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251 - 300 of 410 citations for 2 3 Cyclohexenyl Ethyltrimethoxysilane since 2020

• A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation

  Xiao Qin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ICG-001 (CBP/β-Catenin inhibitor, 2 µM, Cayman Chemical 16257), Dasatinib (SRC inhibitor ...
• Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus

  Kerry McGowen, et al., bioRxiv - Microbiology 2024

  Quote: ... + water with 2 µg mL−1 linezolid-d3 (25038, Cayman Chemicals) and 2 µg mL−1 verapamil (V105 ...
• Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk

  Sarah Staudt, et al., bioRxiv - Immunology 2024

  Quote: ... cells were incubated with fluorescent glucose analog 2-NBDG (Cayman Chemicals) for 20 min at 37 °C ...
• Chromosomal curing drives prophage evolution and bacterial epidemiology

  Min Jung Kwun, et al., bioRxiv - Microbiology 2024

  Quote: ... 2 μl 0.5 μg ml-1 mitomycin C (Cayman Chemical Company); 2μl 9% aqueous hydrogen peroxide solution (LCM Group) ...
• Endocannabinoid regulation of inward rectifier potassium (Kir) channels

  Sultan Mayar, et al., bioRxiv - Biophysics 2024

  Quote: ... namely Arachidoyl Ethanolamide (AEA) and 2-Palmitoyl Glycerol (PAG) (Cayman Chemical), was characterized by SPR ...
• The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles

  Verena M. Straub, et al., bioRxiv - Neuroscience 2024

  Quote: ... VDM11 (10006731) and OMDM-2 (10179) were purchased from Cayman Chemical. WOBE437 (76 ...
• Development of a Low-Cost System for Simultaneous Longitudinal Biological Imaging

  Victoria T. Ly, et al., bioRxiv - Bioengineering 2021

  Quote: ... we supplemented the aggregates with WNT inhibitor (IWR1-ε, 3 µM, Cayman Chemical, 13659, Days 1-10) and TGF-βinhibitor (SB431542 ...
• Characterization of TR-107, a Novel Chemical Activator of the Human Mitochondrial Protease ClpP

  Emily M. J. Fennell, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: Caspase-3/7 activity was analyzed using a fluorescent peptide substrate (Ac-DEVD-AMC, Cayman Chemical, 14986) as previously described(46) ...
• Human METTL7B Encodes an Alkyl Thiol Methyltransferase that Methylates Hydrogen Sulfide

  Benjamin J. Maldonato, Rheem A. Totah, bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... 1,2-Dimyristoyl-sn-glycero-3-PG (DMPG) and mertansine were obtained from Cayman Chemical (Ann Arbor, MI). The active metabolite of prasugrel was a gift from Dr ...
• Comprehensive benchmarking of single cell RNA sequencing technologies for characterizing cellular perturbation

  Verboom Karen, et al., bioRxiv - Molecular Biology 2020

  Quote: ... the cells were treated with either 8 μM of nutlin-3 (Cayman Chemicals, 10004372, dissolved in ethanol) or vehicle (ethanol) ...
• Investigation of adenosine A1 receptor mediated β-arrestin 2 recruitment using a split-luciferase assay

  Luisa Saecker, Hanns Häberlein, Sebastian Franken, bioRxiv - Pharmacology and Toxicology 2023

  Quote: The test ligands were obtained from the following suppliers: N6-Cyclopentyladenosine (CPA; Cayman Chemicals, 41552-82-3), 5’-N-Ethylcarboxam-idoadenosine (NECA ...
• Cell Type-Agnostic Optical Perturbation Screening Using Nuclear In-Situ Sequencing (NIS-Seq)

  Caroline I. Fandrey, et al., bioRxiv - Genomics 2024

  Quote: ... cells were selected and induced with 3 μg/ml Puromycin and 1 μg/ml Doxycycline (Cayman Chemicals). Cells were split 1:3 when reaching confluency ...
• Identification and targeting of microbial putrescine acetylation in bloodstream infections

  Jared R. Mayers, et al., bioRxiv - Microbiology 2023

  Quote: ... mice received 3 days of 20 µm filter-sterilized drinking water ± 250 mg/L anhydrotetracycline (Cayman Chemicals) in red-tinted bottles (Ancare ...
• METTL7A and METTL7B are responsible for S-thiol methyl transferase activity in liver

  Drake A. Russell, et al., bioRxiv - Biochemistry 2022

  Quote: ... mertansine and 1,2-Dimyristoyl-sn-glycero-3-PG (DMPG) were obtained from Cayman Chemicals (Ann Arbor, Mi); 7α-thiospironolactone was produced in-house from spironolactone using a previously published method (Agusti et al. ...
• E-cadherin mediated Apical Membrane Initiation Site localisation

  Xuan Liang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 2i/LIF (1 mM MEK inhibitor PD0325901, 13034, Cayman Chemical; 3 mM GSK3 inhibitor CHIR99021, 13122, Cayman Chemical; and 10 ng/ml leukemia inhibitory factor ...
• Oct4 primarily controls enhancer activity rather than accessibility

  Le Xiong, et al., bioRxiv - Genomics 2021

  Quote: ... 0.5x B27 supplement (Life Technology, 12587-010), 0.5x N2 supplement (Gibco, AM9759, 3 µM CHIR99021 (Cayman Chemicals, 13122), 1 µM PD0325901 (Biomol ...
• Bioorthogonal labeling enables in situ fluorescence imaging of expressed gas vesicle nanostructures

  Erik Schrunk, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... then applying 250 μL of a 3 μM working solution of FlAsH-EDT2 (Cayman Chemical, Ann Arbor, MI) in HBSS to each well ...
• Host PGD₂ acting on DP2 receptor attenuates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis

  Giovanna N. Pezzella-Ferreira, et al., bioRxiv - Immunology 2023

  Quote: Isolated eosinophils (3 x 106 cells/mL) were co-incubated or not with CAY10471 (200 nM; Cayman Chemicals) and then stimulated for 1 h (37 °C ...
• Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells

  Shyamili Goutham, et al., bioRxiv - Cancer Biology 2024

  Quote: OVCAR-3 and COV362 cells at 70-80% confluence were treated with IC50 dose carboplatin (Cayman Chemicals - 13112) for 2 hours ...
• The role of the cannabinoid system in fear memory and extinction in male and female mice

  Ikumi Mizuno, et al., bioRxiv - Neuroscience 2021

  Quote: WIN55,212-2 (0.075, 0.75 mg/kg) (Cayman Chemicals, Ann Arbor, MI, USA) was dissolved in saline with 10% dimethyl sulfoxide (DMSO ...
• Central inhibition of P2Y₁₂R differentially regulates survival and neuronal loss in MPTP-induced Parkinsonism in mice

  András Iring, et al., bioRxiv - Neuroscience 2021

  Quote: ... Y-27632 were obtained from Cayman Chemicals (Cat. No. 129830-38-2). PSB 0739 were from Tocris Bio (Cat ...
• SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes

  Lilian Gomes de Oliveira, et al., bioRxiv - Immunology 2021

  Quote: ... 5mM (2-DG, Cat. Number.17149; Cayman Chemicals, Ann Arbor, Michigan, USA) and Etomoxir ...
• Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy

  Kunal Sikder, et al., bioRxiv - Cell Biology 2023

  Quote: ... the cells were treated with 2 μM thapsigargin (Cayman Chemical cat# 10522), 20 μM brefeldin A (Cayman Chemical cat# 11861) ...
• PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

  Nina Đukić, et al., bioRxiv - Cell Biology 2023

  Quote: ... Olaparib (Cayman Chemical; 1 μM for U2OS; 2 μM for 293T cells), 1 μM PARGi PDD00017273 (Sigma ...
• APC and P53 mutations synergize to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer

  Yuhua Tian, et al., bioRxiv - Cancer Biology 2022

  Quote: ... overlaid with colonic differentiation medium supplemented with 2 uM Thiazovivin (Cayman Chemical) and allowed to recover for 48 hours ...
• Two successive oligomeric Munc13 assemblies scaffold vesicle docking and SNARE assembly to support neurotransmitter release

  Manindra Bera, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2-Dihexanoyl-sn-glycerol was purchased from Cayman Chemicals (Ann Arbor, MI). TCEP HCl were purchased from Thermo Fisher (Waltham ...
• Working memory performance predicts, but does not reduce, cocaine- and cannabinoid-seeking in adult male rats

  Sierra J. Stringfield, et al., bioRxiv - Neuroscience 2024

  Quote: The synthetic cannabinoid WIN55,212-2 mesylate (WIN, Cayman Chemicals, Ann Arbor, MI) was dissolved in Tween 80 and 0.9% sterile saline ...
• Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression

  Nadine Tuechler, et al., bioRxiv - Systems Biology 2024

  Quote: ... and 500 μM L-ascorbic acid 2-phosphate (Cayman Chemical Company 16457). TGF-β treated samples received the same medium with an additional 10 ng/ml of recombinant human TGF-β1 (R&D systems 240-B-010) ...
• Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio

  Katherine R. Ferrick, et al., bioRxiv - Cell Biology 2024

  Quote: ... 200 nM MK2206 (Cayman Chemical Cat#11593, CAS#1032350-13-2, AKTi), 100 nM Torin2 (Cayman Chemical Cat#14185 ...
• Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity

  Waqas Younis, et al., bioRxiv - Biochemistry 2024

  Quote: ... a redox-sensitive fluorescent probe (Cayman chemical company, cat # 104821-25-2). Briefly ...
• CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production

  Miriam Doepner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 3-O-methyl-L-DOPA hydrate (20737) and Entacapone (14153) were purchased from Cayman Chemicals (Ann Arbor, MI, USA). NB-55 ...
• Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D

  Geetika Aggarwal, et al., bioRxiv - Biochemistry 2020

  Quote: ... N-octyl-β-D-glucoside (NOG) and 7-diethylamino-3-(4’-maleimidylphenyl)-4-methylcoumarin were obtained from Cayman Chemicals. Standard protein molecular weight marker was purchased from Invitrogen ...
• FOXO regulates neuromuscular junction homeostasis during Drosophila aging

  Allison Birnbaum, Kai Chang, Hua Bai, bioRxiv - Molecular Biology 2020

  Quote: 3-day post eclosion flies were placed on food containing less than 0.1% ethanol and 200uM Mifepristone (Cayman Chemical) or no other additive for 3 days ...
• Mechanoreceptors initiate innate immunity in response to microbial infections

  Giulia Stucchi, et al., bioRxiv - Immunology 2024

  Quote: ... we collected the supernatant 3 hours after stimulation to measure LTB4 (Leukotriene B4 Express ELISA Kit 500003, Cayman Chemicals) or TNF-α release (88-7324-88 ...
• Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

  Bryan J. Song, et al., bioRxiv - Neuroscience 2024

  Quote: The drugs used in our study include: D1R antagonist (SKF 83566 hydrobromide, Cayman Chemical #29480; 3 mg kg−1), D2R antagonist (eticlopride hydrochloride ...
• TGFβR Inhibition Represses TGF-β1 Initiated Keratin-7 Expression in Human Salivary Gland Progenitor Cells

  Eric W. Fowler, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 2 µM of A83-01 (9001799; Cayman Chemical Company, Ann Arbor, MI) as single factors or in combination when appropriate ...
• WNT11 is a novel ligand for ROR2 in human breast cancer

  Kerstin Menck, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cells were either pre-incubated for two hours with IWP-2 (Cayman Chemical), WNT-C59 (Tocris) ...
• Inhibition of GFAT1 in lung cancer cells destabilizes PD-L1 protein and improves immune response

  Wenshu Chen, Bryanna Saxton, Steven A. Belinsky, bioRxiv - Cancer Biology 2020

  Quote: ... CB-839 (1439399-58-2) was obtained from Cayman Chemical (Ann Arbor, MI). VPS34 inhibitor (532628 ...
• Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

  Chih-Wei Chu, et al., bioRxiv - Immunology 2023

  Quote: 2-Fluoro-peracetyl-fucose (2FPF) was purchased from Cayman Chemicals (Ann Arbor, MI) and dissolved in DMSO (Cell Signaling Technologies ...
• Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

  Michelle C.D. Bridi, et al., bioRxiv - Neuroscience 2023

  Quote: ... and the bath contained only 10μM (+)-WIN55,212-2 (Cayman Chemical, Ann Arbor, MI), 10μM SR 141716A (Abmole ...
• Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery

  R Venkat Kalyana Sundaram, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2-Dihexanoyl-sn-glycerol (DHG) was purchased from Cayman Chemicals (Ann Arbor, MI). Alexa Fluor 568/647 – Maleimide and TCEP HCl were purchased from Thermo Fisher (Waltham ...
• γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids

  Junxue Dong, et al., bioRxiv - Immunology 2023

  Quote: ... 2 μM TGF-β receptor kinase Inhibitor IV (A83-01, Cayman Chemicals, Cay9001799), 10 μM ROCK inhibitor (Y-27632 ...
• Expression Ratios of the Anti-Apoptotic BCL2 Family Members Dictate the Selective Addiction of KSHV-Transformed Primary Effusion Lymphoma Cell Lines to MCL1

  Daniel Dunham, et al., bioRxiv - Microbiology 2022

  Quote: ... At designated time points (2 days for puromycin (Cayman Chemicals, Ann Arbor, MI); 3 days for MCL1i (MedChemExpress ...
• Liver-specific LXR inhibition represses reverse cholesterol transport in cholesterol-fed mice

  Takafumi Nishida, et al., bioRxiv - Physiology 2023

  Quote: ... anti-rabbit anti-sterol regulatory element-binding protein-2 (SREBP2, Cayman chemical, MI), anti PCSK9 (Cayman chemical) ...
• Alternative paths to immune activation: the role of costimulatory risk genes for polygenic inflammatory disease in T helper cells

  Alexandru-Ioan Voda, et al., bioRxiv - Genomics 2023

  Quote: ... autophagy was measured after 2 hour treatment with either bafilomycin A1 (Cayman chemical) or vehicle ...
• Overactivated epithelial NF-κB disrupts lung development in human and nitrofen CDH

  Florentine Dylong, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Explants were cultured for 2 days with either 4.4mM nitrofen (Cayman Chemicals #20341) dissolved in DMSO or DMSO in medium alone (vehicle ...
• Identification of PTGR2 inhibitors as a new therapy for diabetes and obesity

  Yi-Cheng Chang, et al., bioRxiv - Physiology 2024

  Quote: ... and 0.1 μM 2-deoxy-D-Glucose (2DG) (cat. no. 14325, Cayman Chemical) for 5 min ...
• IGF-1 facilitates extinction of conditioned fear

  José A. Noriega-Prieto, et al., bioRxiv - Neuroscience 2020

  Quote: ... or the IGF-1R antagonist 7-[cis-3-(1-azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]-7H-pyrrolo[2,3-]pyrimidin-4-amine (NVP-AEW 541, 40 μM; Cayman Chemicals) plus IGF-1 were infused into the IL ...
• Targeting Chromatin Effector Pygo2 to Enhance Immunotherapy in Prostate Cancer

  Yini Zhu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... was transfected into PS and PSP cells with jetOPTIMUS (Polyplus, 101000051) followed by 10μM nutlin-3 (Cayman Chemical Company, 10004372), 500ng/ml CPT (Chem-Impex ...
• Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid

  Anika J. Friedman, et al., bioRxiv - Biochemistry 2022

  Quote: ... and 2-[(Carboxy-carbonyl)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid hydrochloride (TCS 401) from Cayman Chemical (Ann Arbor, Michigan) and Ertiprotafib from Med-Koo Biosciences ...