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401 - 450 of 912 citations for 8' Bromo 2' 3' dihydro 1'h spiro cyclopropane 1 4' isoquinoline since 2020

• The Mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs

  Sara Cioccolo, et al., bioRxiv - Biophysics 2024

  Quote: ... #791639), Phosphatidylglycerol (15:0-18:1-d7-PG, #791640) and Sphingomyelin (18:1-d9 SM, #791649) were purchased from Avanti Polar Lipids, Inc and were added to a final concentration of 10 μg/mL ...
• Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma

  Gustav Jonsson, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Internal standard mix (PE 34:0, 830456P; PS 34:0, 840028P; LPC 17:1, 855677C; SM d35:1, 860585; purchased form Avanti Polar Lipids, USA ...
• Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8⁺ T cells

  Elisa Matas-Rico, et al., bioRxiv - Cancer Biology 2021

  Quote: ... LPA(1-oleoyl) was obtained from Avanti Polar Lipids. Human ATX was produced in HEK293 Flip-in cells and purified as previously described (Salgado-Polo et al. ...
• Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P₂ by a phosphotransferase

  Glenn F. W. Walpole, et al., bioRxiv - Cell Biology 2021

  Quote: ... 16:0-18:1 PS (POPS, Avanti Polar Lipids Inc ...
• Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model

  Jian Hang Lam, et al., bioRxiv - Immunology 2022

  Quote: ... using a 1 ml mini-extruder (Avanti Polar Lipids) to get monodispersed ACM-antigen vesicles ...
• The glycolipid GlcCer is recruited into the viral envelope to promote phenuivirus binding to host cells

  Zina M. Uckeley, et al., bioRxiv - Microbiology 2022

  Quote: ... or GlcCer (d18:1/17:0, Avanti Polar Lipids)) ...
• Oncogenic memory underlying minimal residual disease in breast cancer

  Ksenija Radic Shechter, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 10 pmol lyso-phosphatidylcholine (17:1, Avanti Polar Lipids), 50 pmol cardiolipin (14:1/14:1/14:1/15:1 ...
• Linking medicinal cannabis to autotaxin-lysophosphatic acid signaling

  Mathias C. Eymery, et al., bioRxiv - Biochemistry 2022

  Quote: ... and LPA 18:1 (#857130C) from Avanti Polar Lipids. Choline quantification kits (#40007 ...
• Structure of an open K_ATP channel reveals tandem PIP₂ binding sites mediating the Kir6.2 and SUR1 regulatory interface

  Camden M. Driggers, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 1 mg/mL brain PIP2 (Avanti Polar Lipids), and incubated at 4°C for 30 minutes before increasing the volume 10x in the same buffer without added lipids but including the detergent digitonin at a final concentration of 0.5% ...
• White matter lipidome alterations in the schizophrenia brain

  Dmitry Senko, et al., bioRxiv - Neuroscience 2023

  Quote: ... lysophosphatidylcholine (LPC 18:1-d7, Avanti Polar Lipids, 791643C), phosphatidylglycerol (PG 15:0/18:1-d7 ...
• Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

  Liyu Chen, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- [amino (polyethylene glycol)-2000] (DSPE-PEG2000) (Avanti Polar Lipids) were mixed in a 9:1 molar ratio and dissolved in a small amount of chloroform (Sigma ...
• Extensive in vitro and in vivo protein translation via in situ circularized RNAs

  Aditya Kumar, et al., bioRxiv - Bioengineering 2022

  Quote: ... 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (DMG-PEG-2000) were purchased from Avanti Polar Lipids. Cholesterol was purchased from Sigma-Aldrich ...
• A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease

  Gerhard Leinenga, Wee Kiat Koh, Jürgen Götz, bioRxiv - Neuroscience 2021

  Quote: ... 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (DSPE-PEG2000) (Avanti Polar Lipids) were mixed in a 9:1 molar ratio ...
• Deep learning models for lipid-nanoparticle-based drug delivery

  Philip J Harrison, et al., bioRxiv - Cell Biology 2020

  Quote: ... the 1.2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1.2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) was obtained from Avanti Polar Lipids, 1.2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethyleneglycol)-2000] (DMPE-PEG2000 ...
• Transcriptional signature in microglia isolated from an Alzheimer’s disease mouse model treated with scanning ultrasound

  Gerhard Leinenga, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (DSPE-PEG2000) (Avanti Polar Lipids) were mixed in a 9:1 molar ratio and dissolved in chloroform (Sigma) ...
• Highly basic clusters in the HSV-1 nuclear egress complex drive membrane budding by inducing lipid ordering

  Michael K. Thorsen, et al., bioRxiv - Microbiology 2021

  Quote: Lyophilized phospholipids 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) were purchased from Avanti Polar Lipids and dissolved in chloroform at 20 mg/mL to produce individual lipid stock solutions ...
• Influenza virus membrane fusion is promoted by the endosome-resident phospholipid bis(monoacylglycero)phosphate

  Steinar Mannsverk, et al., bioRxiv - Biophysics 2022

  Quote: ... 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and biotinylated 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (biotin-DPPE) were acquired from Avanti Polar Lipids. Bovine brain disialoganglioside GD1a (Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ...
• Membrane-catalyzed aggregation of islet amyloid polypeptide is dominated by secondary nucleation

  Barend O.W. Elenbaas, et al., bioRxiv - Biophysics 2022

  Quote: 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) were acquired from Avanti Polar Lipids. Islet amyloid polypeptide (IAPP ...
• α-synuclein oligomers displace monomeric α-synuclein from lipid membranes

  Greta Šneiderienė, et al., bioRxiv - Biophysics 2024

  Quote: ... 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) were obtained from Avanti Polar Lipids, DOPE-ATTO 647 from ATTO-Tec.
• Programmable DNA shell scaffolds for directional membrane budding

  Michael T. Pinner, Hendrik Dietz, bioRxiv - Biophysics 2024

  Quote: ... 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl) (biotinylated DOPE) were obtained from Avanti Polar Lipids, and Atto488 and Atto643 modified 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE ...
• Atg15 is a vacuolar phospholipase that disintegrates organelle membranes

  Yasunori Watanabe, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine, 850375C), and DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 850725C) were obtained from Avanti Polar Lipids, Inc ...
• Towards the NMR solution Structure and the Dynamics of the C-terminal Region of APOL1 and its G1, G2 Variants with a Membrane Mimetic

  Sethu M. Madhavan, et al., bioRxiv - Biophysics 2021

  Quote: ... micelles and also using 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC)/1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bicelles (Avanti Polar Lipids, Alabaster, AL). Proteins bound to the Ni2+ column were washed with 40 column volumes (CV ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Sphingomyelin(18:1/18:1-d9) and C11 TopFluor Sphingomyelin (N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosylphosphorylcholine) (Avanti Polar Lipids 791649 and 810265P). Azithromycin (MedChemExpress ...
• A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis

  Mohammed Rizwan Babu Sait, et al., bioRxiv - Microbiology 2024

  Quote: ... 17:0 glucosyl(β) ceramide (d18:1/17:0) and 17:0 lactosyl(β) ceramide (d18:1/17:0) (all from Avanti Polar Lipids) 77 ...
• Cooperativity of myosin II motors in the non-regulated and regulated thin filaments investigated with high-speed AFM

  Oleg S. Matusovsky, et al., bioRxiv - Biophysics 2022

  Quote: ... 1,2-Dipalmitoyl-3-trimethylammonium-propane (DPTAP, Avanti Polar Lipids) and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl ...
• Surface tension-driven sorting of human perilipins on lipid droplets

  Ana Rita Dias Araujo, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 3 µg standards (manually mixed, Avanti Polar Lipids® and Sigma-Aldrich® ...
• Oxidation-induced structural changes in actin and myosin evaluated by computational simulation, machine learning modeling and high-speed AFM

  Oleg S. Matusovsky, et al., bioRxiv - Biophysics 2024

  Quote: ... 1,2-Dipalmitoyl-3-trimethylammonium-propane (DPTAP, Avanti Polar Lipids) and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl ...
• Structure and reconstitution of a MCU-EMRE mitochondrial Ca²⁺ uniporter complex

  Chongyuan Wang, et al., bioRxiv - Biochemistry 2020

  Quote: ... and 0.01 mg/mL 18:1 cardiolipin (Avanti Polar Lipids)) ...
• Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

  Le Zheng, et al., bioRxiv - Biochemistry 2023

  Quote: ... using D-erythrosphingosine (d18:1) (Cat# 860490P, Avanti Polar Lipids) as the standard ...
• Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma

  Chad VanSant-Webb, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1% Splash Lipidomix Mass Spec Standard (Avanti Polar Lipids, 330707), and 1% Deuterated Ceramide Lipidomix Mass Spec Standard (Avanti Polar Lipids ...
• A gated hydrophobic funnel within BAX binds long-chain alkenals to potentiate pro-apoptotic function

  Jesse D. Gelles, et al., bioRxiv - Cell Biology 2024

  Quote: ... and cardiolipin (18:1) (Cat. No. 710335C, Avanti Polar Lipids) were combined at a ratio of 48:28:10:10:4 (5 mg total) ...
• Modeling compound lipid homeostasis using stable isotope tracing

  Karl Wessendorf-Rodriguez, et al., bioRxiv - Cell Biology 2024

  Quote: ... SPB 18:1;O2 [D7] (Avanti Polar Lipids, Cat# 860657), and GM3-d3 18:1;O2/18:0 [D3] (Cayman Chemicals ...
• Modeling compound lipid homeostasis using stable isotope tracing

  Karl Wessendorf-Rodriguez, et al., bioRxiv - Cell Biology 2024

  Quote: ... SPB 18:1;O2 [D7] (Avanti Polar Lipids, Cat# 860657), and GM3 18:1;O2/18:0 [D3] (Cayman Chemicals ...
• Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

  Chae Min Yuk, et al., bioRxiv - Immunology 2024

  Quote: ... Synthetic C18:0/C20:4-PtdIns(4,5)P2 and C18:0/C20:4-PtdIns(3,4,5)P3 standards (Avanti Polar Lipids) were used to determine the retention time (RT) ...
• In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

  Sankalp Shukla, et al., bioRxiv - Cell Biology 2022

  Quote: The lipids 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) (DOPS) were obtained from Avanti Polar Lipids (Alabaster, AL). Lipid fluorophore 1,2 – Dioleoyl-sn-glycero-3-phosphoethanolamine labeled with Atto 647 (Atto 647 DOPE ...
• Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca²⁺-sensor ALG-2

  Sankalp Shukla, et al., bioRxiv - Biophysics 2023

  Quote: The lipids 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) (DOPS) were obtained from Avanti Polar Lipids (Alabaster, AL). Lipid fluorophore 1,2 – Dioleoyl-sn-glycero-3-phosphoethanolamine labeled with Atto 647 (Atto 647 DOPE ...
• Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

  Delfina Larrea, et al., bioRxiv - Molecular Biology 2022

  Quote: ... in conjunction with referencing of appropriate internal standards: ceramide d18:1/17:0 and sphingomyelin d18:1/12:0 (Avanti Polar Lipids, Alabaster, AL, USA). Values were represented as mole fraction with respect to total lipid (% molarity) ...
• Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

  Carmen Bekeova, et al., bioRxiv - Biochemistry 2023

  Quote: ... The tissue was added to low retention Eppendorf tube prepared with 0.6 mL 80% methanol (MeOH) and 20 µL SPLASH® LIPIDOMIX (diluted 1:1 with methanol from original #330707 Avanti solution) (Avanti Polar Lipids, Alablaster, AL) and kept in dry ice ...
• Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6)

  Charline Ogier, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 20 µL of lipidomics internal standard mix (1:1, SPLASH® LIPIDOMIX #330707: Ceramide/Sphingoid Internal Standard Mixture I #LM6002, both from Avanti Polar Lipids, Alablaster, AL) and kept in dry ice ...
• Conformational Dynamics of NSP11 Peptide of SARS-CoV-2 Under Membrane Mimetics and Different Solvent Conditions

  Kundlik Gadhave, et al., bioRxiv - Biochemistry 2021

  Quote: ... The lipids 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) were obtained from Avanti Polar Lipids (Alabaster, Alabama, U.S.A.) and prepared using the lipid extruder provided by the same manufacturer ...
• Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein

  Kundlik Gadhave, et al., bioRxiv - Biophysics 2020

  Quote: ... 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)) were purchased from Avanti Polar Lipids (Alabaster, Alabama, U.S.A.).
• SARS-CoV-2 envelope-protein corruption of homeostatic signaling mechanisms in mammalian cells

  Tobias Schulze, et al., bioRxiv - Pathology 2021

  Quote: ... DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine) and DPhPS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine) were obtained from Avanti Polar Lipids (Alabaster, AL, USA) in chloroform solution ...
• Harnessing Ultrasound-Stimulated Phase Change Contrast Agents to Improve Antibiotic Efficacy Against Methicillin-Resistant Staphylococcus aureus Biofilms

  Phillip G. Durham, et al., bioRxiv - Microbiology 2020

  Quote: ... 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000 (DSPE-PEG2000) (Avanti Polar Lipids, Alabaster, AL, USA) were dissolved in 5% glycerol ...
• The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes

  Oda C. Krokengen, et al., bioRxiv - Biochemistry 2024

  Quote: ... DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) and DOPS (1,2-dioleoyl-sn-glycero-3-phospho-L-serine) were purchased from Avanti Polar Lipids (Alabaster, Alabama, USA). Lipid stocks containing DOPC and DOPS were prepared by dissolving dry lipids in methanol (hypergrade for LC-MS ...
• A Method to sort heterogenous cell populations based on migration in 2D and 3D environments

  Aditya Arora, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 4% DOGS-NTA-Ni (Avanti Polar Lipids) were then deposited using Small Unilamellar Vesicle (SUV ...
• Designing Biological Micro-Sensors with Chiral Nematic Liquid Crystal Droplets

  Lawrence W. Honaker, et al., bioRxiv - Bioengineering 2021

  Quote: ... 25 mg·ml-1 in chloroform) were sourced from Avanti Polar Lipids. Kdo2-Lipid A (di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt) ...
• Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P₂ by a phosphotransferase

  Glenn F. W. Walpole, et al., bioRxiv - Cell Biology 2021

  Quote: ... 16:0-18:1 PC (POPC, Avanti Polar Lipids Inc. 850457C); 16:0-18:1 PS (POPS ...
• Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1

  Stijn van Dorp, et al., bioRxiv - Biophysics 2021

  Quote: ... biotinylated lipids (18:1 Biotinyl Cap PE, Avanti Polar Lipids #870273C) were mixed with egg-PC lipids (Avanti Polar Lipids #840051C ...
• The composition and function of Enterococcus faecalis membrane vesicles

  Irina Afonina, et al., bioRxiv - Microbiology 2021

  Quote: ... monoglucosyl-diacylglycerol (MGDAG 34:1) (Avanti polar lipids, Alabaster, AL, USA) and were run alongside the samples (Table S2).
• Nanoscale Organization of FasL on DNA Origami as a Versatile Platform to Tune Apoptosis Signaling in Cells

  Ricarda M. L. Berger, et al., bioRxiv - Biophysics 2020

  Quote: 18:1 (Δ9-cis) DOPC was purchased from Avanti Polar Lipids, Alabaster ...