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51 - 100 of 1440 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae

  Michael P. Motley, et al., bioRxiv - Immunology 2020

  Quote: ... at 1:500 or AF488-conjugated Mouse Anti-C5b-9 (ae11) (Novus Biologicals 5120AF488) at 1:150 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... LC-3 (Novus Biologicals, no. NB100-2220; 1:500), P62 (Novus Biologicals ...
• Disruption of augmin-mediated microtubule nucleation in neural stem cells causes p53-dependent apoptosis and aborts brain development

  Ricardo Viais, et al., bioRxiv - Cell Biology 2020

  Quote: ... cleaved caspase-3 (Novus Biologicals #MAB835, dilution 1:500), γ-tubulin (ExBio ...
• TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation

  Stefano Sellitto, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Caspase 3 1:1000 (Novus Biologicals, NB100-56708), anti-GPX4 1:1000 (ab125066) ...
• Enhanced anti-amyloid effect of combined leptin and pioglitazone in APP/PS1 transgenic mice

  Yao Liu, et al., bioRxiv - Neuroscience 2020

  Quote: ... or immunolabelled for Aβ plaques using the mouse anti-MOAβ-2 (1:1000; Novus Biologicals) antibody following antigen retrieval with formic acid (90% ...
• The GPR4 antagonist NE-52-QQ57 increases survival, mitigates the hyperinflammatory response and reduces viral load in SARS-CoV-2-infected K18-hACE2 transgenic mice

  Xin-Jun Wu, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... or SARS-CoV-2 specific anti- nucleocapsid antibody (Novus Biologicals, #NB100-56683, dilution 1:500) and horseradish peroxidase (HRP ...
• Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment

  Patience O. Obi, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-ATP7A (S60-4, Novus Biologicals, 1:200), rabbit anti-ITGA6 (3750 ...
• Epoxy fatty acid dysregulation and neuroinflammation in Alzheimer’s disease is resolved by a soluble epoxide hydrolase inhibitor

  Anamitra Ghosh, et al., bioRxiv - Neuroscience 2020

  Quote: ... Iba-1 (1:800, Wako or 1:500, Novus Biologicals), COX-2 (1:500 ...
• Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

  William L. Hwang, et al., bioRxiv - Genomics 2020

  Quote: ... 1:40 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), 1:40 anti-CD45-Alexa Fluor 594 (clone 2B11 + PD7/26 ...
• Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

  Xiaofei Zhang, et al., bioRxiv - Genomics 2023

  Quote: ... 1:20 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), and 1:100 anti-αSMA-Alexa Fluor 647 (clone 1A4 ...
• The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

  Ugo Sardo, et al., bioRxiv - Physiology 2023

  Quote: ... Incubation with primary antibody was followed by 3 washes and membranes were incubated 2 hours with goat anti-Human IgG (Novus biological, NBP1-75006, 1/10000), goat anti-rabbit IgG (Cell signaling ...
• Skeletal muscle-derived Human Mesenchymal Stem Cells: influence of different culture conditions on proliferative and myogenic capabilities

  Stefano Testa, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells are incubated with the primary antibody anti-myosin heavy chain (MF20, mouse monoclonal, DHSB, diluted 1:2) or anti-ki67 (rabbit polyclonal, Novus Biologicals #NB110-89717, diluted 1:200) for 1 h ...
• 3D microarchitecture of the human tuberculous granuloma

  Gordon Wells, et al., bioRxiv - Microbiology 2020

  Quote: ... 3-mercaptopyruvate sulfurtransferase (MPST; NBP1-82617, Novus Biologicals, 1:100), CD68 (M0814-CD68-KP1,DAKO,1:3000) ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-14-3-3ζ (Novus Biologicals, NBP2-24593SS, 1:1000). Following primary antibody incubation ...
• Amyloid beta acts synergistically as a pro-inflammatory cytokine

  Thomas J. LaRocca, et al., bioRxiv - Molecular Biology 2021

  Quote: ... ICAM-1 (Novus Biologicals, 1:2000); C3 (Novus ...
• Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain

  Javier Ganz, et al., bioRxiv - Neuroscience 2023

  Quote: ... one sample each for anti-CX43/GJA1 (Novus Biologicals, FAB7737R-1 00UG AF647), anti-SOX9 (Abcam ...
• Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in bacterial and mammalian cells

  Grace D. Galles, et al., bioRxiv - Biochemistry 2022

  Quote: ... Blots were subsequently probed for beta-actin using HRP-conjugated primary (AC-15, Novus Biologicals 1:2000) appx 3 hours in 5% milk in TBST ...
• Repression of Hypoxia-Inducible Factor-1 Contributes to Increased Mitochondrial Reactive Oxygen Species Production in Diabetes

  Xiaowei Zheng, et al., bioRxiv - Cell Biology 2021

  Quote: ... and then incubated overnight at 4°C with primary antibodies (HIF-1α antibody, GeneTex, GTX127309, 1:100 diluted; KIM-1 antibody, Novus Biologicals, NBP1-76701, 1:50 diluted). Sections were then washed with PBS-T four times for 5 minutes each ...
• CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia-induced invasion, and therapeutic resistance

  Jan C. Lumibao, et al., bioRxiv - Cancer Biology 2022

  Quote: ... GPx-4 (1:100, NBP2-75511, Novus Biologicals, Centennial, CO), and matrix metalloproteinase 2 (MMP-2 ...
• Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics

  Victoria G Prior, et al., bioRxiv - Cancer Biology 2023

  Quote: ... cleaved Caspase 3 (1/200 dilution, Cell Signalling, MA, USA) and β1 integrin (1/50 dilution; Novus Biologicals, CO, USA). Primary antibodies diluted in blocking buffer were incubated overnight at 4°C ...
• Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

  Jennifer A Hollywood, et al., bioRxiv - Physiology 2021

  Quote: ... Havcr1 (1:100) (1-76701, Novus biologicals); CD68 (1:100 ...
• RbAp46/48^LIN-53 and HAT-1 are required for initial CENP-A^HCP-3 deposition and de novo centromere formation in Caenorhabditis elegans embryos

  Zhongyang Lin, Karen Wing Yee Yuen, bioRxiv - Cell Biology 2020

  Quote: ... using rabbit (Rb)-anti-HCP-3 (1:1000; Novus biologicals 29540002), Rb-anti-KNL-2 (1:500 ...
• Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow’s milk, and infant formula products: moving towards next generation infant formula products

  Natalie P. Turner, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-Syntenin 1 (SYN-1) (1:1000, Rabbit polyclonal (Novus Biologicals (Invitro technologies), Melbourne ...
• Heterogeneity of Glycan Biomarker Clusters as an Indicator of Recurrence in Pancreatic Cancer

  Luke Wisniewski, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibodies against CA19-9 (clone 9L426, US Biological Life Sciences) and TRA-1-60 (Novus Biologicals) were labeled for immunofluorescent staining with Sulfo-Cyanine5 NHS ester and Sulfo-Cyanine3 NHS ester respectively ...
• Reversal of pathologic changes in fibroblasts from Niemann-Pick type C disease patients by inhibition of bromodomain and extraterminal proteins

  Martina Parente, et al., bioRxiv - Cell Biology 2023

  Quote: ... and then overnight at 4°C with primary antibodies (1% BSA in PBS) against NPC1 (1:2,500; NB400-148, Novus Biologicals) and LAMP2 (1:1,000 ...
• The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

  Mar Arias-Garcia, et al., bioRxiv - Cell Biology 2020

  Quote: ... Collagen I alpha 1 (Novus Biologicals, 1:500), Phospho-Histone H2A.X (Ser139 ...
• HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-HPL-1 (1:1000) (Novus Biologicals, 38620002), anti-HPL-2 (1:1000 ...
• PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-MRG-1 (1:1000) (Novus Biologicals, 49130002), anti-HDA-1 (1:2500 ...
• PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-HDA-1 (1:2500) (Novus Biologicals, 38660002), anti-LET-418 (1:1000 ...
• HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-MRG-1 (1:1000) (Novus Biologicals, 49130002), anti-HPL-1 (1:1000 ...
• HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans

  Heesun Kim, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-HDA-1 (1:2500) (Novus Biologicals, 38660002), anti-LET-418 (1:1000 ...
• Cerebral Organoids In Primary Progressive Multiple Sclerosis Reveal Stem Cell Disruption And Failure To Produce Oligodendrocytes

  Nicolas Daviaud, et al., bioRxiv - Neuroscience 2022

  Quote: ... Slides were then incubated overnight at 4°C with the following primary antibodies diluted in blocking solution: rabbit anti-cleaved caspase 3 (1:200, Novus Biologicals), rat anti-CTIP2 (1:500 ...
• Human TRMT2A methylates tRNA and contributes to translation fidelity

  Monika Witzenberger, et al., bioRxiv - Biochemistry 2023

  Quote: ... Primary antibody used: mouse anti-BirA (1:10; Novus Biologicals, #5B11c3-3). Secondary antibody used ...
• In silico transcriptomics identifies FDA-approved drugs and biological pathways for protection against cisplatin-induced hearing loss

  Pezhman Salehi, et al., bioRxiv - Neuroscience 2022

  Quote: ... Proteus Biosciences, used at 1:200), anti-otoferlin (HCS-1, DSHB 1:500) and anti-GFP (NB100-1614, Novus Biologicals 1:500).
• Repression of Hypoxia-Inducible Factor-1 Contributes to Increased Mitochondrial Reactive Oxygen Species Production in Diabetes

  Xiaowei Zheng, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-KIM-1 (1:500, NBP1-76701; Novus Biologicals) or anti-α-tubulin (1:1000 ...
• Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

  Jie Wang, Amir Rattner, Jeremy Nathans, bioRxiv - Immunology 2023

  Quote: ... rat anti-PU.1/Spi-1 (Novus Biologicals MAB7124); rat anti-CD180/RP105 antibody ...
• Misaligned chromosomes that satisfy the spindle assembly checkpoint are a strong predictor of micronuclei formation in dividing cancer cells

  Ana Margarida Gomes, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-WDHD1/And-1 (1:1000; Novus Biologicals), rabbit anti-Aurora-A (1:1000 ...
• Inflammation-mediated Upregulation of VCAM-1 but not KIM-1 during Acute Kidney Injury to Chronic Kidney Disease Transition

  Isabel Melchinger, et al., bioRxiv - Pathology 2022

  Quote: ... and KIM-1(#AF1817, Novus Biologicals, 1:100 dilution)(17) ...
• Alterations in neural stem cell quiescence and activation in the 3xTG-AD model of Alzheimer’s Disease

  Yubing Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... Sections were incubated overnight with primary antibodies in incubation buffer at 4°C (Hopx, 1:1000, HPA030180, Atlas Antibodies; Lpar1, 1:1000, NBP1-03363, Novus Biologicals; Sox2 ...
• NUAK1 regulates contraction in vascular smooth muscle cells derived from abdominal aortic aneurysm patients

  Karlijn B. Rombouts, et al., bioRxiv - Cell Biology 2024

  Quote: ... PDZ and LIM domain protein 4 (1:1000, NBP1-80833, Novus Biologicals), NUAK family kinase 1 (1:1000 ...
• SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

  Akihiro Ikenaka, et al., bioRxiv - Cell Biology 2022

  Quote: ... Then the cells were labeled with antibodies against cleaved caspase-3 (1:20, CST #9602S) or Myogenin (1:20, Novus Biologicals #NBP2-33056). The following isotype controls were used ...
• Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice

  Tejas R. Karhadkar, et al., bioRxiv - Immunology 2020

  Quote: ... and then incubated with 1 µg/ml biotin-conjugated F(ab’)2-donkey anti-rat antibodies (Novus Biologicals, Littleton, CO) in PBS-BSA for 30 minutes at room temperature ...
• Disrupting ACE2 Dimerization Mitigates the Infection by SARS-COV-2

  Jiaqi Zhu, Yue Su, Young Tang, bioRxiv - Molecular Biology 2022

  Quote: ... The membrane was blocked by 5% skim milk and incubated with ACE-2 Antibody (1:2,000, Novus Biologicals, CO, USA), 6xHN Polyclonal Antibody (1:2000 ...
• Profilin 1 deficiency drives mitotic defects and impairs genome stability

  Federica Scotto di Carlo, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Profilin 1 (Novus Biologicals, NB200-262, 1:100); mouse anti-Aurora B (BD Transduction Laboratories ...
• Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

  Julia E. Gerson, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Ubiquilin-1 (Novus biologicals, cat. #H00029979-M02; 1:2000) or anti-A1UP (Santa Cruz ...
• Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

  Julia E. Gerson, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Ubiquilin-1 (Novus biologicals, cat. #H00029979-M02; 1:2000), anti-A1UP for UBQLN4 (Santa Cruz ...
• Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

  Ngoc Lan Tran, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-LYVE-1 (dilution 1:300, rabbit polyclonal, Novus Biologicals) + anti-rabbit AF647 (dilution 1:200 ...
• Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma

  Arja Ray, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1:400 rabbit anti-CD31/PECAM-1 (Novus Biologicals, Human), 1:400 rabbit anti-RFP (Abcam ...
• Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation

  Pei Yee Tey, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Syntenin 1 (Novus Biologicals, H00006386-B01P, WB 1:1000), anti-TOMM20 (BD Transduction ...
• Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

  Michael J. Podolsky, et al., bioRxiv - Cell Biology 2023

  Quote: ... human procollagen I alpha 1 (1:1,500; Novus Biologicals: AF6220), MYC (1:5,000 ...