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201 - 250 of 698 citations for 3 4 Fluorophenyl 5 fluorobenzoic acid since 2020

• Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism

  Zander Harpel, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5-methyluridine (Cayman Chemical), 5-fluorouracil (Cayman Chemical) ...
• The rifampicin-inactivating mono-ADP-ribosyl transferase of Mycobacterium smegmatis significantly influences reactive oxygen species levels in the actively growing cells

  Sharmada Swaminath, et al., bioRxiv - Microbiology 2020

  Quote: ... 3’-(p-hydroxyphenyl) fluorescein (HPF, Cayman chemical) (42) ...
• Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

  Emiliano Hergenreder, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 3 μM of CHIR99021 (Cayman Chemical) for 24 hours ...
• Conserved and divergent features of DNA methylation in embryonic stem cell-derived neurons

  Sally Martin, et al., bioRxiv - Genomics 2020

  Quote: ... 3 µM CHIR 99021 (Cayman Chemical Company) and 0.5 µM PMA (Sigma ...
• Prevention of tau accumulation through inhibition of hnRNP R-dependent axonal Mapt mRNA localization

  Abdolhossein Zare, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 µM CHIR99021 (13122, Cayman Chemical Company) and 0.5 µM purmorphamine (PMA ...
• Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release

  Zhijia Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 3-MB-PP1 was from Cayman Chemical. KU-60019 was from Selleck Chemicals ...
• Spatial biology of Ising-like synthetic genetic networks

  Kevin Simpson, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... 3-oxohexanoyl-homoserine lactone (C6HSL, Cayman Chemicals) and 3-oxododecanoyl-homoserine lactone (C12HSL ...
• Embryonic lymphocytes contribute to a genetic form of autoimmune inflammation

  Sara Cascione, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 3 μM CHIR99021 (Cayman Chemical Company, CT99201) were added ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... 3 μg/mL tunicamycin (Tm) (Cayman Chemical) for 2h ...
• CD32 allows capturing blood cells emergence in slow motion during human embryonic development

  Rebecca Scarfò, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 3 μM CHIR99021 (Cayman Chemical Company, CT99201) were added ...
• Modulation of WNT, Activin/Nodal and MAPK Signaling Pathways Increases Arterial Hemogenic Endothelium and Hematopoietic Stem/Progenitor Cell Formation During Human iPSC Differentiation

  Yongqin Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 3 μM LY294002 (#70920, Cayman Chemicals) was added from day 3 to day 6 of differentiation unless otherwise indicated.
• PROTEOMICS OF HYPOTHERMIC ADAPTATION REVEALS THAT RBM3 ENHANCES MITOCHONDRIAL METABOLISM AND MUSCLE STEM-CELL DIFFERENTIATION

  Paulami Dey, et al., bioRxiv - Biochemistry 2023

  Quote: ... 3 uM FCCP (Cayman chemical 800364-9897), 1.5 uM of antimycin (Cayman chemicals 1397-94-0 ...
• The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores

  Matteo Burigotto, et al., bioRxiv - Cell Biology 2023

  Quote: ... 10 µM 3-MB-PP1 (Cayman Chemical). Thymidine was dissolved in water whereas all other drugs were dissolved in DMSO ...
• Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter

  Zoey A. Miller, et al., bioRxiv - Physiology 2024

  Quote: ... 3-oxo-C12HSL sourced from Cayman Chemical was also used in experiments to validate effects from different suppliers ...
• Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network

  Rebecca M. Sebastian, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 2.5 μM nutlin-3 (Cayman Chemical Company), or 1 μg/mL dox and 2.5 μM nutlin-3 ...
• Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders

  Bhanwar Lal Puniya, et al., bioRxiv - Systems Biology 2020

  Quote: We purchased alpha-difluoromethylornithine (DFMO) and eicosapentaenoic Acid (EPA) from Cayman Chemical. DFMO was resuspended in water at 50mM while EPA was already resuspended in ethanol at 826 mM ...
• Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer

  Caterina Bartolacci, et al., bioRxiv - Cancer Biology 2021

  Quote: ... we incubated them with 20 µM arachidonic acid alkyne (Cayman Chemical, 10538) in RPMI with 2% ultra-fatty acid free BSA (SIGMA ALDRICH ...
• Lipidomic profiling reveals age-dependent changes in complex plasma membrane lipids that regulate neural stem cell aging

  Xiaoai Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Single-point internal standard calibration with deuterated oleic acid (Cayman Chemical, 9000432) was used to estimate absolute concentrations for all free fatty acids.
• Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases

  Ryan R. Kawalerski, et al., bioRxiv - Cancer Biology 2022

  Quote: K17-disassembly following hyperphosphorylation was assessed using okadaic acid (OA, Cayman Chemical) and sodium orthovanadate (OV ...
• The ORP9-ORP11 dimer promotes sphingomyelin synthesis

  Birol Cabukusta, et al., bioRxiv - Cell Biology 2024

  Quote: Cells were incubated with 20µM ethanolic palmitic acid alkyne (Cayman Chemical #13266) in serum-free medium for 6 hours ...
• A microvascularized in vitro liver model for disease modeling and drug discovery

  Flavio Bonanini, et al., bioRxiv - Bioengineering 2024

  Quote: ... and BSA-Oleate Monosaturated Fatty Acid Complex (oleate, Cayman Chemical Company #29557) which are both provided at a stock concentration of 5 mM ...
• Inhibition of the extracellular matrix protein fibulin-3 reduces immunosuppressive signaling in tumor stem cells and increases macrophage activation against glioblastoma

  Somanath Kundu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and the NF-κB inhibitor caffeic acid phenetyl-ester (CAPE, Cayman Chemical). Commercially available antibodies and PCR primers used in this study are listed in Supplementary Tables I and II ...
• Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression

  Nadine Tuechler, et al., bioRxiv - Systems Biology 2024

  Quote: ... and 500 μM L-ascorbic acid 2-phosphate (Cayman Chemical Company 16457). TGF-β treated samples received the same medium with an additional 10 ng/ml of recombinant human TGF-β1 (R&D systems 240-B-010) ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cis-7-hexadecenoic acid (cis-7-C16:1, Cayman Chemical, Cat# 10007290), cis-8-octadecenoic acid (cis-8-C18:1 ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 14(Z)-eicosenoic acid (cis-14-C20:1, Cayman Chemical, Cat# 10009375), cis-vaccenic acid (cis-11-C18:1 ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 10(Z)-pentadecenoic acid (cis-10-C15:1, Cayman Chemical, Cat# 22362), 10(E)-pentadecenoic acid (trans-10-C15:1 ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and trans-vaccenic acid (trans-11-C18:1, Cayman Chemical, Cat# 15301).
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 10(E)-pentadecenoic acid (trans-10-C15:1, Cayman Chemical, Cat# 22467), cis-11-eicosenoic acid/11(Z ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cis-6-hexadecenoic acid (cis-6-C16:1, Cayman Chemical, Cat# 9001845), cis-7-hexadecenoic acid (cis-7-C16:1 ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cis-10-heptadecenoic acid (cis-10-C17:1, Cayman Chemical, Cat# 19748), trans-10-heptadecenoic acid (trans-10-C17:1 ...
• Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems

  Vivian S. Park, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cis-8-octadecenoic acid (cis-8-C18:1, Cayman Chemical, Cat# 27447), cis-10-heptadecenoic acid (cis-10-C17:1 ...
• Contrasting effects of reduced phosphatidylcholine synthesis in absence of seipin: embryonic lethality goes down while lipid droplets get even larger

  Jinglin Zhu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and d8-20:4 (Cayman Chemicals) as internal standards ...
• ASK1 promotes inflammation in senescence and aging

  Takeru Odawara, Shota Yamauchi, Hidenori Ichijo, bioRxiv - Cell Biology 2023

  Quote: ... 4-hydroxy Tamoxifen (Cayman Chemical, 17308) at a final concentration of 200 nM was added to IMR-90 ER-KRAS cells ...
• Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restriction

  Qi Qu, et al., bioRxiv - Physiology 2023

  Quote: ... and d8-20:4 (Cayman Chemicals). For neutral lipids (TAGs and DAGs) ...
• Succinate mediates inflammation-induced adrenocortical dysfunction

  Ivona Mateska, et al., bioRxiv - Immunology 2022

  Quote: ... 4-OI (125 μM; Cayman Chemical), IL-1β(20 ng/ml ...
• Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii

  Christopher Jonkergouw, et al., bioRxiv - Biochemistry 2023

  Quote: ... N-(3-Hydroxy-7-cis-tetradecanoyl)-L-HSL (>95%) (3-OH-C14:1) was used as received from Cayman Chemical. Organic solvents were purchased from Sigma-Aldrich and VWR ...
• Tissue- and sex-specific DNA damage tracks aging in rodents and humans

  Axel Guilbaud, et al., bioRxiv - Biochemistry 2022

  Quote: ... 5’-Ethynyl-2’-deoxycytidine and 5’-chloro-2’- deoxycytidine were obtained from Cayman Chemical Company (Ann Arbor ...
• CTCF and cohesin promote focal detachment of DNA from the nuclear lamina

  Tom van Schaik, et al., bioRxiv - Molecular Biology 2021

  Quote: ... GSK-3β inhibitor CHIR99021 (3 μM; Cayman Chemical) and 1-thioglycerol (1.5 × 10−4 M ...
• The role of the cannabinoid system in fear memory and extinction in male and female mice

  Ikumi Mizuno, et al., bioRxiv - Neuroscience 2021

  Quote: ... URB597 (0.3, 1, 3 mg/kg) (Cayman Chemicals) was dissolved in saline with 10% DMSO ...
• Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells

  Gahyang Cho, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 3 μM CHIR99021 (Cayman Chemical, Ann Arbor, MI), and 2 mM LiCl (Sigma ...
• Fatty acid desaturation and lipoxygenase pathways support trained immunity

  Anaísa V. Ferreira, et al., bioRxiv - Immunology 2023

  Quote: ... 0.3 or 3 µM 15-HETE (Cayman Chemical), 0.1 ...
• Genetic mapping identifies Homer1 as a developmental modifier of attention

  Zachary Gershon, et al., bioRxiv - Neuroscience 2024

  Quote: ... and DAPI (Cayman Chemical, Cat#28718-90-3). For immunohistochemistry staining ...
• Predicting efficacy of immunotherapy in mice with triple negative breast cancer using a cholesterol PET radiotracer

  Nicholas G. Ciavattone, et al., bioRxiv - Immunology 2023

  Quote: ... and 3-dodecanoyl-NBD Cholesterol (Cayman Chemicals, #13220) for in vivo and in vitro experiments respectively.
• Pioneer activity distinguishes activating from non-activating pluripotency transcription factor binding sites

  Michela Maresca, et al., bioRxiv - Molecular Biology 2022

  Quote: ... GSK3-β inhibitor CHIR99021 (3 µM, Cayman Chemical) and 1-Thioglycerol (1.5×10-4 M ...
• Oncogene-like addiction to aneuploidy in human cancers

  Vishruth Girish, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 3-deazauridine (Cayman Chemical; cat. no. 23125) in both A2780 ...
• Rapid High-Throughput Method for Investigating Physiological Regulation of Neutrophil Extracellular Trap Formation

  Kieran Zukas, et al., bioRxiv - Immunology 2024

  Quote: ... Caspase-3/7 Inhibitor I (Cayman Chemical, 14464), or vehicle were added to the wells ...
• PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation

  Aflah Hanafiah, et al., bioRxiv - Genomics 2024

  Quote: ... and 3 μM Chir99021 (CH) (Cayman Chemical, 13122). The MEFs were allowed to settle and attach to the plates’ surface before plating ESCs on them ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... UK5099 (5 μM, Cayman Chemical), CPI-613 (200 μM ...
• Formate Promotes Invasion and Metastasis by Activating Fatty Acid Synthesis and Matrix Metalloproteinases

  Catherine Delbrouck, et al., bioRxiv - Cancer Biology 2023

  Quote: ... C75 (Cayman Chemicals: 10005270-5) and TVB-2640 (Selleckchem ...
• A Coronaviral Pore-Replicase Complex Drives RNA Synthesis in Double Membrane Vesicles

  Anan Chen, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5’-ethynyl-uridine (Cayman Chemical), actinomycin D (Cayman Chemical) ...