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1 - 50 of 1353 citations for 3 Chloromethyl pyrrolidine 1 carboxylic acid benzyl ester since 2020

• Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

  Nelson García-Vázquez, et al., bioRxiv - Biochemistry 2024

  Quote: ... LC-3 (1:5,000, Novus Biological NB100–2220), p21 (1:1,000 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... LC-3 (Novus Biologicals, no. NB100-2220; 1:500), P62 (Novus Biologicals ...
• Met/HGFR triggers detrimental reactive microglia in TBI

  Rida Rehman, et al., bioRxiv - Neuroscience 2021

  Quote: ... Mouse anti-Integrin beta 3 (1:50, Novus biologicals), Guinea pig anti-Iba1 (1:500 ...
• Disruption of augmin-mediated microtubule nucleation in neural stem cells causes p53-dependent apoptosis and aborts brain development

  Ricardo Viais, et al., bioRxiv - Cell Biology 2020

  Quote: ... cleaved caspase-3 (Novus Biologicals #MAB835, dilution 1:500), γ-tubulin (ExBio ...
• TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation

  Stefano Sellitto, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Caspase 3 1:1000 (Novus Biologicals, NB100-56708), anti-GPX4 1:1000 (ab125066) ...
• Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2⁺ breast cancer

  Aaron G. Baugh, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-AE-1/AE-3 (1:200 dilution; Novus Biologicals, cat. NBP2-29429). Slides were then incubated with HRP-conjugated anti-rabbit secondary antibody (Leica Microsystems ...
• 3D microarchitecture of the human tuberculous granuloma

  Gordon Wells, et al., bioRxiv - Microbiology 2020

  Quote: ... 3-mercaptopyruvate sulfurtransferase (MPST; NBP1-82617, Novus Biologicals, 1:100), CD68 (M0814-CD68-KP1,DAKO,1:3000) ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-14-3-3ζ (Novus Biologicals, NBP2-24593SS, 1:1000). Following primary antibody incubation ...
• SNRK regulates TGFβ levels in atria to control cardiac fibrosis

  Karthikeyan Thirugnanam, et al., bioRxiv - Cell Biology 2024

  Quote: ... Smad 2/3 (Novus Biologicals, Cat# AF3797, 1:200 dilution), GAPDH (Santa Cruz ...
• Skp1 proteins are structural components of the synaptonemal complex in C. elegans

  Joshua Blundon, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-HIM-3 (rabbit polyclonal, 1:200 or 1:100; Novus Biologicals #53470002) or anti HTP-3 (chicken polyclonal ...
• RbAp46/48^LIN-53 and HAT-1 are required for initial CENP-A^HCP-3 deposition and de novo centromere formation in Caenorhabditis elegans embryos

  Zhongyang Lin, Karen Wing Yee Yuen, bioRxiv - Cell Biology 2020

  Quote: ... using rabbit (Rb)-anti-HCP-3 (1:1000; Novus biologicals 29540002), Rb-anti-KNL-2 (1:500 ...
• Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation

  Jack A. Bibby, et al., bioRxiv - Immunology 2022

  Quote: ... Arachidonic acid measurement was done using the human arachidonic acid ELISA kit (Novus biologicals) following manufacturer’s instructions ...
• Differentiation of Peritubular Myoid-Like Cells from Human Induced Pluripotent Stem Cells

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... 3 Beta- And Steroid Delta-Isomerase 1 (HSD3β, Novus Biologicals, NB110-7844) 1:200 ...
• A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem Cells

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... 3 Beta- And Steroid Delta-Isomerase 1 (HSD3β, Novus Biologicals, NB110-7844) 1:200 ...
• Microfluidic bioprinting for the in vitro generation of novel biomimetic human testicular tissues

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... 3 Beta- And Steroid Delta-Isomerase 1 (HSD3β, Novus Biologicals, NB110-7844) 1:200 ...
• Human TRMT2A methylates tRNA and contributes to translation fidelity

  Monika Witzenberger, et al., bioRxiv - Biochemistry 2023

  Quote: ... Primary antibody used: mouse anti-BirA (1:10; Novus Biologicals, #5B11c3-3). Secondary antibody used ...
• Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

  William L. Hwang, et al., bioRxiv - Genomics 2020

  Quote: ... 1:40 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), 1:40 anti-CD45-Alexa Fluor 594 (clone 2B11 + PD7/26 ...
• Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

  Xiaofei Zhang, et al., bioRxiv - Genomics 2023

  Quote: ... 1:20 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), and 1:100 anti-αSMA-Alexa Fluor 647 (clone 1A4 ...
• Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow’s milk, and infant formula products: moving towards next generation infant formula products

  Natalie P. Turner, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (1:5000, Rabbit polyclonal (Novus Biologicals (Invitro technologies), Melbourne ...
• Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9

  Chao Wang, et al., bioRxiv - Immunology 2024

  Quote: ... and mouse anti-pan-cytokeratin (Novus Biologicals, AE-1/AE-3, Cat# NBP2-29429). Finally ...
• Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics

  Victoria G Prior, et al., bioRxiv - Cancer Biology 2023

  Quote: ... cleaved Caspase 3 (1/200 dilution, Cell Signalling, MA, USA) and β1 integrin (1/50 dilution; Novus Biologicals, CO, USA). Primary antibodies diluted in blocking buffer were incubated overnight at 4°C ...
• Neuroretinal-derived caveolin-1 promotes endotoxin-induced inflammation in the murine retina

  Jami M. Gurley, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit polyclonal anti-TRAF3 (TNF Receptor-Associated Factor 3; 1:500; Novus Biologicals, #NBP-88639), and rabbit polyclonal anti-Gαt (Transducin ...
• Genetic control of neuronal activity enhances axonal growth only on permissive substrates

  Francina Mesquida-Veny, et al., bioRxiv - Neuroscience 2022

  Quote: ... followed by 3 O/N of primary antibody incubation (SCG-10 (1:1000, Novus Biologicals) in 2% BSA ...
• SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

  Akihiro Ikenaka, et al., bioRxiv - Cell Biology 2022

  Quote: ... Then the cells were labeled with antibodies against cleaved caspase-3 (1:20, CST #9602S) or Myogenin (1:20, Novus Biologicals #NBP2-33056). The following isotype controls were used ...
• Enteropathogenic Escherichia coli (EPEC) Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations and Increased Intestinal Permeability in a Murine Model

  Solanka E. Ledwaba, et al., bioRxiv - Microbiology 2020

  Quote: ... 1:1000, Thermo Fisher Scientific, PA1-183; mouse anti-claudin-2, 3:500, Invitrogen, 325600; rabbit anti-claudin-1, 1:1000, Novus biological, NBP1-77036) and secondary antibodies (Cy3-conjugated AffiniPure donkey anti-rabbit ...
• A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cells

  Hyeonji Lim, et al., bioRxiv - Bioengineering 2023

  Quote: ... The blots were incubated in PBS containing 0.1% Tween-20 and 3% BSA with anti-HIF1α antibody (1:1000) (AF1935, Novus Biologicals) or anti-beta actin antibody (1:1000 ...
• Hypercholesterolemia Impairs Clearance of Extracellular DNA and Promotes Inflammation and Atherosclerotic Plaque Progression

  Umesh Kumar Dhawan, et al., bioRxiv - Immunology 2020

  Quote: ... Samples were blocked with 3% FBS in 1X-PBS followed by incubation with anti-CitH3 antibody (1:100, NB100-571350, Novus Biologicals) and Alexa fluor 488-conjugated anti-rabbit antibody (1:1000 ...
• Cerebral Organoids In Primary Progressive Multiple Sclerosis Reveal Stem Cell Disruption And Failure To Produce Oligodendrocytes

  Nicolas Daviaud, et al., bioRxiv - Neuroscience 2022

  Quote: ... Slides were then incubated overnight at 4°C with the following primary antibodies diluted in blocking solution: rabbit anti-cleaved caspase 3 (1:200, Novus Biologicals), rat anti-CTIP2 (1:500 ...
• OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

  Daisuke Oikawa, et al., bioRxiv - Cell Biology 2021

  Quote: ... and OTUD1 (NBP1-90484, Novus Biologicals; 3 μg) were used.
• Myosin-1b interacts with UNC45A and controls intestinal epithelial morphogenesis

  Céline Revenu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Sections were incubated for 30 min at room temperature in blocking buffer (3% BSA in PBS) and then overnight at 4°C with anti Myo1b antibody (1:200, Novus Biologicals NBP1-87739) in blocking ...
• Lignin isolated by microwave-assisted acid-catalyzed solvolysis induced cell death on mammalian tumor cells by modulating apoptotic pathways

  Rio Kashimoto, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Sections were incubated with primary antibodies rabbit polyclonal anti-caspase 3 and rat monoclonal anti-CD31/PECAM-1 antibody (Novus Biologicals, Centennial, CO) in 1% normal goat serum ...
• A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem Cells

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-Insulin Like 3 (INSL3, Novus Biologicals, NBP1-81223) 1:500 ...
• Microfluidic bioprinting for the in vitro generation of novel biomimetic human testicular tissues

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-Insulin Like 3 (INSL3, Novus Biologicals, NBP1-81223) 1:500 ...
• iTie controls intestinal tolerance through suppressing the NLRP6 inflammasome

  Xiwen Qin, et al., bioRxiv - Immunology 2023

  Quote: ... Antibodies against lipoteichoic acid (NBP1-60146) and iTie (NBP1-98391) were from Novus Biologicals. Rabbit antibody against mouse iTie was generated by SinoBiological ...
• Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells

  Rui Santalla Méndez, et al., bioRxiv - Cell Biology 2023

  Quote: ... for 30 minutes prior to being incubated o/n and at 4 °C with specific antibodies against TNF-α (MACS miltenyi biotec, #130-091-649), Vamp-3 (Abcam #Ab5789, 1:200 final dilution, the ER marker PDI (Novus Biologicals #NBP2-02082), the Golgi cis/trans marker GM130 (BD transduction laboratories #610822) ...
• Auditory Hair Cells and Spiral Ganglion Neurons Regenerate Synapses with Refined Release Properties In Vitro

  Philippe F.Y. Vincent, et al., bioRxiv - Neuroscience 2023

  Quote: ... 50ng/ml of Neurotrophin-3 (NT3, Novus biologicals; #NBP1 99227), 50ng/ml of Brain Derived Neurotrophic Factor (BDNF ...
• The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

  Ugo Sardo, et al., bioRxiv - Physiology 2023

  Quote: ... Incubation with primary antibody was followed by 3 washes and membranes were incubated 2 hours with goat anti-Human IgG (Novus biological, NBP1-75006, 1/10000), goat anti-rabbit IgG (Cell signaling ...
• Leishmania amazonensis infection induces PD-L1 expression on dendritic cells in an mTor-dependent manner and impairs Th1 responses in vitro and in vivo

  Herbert L. de Matos Guedes, et al., bioRxiv - Immunology 2022

  Quote: ... and Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Novus Biologicals, Littleton, CO, USA). Primary antibodies were followed by HRP-conjugated secondary antibodies (Jackson ImmunoResearch Laboratories ...
• Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins

  Seraphine Kamayirese, et al., bioRxiv - Biophysics 2024

  Quote: The (His)6-14-3-3ε was from Novus Biologicals (Centennial, CO, USA). Thermal unfolding of 14-3-3 protein and 14-3-3 – peptide complexes were performed as previously described [30] ...
• Cell-intrinsic functions of the transcription factor Bhlhe40 in activated B cells and T follicular helper cells restrain the germinal center reaction and prevent lymphomagenesis

  René Rauschmeier, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μg of rabbit polyclonal anti-Bhlhe40 antibody (Novus Biologicals, NB100- 1800, lot C2) was added to 10 μl Protein G-coupled Dynabeads (Thermo Fisher Scientific ...
• Optimizing Phosphopeptide Structures That Target 14-3-3ε in Cutaneous Squamous Cell Carcinoma

  Seraphine Kamayirese, et al., bioRxiv - Biochemistry 2023

  Quote: (His)6-14-3-3ε was commercially obtained from Novus Biologicals (Centennial CO, USA), and 14-3-3ε-(His)12 was expressed in our laboratory (see details on protein expression in the supporting information) ...
• Epoxy fatty acid dysregulation and neuroinflammation in Alzheimer’s disease is resolved by a soluble epoxide hydrolase inhibitor

  Anamitra Ghosh, et al., bioRxiv - Neuroscience 2020

  Quote: ... Iba-1 (1:800, Wako or 1:500, Novus Biologicals), COX-2 (1:500 ...
• Amyloid beta acts synergistically as a pro-inflammatory cytokine

  Thomas J. LaRocca, et al., bioRxiv - Molecular Biology 2021

  Quote: ... ICAM-1 (Novus Biologicals, 1:2000); C3 (Novus ...
• Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

  Jennifer A Hollywood, et al., bioRxiv - Physiology 2021

  Quote: ... Havcr1 (1:100) (1-76701, Novus biologicals); CD68 (1:100 ...
• CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses

  Sallieu Jalloh, et al., bioRxiv - Immunology 2022

  Quote: ... primary MDMs from 3 different donors were pre-incubated with 20 μg/ml anti-CD169 antibody (HSn 7D2, Novus Biologicals) or IgG1k (P3.6.2.8.1 ...
• Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19

  Thais F. C. Fraga-Silva, et al., bioRxiv - Immunology 2022

  Quote: ... HMGB-1 was determined in the cell-free TA supernatants and in the supernatants of Calu-3 cultures using immunoassay following the manufacturer’s instructions (Novus Biologicals). Adenosine 5′-triphosphate (ATP ...
• Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow’s milk, and infant formula products: moving towards next generation infant formula products

  Natalie P. Turner, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-Syntenin 1 (SYN-1) (1:1000, Rabbit polyclonal (Novus Biologicals (Invitro technologies), Melbourne ...
• The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

  Mar Arias-Garcia, et al., bioRxiv - Cell Biology 2020

  Quote: ... Collagen I alpha 1 (Novus Biologicals, 1:500), Phospho-Histone H2A.X (Ser139 ...
• HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-HPL-1 (1:1000) (Novus Biologicals, 38620002), anti-HPL-2 (1:1000 ...
• PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-MRG-1 (1:1000) (Novus Biologicals, 49130002), anti-HDA-1 (1:2500 ...