-1D5 (1:150, Synaptic System) at 4°C overnight ...
• Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

  Yuqi Gui, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit against Synapsin1 (1:1,000; Synaptic Systems #163103), rabbit against SNAP25 (1:2,000 ...
• A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences

  Amy J. Gleichman, et al., bioRxiv - Neuroscience 2023

  Quote: ... NeuN (1:1000, chicken, Synaptic Systems #266 006); CD31 (1:100 ...
• Synaptic mechanisms for associative learning in the cerebellar nuclei

  Robin Broersen, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea-pig anti-VGLUT1 (1:500, Synaptic Systems), rabbit anti-VGLUT1 (1:1000 ...
• Synaptic mechanisms for associative learning in the cerebellar nuclei

  Robin Broersen, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea pig anti-VGLUT2 (1:1000, Synaptic Systems) and mouse anti-gephyrin (1:500 ...
• Synaptic mechanisms for associative learning in the cerebellar nuclei

  Robin Broersen, et al., bioRxiv - Neuroscience 2023

  Quote: ... and mouse anti-gephyrin (1:500, Synaptic Systems). After washing ...
• Heterogeneous complement and microglia activation mediates stress-induced synapse loss

  Breeanne M. Soteros, et al., bioRxiv - Neuroscience 2023

  Quote: ... IgG1 (1:500, Synaptic systems, cat#: 147 021), rabbit anti-cFOS (1:500 ...
• Engram cell connectivity as a mechanism for information encoding and memory function

  Clara Ortega-de San Luis, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-VGLUT1 (1:400, Synaptic Systems, 135-304), anti-VGAT (1:1000 ...
• GLUT1 ablation in astrocytes paradoxically improves central and peripheral glucose metabolism via enhanced insulin-stimulated ATP release

  Carlos G. Ardanaz, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-c-Fos (1:500, Synaptic Systems, 226004), anti-GFAP (1:1000 ...
• Astrocytes in the retinorecipient superior colliculus display unique cellular and structural properties

  Josien Visser, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-VGLuT1 (mouse, 1:200, Synaptic Systems, #135511) and anti-Homer-1 (rabbit ...
• Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

  Michelle M. Frank, et al., bioRxiv - Neuroscience 2022

  Quote: ... Guinea Pig anti-Parvalbumin (Synaptic Systems, 1:1,000). The following day ...
• NPAS4 supports drug-cue associations and relapse-like behavior through regulation of the cell type-specific activation balance in the nucleus accumbens

  Brandon W. Hughes, et al., bioRxiv - Neuroscience 2022

  Quote: ... or anti-FOS (1:1000, rabbit, Synaptic Systems) in blocking buffer at room temperature for 2 hr ...
• Rejection of inappropriate synaptic partners mediated by transcellular FLRT2-UNC5 signaling

  Cameron L. Prigge, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-gephyrin 1:700 (147021, Synaptic Systems); rabbit anti-GFP 1:500 (AB3080P ...
• Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain

  Anda M. Chirila, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti-gephyrin (1:1000; Synaptic Systems). The tissue was washed in HS PBSt ...
• Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain

  Gülçin Vardar, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse monoclonal anti-STX1A (1:10.000; Synaptic Systems), mouse monoclonal anti-SNAP25 (1:10.000 ...
• Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain

  Gülçin Vardar, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse monoclonal anti-SNAP25 (1:10.000; Synaptic Systems), and rabbit polyclonal anti-STX3 (1:1000 ...
• Activity-dependent lateral inhibition signals for synaptic competition

  Satoshi Fujimoto, et al., bioRxiv - Neuroscience 2022

  Quote: ... Mouse anti-VAMP2 (1:500, Synaptic Systems, 104211) and mouse anti-FLAG (1:500 ...
• Single cell transcriptomic profiling of tauopathy in a novel 3D neuron-astrocyte coculture model

  Hannah Drew Rickner, et al., bioRxiv - Neuroscience 2022

  Quote: ... VGLUT1 (Synaptic Systems, Cat#135-203, 1:100), GAD67 (Thermo Fisher Scientific ...
• Engineered Adhesion Molecules Drive Synapse Organization

  W. Dylan Hale, T. C. Südhof, R. L. Huganir, bioRxiv - Neuroscience 2022

  Quote: ... Guinea Pig anti-vGluT1 (Synaptic Systems 1:1000); Mouse anti-GAD65 [GAD6] (Abcam 1:1000) ...
• Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions

  Paul Jongseo Lee, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and MAP2 (Synaptic Systems, 188 006, 1:1000), coverslips were incubated with the primary antibody diluted in 10% normal goat serum overnight at 4°C ...
• The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release relies on the integrity of the C-terminal half of the SNARE domain of Syntaxin-1A

  Andrea Salazar-Lázaro, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse monoclonal anti-STX1A (1:1000; Synaptic Systems) and rabbit polyclonal anti-STX2 (1:1000 ...
• The Diversified Astrocyte Developmental Programs are Modulated by Primary Ciliary Signaling

  Lizheng Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... Vglut1 (Guinea pig, 1:1000; Synaptic Systems GmbH). AlexaFluor 488 ...
• Functional activation of dorsal striatum astrocytes improves movement deficits in hemi-parkinsonian mice

  Wesley R. Evans, et al., bioRxiv - Neuroscience 2024

  Quote: ... or mouse anti-S100b 1:1000 (Synaptic Systems) was placed in the blocking solution and left overnight at room temperature on an orbital shaker ...
• Single residues in the complexin N-terminus exhibit distinct phenotypes in synaptic vesicle fusion

  Estelle Toulme, et al., bioRxiv - Neuroscience 2024

  Quote: ... and VGlut1 (1:4000; Synaptic Systems; #135 304). Subsequently ...
• Extinction Training Suppresses Activity of Fear Memory Ensembles Across the Hippocampus and Alters Transcriptomes of Fear-Encoding Cells

  Alfredo Zuniga, et al., bioRxiv - Neuroscience 2024

  Quote: ... or 1:2000 rabbit anti-Arc (Synaptic Systems) primary antibodies ...
• Cell-type specific effects of Fusarium mycotoxins on primary neuronal and astroglial cells

  Viktória Szentgyörgyi, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-GFAP (chicken, 1:1000, Synaptic System, Germany) and anti-Iba1 (goat ...
• Brain-wide neuronal circuit connectome of human glioblastoma

  Yusha Sun, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-VAChT (Synaptic Systems, 139103, 1:500), mouse anti-TPH2 (Thomas Scientific ...
• Revisiting the potency of Tbx2 expression in transforming outer hair cells into inner hair cells at multiple ages in vivo

  Zhenghong Bi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-vGlut3 (rabbit, 1:500; 135203, Synaptic Systems), anti-GFP (chicken ...
• Trafficking of Connexin36 (Cx36) in the early secretory pathway

  Stephan Tetenborg, et al., bioRxiv - Biochemistry 2024

  Quote: ... Sec22b 1:250 (186004; Synaptic Systems, Goettingen, Germany), Syntaxin5 1:500 (110 053 ...
• Engram cell connectivity as a mechanism for information encoding and memory function

  Clara Ortega-de San Luis, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-GPHN (1:500, Synaptic Systems, 147 008) and anti-RFP (1:1000 ...
• Engram cell connectivity as a mechanism for information encoding and memory function

  Clara Ortega-de San Luis, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-VGAT (1:1000, Synaptic Systems, 131 005), anti-GPHN (1:500 ...
• Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance

  Na Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Homer 1 (Synaptic Systems Cat# 160003, RRID: AB_887730), CSPα (Chemicon ...
• TRPM2-CaMKII signaling drives excessive GABAergic synaptic inhibition following ischemia

  Amelia M. Burch, et al., bioRxiv - Neuroscience 2023

  Quote: ... and VGAT (1:1000 Synaptic Systems Rabbit – 131003) antibodies in permeabilization solution overnight at 4°C on a rocker ...
• Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

  Artemis Koumoundourou, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea pig anti-Homer1 (1:250; Synaptic Systems), rabbit anti-C1ql2 (1:1000 ...
• Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

  Artemis Koumoundourou, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-ZnT3 (1:200; Synaptic Systems). All fluorescent secondary antibodies were purchased from Jackson ImmunoResearch and used at 1:500 dilution ...
• Impairment of hippocampal astrocyte-mediated striatal dopamine release and locomotion in Alzheimer’s disease

  Benjamin B. Tournier, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Neun (1/500, guinea pig; Synaptic System), and anti-FOS (1/500 ...
• Uncoupling of synaptic loss from amyloid burden by an Alzheimer’s disease protective variant of PLCγ2

  Ryan J. Bevan, et al., bioRxiv - Neuroscience 2023

  Quote: ... chicken anti-Iba1 (1:250, Synaptic Systems, 234009), rat anti-CD68 (1:500 ...
• Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

  Artemis Koumoundourou, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea pig anti-vGlut1 (1:250; Synaptic Systems), chicken anti-GFP (1:2000 ...
• Cockayne syndrome patient iPSC-derived brain organoids and neurospheres show early transcriptional dysregulation of biological processes associated with brain development and metabolism

  Leon-Phillip Szepanowski, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-MAP2 (Synaptic Systems, 1:500 #188011), guinea pig anti-NeuN (1:500 ...
• The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release relies on the integrity of the C-terminal half of the SNARE domain of Syntaxin-1A

  Andrea Salazar-Lázaro, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit polyclonal anti-STX3A (1:10,000; Synaptic Systems), rabbit polyclonal anti-Munc18-1 (1:10,000 ...
• The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release relies on the integrity of the C-terminal half of the SNARE domain of Syntaxin-1A

  Andrea Salazar-Lázaro, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit polyclonal anti-STX2 (1:10,000; Synaptic Systems), rabbit polyclonal anti-STX3A (1:10,000 ...
• Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice

  David V.C. Brito, et al., bioRxiv - Neuroscience 2023

  Quote: ... or CB1R (1:500, Synaptic systems #258 008) diluted in PBS containing 2% normal goat serum and 0.3% Triton X-100 at 4 °C overnight ...
• Noradrenergic signaling controls Alzheimer’s disease pathology via activation of microglial β2 adrenergic receptors

  L. Le, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea pig anti-GFAP (1:3,000, Synaptic Systems), mouse anti-TH (1:500 ...
• Presynaptic Rac1 in the hippocampus selectively regulates working memory

  Jaebin Kim, et al., bioRxiv - Animal Behavior and Cognition 2024

  Quote: ... mouse-anti-RFP (1:500, Synaptic Systems 409011), rabbit-anti-Homer1 (1:500 ...