Labshake search

351 - 400 of 569 citations for 6 Phenyl 1H imidazo 1 2 b pyrazole since 2019

• Lipid accumulation promotes scission of caveolae

  Madlen Hubert, et al., bioRxiv - Biochemistry 2020

  Quote: ... D-lactosyl-ß-1,1’ N-palmitoyl-D-erythro-sphingosine [LacCer(d18:1/16:0)] and Lyso-Lactosylceramide (Lyso-LacCer) were purchased from Avanti Polar Lipids Inc ...
• The Ebola virus VP40 matrix undergoes endosomal disassembly essential for membrane fusion

  Sophie L. Winter, et al., bioRxiv - Microbiology 2022

  Quote: ... (d18:1 with N-acylated 14:0, 19:0, 27:0, semi-synthesized or GlcCer d18:1/17:0, Avanti Polar Lipids), 5 pmol lactosylceramide (Hex2Cer ...
• Utilizing a nanobody recruitment approach for assessing serine palmitoyltransferase activity in ER sub-compartments of yeast

  Bianca M. Esch, et al., bioRxiv - Biochemistry 2023

  Quote: ... PS 17:0-14:1, PE 17:0-20:4, PC 17:0-20:4, PI 17:0-20:4, LPE 17:1; Avanti Polar Lipids) was added before lipid extraction ...
• Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro

  Vera Vysochinskaya, et al., bioRxiv - Molecular Biology 2023

  Quote: ... [27] in a mixture of CHCl3–CH3OH (1:1 vol.) was added to a solution of 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE, Avanti Polar Lipids, USA) in CHCl3 at a molar ratio of 1:3 and gently stirred ...
• Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8⁺ T cells

  Elisa Matas-Rico, et al., bioRxiv - Cancer Biology 2021

  Quote: ... LPA(1-oleoyl) was obtained from Avanti Polar Lipids. Human ATX was produced in HEK293 Flip-in cells and purified as previously described (Salgado-Polo et al. ...
• Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P₂ by a phosphotransferase

  Glenn F. W. Walpole, et al., bioRxiv - Cell Biology 2021

  Quote: ... 16:0-18:1 PS (POPS, Avanti Polar Lipids Inc ...
• Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model

  Jian Hang Lam, et al., bioRxiv - Immunology 2022

  Quote: ... using a 1 ml mini-extruder (Avanti Polar Lipids) to get monodispersed ACM-antigen vesicles ...
• The glycolipid GlcCer is recruited into the viral envelope to promote phenuivirus binding to host cells

  Zina M. Uckeley, et al., bioRxiv - Microbiology 2022

  Quote: ... or GlcCer (d18:1/17:0, Avanti Polar Lipids)) ...
• Oncogenic memory underlying minimal residual disease in breast cancer

  Ksenija Radic Shechter, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 10 pmol lyso-phosphatidylcholine (17:1, Avanti Polar Lipids), 50 pmol cardiolipin (14:1/14:1/14:1/15:1 ...
• Linking medicinal cannabis to autotaxin-lysophosphatic acid signaling

  Mathias C. Eymery, et al., bioRxiv - Biochemistry 2022

  Quote: ... and LPA 18:1 (#857130C) from Avanti Polar Lipids. Choline quantification kits (#40007 ...
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... lysophosphatidylcholine (LPC 18:1-d7, Avanti Polar Lipids, 791643C), phosphatidylglycerol (PG 15:0/18:1-d7 ...
• Structure of an open K_ATP channel reveals tandem PIP₂ binding sites mediating the Kir6.2 and SUR1 regulatory interface

  Camden M. Driggers, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 1 mg/mL brain PIP2 (Avanti Polar Lipids), and incubated at 4°C for 30 minutes before increasing the volume 10x in the same buffer without added lipids but including the detergent digitonin at a final concentration of 0.5% ...
• Absence of cardiolipin from the outer leaflet of a mitochondrial inner membrane mimic restricts Opa1-mediated fusion

  Yifan Ge, et al., bioRxiv - Biophysics 2021

  Quote: ... L-α-phoshphatidylinositol (liver PI) and 1’,3’-bis[1,2-dioleoyl-sn-glycero-3-phospho]-glycerol (18:1 cardiolipin) from Avanti Polar Lipids (AL, USA). Inter-leaflet asymmetric bilayers were assembled in a layer-by-layer manner ...
• Establishment of the Meyer-Overton correlation in an artificial membrane without protein

  Atsushi Matsumoto, Yukifumi Uesono, bioRxiv - Biophysics 2023

  Quote: ... DSPG), and 1,2-dioleoyl-sn-glycero-3-[phosphor-rac-(1-glycerol)] (18:1-PG, DOPG) were purchased from Avanti Polar Lipids (Alabaster, AL). Cholesterol (CHOL ...
• Genome sequences of equine influenza A subtype H3N8 viruses by long read sequencing and functional characterization of the PB1-F2 virulence factor of A/equine/Paris/1/2018

  Lena Kleij, et al., bioRxiv - Microbiology 2023

  Quote: ... and (18:1) cardiolipin 1’,3’-bis[1,2-dioleoyl-sn-glycero-3-phospho]-glycerol (DOCL) (840044) were purchased from Avanti Polar Lipids (Alabaster, AL, USA). (16:0-18:1 ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Sphingomyelin(18:1/18:1-d9) and C11 TopFluor Sphingomyelin (N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosylphosphorylcholine) (Avanti Polar Lipids 791649 and 810265P). Azithromycin (MedChemExpress ...
• Structure and reconstitution of a MCU-EMRE mitochondrial Ca²⁺ uniporter complex

  Chongyuan Wang, et al., bioRxiv - Biochemistry 2020

  Quote: ... and 0.01 mg/mL 18:1 cardiolipin (Avanti Polar Lipids)) ...
• Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma

  Chad VanSant-Webb, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1% Splash Lipidomix Mass Spec Standard (Avanti Polar Lipids, 330707), and 1% Deuterated Ceramide Lipidomix Mass Spec Standard (Avanti Polar Lipids ...
• Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

  Le Zheng, et al., bioRxiv - Biochemistry 2023

  Quote: ... using D-erythrosphingosine (d18:1) (Cat# 860490P, Avanti Polar Lipids) as the standard ...
• Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

  Delfina Larrea, et al., bioRxiv - Molecular Biology 2022

  Quote: ... in conjunction with referencing of appropriate internal standards: ceramide d18:1/17:0 and sphingomyelin d18:1/12:0 (Avanti Polar Lipids, Alabaster, AL, USA). Values were represented as mole fraction with respect to total lipid (% molarity) ...
• Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

  Carmen Bekeova, et al., bioRxiv - Biochemistry 2023

  Quote: ... The tissue was added to low retention Eppendorf tube prepared with 0.6 mL 80% methanol (MeOH) and 20 µL SPLASH® LIPIDOMIX (diluted 1:1 with methanol from original #330707 Avanti solution) (Avanti Polar Lipids, Alablaster, AL) and kept in dry ice ...
• Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6)

  Charline Ogier, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 20 µL of lipidomics internal standard mix (1:1, SPLASH® LIPIDOMIX #330707: Ceramide/Sphingoid Internal Standard Mixture I #LM6002, both from Avanti Polar Lipids, Alablaster, AL) and kept in dry ice ...
• Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

  Marion Régnier, et al., bioRxiv - Pathology 2019

  Quote: ... SM d18:1/12:0) were purchased from Avanti Polar Lipids.
• Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

  Yifan Ge, et al., bioRxiv - Biophysics 2019

  Quote: ... 0.1 mg/ml 18:1 cardiolipin (Avanti Polar Lipids, AL, USA) and protease inhibitors and stirred at 4 °C for 1 hr ...
• Designing Biological Micro-Sensors with Chiral Nematic Liquid Crystal Droplets

  Lawrence W. Honaker, et al., bioRxiv - Bioengineering 2021

  Quote: ... 25 mg·ml-1 in chloroform) were sourced from Avanti Polar Lipids. Kdo2-Lipid A (di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt) ...
• Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P₂ by a phosphotransferase

  Glenn F. W. Walpole, et al., bioRxiv - Cell Biology 2021

  Quote: ... 16:0-18:1 PC (POPC, Avanti Polar Lipids Inc. 850457C); 16:0-18:1 PS (POPS ...
• Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1

  Stijn van Dorp, et al., bioRxiv - Biophysics 2021

  Quote: ... biotinylated lipids (18:1 Biotinyl Cap PE, Avanti Polar Lipids #870273C) were mixed with egg-PC lipids (Avanti Polar Lipids #840051C ...
• The composition and function of Enterococcus faecalis membrane vesicles

  Irina Afonina, et al., bioRxiv - Microbiology 2021

  Quote: ... monoglucosyl-diacylglycerol (MGDAG 34:1) (Avanti polar lipids, Alabaster, AL, USA) and were run alongside the samples (Table S2).
• Nanoscale Organization of FasL on DNA Origami as a Versatile Platform to Tune Apoptosis Signaling in Cells

  Ricarda M. L. Berger, et al., bioRxiv - Biophysics 2020

  Quote: 18:1 (Δ9-cis) DOPC was purchased from Avanti Polar Lipids, Alabaster ...
• Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

  Ruilin Tian, et al., bioRxiv - Genomics 2021

  Quote: ... and PI(15:0/18:1□d7) (EquiSPLASH, Avanti Polar Lipids), and finally 4 mL MTBE ...
• Tracer-based lipidomics identifies novel disease-specific biomarkers in mitochondrial β-oxidation disorders

  Marit Schwantje, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 50 μM D9-C18:1 (Avanti Polar Lipids, Cat. No 861809O) and 25 μmol/L L-carnitine (Sigma-Aldrich ...
• Selective endocytic uptake of targeted liposomes occurs within a narrow range of liposome diameter

  Grant Ashby, et al., bioRxiv - Bioengineering 2023

  Quote: ... or 20 mol% 18:1 Biotinyl Cap PE (Avanti Polar Lipids) were added to the wells at a 1 μM total lipid concentration ...
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... phosphatidylcholine (PC 15:0/18:1-d7, Avanti Polar Lipids, 791637C), and phosphatidylethanolamine (PE 15:0/18:1-d7 ...
• Single-Cell Epitope-Transcriptomics Reveal Lung Stromal and Immune Cell Response Kinetics to Nanoparticle-delivered RIG-I and TLR4 Agonists

  M. Cole Keenum, et al., bioRxiv - Bioengineering 2022

  Quote: ... MPLA PHAD® (1 μg/mg PLGA, Avanti Polar Lipids, #699800P) was dissolved in DCM prior to emulsification ...
• Glutathione supports lipid abundance in vivo

  Gloria Asantewaa, et al., bioRxiv - Biochemistry 2023

  Quote: ... and SPLASH LIPIDOMIX (1:1000, Avanti Polar Lipids Inc., Cat# 330707). After sonicating (1400 rpm ...
• Structural basis of membrane targeting and coatomer assembly by human GBP1

  Tanja Kuhm, et al., bioRxiv - Biophysics 2023

  Quote: 1 mg of brain polar lipid extract (BPLE, Avanti Polar Lipids) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC ...
• p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

  Marion Régnier, et al., bioRxiv - Cell Biology 2024

  Quote: ... SM d18:1/12:0) were purchased from Avanti Polar Lipids. Lipid extraction Lipids were extracted from the liver (1 mg ...
• Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma

  Chad VanSant-Webb, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 1% Splash Lipidomix Mass Spec Standard (Avanti Polar Lipids 330707) was added to the homogenized tissue.
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... diacylglycerol (DAG 15:0/18:1-d7, Avanti Polar Lipids, 791647C), ceramide (Cer d18:1-d7/15:0 ...
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... phosphatidylglycerol (PG 15:0/18:1-d7, Avanti Polar Lipids, 791640C), phosphatidylcholine (PC 15:0/18:1-d7 ...
• Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2

  Lea C. Neelsen, et al., bioRxiv - Biophysics 2023

  Quote: ... and oleoyl-CoA (LC-CoA 18:1) (Avanti Polar Lipids, USA) were prepared as stocks (1 - 100 mM ...
• A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

  Eva Pyrihová, et al., bioRxiv - Biochemistry 2023

  Quote: Tetraoleoyl cardiolipin (18:1) powder was purchased from Avanti Polar Lipids. Lipids were solubilized in 10% (w/v ...
• A practical guide to time-resolved fluorescence microscopy and spectroscopy

  Benjamin S. Clark, et al., bioRxiv - Biophysics 2024

  Quote: ... A solution of 1% biotinyl cap-phosphoethanolamine (Avanti Polar Lipids, 870277P) in Egg PC (Avanti Polar Lipids ...
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... ceramide (Cer d18:1-d7/15:0, Avanti Polar Lipids, 860681), lysophosphatidylcholine (LPC 18:1-d7 ...
• Synthetic control of actin polymerization and symmetry breaking in active protocells

  Shiva Razavi, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... All lipids (Supplementary Table 1) were purchased from Avanti Polar Lipids. Hexadecane (H6703 ...
• VISION — an open-source software for automated multi-dimensional image analysis of cellular biophysics

  Florian Weber, et al., bioRxiv - Biophysics 2024

  Quote: ... and DGS-NTA(Ni) (18:1, Avanti Polar Lipids, cat# 790404C). For normal GUVs ...
• CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation

  Philippos Demetriou, et al., bioRxiv - Immunology 2019

  Quote: ... CapBio 18:1 Biotinyl Cap PE (Stratech, Avanti Polar Lipids, 870282C-AVL), CapBio-lipids ...
• Lipid binding by N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA

  Ivana Malcova, et al., bioRxiv - Microbiology 2020

  Quote: ... phosphatidylinositol (PI 16:0-18:1; cat.no.850142P, Avanti Polar Lipids, USA) or phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 18:1-18:1 ...
• Lipid binding by N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA

  Ivana Malcova, et al., bioRxiv - Microbiology 2020

  Quote: ... phosphatidylserine (PS 16:0-18:1; cat.no.840034P, Avanti Polar Lipids, USA), phosphatidylinositol (PI 16:0-18:1 ...
• PHGDH supports liver ceramide synthesis and sustains lipid homeostasis

  Yun Pyo Kang, et al., bioRxiv - Biochemistry 2019

  Quote: ... C12-doxCer [Cer(m18:1/12:0)] (860455P-1mg, Avanti Polar Lipids), and C12-dihydro-doxCer [Cer(m18:0/12:0)] (860481P-1mg ...