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1 - 50 of 870 citations for Fumarase from porcine heart since 2020

• Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy

  Dipak Panigrahy, et al., bioRxiv - Cell Biology 2024

  Quote: ... Western blots were performed on lysates of hearts from WT and Dsg2mut/mut mice using methods described in previous studies.17,18 ELISA assays were performed on extracts of hearts from WT and Dsg2mut/mut mice using kits and protocols from Cayman Chemicals as described in previous studies.17,19 qPCR was used to measure expression of genes related to the ER-stress response and innate immune signaling as described in previous studies.18
• Impaired S-nitrosylation of Cx43 prevents arrhythmogenicity and myocardial injury upon cardiac stress in Duchenne Muscular Dystrophy

  Manuel F. Muñoz, et al., bioRxiv - Physiology 2024

  Quote: ... Heart samples underwent incubation with Biotin-HPDP (#16459, Cayman Chemicals) and sodium L-ascorbate (#11140 ...
• Coordinated Tbx3 / Tbx5 transcriptional control of the adult ventricular conduction system

  Ozanna Burnicka-Turek, et al., bioRxiv - Developmental Biology 2024

  Quote: The Langendorff Perfused heart was electromechanically uncoupled by 15 μM of blebbistatin (Cayman Chemicals 13186) perfusion ...
• Insulin Resistance Mediates Crosstalk between Skeletal Muscle and the Heart to Prevent Cardiac Dysfunction

  Dandan Jia, et al., bioRxiv - Cell Biology 2020

  Quote: ... Lipid peroxidation production in heart tissues was analyzed by measuring changes in malondialdehyde (MDA) using a TBARS kit (Cayman Chemical Company, Cat No.10009055) according to the manufacturer’s instruction ...
• Artemisia extracts Differ from Artemisinin Effects on Human Hepatic CYP450s 2B6 and 3A4 in vitro

  Ndeye F. Kane, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... from Cayman Chemical: artemisinin (11816) ...
• A dual MTOR/NAD+ acting gerotherapy

  Jinmei Li, et al., bioRxiv - Genomics 2023

  Quote: ... from Cayman Chemical; Bolt 4-12% Bis-Tris gels ...
• Type III interferons disrupt the lung epithelial barrier upon viral recognition

  Achille Broggi, et al., bioRxiv - Immunology 2020

  Quote: ... Diphtheria toxin (unnicked) from Corynebacterium diphtheriae was purchased from Cayman Chemical. Anti-Ly6G antibody ...
• CTPS1 inhibition synergizes with replication stress signaling inhibition in MYC-amplified Group 3 medulloblastoma

  Matthew R Hathaway, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Brequinar was procured from SelleckChem (S6626) and Lometrexol from Cayman Chemical Company (18049) ...
• Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization

  Melanie Balbach, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... nigericin from Cayman Chemical, ionomycin from Tocris ...
• Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen

  Sirle Saul, et al., bioRxiv - Microbiology 2021

  Quote: ... Small molecule inhibitors were purchased from MedchemExpress or from Cayman Chemical except for Ac-Leu-Leu-Nle-CHO (BML-P120 ...
• PIEZO1-mediated mechanosensing governs NK cell killing efficiency and infiltration in three-dimensional matrices

  Archana K. Yanamandra, et al., bioRxiv - Immunology 2024

  Quote: ... blebbistatin from Cayman Chemical, Yoda-1 from Tocris ...
• A co-ordinated transcriptional programme in the maternal liver supplies LC-PUFAs to the conceptus using phospholipids

  Risha Amarsi, et al., bioRxiv - Physiology 2023

  Quote: ... and from Cayman Chemicals (Bertin Bioreagent ...
• TWO CLASSES OF MYOSIN INHIBITORS, BLEBBISTATIN AND MAVACAMTEN, STABILIZE β-CARDIAC MYOSIN IN DIFFERENT STRUCTURAL AND FUNCTIONAL STATES

  Sampath K. Gollapudi, et al., bioRxiv - Biochemistry 2020

  Quote: ... whereas blebbistatin and para-nitroblebbistatin were purchased from external sources (blebbistatin from Fisher Scientific, IL, and para-nitroblebbistatin from Cayman Chemical Company, MI). Concentrated stocks (20 mM ...
• A2E induces the transactivation of RARs, PPARs and RXRs and its effects are counteracted by norbixin in retinal pigment epithelium cells in vitro

  Valérie Fontaine, et al., bioRxiv - Cell Biology 2020

  Quote: ... GW9578 was from Cayman Chemical Company (Ann Arbor ...
• Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity

  Bartholomew P. Roland, et al., bioRxiv - Cell Biology 2020

  Quote: ... Myriocin was from Cayman Chemicals while aureobasidin A was from Takara Bio.
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... ABC294640 (10587) from Cayman chemical and the DES1 inhibitor (B-0027 ...
• Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets

  Kimber L. Boekell, et al., bioRxiv - Cell Biology 2022

  Quote: ... and U46619 from Cayman Chemical. Antibodies were from the following sources ...
• Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo

  Gonzalo P. Solis, et al., bioRxiv - Cell Biology 2022

  Quote: ... DDD85646 (13839) from Cayman Chemical, 2-bromopalmitate (sc-251714 ...
• Loss of LGR5 through plasticity or gene ablation is associated with therapy resistance and enhanced MET-STAT3 signaling in colorectal cancer cells

  Tressie A. Posey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and XAV939 from Cayman Chemical. The plasmid encoding myc-LGR5 was generated previously (9) ...
• Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

  Chia-Chuan D. Cho, et al., bioRxiv - Biochemistry 2021

  Quote: ... was purchased from Cayman Chemicals.
• The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, are potent BACH1 inhibitors

  Laura Casares, et al., bioRxiv - Cell Biology 2021

  Quote: ... Leptomycin B from Cayman Chemicals, MLN4924 and Selinexor (KPT-330 ...
• Tonic endocannabinoid signaling supports sleep through development in both sexes

  Sheneé C. Martin, et al., bioRxiv - Animal Behavior and Cognition 2021

  Quote: ... were purchased from Cayman Chemicals. Drugs were dissolved in DMSO and then prepared into vehicle solution (5%DMSO ...
• Bepridil is potent against SARS-CoV-2 In Vitro

  Erol C. Vatansever, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... and rimonabant from Cayman Chemicals, ebastine and itraconazole from Alfa Aesar ...
• Chronic exposure of ErbB TKIs inhibits DRA expression and activity through an ERK/Elk-1/CREB/AP-1 dependent pathway

  Hong Yang, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Reagents were from Cayman Chemical: nigericin (#11437) ...
• Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

  Chia-Chuan D. Cho, et al., bioRxiv - Biochemistry 2021

  Quote: ... were purchased from Cayman Chemicals. The PLpro substrate ...
• SARS-CoV-2 immune complex triggers human monocyte necroptosis

  Leonardo Duarte Santos, et al., bioRxiv - Immunology 2022

  Quote: ... Piceatannol was from Cayman Chemical. Histopaque-1077and NEC-1s were purchased from Sigma-Aldrich ...
• 12/15-Lipoxygenases mediate neuropathic-like pain hypersensitivity in female mice

  B Brown, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... were obtained from Cayman Chemical: Prostaglandin E2 (PGE2 ...
• Regulation of RNA methylation by therapy treatment, promotes tumor survival

  Syed IA Bukhari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... were obtained from Cayman Chemicals and used as described ...
• Ca²⁺ and cAMP open differentially dilating synaptic fusion pores

  Dinara Bulgari, et al., bioRxiv - Neuroscience 2023

  Quote: ... H-89 from Cayman Chemicals and St-Ht31 from Fisher Scientific.
• Readiness of nociceptor cell bodies to generate spontaneous activity results from background activity of diverse ion channels and high input resistance

  Jinbin Tian, et al., bioRxiv - Neuroscience 2023

  Quote: ... AMG-9810 from Cayman Chemical Company ...
• An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

  Grace Y. Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... SAM (13956) from Cayman Chemical; Effectene transfection reagent from Qiagen ...
• Calcium transients trigger switch-like discharge of prostaglandin E₂ in an extracellular signal-regulated kinase-dependent manner

  Tetsuya Watabe, et al., bioRxiv - Cell Biology 2023

  Quote: ... was purchased from Cayman Chemical. Flurbiprofen axetil was purchased from KAKEN Pharmaceutical.
• Discovery of anthelmintic small molecules in the Medicines for Malaria Venture’s COVID and Global Health Priority Boxes using an infrared-based assay for Caenorhabditis elegans motility

  Yujie Uli Sun, Lawrence J. Liu, Conor R. Caffrey, bioRxiv - Microbiology 2023

  Quote: ... Milbemectin was from Cayman Chemical, and moxidectin ...
• Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states

  Brian MacTavish, et al., bioRxiv - Biophysics 2024

  Quote: ... were purchased from Cayman Chemical. Details for the new compounds reported in this study can be found in Supplementary File 1 ...
• Antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitro

  Tomofumi Nakamura, et al., bioRxiv - Microbiology 2024

  Quote: ... and MCFG from Cayman Chemical USA ...
• Presynaptic filopodia form kinapses and modulate membrane mechanics for synchronous neurotransmission and seizure generation

  Akanksha Jain, et al., bioRxiv - Neuroscience 2024

  Quote: ... carbamazepine (18467) from Cayman Chemical; Neurobasal (21103-049) ...
• TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells

  Shuvasree SenGupta, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Doramapimod from Cayman Chemicals (10460), human CXCL-8 antibody from R&D systems (MAB208-100) ...
• Real-time imaging of Arc/Arg3.1 transcription ex vivo reveals input-specific immediate early gene dynamics

  Pablo J. Lituma, et al., bioRxiv - Neuroscience 2021

  Quote: ... NBQX was obtained from Cayman Chemical Company ...
• Targeting CoV-2 Spike RBD and ACE-2 Interaction with Flavonoids of Anatolian Propolis by in silico and in vitro Studies in terms of possible COVID-19 therapeutics

  Halil Ibrahim Guler, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Daidzein from Cayman Chemical (Michigan, USA) and Ferric tripyridyl triazine (Fe-III-TPTZ) ...
• Early events in reovirus infection influence induction of innate immune response

  Andrew T. Abad, Pranav Danthi, bioRxiv - Microbiology 2022

  Quote: Dynasore was purchased from Cayman Chemical Company ...
• Differential regulation of prelimbic and thalamic transmission to the basolateral amygdala by acetylcholine receptors

  Sarah C. Tryon, et al., bioRxiv - Neuroscience 2021

  Quote: ... AM630 was purchased from Cayman Chemical Company (Ann Arbor ...
• Disease-associated mutations in TRPM3 render the channel overactive via two distinct mechanisms

  Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, bioRxiv - Neuroscience 2020

  Quote: ... ionomycin and PregS from Cayman Chemicals. For measurements at 37 °C the MEM medium used to culture the cells was replaced with the measurement solution preheated to 37 °C ...
• Dismantling and rebuilding the trisulfide cofactor demonstrates its essential role in human sulfide quinone oxidoreductase

  Aaron P. Landry, et al., bioRxiv - Biochemistry 2020

  Quote: ... DHLA was purchased from Cayman Chemical Company (Ann Arbor ...
• KDM6A mediated expression of the long noncoding RNA DINO causes TP53 tumor suppressor stabilization in Human Papillomavirus type 16 E7 expressing cells

  Surendra Sharma, Karl Munger, bioRxiv - Cancer Biology 2020

  Quote: ... Metformin was purchased from Cayman Chemicals. Doxycycline and metformin were dissolved in PBS and freshly prepared for each use.
• A simplified cell-based assay to identify coronavirus 3CL protease inhibitors

  Samuel J. Resnick, et al., bioRxiv - Microbiology 2020

  Quote: ... Tipranavir was purchased from Cayman Chemical. MAC5576 ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... GW4869 was purchased from Cayman Chemicals. Phalloidin was purchased from Molecular Probes ...
• Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and ERK signaling

  Carlene Moore, et al., bioRxiv - Physiology 2021

  Quote: ... Parthenolide was purchased from Cayman Chemicals. GSK205 ...
• Evaluation of 19 antiviral drugs against SARS-CoV-2 Infection

  Shufeng Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... Favilavir was obtained from Cayman Chemical and chloromethylketone was from Enzo Life Sciences.
• Aneuploidy-driven genome instability triggers resistance to chemotherapy

  Marica Rosaria Ippolito, et al., bioRxiv - Cancer Biology 2020

  Quote: Reversine was obtained from Cayman Chemical and used at a working concentration of 0,25 μM or 0,5 μM ...
• HIF1α inhibition by dual targeting of CDK4/6 and HSP90 reduces cancer cell viability including Rb-deficient cells

  Shuai Zhao, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Onalespib was purchased from Cayman Chemical Company ...